neural crest cell migration 0.0022525 protein disulfide oxidoreductase activity 0.0028453 nucleoside monophosphate metabolic process 0.0032009 neurotransmitter metabolic process 0.0034381 neuron fate commitment 0.0058684 ameboidal cell migration 0.0061055 response to interleukin-1 0.0068761 protein kinase cascade 0.0069354 amine biosynthetic process 0.0090694 pigment metabolic process 0.0092472 organic acid biosynthetic process 0.0093657 carboxylic acid biosynthetic process 0.0093657 glycoprotein binding 0.0094843 induction of apoptosis 0.0095436 iron ion binding 0.0098992 cyclin-dependent protein kinase regulator activity 0.010433 photoreceptor activity 0.01067 cell fate specification 0.011085 axon guidance 0.011203 myoblast differentiation 0.0115 induction of programmed cell death 0.011678 induction of programmed cell death 0.011678 phosphoric diester hydrolase activity 0.012033 phosphoric diester hydrolase activity 0.012033 positive regulation of signal transduction 0.012626 negative regulation of programmed cell death 0.013278 negative regulation of apoptosis 0.013278 cell wall macromolecule metabolic process 0.013337 positive regulation of cell communication 0.013634 cell maturation 0.013811 response to estrogen stimulus 0.014878 positive regulation of adaptive immune response 0.014938 cyclic-nucleotide phosphodiesterase activity 0.014938 digestive system process 0.015056 lung alveolus development 0.015234 phosphotransferase activity, nitrogenous group as acceptor 0.015945 eukaryotic cell surface binding 0.015945 cellular nitrogen compound biosynthetic process 0.016242 negative regulation of cell death 0.016598 negative regulation of programmed cell death 0.016598 negative regulation of neuron differentiation 0.016657 C-C chemokine receptor activity 0.017012 C-C chemokine binding 0.017012 delayed rectifier potassium channel activity 0.017072 regulation of multicellular organism growth 0.017605 brain development 0.01802 receptor signaling protein activity 0.018257 nucleoside monophosphate biosynthetic process 0.018317 3',5'-cyclic-nucleotide phosphodiesterase activity 0.018494 positive regulation of I-kappaB kinase/NF-kappaB cascade 0.018731 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 0.019146 response to virus 0.019206 male gamete generation 0.019502 spermatogenesis 0.019502 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 0.019739 response to organic cyclic substance 0.019976 protein homodimerization activity 0.020391 nucleotide metabolic process 0.020451 nucleoside phosphate metabolic process 0.020451 sensory perception of mechanical stimulus 0.02051 cell wall macromolecule catabolic process 0.020984 regulation of T cell differentiation 0.020984 regulation of transforming growth factor beta receptor signaling pathway 0.021043 regulation of fibroblast proliferation 0.021517 protein histidine kinase activity 0.022347 positive regulation of protein kinase cascade 0.022347 protein histidine kinase activity 0.022347 two-component sensor activity 0.022347 viral genome replication 0.022644 regulation of Rho GTPase activity 0.022881 regulation of I-kappaB kinase/NF-kappaB cascade 0.023296 cell surface binding 0.023889 induction of apoptosis by extracellular signals 0.024244 sensory perception of sound 0.024718 odontogenesis 0.024778 odontogenesis of dentine-containing tooth 0.024778 diacylglycerol binding 0.024778 oxidoreductase activity, acting on the CH-NH group of donors 0.025252 fatty acid metabolic process 0.025845 glycolipid biosynthetic process 0.025904 positive regulation of transforming growth factor beta receptor signaling pathway 0.026319 positive regulation of fibroblast proliferation 0.027386 regulation of cell-substrate adhesion 0.027386 nucleobase, nucleoside and nucleotide metabolic process 0.027623 midbrain development 0.027623 glycosaminoglycan catabolic process 0.027919 gamete generation 0.027979 cell growth 0.028038 patterning of blood vessels 0.028334 phospholipid transporter activity 0.028394 response to biotic stimulus 0.028453 gamete generation 0.028512 glycolipid metabolic process 0.028571 olfactory receptor activity 0.028631 sensory perception of smell 0.029046 regulation of phagocytosis 0.029461 regulation of neuron apoptosis 0.029698 keratin filament 0.029698 regulation of cell adhesion 0.030231 negative regulation of growth 0.030409 regulation of cell migration 0.030409 iron ion transport 0.030587 protein complex scaffold 0.030765 negative regulation of cytokine production 0.031417 regulation of gene-specific transcription 0.031772 cellular nitrogen compound catabolic process 0.031772 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 0.031832 regulation of lipid metabolic process 0.031891 neuron differentiation 0.032247 regulation of pathway-restricted SMAD protein phosphorylation 0.032306 cellular amino acid derivative metabolic process 0.032543 response to steroid hormone stimulus 0.032662 regulation of angiogenesis 0.032662 chemokine receptor activity 0.033017 G-protein chemoattractant receptor activity 0.033017 regulation of alpha-beta T cell activation 0.033076 post-embryonic development 0.033136 regulation of growth 0.033136 pigment biosynthetic process 0.033432 phospholipid-translocating ATPase activity 0.033788 aminophospholipid transporter activity 0.033788 glycosphingolipid metabolic process 0.034025 response to other organism 0.034143 response to other organism 0.034143 response to monosaccharide stimulus 0.03444 response to glucose stimulus 0.03444 response to hexose stimulus 0.03444 positive regulation of developmental process 0.034618 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 0.034736 regulation of lymphocyte differentiation 0.034736 regulation of cellular component movement 0.034736 blood vessel remodeling 0.034855 icosanoid biosynthetic process 0.034855 chemokine binding 0.035033 response to other organism 0.035803 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 0.035922 potassium channel regulator activity 0.036218 dopamine metabolic process 0.036337 behavioral interaction between organisms 0.036633 insulin receptor signaling pathway 0.036811 dicarboxylic acid metabolic process 0.037522 fibrillar collagen 0.037582 nucleotide catabolic process 0.037759 fatty acid biosynthetic process 0.038234 positive regulation of DNA replication 0.038945 regulation of leukocyte migration 0.039301 ethanolamine and derivative metabolic process 0.03936 heart morphogenesis 0.03936 anti-apoptosis 0.039715 odontogenesis 0.039893 heart development 0.040071 positive regulation of cell differentiation 0.04019 tissue homeostasis 0.040249 lipid transport 0.040723 MAPKKK cascade 0.040901 regulation of anti-apoptosis 0.041079 phospholipid transporter activity 0.041079 calcium-dependent cysteine-type endopeptidase activity 0.041197 positive regulation of lymphocyte differentiation 0.041316 NADP or NADPH binding 0.041316 carboxy-lyase activity 0.041375 positive regulation of T cell differentiation 0.041375 organ morphogenesis 0.041909 serine family amino acid metabolic process 0.042087 regulation of telomere maintenance 0.042916 flagellum 0.043154 detection of stimulus involved in sensory perception 0.043154 microtubule-based flagellum 0.043154 deoxyribonuclease activity 0.043687 actin polymerization or depolymerization 0.043865 icosanoid metabolic process 0.043865 intermediate filament cytoskeleton organization 0.044576 neutral amino acid transmembrane transporter activity 0.044754 transmembrane receptor protein kinase activity 0.045228 protein-chromophore linkage 0.045643 cytokine metabolic process 0.045643 regulation of cell growth 0.046592 cellular amino acid derivative biosynthetic process 0.047244 spermatid development 0.047362 ephrin receptor activity 0.04754 angiogenesis 0.047659 outer membrane 0.047718 antigen processing and presentation of peptide antigen 0.047836 cellular lipid catabolic process 0.047836 intermediate filament-based process 0.047955 thymus development 0.048311 negative regulation of muscle cell differentiation 0.048607 extracellular matrix part 0.048726 protein tyrosine kinase activity 0.048963 carbonate dehydratase activity 0.048963 positive regulation of cellular component movement 0.049496 regulation of DNA replication 0.049674 NAD or NADH binding 0.049911 glycoprotein catabolic process 0.050504 NADP metabolic process 0.050622 positive regulation of lipid catabolic process 0.0508 defense response to bacterium 0.051097 intermediate filament 0.051274 subsynaptic reticulum 0.051986 negative regulation of cell development 0.052164 positive regulation of cell-substrate adhesion 0.052519 response to bacterium 0.052875 response to bacterium 0.052875 antigen processing and presentation of peptide antigen via MHC class I 0.052993 anatomical structure homeostasis 0.05329 negative regulation of angiogenesis 0.053468 response to peptide hormone stimulus 0.053764 positive regulation of DNA metabolic process 0.05406 regulation of JAK-STAT cascade 0.054179 chemokine receptor binding 0.054179 transmembrane receptor protein tyrosine kinase activity 0.054594 vitamin B6 binding 0.05495 pyridoxal phosphate binding 0.05495 positive regulation of bone mineralization 0.055305 regulation of skeletal muscle tissue development 0.055424 negative regulation of developmental process 0.055661 sulfate transmembrane transporter activity 0.05572 cellular amino acid biosynthetic process 0.055898 regulation of erythrocyte differentiation 0.056017 negative regulation of cell growth 0.056135 transforming growth factor beta receptor binding 0.056135 developmental maturation 0.056432 guanyl-nucleotide exchange factor activity 0.056669 lipid catabolic process 0.057084 branching morphogenesis of a tube 0.057143 fatty acid transport 0.057143 chemokine activity 0.05738 regulation of neurotransmitter levels 0.057973 protein oligomerization 0.058032 regulation of locomotion 0.058151 intramolecular transferase activity 0.058447 regulation of protein kinase B signaling cascade 0.058921 regulation of cell-matrix adhesion 0.059632 response to bacterium 0.05981 positive regulation of cell migration 0.05987 monocarboxylic acid metabolic process 0.060047 cell-substrate junction assembly 0.060344 mitochondrial envelope 0.060522 nucleobase biosynthetic process 0.06064 dicarboxylic acid transmembrane transporter activity 0.060759 positive regulation of interleukin-1 beta secretion 0.061055 positive regulation of interleukin-1 beta production 0.061055 receptor complex 0.061114 morphogenesis of a branching structure 0.061352 apical part of cell 0.061648 phospholipid binding 0.062063 polysaccharide catabolic process 0.062359 tube morphogenesis 0.062774 negative regulation of neuron apoptosis 0.063071 dicarboxylic acid transport 0.06313 RNA polymerase II transcription factor activity, enhancer binding 0.06313 transcription factor activity 0.06313 regulation of protein catabolic process 0.063189 formation of primary germ layer 0.063485 regulation of alpha-beta T cell differentiation 0.063604 enzyme linked receptor protein signaling pathway 0.063663 cellular biogenic amine biosynthetic process 0.063723 regulation of chromosome organization 0.064019 positive regulation of growth 0.064078 vitamin binding 0.064375 nucleotide biosynthetic process 0.064493 drug binding 0.066627 negative regulation of neurogenesis 0.066686 Cajal body 0.066746 positive regulation of leukocyte migration 0.067101 antigen processing and presentation 0.067101 electron transport chain 0.067457 desmosome 0.067516 regulation of generation of precursor metabolites and energy 0.067813 positive regulation of endocytosis 0.067813 cysteine-type endopeptidase inhibitor activity 0.068168 vascular process in circulatory system 0.068228 protein kinase C binding 0.068583 peptide cross-linking 0.068761 regulation of bone mineralization 0.069057 regulation of blood vessel size 0.069117 response to heat 0.069117 regulation of tube size 0.069117 protein serine/threonine/tyrosine kinase activity 0.069235 collagen fibril organization 0.069354 muscle system process 0.069769 GTPase binding 0.069828 glutamine family amino acid biosynthetic process 0.070065 negative regulation of microtubule polymerization or depolymerization 0.070243 cell fate commitment 0.070362 alcohol binding 0.070362 regulation of protein kinase cascade 0.070717 voltage-gated anion channel activity 0.070895 transmembrane receptor protein tyrosine kinase signaling pathway 0.071251 receptor signaling protein serine/threonine kinase activity 0.071369 positive regulation of cellular carbohydrate metabolic process 0.071606 positive regulation of carbohydrate metabolic process 0.071606 organelle outer membrane 0.072081 receptor-mediated endocytosis 0.072258 extracellular matrix structural constituent 0.072318 regulation of blood pressure 0.072496 reproductive process in a multicellular organism 0.072733 hydro-lyase activity 0.072792 wound healing 0.073207 negative regulation of cell differentiation 0.073385 organic alcohol transport 0.074037 pyridine nucleotide biosynthetic process 0.074215 gonad development 0.074274 structural constituent of cytoskeleton 0.074274 leukotriene metabolic process 0.074392 endonuclease activity 0.07457 mitochondrial outer membrane 0.074748 serine-type endopeptidase inhibitor activity 0.074985 axon ensheathment 0.075222 ensheathment of neurons 0.075222 aminoglycan catabolic process 0.075282 cytokine biosynthetic process 0.075282 cofactor binding 0.075459 nucleotide-excision repair 0.075519 negative regulation of cell adhesion 0.07623 mannose binding 0.076349 hemostasis 0.076763 male gonad development 0.076823 negative regulation of gene-specific transcription 0.07706 response to abiotic stimulus 0.077297 embryonic development 0.077356 alkene biosynthetic process 0.077475 leukotriene biosynthetic process 0.077475 hemopoiesis 0.077593 positive regulation of pathway-restricted SMAD protein phosphorylation 0.078008 lyase activity 0.078245 establishment or maintenance of apical/basal cell polarity 0.078838 platelet-derived growth factor receptor signaling pathway 0.079609 positive regulation of gene-specific transcription 0.079727 cell-substrate adherens junction 0.079905 peptidyl-serine modification 0.080083 eye morphogenesis 0.080379 epidermal cell differentiation 0.080379 positive regulation of protein import into nucleus 0.080676 focal adhesion formation 0.080735 cell fate determination 0.080735 collagen catabolic process 0.081091 collagen 0.081269 regulation of kinase activity 0.081387 glutamine family amino acid metabolic process 0.081446 keratinization 0.082098 unsaturated fatty acid biosynthetic process 0.082098 kidney development 0.082988 exosome (RNase complex) 0.083462 nucleobase metabolic process 0.08358 hyaluronic acid binding 0.08364 positive regulation of cell activation 0.083817 lipid transporter activity 0.083936 negative regulation of lipid metabolic process 0.084055 basement membrane 0.084351 liver development 0.084588 regulation of transmembrane transport 0.084647 regulation of transferase activity 0.085062 selenium binding 0.085359 negative regulation of hydrolase activity 0.085477 regulation of BMP signaling pathway 0.085833 positive regulation of innate immune response 0.085892 ribonucleoside monophosphate biosynthetic process 0.086248 ribonucleoside monophosphate metabolic process 0.086248 deoxyribonucleotide metabolic process 0.086544 deoxyribonucleotide metabolic process 0.086544 deoxyribonucleotide metabolic process 0.086544 L-ascorbic acid binding 0.086722 axon guidance 0.086841 regulation of cell division 0.087374 behavioral defense response 0.087433 fear response 0.087433 behavioral fear response 0.087433 cellular alkene metabolic process 0.087967 response to alkaloid 0.088026 organic cation transport 0.088026 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 0.088085 glycerolipid biosynthetic process 0.088382 somatic diversification of immune receptors 0.088441 drug transport 0.088441 natural killer cell activation 0.0885 regulation of heart rate 0.088915 regulation of lipid catabolic process 0.089034 regulation of cell activation 0.089627 adult locomotory behavior 0.089686 positive regulation of cell development 0.089923 low-density lipoprotein receptor activity 0.090634 regulation of fatty acid oxidation 0.091405 protein amino acid ADP-ribosylation 0.091583 cell-substrate junction 0.091583 stereocilium 0.092887 positive regulation of cytokine production 0.093183 muscle contraction 0.093361 cholesterol efflux 0.093539 NAD+ ADP-ribosyltransferase activity 0.093539 protein import into nucleus, translocation 0.093954 regulation of leukocyte proliferation 0.094013 regulation of mononuclear cell proliferation 0.094013 focal adhesion 0.094132 coagulation 0.094369 blood coagulation 0.094369 regulation of neurogenesis 0.094487 phagocytosis 0.095139 disulfide oxidoreductase activity 0.095317 generation of precursor metabolites and energy 0.095376 cellular biogenic amine metabolic process 0.095436 regulation of interleukin-12 production 0.095495 neutral amino acid transport 0.096147 MHC protein binding 0.096503 Rho GTPase binding 0.09668 anion:cation symporter activity 0.096799 endocytosis 0.097095 endocytosis 0.097095 platelet activation 0.097214 heme metabolic process 0.097392 estrogen receptor binding 0.097688 negative regulation of catalytic activity 0.098103 purinergic nucleotide receptor activity, G-protein coupled 0.098162 smooth muscle contraction 0.098577 extracellular matrix 0.098755 glial cell differentiation 0.098814 bacterial binding 0.099052 extracellular matrix binding 0.099111 actin filament 0.099467 muscle homeostasis 0.099526 oxidoreductase activity, acting on the CH-NH2 group of donors 0.099585 respiratory chain 0.1 regulation of chondrocyte differentiation 0.10012 transferase activity, transferring amino-acyl groups 0.10071 potassium ion binding 0.10077 transmembrane receptor protein serine/threonine kinase activity 0.10083 transforming growth factor beta receptor activity 0.10083 negative regulation of gene-specific transcription from RNA polymerase II promoter 0.10101 very-long-chain fatty acid metabolic process 0.10101 ATPase binding 0.1013 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 0.10148 regulation of transmembrane transporter activity 0.1016 vasculogenesis 0.10196 adherens junction 0.10249 carboxylic acid binding 0.10261 regulation of microtubule depolymerization 0.10296 negative regulation of microtubule depolymerization 0.10296 regulation of lymphocyte proliferation 0.1035 Ras protein signal transduction 0.10421 growth factor binding 0.10421 collagen binding 0.10421 regulation of tyrosine phosphorylation of STAT protein 0.10445 organelle subcompartment 0.10451 anatomical structure formation involved in morphogenesis 0.10451 2 iron, 2 sulfur cluster binding 0.1048 regulation of ion transport 0.10611 neuron development 0.10682 regulation of nitric-oxide synthase activity 0.10688 multicellular organismal homeostasis 0.10694 DNA damage response, signal transduction by p53 class mediator 0.10747 ion homeostasis 0.10765 sarcomere 0.108 regulation of protein kinase activity 0.10812 regulation of cyclin-dependent protein kinase activity 0.10812 positive regulation of lymphocyte activation 0.10818 lipoprotein receptor activity 0.10824 response to glucocorticoid stimulus 0.10836 negative regulation of molecular function 0.10842 cellular aromatic compound metabolic process 0.1086 regulation of ion transmembrane transport 0.10865 cytolysis 0.10901 negative regulation of binding 0.10925 axon ensheathment 0.10925 myelination 0.10925 rhythmic process 0.10972 glutamine family amino acid catabolic process 0.11037 integrin binding 0.11061 amine transmembrane transporter activity 0.11073 positive regulation of fatty acid metabolic process 0.11097 sterol metabolic process 0.1112 regulation of protein binding 0.11138 lipid catabolic process 0.11138 positive regulation of Ras GTPase activity 0.11138 regulation of interferon-gamma biosynthetic process 0.11144 regulation of T cell mediated immunity 0.11168 regulation of nervous system development 0.11168 pseudouridine synthesis 0.11191 regulation of fatty acid metabolic process 0.11257 unsaturated fatty acid metabolic process 0.11286 regulation of cellular ketone metabolic process 0.11352 regulation of protein import into nucleus 0.11369 endocrine pancreas development 0.11393 myeloid leukocyte activation 0.11399 coenzyme binding 0.11399 positive regulation of cell division 0.11405 aromatic amino acid family metabolic process 0.11411 regulation of innate immune response 0.11423 neuromuscular process 0.11452 positive regulation of cellular component organization 0.11482 Rho guanyl-nucleotide exchange factor activity 0.11494 positive regulation of multicellular organism growth 0.11529 regulation of anatomical structure size 0.11547 solute:hydrogen antiporter activity 0.11565 pyrimidine nucleotide metabolic process 0.11577 blood vessel morphogenesis 0.11606 cytokine-mediated signaling pathway 0.11636 envelope 0.11654 organelle envelope 0.11654 induction of apoptosis by intracellular signals 0.11654 positive regulation of locomotion 0.11672 positive regulation of biomineral formation 0.11683 MAP kinase kinase activity 0.11689 SNARE complex 0.11701 cell-cell adherens junction 0.11725 positive regulation of leukocyte activation 0.11731 lactation 0.11743 amino acid binding 0.11778 group transfer coenzyme metabolic process 0.11778 glutamate metabolic process 0.11891 oxidoreductase activity, acting on NADH or NADPH 0.11932 regulation of anatomical structure morphogenesis 0.11956 regulation of skeletal muscle fiber development 0.11974 low-density lipoprotein binding 0.12009 protein polyubiquitination 0.12092 specific transcriptional repressor activity 0.12128 regulation of lymphocyte activation 0.12164 regulation of protein amino acid phosphorylation 0.12175 folic acid and derivative metabolic process 0.12181 connexon complex 0.12199 O-acyltransferase activity 0.12229 non-G-protein coupled 7TM receptor activity 0.12247 positive regulation of alpha-beta T cell activation 0.12253 lipid biosynthetic process 0.12258 negative regulation of organelle organization 0.12282 fatty acid biosynthetic process 0.12336 regulation of axon extension 0.12347 positive regulation of interleukin-1 secretion 0.12371 diacylglycerol kinase activity 0.12377 arginine metabolic process 0.12401 transferase activity, transferring pentosyl groups 0.12407 transmembrane receptor protein serine/threonine kinase signaling pathway 0.12407 glycogen metabolic process 0.12424 cornified envelope 0.1243 brush border membrane 0.12436 DNA-directed RNA polymerase II, core complex 0.12442 positive regulation of intracellular transport 0.12448 eye morphogenesis 0.12466 oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor 0.12507 protein serine/threonine kinase activity 0.12567 cell junction assembly 0.12614 proteinaceous extracellular matrix 0.12632 aging 0.12632 WW domain binding 0.12644 endocrine process 0.12673 regulation of systemic arterial blood pressure by hormone 0.12673 amine catabolic process 0.12673 regulation of systemic arterial blood pressure mediated by a chemical signal 0.12673 regulation of systemic arterial blood pressure 0.12673 viral reproductive process 0.12685 regulation of interleukin-1 beta secretion 0.12691 purine base metabolic process 0.12709 fear response 0.12715 cation:amino acid symporter activity 0.12774 mesoderm formation 0.1278 response to carbohydrate stimulus 0.1278 dicarboxylic acid transmembrane transporter activity 0.12798 dicarboxylic acid transmembrane transporter activity 0.12798 cyclic nucleotide metabolic process 0.12804 response to reactive oxygen species 0.12804 flagellum 0.12869 phosphoinositide binding 0.12881 protein tetramerization 0.12899 osteoblast differentiation 0.1291 carbohydrate homeostasis 0.12934 glucose homeostasis 0.12934 response to organic nitrogen 0.12934 response to amine stimulus 0.12934 positive regulation of homeostatic process 0.1297 activation of pro-apoptotic gene products 0.12982 cyclin-dependent protein kinase activity 0.13035 cytokine activity 0.13065 CoA hydrolase activity 0.13071 oxidoreductase activity, acting on sulfur group of donors 0.13088 regulation of cholesterol transport 0.13088 regulation of sterol transport 0.13088 regulation of leukocyte activation 0.13159 regulation of adaptive immune response 0.13302 lung development 0.13308 detection of external stimulus 0.1332 membrane protein proteolysis 0.13325 G-protein-coupled receptor binding 0.13361 epidermal cell differentiation 0.13379 single fertilization 0.13379 extracellular matrix organization 0.13408 cell morphogenesis 0.13426 regulation of gene-specific transcription from RNA polymerase II promoter 0.13438 cellular amine metabolic process 0.13444 protein maturation 0.13485 heterocycle catabolic process 0.13545 positive regulation of angiogenesis 0.13551 aromatase activity 0.13568 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 0.13568 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 0.13568 NADH dehydrogenase (ubiquinone) activity 0.1358 NADH dehydrogenase (quinone) activity 0.1358 NADH dehydrogenase activity 0.1358 protein amino acid O-linked glycosylation 0.13592 regulation of Wnt receptor signaling pathway 0.13669 positive regulation of neurogenesis 0.13782 monocarboxylic acid transport 0.13782 regulation of metal ion transport 0.13823 peripheral nervous system development 0.13853 ureteric bud development 0.13871 neurotransmitter:sodium symporter activity 0.13883 axonogenesis 0.13912 caspase regulator activity 0.13936 positive regulation of alpha-beta T cell differentiation 0.13942 amine transmembrane transporter activity 0.13948 anchoring junction 0.13954 response to tumor necrosis factor 0.13989 response to corticosteroid stimulus 0.14001 regulation of cell development 0.14013 circulatory system process 0.14013 cellular response to peptide hormone stimulus 0.14019 regulation of translational initiation 0.14043 JNK cascade 0.14055 NADH dehydrogenase complex 0.1406 NADH dehydrogenase complex 0.1406 NADH dehydrogenase complex 0.1406 respiratory chain complex I 0.1406 respiratory chain complex I 0.1406 NADH dehydrogenase complex 0.1406 NADH dehydrogenase complex 0.1406 mitochondrial respiratory chain complex I 0.1406 NADH dehydrogenase complex 0.1406 NADH dehydrogenase complex 0.1406 SMAD binding 0.14108 positive regulation of neuron differentiation 0.1412 ovulation cycle process 0.14155 hydrogen ion transmembrane transporter activity 0.14155 positive regulation of cell cycle 0.14185 DNA damage response, signal transduction resulting in induction of apoptosis 0.14191 Wnt receptor signaling pathway 0.14232 RNA 3'-end processing 0.1425 response to hypoxia 0.1425 response to oxygen levels 0.1428 regulation of neuron differentiation 0.1428 purine nucleotide catabolic process 0.14315 sialyltransferase activity 0.14339 long-chain fatty acid transport 0.14428 Golgi-associated vesicle 0.14475 response to oxidative stress 0.14487 positive regulation of interleukin-2 biosynthetic process 0.14505 regulated secretory pathway 0.14606 defense response to Gram-positive bacterium 0.14665 rRNA metabolic process 0.14695 embryonic development 0.14701 embryonic development ending in birth or egg hatching 0.14701 endopeptidase inhibitor activity 0.14713 cellular amino acid and derivative metabolic process 0.14718 regulation of protein stability 0.14736 regulation of heart contraction 0.14766 positive regulation of cellular catabolic process 0.1479 positive regulation of transmission of nerve impulse 0.14795 ribonuclease activity 0.14813 cell migration 0.14813 DNA damage response, signal transduction by p53 class mediator 0.14843 ribonucleoside metabolic process 0.14861 carboxylic acid transport 0.14873 antiporter activity 0.14878 water transporter activity 0.14902 electron carrier activity 0.14932 positive regulation of protein complex assembly 0.14938 regulation of tyrosine phosphorylation of Stat3 protein 0.14967 cellular glucan metabolic process 0.14979 cellular amino acid derivative catabolic process 0.14979 glucan metabolic process 0.14979 amino acid transmembrane transporter activity 0.14985 positive regulation of T cell activation 0.14997 nuclease activity 0.15021 PML body 0.1505 rRNA processing 0.15086 positive regulation of kinase activity 0.15104 regulation of chemotaxis 0.15133 positive regulation of osteoblast differentiation 0.15139 regulation of binding 0.15175 neurotransmitter transporter activity 0.15193 hydrolase activity, hydrolyzing O-glycosyl compounds 0.1521 cytoskeletal adaptor activity 0.15234 positive regulation of transferase activity 0.15282 response to insulin stimulus 0.15299 regulation of receptor-mediated endocytosis 0.15305 spliceosomal snRNP assembly 0.15329 palate development 0.15341 positive regulation of ossification 0.15376 solute:solute antiporter activity 0.15412 amino acid transmembrane transporter activity 0.15412 cell killing 0.15465 positive regulation of protein kinase activity 0.15471 cellular ion homeostasis 0.15483 cofactor transport 0.15578 cellular response to insulin stimulus 0.15584 regulation of ion transmembrane transporter activity 0.15596 muscle tissue development 0.15625 water-soluble vitamin biosynthetic process 0.15655 regulation of carbohydrate biosynthetic process 0.15661 positive regulation of leukocyte mediated immunity 0.15673 positive regulation of lymphocyte mediated immunity 0.15673 T cell selection 0.1572 transforming growth factor beta receptor signaling pathway 0.15768 regulation of intracellular protein transport 0.15809 positive regulation of protein catabolic process 0.15827 regulation of glycogen metabolic process 0.15845 regulation of polysaccharide metabolic process 0.15845 stem cell maintenance 0.15868 muscle organ development 0.1594 carboxylesterase activity 0.15975 carboxylesterase activity 0.15975 carboxylesterase activity 0.15975 positive regulation of chemotaxis 0.15981 negative regulation of epithelial cell proliferation 0.16028 negative regulation of transcription from RNA polymerase II promoter 0.1604 exocytosis 0.16046 exocytosis 0.16046 killing of cells of another organism 0.16052 negative regulation of immune effector process 0.16064 endodeoxyribonuclease activity 0.16064 AMP binding 0.16082 vitamin biosynthetic process 0.16088 PDZ domain binding 0.16088 nucleotide receptor activity, G-protein coupled 0.16094 respiratory electron transport chain 0.16111 cell junction organization 0.16129 reproductive structure development 0.16135 embryonic organ development 0.16141 multicellular organismal catabolic process 0.16159 C21-steroid hormone metabolic process 0.16194 tumor necrosis factor receptor binding 0.16206 positive regulation of neuron apoptosis 0.16218 axon part 0.1623 sphingolipid catabolic process 0.16283 membrane lipid catabolic process 0.16283 integral to Golgi membrane 0.16289 regulation of cellular carbohydrate metabolic process 0.16301 somatic diversification of immunoglobulins 0.16307 body fluid secretion 0.16349 phospholipase C activity 0.16372 protein amino acid N-linked glycosylation 0.16378 MAP kinase activity 0.16396 regulation of osteoclast differentiation 0.16443 neuromuscular process controlling balance 0.16443 multicellular organismal response to stress 0.16509 metal cluster binding 0.16509 iron-sulfur cluster binding 0.16509 regulation of neurotransmitter transport 0.16509 phosphoinositide biosynthetic process 0.16515 phosphate binding 0.16526 negative regulation of MAPKKK cascade 0.1655 basolateral plasma membrane 0.16574 artery morphogenesis 0.16598 microtubule-based transport 0.16615 peptide biosynthetic process 0.16615 translational initiation 0.16627 mitochondrial electron transport, NADH to ubiquinone 0.16639 Ras guanyl-nucleotide exchange factor activity 0.16639 peptidase inhibitor activity 0.16675 regulation of cell morphogenesis 0.16698 negative regulation of cytokine biosynthetic process 0.16769 amino acid transport 0.16823 organic acid transport 0.16823 kinase binding 0.16852 chondroitin sulfate metabolic process 0.16864 regulation of glucose import 0.1687 growth 0.16876 phospholipid transport 0.16882 deacetylase activity 0.16918 regulation of biomineral formation 0.16941 protein complex binding 0.16965 regulation of pH 0.17001 peroxidase activity 0.17072 peroxidase activity 0.17072 peroxidase activity 0.17072 axon cargo transport 0.17137 response to cold 0.17167 organelle assembly 0.17208 GPI anchor metabolic process 0.17267 protein kinase binding 0.17291 regulation of mast cell proliferation 0.17309 regulation of B cell proliferation 0.17309 telomere organization 0.17327 regulation of fatty acid metabolic process 0.17398 response to estradiol stimulus 0.17427 positive regulation of lipid metabolic process 0.17457 negative regulation of signal transduction 0.17493 regulation of T cell activation 0.17516 negative regulation of locomotion 0.17516 monovalent inorganic cation homeostasis 0.1757 renal system process 0.17599 base-excision repair 0.17664 temperature homeostasis 0.17676 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 0.17682 ceramide metabolic process 0.17682 positive regulation of cell adhesion 0.17706 G1/S transition of mitotic cell cycle 0.17753 channel regulator activity 0.17789 chordate embryonic development 0.17789 fatty acid catabolic process 0.17795 negative regulation of Wnt receptor signaling pathway 0.17795 positive regulation of glucose metabolic process 0.17819 actin filament organization 0.17825 neuromuscular junction 0.1789 rRNA transcription 0.17931 transcription from RNA polymerase III promoter 0.17943 reciprocal meiotic recombination 0.17967 nucleotide receptor activity 0.1802 stress-activated protein kinase signaling pathway 0.1802 purinergic nucleotide receptor activity 0.1802 guanyl-nucleotide exchange factor activity 0.18026 endomembrane system 0.18026 guanyl-nucleotide exchange factor activity 0.18026 NF-kappaB binding 0.1805 integrin-mediated signaling pathway 0.18056 regulation of cellular catabolic process 0.18085 carbohydrate kinase activity 0.18097 solute:cation symporter activity 0.18103 negative regulation of ion transport 0.18109 positive regulation of transport 0.18109 negative regulation of cell cycle 0.18145 positive regulation of calcium ion transport into cytosol 0.18162 amine transport 0.18198 embryonic organ morphogenesis 0.18204 carbon-carbon lyase activity 0.18222 exocytosis 0.18228 regulation of cell morphogenesis involved in differentiation 0.18239 positive regulation of developmental growth 0.18263 negative regulation of BMP signaling pathway 0.1834 Rho protein signal transduction 0.18364 aminoglycan biosynthetic process 0.18465 membrane protein ectodomain proteolysis 0.18518 cytokine receptor binding 0.1856 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 0.18577 regulation of glucan biosynthetic process 0.18577 regulation of polysaccharide biosynthetic process 0.18577 regulation of glycogen biosynthetic process 0.18577 dioxygenase activity 0.18577 folic acid binding 0.18583 cellular chemical homeostasis 0.18589 voltage-gated sodium channel complex 0.18625 lipid localization 0.18654 lipid storage 0.18654 regulation of T cell proliferation 0.18666 glycosaminoglycan biosynthetic process 0.18743 fructose metabolic process 0.18785 water transport 0.18844 fluid transport 0.18844 carbon-oxygen lyase activity 0.1885 extracellular structure organization 0.18868 mismatch repair 0.1888 regulation of calcium ion transport 0.1888 release of cytochrome c from mitochondria 0.18886 racemase and epimerase activity 0.18939 energy reserve metabolic process 0.1898 in utero embryonic development 0.1901 exoribonuclease activity, producing 5'-phosphomonoesters 0.19022 exoribonuclease activity 0.19022 positive regulation of epidermal growth factor receptor signaling pathway 0.19028 nucleoside metabolic process 0.19057 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 0.19129 replication fork 0.19158 protein tyrosine phosphatase activity 0.19182 pseudouridine synthase activity 0.19194 amino acid transport 0.19218 carboxylesterase activity 0.19223 positive regulation of tyrosine phosphorylation of STAT protein 0.19324 trans-Golgi network 0.19378 protein amino acid autophosphorylation 0.19384 activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway 0.19407 regulation of cell-cell adhesion 0.19413 negative regulation of translation 0.19461 misfolded or incompletely synthesized protein catabolic process 0.19461 organic acid catabolic process 0.19472 carboxylic acid catabolic process 0.19472 cellular defense response 0.19508 inositol or phosphatidylinositol phosphodiesterase activity 0.19579 phosphoinositide phospholipase C activity 0.19579 phospholipase C activity 0.19579 microvillus 0.19615 sterol biosynthetic process 0.19632 heterocycle metabolic process 0.19644 T cell receptor signaling pathway 0.19686 nucleoside triphosphate catabolic process 0.1971 regulation of smooth muscle contraction 0.19721 positive regulation of binding 0.19721 positive regulation of translation 0.19745 protein homooligomerization 0.1981 monovalent inorganic cation transmembrane transporter activity 0.19893 phosphatase regulator activity 0.19947 positive regulation of glycogen metabolic process 0.19959 regulation of small GTPase mediated signal transduction 0.19964 low-density lipoprotein receptor binding 0.1997 occluding junction 0.2 tight junction 0.2 cell development 0.20006 steroid catabolic process 0.20006 feeding behavior 0.20047 forebrain development 0.20077 cellular component morphogenesis 0.20136 regulation of cell cycle 0.20136 regulation of vasodilation 0.20166 negative regulation of cellular component movement 0.2019 lysosome 0.20225 lytic vacuole 0.20225 pancreatic ribonuclease activity 0.20255 glucose metabolic process 0.2029 vacuole 0.20302 SH3 domain binding 0.20308 positive regulation of anti-apoptosis 0.20344 dorsal/ventral pattern formation 0.20368 intrinsic to Golgi membrane 0.20391 response to drug 0.20391 drug transporter activity 0.20403 regulation of cell cycle 0.20451 hormone activity 0.20468 solute:cation antiporter activity 0.20498 regulation of caspase activity 0.20516 caspase activator activity 0.20516 regulation of protein modification process 0.20522 cation:cation antiporter activity 0.20522 negative regulation of cell communication 0.20581 somatic diversification of immune receptors via germline recombination within a single locus 0.20593 somatic cell DNA recombination 0.20593 positive regulation of immune effector process 0.20599 transferase activity, transferring glycosyl groups 0.20622 phosphoprotein phosphatase activity 0.20634 mRNA export from nucleus 0.20634 cell part morphogenesis 0.20646 establishment of chromosome localization 0.20652 tissue morphogenesis 0.20729 spliceosomal complex 0.20735 positive regulation of leukocyte proliferation 0.20765 positive regulation of mononuclear cell proliferation 0.20765 response to ethanol 0.20771 inorganic cation transmembrane transporter activity 0.20788 positive regulation of transcription from RNA polymerase II promoter 0.20806 Notch signaling pathway 0.20806 sarcoplasmic reticulum 0.2083 alcohol catabolic process 0.2083 nucleolar part 0.20871 negative regulation of cell migration 0.20919 oxidoreductase activity, acting on CH-OH group of donors 0.20925 isoprenoid metabolic process 0.20954 isoprenoid metabolic process 0.20954 vitamin D receptor binding 0.21031 mitochondrial large ribosomal subunit 0.21073 organellar large ribosomal subunit 0.21073 regulation of transporter activity 0.21085 microspike assembly 0.21091 lamellipodium 0.2115 positive regulation of response to external stimulus 0.21156 positive regulation of interleukin-6 production 0.21162 regulation of cyclase activity 0.21191 alkali metal ion binding 0.21221 steroid hormone receptor binding 0.21292 embryonic placenta development 0.21316 protein domain specific binding 0.2134 translation initiation factor activity 0.21375 regulation of JUN kinase activity 0.21381 photoreceptor cell development 0.21405 photoreceptor cell development 0.21405 eye photoreceptor cell development 0.21405 pyrimidine nucleotide biosynthetic process 0.21434 small GTPase regulator activity 0.2144 positive regulation of small GTPase mediated signal transduction 0.21482 regulation of lyase activity 0.21624 lysosome organization 0.21725 negative regulation of axonogenesis 0.21737 detection of biotic stimulus 0.21749 cytokine binding 0.21755 calcium-dependent phospholipid binding 0.21766 sarcoplasmic reticulum membrane 0.21784 ribonucleoprotein complex assembly 0.21784 negative regulation of protein kinase cascade 0.2179 regulation of membrane potential 0.21826 protein heterooligomerization 0.21844 regulation of carbohydrate metabolic process 0.21891 regulation of leukocyte mediated immunity 0.21909 hydrolase activity, hydrolyzing O-glycosyl compounds 0.21909 activation of protein kinase A activity 0.21909 cholesterol metabolic process 0.21926 positive regulation of myeloid cell differentiation 0.21926 SNAP receptor activity 0.21932 response to radiation 0.21938 response to endogenous stimulus 0.21974 response to fungus 0.21998 cation homeostasis 0.22045 regulation of Ras protein signal transduction 0.22128 anion binding 0.22164 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 0.22199 skin development 0.22258 nucleobase, nucleoside and nucleotide biosynthetic process 0.2227 nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process 0.2227 fatty acid beta-oxidation 0.22276 regulation of immune system process 0.223 2'-deoxyribonucleotide metabolic process 0.22359 epithelial tube morphogenesis 0.22365 branching involved in ureteric bud morphogenesis 0.22365 phospholipase activity 0.22371 regulation of Rho protein signal transduction 0.2243 GTPase activator activity 0.22436 heme biosynthetic process 0.22442 detection of light stimulus 0.22442 regulation of myeloid leukocyte differentiation 0.22454 cellular response to protein stimulus 0.2246 cellular response to unfolded protein 0.2246 endoplasmic reticulum unfolded protein response 0.2246 telomeric DNA binding 0.22484 regulation of translation 0.22579 nucleus organization 0.22584 zinc ion transmembrane transporter activity 0.22584 oxygen binding 0.22596 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen 0.22602 transition metal ion transport 0.22614 vasodilation 0.22662 aldo-keto reductase activity 0.22667 negative regulation of lipid storage 0.22691 prostaglandin metabolic process 0.22697 prostanoid metabolic process 0.22697 vasoconstriction 0.22727 sugar binding 0.22839 response to hormone stimulus 0.22851 cell morphogenesis involved in differentiation 0.22857 I-kappaB kinase/NF-kappaB cascade 0.22863 recycling endosome 0.22952 homeostasis of number of cells 0.22976 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 0.23011 keratinocyte differentiation 0.23088 potassium channel activity 0.23112 histone methylation 0.23207 regulation of protein complex disassembly 0.23237 catecholamine metabolic process 0.23284 catechol metabolic process 0.23284 diol metabolic process 0.23284 mRNA transport 0.23296 purine nucleoside monophosphate biosynthetic process 0.23391 purine nucleoside monophosphate metabolic process 0.23391 purine ribonucleoside monophosphate biosynthetic process 0.23391 purine ribonucleoside monophosphate metabolic process 0.23391 secondary active transmembrane transporter activity 0.23432 translation factor activity, nucleic acid binding 0.23474 inorganic anion transport 0.23485 establishment of organelle localization 0.23491 voltage-gated sodium channel activity 0.23563 cell morphogenesis 0.23586 cell morphogenesis 0.23586 cell morphogenesis 0.23586 positive regulation of DNA binding 0.23604 skeletal system development 0.23646 G1 phase 0.23657 pore complex 0.23717 positive regulation of GTPase activity 0.23729 dephosphorylation 0.23734 integrin complex 0.23758 synaptic transmission, cholinergic 0.23811 cell projection morphogenesis 0.23883 regulation of Wnt receptor signaling pathway 0.23889 defense response to fungus 0.23906 ATP-dependent DNA helicase activity 0.23918 receptor signaling complex scaffold activity 0.2393 adult behavior 0.23936 neuron migration 0.23948 negative regulation of cell projection organization 0.2396 endoribonuclease activity 0.23977 central nervous system development 0.23977 regulation of interferon-gamma production 0.23989 regulation of transcription regulator activity 0.24031 regulation of transcription factor activity 0.24031 regulation of organ growth 0.24114 p53 binding 0.24138 cellular response to oxidative stress 0.24244 pattern specification process 0.24262 regulation of immunoglobulin production 0.24286 cytokine biosynthetic process 0.24321 mammary gland development 0.24363 RNA helicase activity 0.24375 neuron projection morphogenesis 0.24404 RNA-dependent ATPase activity 0.2441 transition metal ion transmembrane transporter activity 0.24458 actin filament bundle formation 0.24475 positive regulation of lymphocyte proliferation 0.24487 transcription factor complex 0.24511 adult walking behavior 0.24558 regulation of fat cell differentiation 0.2457 H4/H2A histone acetyltransferase complex 0.2457 positive regulation of hydrolase activity 0.24647 lysosomal membrane 0.24677 DNA alkylation 0.24736 DNA methylation 0.24736 membrane-enclosed lumen 0.24742 secondary active transmembrane transporter activity 0.24742 apoptosis 0.24772 positive regulation of JAK-STAT cascade 0.24784 actomyosin structure organization 0.24878 chemotaxis 0.24908 taxis 0.24908 telomere maintenance 0.24932 positive regulation of multicellular organismal process 0.2495 voltage-gated anion channel activity 0.24961 voltage-gated chloride channel activity 0.24961 RNA-dependent ATPase activity 0.24973 ATP-dependent RNA helicase activity 0.24973 negative regulation of cyclase activity 0.25021 negative regulation of adenylate cyclase activity 0.25021 negative regulation of lyase activity 0.25021 positive regulation of peptidase activity 0.25044 positive regulation of caspase activity 0.25044 glutamine metabolic process 0.25068 positive regulation of immune system process 0.25133 regulation of glucose transport 0.25139 regulation of cell shape 0.25145 organelle envelope lumen 0.25151 regulation of adenylate cyclase activity 0.25199 3'-5' exonuclease activity 0.2521 mitochondrial membrane 0.25228 actin filament-based process 0.25228 tube development 0.25234 positive regulation of nucleocytoplasmic transport 0.25234 mitochondrial inner membrane 0.25317 cell-substrate adhesion 0.25323 protein processing 0.25329 regulation of muscle organ development 0.25359 axonogenesis 0.25359 organelle inner membrane 0.25359 glutathione transferase activity 0.25376 BMP signaling pathway 0.25382 ion channel inhibitor activity 0.25394 channel inhibitor activity 0.25394 regulation of ossification 0.25424 tissue remodeling 0.2543 nucleotide kinase activity 0.25442 lipoprotein binding 0.25477 positive regulation of JUN kinase activity 0.25519 macromolecular complex remodeling 0.25525 protein-lipid complex remodeling 0.25525 plasma lipoprotein particle remodeling 0.25525 carbohydrate biosynthetic process 0.25531 heterogeneous nuclear ribonucleoprotein complex 0.25536 nuclear chromatin 0.25536 transferase activity, transferring glycosyl groups 0.25554 vitamin metabolic process 0.25572 sphingoid metabolic process 0.25602 regulation of coagulation 0.25625 positive regulation of B cell activation 0.25697 RNA splicing 0.25708 cytoskeleton-dependent intracellular transport 0.2575 cellular amide metabolic process 0.25845 cellular hormone metabolic process 0.25862 positive regulation of axonogenesis 0.25874 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 0.25886 negative regulation of transcription factor activity 0.25898 negative regulation of transcription regulator activity 0.25898 vitamin A metabolic process 0.2591 RNA polyadenylation 0.25928 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 0.2594 G2/M transition of mitotic cell cycle 0.25987 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 0.25993 RNA splicing, via transesterification reactions 0.25993 RNA splicing, via transesterification reactions 0.25993 nuclear mRNA splicing, via spliceosome 0.25993 protein serine/threonine kinase inhibitor activity 0.26011 peptide hormone binding 0.26046 L-glutamate transport 0.26123 acidic amino acid transport 0.26123 chromatin remodeling 0.26141 regulation of interleukin-2 production 0.26194 positive regulation of cell killing 0.26248 regulation of lipid storage 0.26266 extrinsic to plasma membrane 0.26301 gland development 0.26343 myosin filament 0.2636 humoral immune response 0.26366 protein amino acid dephosphorylation 0.26402 muscle cell differentiation 0.26443 endoribonuclease activity, producing 3'-phosphomonoesters 0.26461 chloride ion binding 0.26461 RNA splicing, via transesterification reactions 0.26491 neuropeptide receptor activity 0.26491 ARF guanyl-nucleotide exchange factor activity 0.26603 purine nucleotide metabolic process 0.26609 complement activation, classical pathway 0.26645 T cell differentiation in the thymus 0.26669 hemopoietic or lymphoid organ development 0.26704 regulation of interleukin-1 secretion 0.26704 leading edge membrane 0.26763 regulation of interleukin-8 production 0.26781 activation of JUN kinase activity 0.26846 positive regulation of mast cell proliferation 0.26852 positive regulation of B cell proliferation 0.26852 mitochondrial membrane part 0.269 regulation of calcium-mediated signaling 0.26935 MHC class I protein binding 0.26965 nucleotide-excision repair, DNA gap filling 0.26977 phototransduction 0.2703 regulation of body fluid levels 0.27048 chromosome condensation 0.27048 ligand-dependent nuclear receptor activity 0.27072 tumor necrosis factor receptor superfamily binding 0.27155 regulation of cyclic nucleotide biosynthetic process 0.27178 regulation of nucleotide biosynthetic process 0.27178 actin filament bundle 0.27214 stress fiber 0.27214 actin filament bundle 0.27214 actin filament bundle 0.27214 actin cytoskeleton organization 0.2722 inositol or phosphatidylinositol kinase activity 0.27273 vasculature development 0.27279 acetyltransferase activity 0.27297 regulation of production of molecular mediator of immune response 0.27303 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 0.27315 nuclear membrane 0.27362 morphogenesis of an epithelium 0.27398 non-membrane spanning protein tyrosine kinase activity 0.27421 nucleobase, nucleoside, nucleotide and nucleic acid transport 0.27451 Rho GTPase activator activity 0.27487 xenobiotic metabolic process 0.27493 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.27522 cellular polysaccharide metabolic process 0.27522 membrane invagination 0.27576 Ras GTPase binding 0.27605 calcium-dependent protein binding 0.27617 sphingolipid biosynthetic process 0.27635 sodium channel complex 0.27682 potassium ion transport 0.277 glycerolipid metabolic process 0.27718 mismatched DNA binding 0.27742 regulation of epidermis development 0.27759 molecular adaptor activity 0.27801 chromosome segregation 0.27913 response to pain 0.27979 cell motility 0.27979 regulation of ARF GTPase activity 0.28074 glycoprotein metabolic process 0.28174 transcription repressor activity 0.28216 inward rectifier potassium channel activity 0.28251 reproductive cellular process 0.28263 alkaloid metabolic process 0.28281 skeletal muscle tissue development 0.28287 protein targeting to membrane 0.28293 cytokine receptor activity 0.28305 monocarboxylic acid binding 0.28317 monocarboxylic acid transmembrane transporter activity 0.28328 spindle microtubule 0.28334 cytokine binding 0.2834 digestion 0.28358 histone binding 0.28435 Rho GTPase binding 0.28447 histone H2A acetylation 0.28459 palmitoyltransferase activity 0.28477 establishment or maintenance of cell polarity 0.28554 oxidoreductase activity, acting on peroxide as acceptor 0.28566 peroxidase activity 0.28566 polysaccharide biosynthetic process 0.28589 spliceosome assembly 0.28589 tetrapyrrole metabolic process 0.28648 porphyrin metabolic process 0.28648 fertilization 0.28684 carboxylic acid transmembrane transporter activity 0.2869 negative regulation of DNA binding 0.28696 steroid hormone receptor activity 0.28708 exopeptidase activity 0.28731 protein deacetylase activity 0.28749 histone deacetylase activity 0.28749 ER-associated protein catabolic process 0.28755 mesoderm development 0.28785 cellular amino acid catabolic process 0.28791 response to ionizing radiation 0.28797 membrane docking 0.28838 filopodium assembly 0.28856 cofactor biosynthetic process 0.28862 mRNA 3'-end processing 0.28897 positive regulation of organelle organization 0.28963 regulation of oxidoreductase activity 0.28969 regulation of cyclic nucleotide metabolic process 0.28992 L-amino acid transmembrane transporter activity 0.29052 organic acid:sodium symporter activity 0.29063 ossification 0.29075 second-messenger-mediated signaling 0.29081 cAMP-mediated signaling 0.29087 oxidoreductase activity, acting on the CH-CH group of donors 0.29105 proton-transporting two-sector ATPase complex, proton-transporting domain 0.29123 regulation of system process 0.29135 general RNA polymerase II transcription factor activity 0.29158 lymphocyte differentiation 0.29194 STAGA complex 0.29223 iron ion homeostasis 0.29259 chloride channel complex 0.29265 lipase activity 0.29277 neuropeptide binding 0.29277 regulation of myeloid cell differentiation 0.29289 regulation of actin filament-based process 0.29348 peptidyl-threonine phosphorylation 0.29389 regulation of multicellular organismal metabolic process 0.29401 regulation of nucleotide metabolic process 0.29413 regulation of blood coagulation 0.29449 nuclear pore 0.29455 transmembrane receptor protein phosphatase activity 0.29472 transmembrane receptor protein tyrosine phosphatase activity 0.29472 cell surface 0.2949 negative regulation of phosphorylation 0.29561 purine ribonucleoside metabolic process 0.29573 purine nucleoside metabolic process 0.29573 regulation of hydrolase activity 0.29597 energy derivation by oxidation of organic compounds 0.29603 small GTPase binding 0.29621 mitochondrial matrix 0.29638 purine nucleotide biosynthetic process 0.29656 lymphocyte proliferation 0.29662 negative regulation of transcription, DNA-dependent 0.29674 regulation of B cell activation 0.29727 DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis 0.29769 regulation of exit from mitosis 0.29793 regulation of nucleocytoplasmic transport 0.29828 positive regulation of interleukin-1 production 0.2984 isomerase activity 0.29852 hormone-mediated signaling pathway 0.29887 fat-soluble vitamin metabolic process 0.29976 negative regulation of protein metabolic process 0.30006 vacuole organization 0.30018 negative regulation of protein complex disassembly 0.30024 apoptotic mitochondrial changes 0.30024 receptor activator activity 0.30036 ribonucleotide catabolic process 0.30053 ribonucleoprotein complex biogenesis 0.30053 positive regulation of steroid metabolic process 0.30059 histone deacetylation 0.30178 cell-matrix adhesion 0.30207 transforming growth factor beta receptor, cytoplasmic mediator activity 0.30243 sterol homeostasis 0.30249 cholesterol homeostasis 0.30249 rRNA processing 0.30261 symporter activity 0.3029 positive regulation of phosphorus metabolic process 0.30296 positive regulation of phosphate metabolic process 0.30296 aminopeptidase activity 0.30314 protein heterodimerization activity 0.30314 regulation of caspase activity 0.30356 FMN binding 0.30362 water-soluble vitamin metabolic process 0.30379 ribonucleotide biosynthetic process 0.30415 oxidoreduction coenzyme metabolic process 0.30451 regulation of Ras GTPase activity 0.3051 regulation of protein complex assembly 0.30599 aromatic compound catabolic process 0.30622 monosaccharide catabolic process 0.30664 regulation of glial cell differentiation 0.30699 regulation of gliogenesis 0.30699 solute:sodium symporter activity 0.30711 pyridine nucleotide metabolic process 0.30723 regulation of ARF protein signal transduction 0.30777 glycerophospholipid biosynthetic process 0.30788 endoribonuclease activity, producing 5'-phosphomonoesters 0.30836 spindle 0.30943 antioxidant activity 0.30948 protein amino acid deacetylation 0.31014 immunoglobulin binding 0.31049 transcription elongation regulator activity 0.31067 myeloid cell differentiation 0.31108 cyclic-nucleotide-mediated signaling 0.31108 metalloendopeptidase activity 0.31144 organic acid transmembrane transporter activity 0.31162 clathrin coat 0.31203 recombinational repair 0.31203 double-strand break repair via homologous recombination 0.31203 ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism 0.31209 response to vitamin A 0.31251 regulation of blood vessel endothelial cell migration 0.31298 translation elongation factor activity 0.31328 lipid phosphorylation 0.31352 intrinsic to endoplasmic reticulum membrane 0.31363 activation of MAPK activity 0.31363 neurotransmitter transport 0.31393 receptor metabolic process 0.31452 cellular carbohydrate catabolic process 0.3147 extrinsic to membrane 0.31529 regulation of developmental growth 0.31547 cell projection organization 0.31577 4 iron, 4 sulfur cluster binding 0.31589 pyrimidine nucleoside metabolic process 0.3166 endothelial cell migration 0.31725 DNA helicase activity 0.31761 negative regulation of RNA metabolic process 0.31808 regulation of axonogenesis 0.31897 nucleic acid transport 0.31909 RNA transport 0.31909 establishment of RNA localization 0.31909 external side of plasma membrane 0.31944 post-Golgi vesicle-mediated transport 0.31956 nucleoid 0.31986 enzyme activator activity 0.31986 mitochondrial nucleoid 0.31986 positive regulation of protein modification process 0.3211 phenol metabolic process 0.3211 detection of chemical stimulus 0.32128 negative regulation of endothelial cell migration 0.32187 phosphatase activity 0.32211 negative regulation of myeloid leukocyte differentiation 0.32264 G-protein coupled amine receptor activity 0.32336 RNA catabolic process 0.32389 epidermis development 0.32472 phosphatase activity 0.32537 sensory organ development 0.32543 protein maturation by peptide bond cleavage 0.32561 regulation of translation 0.32614 embryonic pattern specification 0.32614 lipid homeostasis 0.32644 macromolecule methylation 0.32679 polysaccharide metabolic process 0.32679 NuA4 histone acetyltransferase complex 0.32679 positive regulation of cell projection organization 0.32709 amino sugar metabolic process 0.32721 carbohydrate transport 0.32845 glycosaminoglycan binding 0.3291 macromolecule localization 0.32988 positive regulation of gene-specific transcription from RNA polymerase II promoter 0.33005 endoplasmic reticulum lumen 0.33148 vacuole organization 0.33154 cellular response to nutrient levels 0.33201 positive regulation of MAP kinase activity 0.33248 detection of biotic stimulus 0.33266 lipid kinase activity 0.33302 purine ribonucleotide biosynthetic process 0.33308 membrane fusion 0.33402 DNA packaging 0.3342 glutamate signaling pathway 0.33432 regulation of actin cytoskeleton organization 0.33491 cell projection part 0.33539 tetrapyrrole biosynthetic process 0.33568 porphyrin biosynthetic process 0.33568 positive regulation of DNA repair 0.33592 positive regulation of cell cycle process 0.3361 cell division 0.33634 sulfur metabolic process 0.3364 pigment granule 0.33651 germ cell nucleus 0.33651 melanosome 0.33651 carbohydrate biosynthetic process 0.33675 retrograde transport, endosome to Golgi 0.33693 clathrin-coated vesicle 0.33758 lymphocyte differentiation 0.33764 glucose transport 0.33794 DNA regulatory region binding 0.33811 taste receptor activity 0.33835 regulation of cAMP biosynthetic process 0.33865 protein transmembrane transporter activity 0.33912 hexose catabolic process 0.34001 nuclear DNA-directed RNA polymerase complex 0.34007 DNA-directed RNA polymerase complex 0.34007 nuclear matrix 0.34019 cellular component biogenesis 0.34078 proton-transporting two-sector ATPase complex, catalytic domain 0.34114 regulation of mRNA processing 0.34132 sperm motility 0.34155 regulation of lipid biosynthetic process 0.34155 response to endoplasmic reticulum stress 0.34215 regulation of vasoconstriction 0.34238 heterocycle biosynthetic process 0.34244 cortical actin cytoskeleton organization 0.34333 interspecies interaction between organisms 0.34345 response to gamma radiation 0.34357 regulation of striated muscle tissue development 0.34357 endocytosis 0.34422 JAK-STAT cascade 0.34422 negative regulation of proteolysis 0.34529 positive regulation of protein transport 0.34659 cellular response to reactive oxygen species 0.3473 steroid metabolic process 0.34742 pattern binding 0.34748 polysaccharide binding 0.34748 positive regulation of phosphorylation 0.34778 fibroblast growth factor receptor signaling pathway 0.34843 activation of plasma proteins involved in acute inflammatory response 0.34908 negative regulation of MAP kinase activity 0.3492 chromosome, telomeric region 0.34944 plasma membrane 0.34991 sarcolemma 0.34991 enzyme inhibitor activity 0.35092 sodium channel activity 0.35104 steroid hydroxylase activity 0.35133 DNA replication 0.35258 hexose transport 0.35293 monosaccharide transport 0.35293 protein phosphatase regulator activity 0.35299 transcription factor TFIID complex 0.35471 regulation of cAMP metabolic process 0.35501 mRNA splice site selection 0.35548 acidic amino acid transmembrane transporter activity 0.35762 L-glutamate transmembrane transporter activity 0.35762 regulation of DNA metabolic process 0.35809 monovalent inorganic cation transport 0.35862 insulin-like growth factor binding 0.35922 RNA splicing 0.35969 calcium-independent cell-cell adhesion 0.36005 complement activation 0.36028 kinase activator activity 0.36111 beta-amyloid binding 0.36117 monoamine transport 0.36135 activation of immune response 0.3623 Golgi membrane 0.3623 cell-cell junction assembly 0.36248 vesicular fraction 0.36396 maintenance of protein location in cell 0.36408 hormone biosynthetic process 0.3642 nitric oxide mediated signal transduction 0.36455 positive regulation of T cell proliferation 0.36491 transferase activity, transferring sulfur-containing groups 0.36544 cell-cell junction organization 0.36615 T cell homeostasis 0.36639 regulation of exocytosis 0.36758 gluconeogenesis 0.36763 glutamate receptor activity 0.36781 embryonic digit morphogenesis 0.36817 promoter binding 0.36858 negative regulation of phosphorus metabolic process 0.36888 negative regulation of phosphate metabolic process 0.36888 antigen binding 0.369 regulation of microtubule cytoskeleton organization 0.36912 voltage-gated potassium channel activity 0.36959 positive regulation of mitosis 0.36995 positive regulation of nuclear division 0.36995 negative regulation of cell cycle process 0.37226 DNA modification 0.37279 cell-cell recognition 0.37285 SWI/SNF complex 0.37291 SWI/SNF-type complex 0.37291 neurotransmitter secretion 0.37303 myeloid leukocyte differentiation 0.37333 calcium-mediated signaling 0.37333 phosphoinositide-mediated signaling 0.37398 response to X-ray 0.37493 vesicle membrane 0.37499 insulin receptor binding 0.3751 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 0.37558 response to hydrogen peroxide 0.37576 androgen receptor binding 0.37587 cellular iron ion homeostasis 0.37599 positive regulation of synaptic transmission 0.37605 SH3/SH2 adaptor activity 0.37617 nucleoside triphosphate metabolic process 0.37653 retinoic acid receptor binding 0.37664 diterpenoid metabolic process 0.37676 retinoid metabolic process 0.37676 dopamine receptor signaling pathway 0.37884 condensed chromosome kinetochore 0.37902 kinetochore 0.37902 striated muscle contraction 0.37908 small GTPase mediated signal transduction 0.37961 L-amino acid transport 0.38068 terpenoid metabolic process 0.38085 nuclear chromosome part 0.38085 positive regulation of behavior 0.38127 organelle lumen 0.38151 nuclear export 0.38198 receptor regulator activity 0.38216 monosaccharide metabolic process 0.38222 response to UV 0.38222 vacuolar membrane 0.38228 regulation of GTPase activity 0.38239 positive regulation of cellular protein metabolic process 0.38257 cellular cation homeostasis 0.38305 antigen processing and presentation 0.38305 steroid biosynthetic process 0.38317 negative regulation of leukocyte proliferation 0.38364 negative regulation of lymphocyte proliferation 0.38364 negative regulation of mononuclear cell proliferation 0.38364 integral to organelle membrane 0.3837 fat cell differentiation 0.38376 protein amino acid alkylation 0.384 protein amino acid methylation 0.384 positive regulation of peptide secretion 0.38423 neuropeptide signaling pathway 0.38577 positive regulation of catabolic process 0.38595 beta-catenin binding 0.38637 detection of abiotic stimulus 0.38678 regulation of lymphocyte mediated immunity 0.38755 intestinal absorption 0.38797 coated pit 0.38797 mitotic cell cycle checkpoint 0.38844 memory 0.38844 striated muscle tissue development 0.3885 sex determination 0.38892 RNA export from nucleus 0.38921 cofactor metabolic process 0.38927 cytoplasmic mRNA processing body 0.38951 integral to membrane of membrane fraction 0.38957 nuclear-transcribed mRNA catabolic process 0.38963 hexose metabolic process 0.38969 actomyosin 0.38986 extrinsic to plasma membrane 0.39022 glycosylation 0.3904 macromolecule glycosylation 0.3904 protein amino acid glycosylation 0.3904 ncRNA processing 0.3904 sperm-egg recognition 0.39057 binding of sperm to zona pellucida 0.39057 negative regulation of immune response 0.39063 carboxypeptidase activity 0.39123 regulation of microtubule polymerization or depolymerization 0.39135 microtubule bundle formation 0.39146 regulation of vesicle-mediated transport 0.39164 positive regulation of protein amino acid phosphorylation 0.39194 membrane depolarization 0.39312 response to extracellular stimulus 0.39318 oxidoreductase activity, acting on the aldehyde or oxo group of donors 0.39419 voltage-gated calcium channel complex 0.39478 defense response to virus 0.39484 cellular amino acid metabolic process 0.3952 regulation of epithelial cell differentiation 0.39532 negative regulation of protein amino acid phosphorylation 0.39555 transcription initiation 0.39609 calcium ion-dependent exocytosis 0.39609 ncRNA metabolic process 0.39615 establishment or maintenance of cell polarity 0.3965 establishment or maintenance of cell polarity 0.3965 membrane lipid biosynthetic process 0.3965 ion channel complex 0.39698 metal ion transmembrane transporter activity 0.39721 glycerol ether metabolic process 0.39733 gamma-aminobutyric acid signaling pathway 0.39787 sulfur amino acid biosynthetic process 0.39846 histone ubiquitination 0.39858 chromatin modification 0.39864 RNA polymerase complex 0.39893 Ras GTPase activator activity 0.39917 deoxyribonucleotide catabolic process 0.39947 copper ion binding 0.40101 nuclear transport 0.40107 coenzyme biosynthetic process 0.40124 positive regulation of transcription regulator activity 0.40154 positive regulation of transcription factor activity 0.40154 vesicle lumen 0.40196 cytoplasmic membrane-bounded vesicle lumen 0.40196 cell adhesion molecule binding 0.40213 positive regulation of cytoskeleton organization 0.40225 endocytic vesicle 0.40243 regulation of neurotransmitter secretion 0.40273 phosphoinositide metabolic process 0.40285 cation channel activity 0.40397 regulation of interleukin-1 beta production 0.40427 cation channel activity 0.40427 cation channel activity 0.40427 positive regulation of response to stimulus 0.40462 acute-phase response 0.40468 anion transport 0.40599 growth factor receptor binding 0.40611 detection of visible light 0.40611 insulin-like growth factor receptor binding 0.4067 organelle localization 0.40699 regulation of behavior 0.40735 regulation of natural killer cell mediated immunity 0.40806 regulation of natural killer cell mediated immunity 0.40806 regulation of natural killer cell mediated cytotoxicity 0.40806 one-carbon metabolic process 0.4083 SH2 domain binding 0.40854 nuclear speck 0.4099 Wnt receptor signaling pathway through beta-catenin 0.41002 transcription initiation from RNA polymerase II promoter 0.41025 spindle assembly 0.41067 epithelial to mesenchymal transition 0.41108 secretion by cell 0.41191 response to toxin 0.41221 cofactor transporter activity 0.41363 synaptic transmission 0.41399 learning 0.41458 perinuclear region of cytoplasm 0.41494 oxidoreductase activity, acting on heme group of donors, oxygen as acceptor 0.41506 oxidoreductase activity, acting on heme group of donors 0.41506 cytochrome-c oxidase activity 0.41506 heme-copper terminal oxidase activity 0.41506 dendritic spine 0.41529 gene silencing 0.41553 filopodium 0.41577 ribonucleotide metabolic process 0.41642 ribonucleotide metabolic process 0.41642 regulation of immunoglobulin mediated immune response 0.41695 regulation of B cell mediated immunity 0.41695 ubiquitin binding 0.41761 small conjugating protein binding 0.41761 protein N-terminus binding 0.41784 nucleocytoplasmic transport 0.41915 tRNA binding 0.41915 protein kinase C activity 0.42009 protein secretion 0.42253 regulation of viral genome replication 0.4227 regulation of epithelial cell proliferation 0.42336 glucose catabolic process 0.42407 cellular response to starvation 0.42442 monoamine transport 0.42555 vesicle organization 0.42573 mRNA catabolic process 0.42638 regulation of endothelial cell migration 0.42667 negative regulation of transforming growth factor beta receptor signaling pathway 0.42733 low-density lipoprotein particle 0.42822 regulation of mitotic cell cycle 0.42916 nuclear body 0.42988 chloride transport 0.43082 transmembrane transport 0.43088 regulation of circadian rhythm 0.43118 voltage-gated channel activity 0.4313 voltage-gated ion channel activity 0.4313 phosphoinositide phosphorylation 0.43136 response to unfolded protein 0.43177 voltage-gated potassium channel complex 0.43189 potassium channel complex 0.43189 apical plasma membrane 0.43231 voltage-gated cation channel activity 0.43237 T cell differentiation 0.4326 T cell differentiation 0.4326 positive regulation of phospholipase C activity 0.43355 activation of phospholipase C activity 0.43355 response to starvation 0.43426 cell cycle checkpoint 0.43432 muscle myosin complex 0.43438 septin complex 0.4345 protein homotetramerization 0.43509 peptidyl-serine phosphorylation 0.43515 chromatin assembly or disassembly 0.43515 1-phosphatidylinositol-3-kinase activity 0.43592 regulation of actin filament length 0.43723 cation-transporting ATPase activity 0.43758 DNA replication initiation 0.43764 positive regulation of Ras protein signal transduction 0.43794 response to nutrient 0.43847 gated channel activity 0.43871 phospholipid biosynthetic process 0.4393 hormone secretion 0.43936 negative regulation of leukocyte activation 0.44043 pattern recognition receptor activity 0.44084 apoptotic protease activator activity 0.44138 positive regulation of protein metabolic process 0.44138 retinoic acid receptor activity 0.44155 transferase activity, transferring alkyl or aryl (other than methyl) groups 0.44256 mRNA processing 0.44345 G-protein signaling, coupled to cAMP nucleotide second messenger 0.44392 intracellular organelle lumen 0.4441 platelet alpha granule lumen 0.44481 positive regulation of lipase activity 0.44541 response to mechanical stimulus 0.44541 cartilage development 0.44576 large ribosomal subunit 0.44588 vesicle docking 0.44594 cell cortex part 0.446 acyl-CoA dehydrogenase activity 0.44641 organic cation transmembrane transporter activity 0.44707 oxygen and reactive oxygen species metabolic process 0.44724 cellular response to extracellular stimulus 0.4473 cellular response to external stimulus 0.4473 phosphatidylinositol metabolic process 0.44748 kinetochore 0.44772 maintenance of protein location 0.44878 positive regulation of inflammatory response 0.45015 coated vesicle 0.45015 cation channel complex 0.4505 regulation of receptor activity 0.4508 negative regulation of DNA replication 0.45122 DNA unwinding during replication 0.45157 anion exchanger activity 0.45175 inorganic anion exchanger activity 0.45175 intrinsic to organelle membrane 0.45205 cortical actin cytoskeleton 0.4521 G-protein signaling, coupled to cyclic nucleotide second messenger 0.45258 retrograde vesicle-mediated transport, Golgi to ER 0.45282 tropomyosin binding 0.45323 muscle fiber development 0.45335 regulation of neuron projection development 0.45359 cellular response to biotic stimulus 0.4537 positive regulation of nitric oxide biosynthetic process 0.45394 sphingolipid metabolic process 0.45394 receptor signaling protein tyrosine kinase activity 0.45536 activation of protein kinase activity 0.45697 preassembly of GPI anchor in ER membrane 0.45714 lipid oxidation 0.45779 fatty acid oxidation 0.45779 hexosaminidase activity 0.45785 regulation of MAP kinase activity 0.45803 cilium 0.45862 learning or memory 0.4588 clathrin coat 0.45886 double-strand break repair 0.45886 innate immune response 0.45963 purine ribonucleotide metabolic process 0.46052 organelle fission 0.4623 positive regulation of MAPKKK cascade 0.46242 microtubule basal body 0.46426 regulation of lipase activity 0.46443 ovarian follicle development 0.46443 heparin binding 0.46455 mitosis 0.46455 nuclear division 0.46455 regulation of endocytosis 0.46461 regulation of protein secretion 0.46526 sulfotransferase activity 0.46532 transferase activity, transferring alkyl or aryl (other than methyl) groups 0.46538 organic anion transmembrane transporter activity 0.46562 axis specification 0.46651 regulation of the force of heart contraction 0.46793 regulation of endopeptidase activity 0.46811 structural constituent of eye lens 0.46882 cytoplasmic vesicle part 0.46935 mediator complex 0.47001 regulation of phospholipase activity 0.47007 alcohol biosynthetic process 0.4703 phosphoinositide 3-kinase complex 0.47048 protein ubiquitination 0.47113 hindbrain development 0.47119 negative regulation of immune system process 0.47137 sulfate transport 0.47143 cell cycle phase 0.4719 glycolysis 0.47196 response to retinoic acid 0.47196 molting cycle 0.47196 positive regulation of protein ubiquitination 0.47261 regulation of acute inflammatory response 0.47297 heat shock protein binding 0.47374 lymphocyte homeostasis 0.47404 protein export from nucleus 0.47457 embryonic limb morphogenesis 0.47463 embryonic appendage morphogenesis 0.47463 small nuclear ribonucleoprotein complex 0.47469 amine binding 0.47558 sensory perception of taste 0.47587 neurogenesis 0.47599 nicotinamide metabolic process 0.47647 nicotinamide nucleotide metabolic process 0.47647 regulation of gene expression, epigenetic 0.47742 negative regulation of response to stimulus 0.47759 cellular protein complex assembly 0.47765 intramolecular oxidoreductase activity 0.47801 peroxisome 0.4789 manganese ion binding 0.47931 regulation of G-protein coupled receptor protein signaling pathway 0.47937 positive regulation of phospholipase activity 0.47943 spindle pole 0.47991 ARF GTPase activator activity 0.48151 gas transport 0.48174 cortical cytoskeleton 0.48174 thyroid hormone receptor binding 0.48192 metal ion homeostasis 0.48257 syntaxin binding 0.48269 bile acid metabolic process 0.48305 regulation of cytokine production 0.48311 leukocyte homeostasis 0.48328 synaptic vesicle 0.484 leukocyte mediated immunity 0.48417 leukocyte mediated immunity 0.48417 leukocyte mediated immunity 0.48417 regulation of transcription factor import into nucleus 0.48471 dendrite 0.485 protein kinase regulator activity 0.48554 female gamete generation 0.48583 regulation of cellular response to stress 0.48589 response to nicotine 0.48654 regulation of cell projection organization 0.48761 negative regulation of ossification 0.48969 regulation of cytoskeleton organization 0.49087 exonuclease activity 0.49117 protein modification by small protein conjugation 0.49158 immune response-regulating cell surface receptor signaling pathway 0.49164 immune response-activating cell surface receptor signaling pathway 0.49164 protein deubiquitination 0.49223 embryonic axis specification 0.49265 membrane organization 0.49295 blood vessel development 0.49318 triglyceride metabolic process 0.49336 negative regulation of lipid transport 0.49354 drug metabolic process 0.49389 cofactor catabolic process 0.49413 negative regulation of cytoskeleton organization 0.49472 DNA damage response, signal transduction 0.49496 regulation of actin polymerization or depolymerization 0.4952 coated vesicle 0.49603 epithelial cell differentiation 0.49692 estrogen receptor signaling pathway 0.49757 peptidyl-prolyl cis-trans isomerase activity 0.49781 purine NTP-dependent helicase activity 0.49804 ATP-dependent helicase activity 0.49804 transmembrane receptor protein serine/threonine kinase signaling protein activity 0.49804 membrane lipid metabolic process 0.49846 lipoprotein particle clearance 0.49917 histone H4 acetylation 0.49976 chromatin binding 0.50018 phosphatase binding 0.50053 negative regulation of protein catabolic process 0.50059 cellular response to chemical stimulus 0.50089 proteoglycan metabolic process 0.50119 positive regulation of NF-kappaB transcription factor activity 0.5016 DNA duplex unwinding 0.50249 DNA geometric change 0.50249 microbody 0.5029 snRNA metabolic process 0.50391 snRNA processing 0.50391 integrator complex 0.50391 proton-transporting ATPase activity, rotational mechanism 0.50445 phosphatidylcholine metabolic process 0.50504 calcium ion transport 0.5051 neuron projection development 0.50729 interleukin-1 receptor binding 0.50759 retinol binding 0.50943 microtubule cytoskeleton organization 0.50978 response to temperature stimulus 0.51025 positive regulation of immune response 0.51037 negative regulation of catabolic process 0.51085 acute inflammatory response 0.51334 neuromuscular synaptic transmission 0.51446 hair follicle morphogenesis 0.51506 Golgi apparatus part 0.51553 myosin II complex 0.51589 ectoderm development 0.51624 ionotropic glutamate receptor activity 0.51672 hormone binding 0.5179 regulation of DNA binding 0.51808 positive regulation of ligase activity 0.51832 cAMP-dependent protein kinase regulator activity 0.51844 sensory perception of pain 0.51855 organic ether metabolic process 0.51891 protein kinase inhibitor activity 0.51897 ADP binding 0.52033 regulation of Rab GTPase activity 0.52253 Rab GTPase activator activity 0.52253 pyrimidine ribonucleoside metabolic process 0.52258 nucleocytoplasmic transport 0.5227 maintenance of location in cell 0.52276 cellular biogenic amine catabolic process 0.52288 divalent metal ion transport 0.52318 eukaryotic translation initiation factor 3 complex 0.52353 innate immune response 0.52359 protein-hormone receptor activity 0.52383 regulation of osteoblast differentiation 0.52448 calcium ion transmembrane transporter activity 0.52478 actin binding 0.52667 collagen metabolic process 0.52673 mannosyltransferase activity 0.52673 ATPase activity 0.52691 cytoplasmic vesicle membrane 0.52697 insulin secretion 0.52792 protein amino acid acetylation 0.52816 GABA receptor activity 0.52822 sulfuric ester hydrolase activity 0.53189 chromatin 0.53195 coenzyme metabolic process 0.53213 regulation of response to biotic stimulus 0.53278 ATPase activity, coupled 0.53343 phosphoinositide 3-kinase activity 0.53367 transcription corepressor activity 0.53586 cellular metal ion homeostasis 0.5361 regulation of S phase 0.53669 regulation of embryonic development 0.53729 protein folding 0.5374 ribosome biogenesis 0.53746 nervous system development 0.53806 ligand-gated ion channel activity 0.53811 ligand-gated channel activity 0.53811 hydrolase activity, acting on glycosyl bonds 0.53859 axonemal dynein complex 0.54001 FAD binding 0.54049 heterotrimeric G-protein complex 0.54066 acyl-CoA binding 0.54108 actin cytoskeleton reorganization 0.54197 regulation of ligase activity 0.54203 regulation of intracellular pH 0.54209 male germ cell nucleus 0.54345 peptide secretion 0.54493 peptide hormone secretion 0.54493 microsome 0.54547 positive regulation of ubiquitin-protein ligase activity 0.54576 secondary metabolic process 0.54582 ubiquitin protein ligase binding 0.54594 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 0.54653 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.54754 elevation of cytosolic calcium ion concentration 0.54795 protein modification by small protein removal 0.54873 camera-type eye development 0.54873 eye development 0.54873 inhibition of adenylate cyclase activity by G-protein signaling pathway 0.54908 regulation of survival gene product expression 0.54932 serine-type endopeptidase activity 0.54985 regulation of peptide secretion 0.5505 regulation of peptide transport 0.5505 response to metal ion 0.5508 phosphate transmembrane transporter activity 0.5511 retinal binding 0.55116 postsynaptic density 0.5521 complement activation, alternative pathway 0.55264 localization 0.55317 regulation of peptidase activity 0.55525 lymphocyte activation during immune response 0.55614 activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger 0.55631 intramolecular oxidoreductase activity, transposing C=C bonds 0.55744 copper ion transport 0.55821 RNA methyltransferase activity 0.55898 calcium ion transport into cytosol 0.55904 anion transport 0.55922 regionalization 0.55922 acylglycerol metabolic process 0.55945 neutral lipid metabolic process 0.55945 early endosome 0.56023 endosome transport 0.56064 extracellular-glutamate-gated ion channel activity 0.56064 negative regulation of translation 0.56082 transcriptional repressor complex 0.56165 peptidyl-tyrosine phosphorylation 0.56189 specific RNA polymerase II transcription factor activity 0.56189 negative regulation of cellular protein metabolic process 0.56283 regulation of cytokine secretion 0.56432 structure-specific DNA binding 0.56461 regulation of ubiquitin-protein ligase activity 0.56526 cerebral cortex development 0.56598 high-density lipoprotein particle 0.56977 tRNA aminoacylation for protein translation 0.57001 amino acid activation 0.57001 tRNA aminoacylation 0.57001 localization within membrane 0.57202 cell soma 0.57244 cholesterol binding 0.57291 brush border 0.57297 helicase activity 0.5735 neurotransmitter binding 0.57659 regulation of epidermal growth factor receptor signaling pathway 0.57659 calcium-dependent cell-cell adhesion 0.5773 cellular response to hormone stimulus 0.57777 cellular response to endogenous stimulus 0.57777 response to fungus 0.58151 ATP biosynthetic process 0.58216 ATP synthesis coupled proton transport 0.58216 energy coupled proton transport, down electrochemical gradient 0.58216 solute:hydrogen symporter activity 0.58275 negative regulation of cell proliferation 0.5837 cysteine-type endopeptidase activity 0.58388 regulation of ubiquitin-protein ligase activity during mitotic cell cycle 0.58429 antigen receptor-mediated signaling pathway 0.58435 regulation of stress-activated protein kinase signaling pathway 0.58465 negative regulation of transcription factor import into nucleus 0.58488 ciliary or flagellar motility 0.58536 protein targeting to mitochondrion 0.58577 nuclear chromosome 0.58607 alditol metabolic process 0.58648 inner ear morphogenesis 0.5866 cell redox homeostasis 0.58678 positive regulation of proteolysis 0.58702 centrosome 0.5872 regulation of defense response to virus 0.58856 positive regulation of calcium ion transport 0.5888 gene silencing by RNA 0.59093 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors 0.59158 respiratory gaseous exchange 0.5917 small conjugating protein ligase activity 0.59194 activation of NF-kappaB-inducing kinase activity 0.59218 polypeptide N-acetylgalactosaminyltransferase activity 0.59277 regulation of proteolysis 0.59277 cell projection assembly 0.59336 vitamin transport 0.5936 cell projection membrane 0.59389 ligand-dependent nuclear receptor transcription coactivator activity 0.59407 acid-amino acid ligase activity 0.59467 spindle organization 0.59467 proteasome complex 0.59561 C-acyltransferase activity 0.59567 acetyl-CoA metabolic process 0.59668 multicellular organismal macromolecule metabolic process 0.59674 N-acyltransferase activity 0.59698 nucleotide-sugar metabolic process 0.59763 ATPase activity 0.59881 neurotransmitter receptor activity 0.6 ATPase activity, coupled to transmembrane movement of ions 0.6003 di-, tri-valent inorganic cation homeostasis 0.60047 aspartate family amino acid metabolic process 0.60083 ligase activity, forming aminoacyl-tRNA and related compounds 0.60136 ligase activity, forming carbon-oxygen bonds 0.60136 aminoacyl-tRNA ligase activity 0.60136 ubiquitin-dependent protein catabolic process 0.60136 dendrite development 0.60231 cis-trans isomerase activity 0.60237 glucuronosyltransferase activity 0.60273 coreceptor activity 0.6029 leukocyte proliferation 0.60302 mononuclear cell proliferation 0.60302 adenylate cyclase activity 0.60326 protein targeting to peroxisome 0.60409 B cell differentiation 0.60433 acetylglucosaminyltransferase activity 0.60468 regulation of hormone secretion 0.6051 microfilament motor activity 0.60694 response to inorganic substance 0.60777 regulation of cellular localization 0.60836 SAGA-type complex 0.6086 organic anion transport 0.60907 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process 0.60913 nuclear outer membrane 0.60919 lipase inhibitor activity 0.61014 leukocyte migration 0.61031 regulation of insulin secretion 0.61085 regulation of glucose metabolic process 0.61108 peptidyl-amino acid modification 0.61197 protein transporter activity 0.61304 calcium channel activity 0.61494 regulation of endothelial cell proliferation 0.61642 positive regulation of lyase activity 0.61654 signal sequence binding 0.61695 transcription from RNA polymerase II promoter 0.61695 small conjugating protein ligase activity 0.61701 small conjugating protein ligase activity 0.61701 cellular di-, tri-valent inorganic cation homeostasis 0.61808 G2/M transition checkpoint 0.61814 establishment of cell polarity 0.61844 cytokine receptor activity 0.61926 regulation of peptidyl-serine phosphorylation 0.61938 sodium ion transport 0.61968 regulation of synaptic transmission 0.61968 ER to Golgi vesicle-mediated transport 0.6198 endosome organization 0.61998 neuropeptide hormone activity 0.62021 regulation of JNK cascade 0.62051 filamentous actin 0.62069 phospholipid metabolic process 0.62069 metalloexopeptidase activity 0.62075 cortical cytoskeleton organization 0.62087 positive regulation of stress-activated protein kinase signaling pathway 0.62134 vesicle docking during exocytosis 0.62158 nuclear envelope 0.62164 histone acetylation 0.6217 negative regulation of protein modification process 0.62199 circadian rhythm 0.6243 multicellular organismal metabolic process 0.62472 ubiquitin-protein ligase activity 0.62507 cartilage condensation 0.62549 protein amino acid lipidation 0.6259 ligase activity, forming carbon-nitrogen bonds 0.6262 transcription elongation factor complex 0.62768 NLS-bearing substrate import into nucleus 0.62816 peptide metabolic process 0.62816 ribosome 0.62828 aspartate family amino acid biosynthetic process 0.62893 acid secretion 0.6291 embryonic skeletal system morphogenesis 0.6294 membrane raft 0.63029 myosin complex 0.63041 MHC protein complex 0.63065 cytoplasmic microtubule 0.63148 regulation of neurological system process 0.63219 sulfur compound biosynthetic process 0.63237 DNA helicase activity 0.63242 negative regulation of protein polymerization 0.63266 peptidyl-threonine modification 0.63284 rRNA binding 0.63302 condensed nuclear chromosome 0.63361 negative regulation of protein secretion 0.63373 DNA conformation change 0.63385 cell-cell junction 0.63432 AP-type membrane coat adaptor complex 0.63474 brown fat cell differentiation 0.63491 Wnt receptor signaling pathway 0.63545 sulfur amino acid metabolic process 0.63563 chromosome, centromeric region 0.63592 organelle fusion 0.63604 scavenger receptor activity 0.63604 endoplasmic reticulum membrane 0.63711 lipopolysaccharide binding 0.63734 cytokine production 0.6374 protein binding, bridging 0.63764 phosphatidylinositol phosphate kinase activity 0.63811 positive regulation of neurological system process 0.63883 microtubule cytoskeleton 0.63942 hormone metabolic process 0.63948 negative regulation of ubiquitin-protein ligase activity 0.63995 negative regulation of ligase activity 0.63995 nucleosome assembly 0.64025 glycerol metabolic process 0.64049 anion exchanger activity 0.64049 regulation of protein polymerization 0.64066 gastrulation with mouth forming second 0.64072 steroid hormone receptor signaling pathway 0.64114 negative regulation of protein transport 0.64143 transport vesicle 0.64185 protein modification by small protein conjugation or removal 0.64203 serine-type peptidase activity 0.64303 serine hydrolase activity 0.64309 isoprenoid biosynthetic process 0.64327 histone methyltransferase complex 0.64333 methyltransferase complex 0.64333 cilium assembly 0.64392 monosaccharide biosynthetic process 0.64422 microtubule-based movement 0.64452 anion:anion antiporter activity 0.64481 purine nucleoside triphosphate biosynthetic process 0.64541 purine ribonucleoside triphosphate biosynthetic process 0.64541 cAMP binding 0.64552 positive regulation of protein secretion 0.64772 contractile fiber 0.64778 DNA-dependent ATPase activity 0.64778 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 0.64801 chromatin remodeling complex 0.64813 positive regulation of cyclase activity 0.64932 activation of adenylate cyclase activity 0.64967 DNA-directed DNA polymerase activity 0.65181 positive regulation of defense response 0.65199 calmodulin-dependent protein kinase activity 0.65216 protein amino acid acylation 0.6524 chylomicron 0.65252 positive regulation of glucose transport 0.65287 positive regulation of glucose import 0.65287 cardiac muscle contraction 0.65311 polyol metabolic process 0.6537 membrane coat 0.65406 regulation of transmission of nerve impulse 0.65525 pteridine and derivative metabolic process 0.6556 pteridine and derivative metabolic process 0.6556 hormone transport 0.6559 histone deubiquitination 0.65637 regulation of mitosis 0.65661 regulation of nuclear division 0.65661 developmental growth 0.65691 hair cycle process 0.65732 molting cycle process 0.65732 nuclear import 0.65892 chromatin remodeling complex 0.65922 activation of caspase activity 0.65963 steroid dehydrogenase activity 0.66034 transcription activator activity 0.6607 transcription coactivator activity 0.6607 histone H3 acetylation 0.66123 small nucleolar ribonucleoprotein complex 0.66147 immune effector process 0.66177 regulation of defense response 0.66183 regulation of nitric oxide biosynthetic process 0.66189 endosomal part 0.662 transferase activity, transferring nitrogenous groups 0.66218 protein phosphatase type 2A regulator activity 0.66248 mitochondrial small ribosomal subunit 0.66289 organellar small ribosomal subunit 0.66289 regulation of intracellular transport 0.66301 translation regulator activity 0.66366 N-methyltransferase activity 0.66378 DNA N-glycosylase activity 0.66396 coenzyme catabolic process 0.66497 protein localization 0.66503 peroxisomal transport 0.66532 ATP biosynthetic process 0.66538 negative regulation of T cell proliferation 0.66686 response to osmotic stress 0.66704 positive regulation of protein polymerization 0.66852 carbohydrate transport 0.66918 carbohydrate transport 0.66918 peptide binding 0.66918 protein stabilization 0.67007 regulation of striated muscle contraction 0.67042 tRNA-specific ribonuclease activity 0.67095 negative regulation of oxidoreductase activity 0.67107 regulation of cellular pH 0.67155 phospholipase A2 activity 0.67161 segmentation 0.67279 regulation of cell cycle process 0.67303 RNA polymerase II transcription factor activity 0.67309 proteasomal protein catabolic process 0.67427 proteasomal ubiquitin-dependent protein catabolic process 0.67427 regulation of DNA recombination 0.67427 Rab GTPase binding 0.67564 hexose biosynthetic process 0.67587 serotonin receptor activity 0.67647 tRNA metabolic process 0.67676 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 0.67688 aging 0.67724 cytosolic calcium ion transport 0.67759 proton-transporting two-sector ATPase complex 0.67771 protein-DNA complex assembly 0.67836 response to molecule of bacterial origin 0.67848 motor activity 0.67937 regulation of hormone levels 0.67996 synapse part 0.68121 protein C-terminus binding 0.68151 nucleoside triphosphate biosynthetic process 0.68222 ribonucleoside triphosphate biosynthetic process 0.68222 intracellular receptor-mediated signaling pathway 0.68234 positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle 0.68257 visual behavior 0.68364 positive regulation of smooth muscle cell proliferation 0.68382 regulation of S phase of mitotic cell cycle 0.68382 regulation of cell killing 0.68388 proximal/distal pattern formation 0.68405 protein transporter activity 0.68524 positive regulation of JNK cascade 0.68577 phosphatase inhibitor activity 0.68672 quinone cofactor metabolic process 0.68702 lipid particle 0.6882 cellular calcium ion homeostasis 0.68886 regulation of mitotic metaphase/anaphase transition 0.68903 regulation of interleukin-2 biosynthetic process 0.68957 endosome membrane 0.6898 organophosphate metabolic process 0.69057 response to protein stimulus 0.69235 cytosolic calcium ion homeostasis 0.69253 negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle 0.69259 synapse 0.69318 GTP metabolic process 0.69348 positive regulation of epithelial cell proliferation 0.69389 protein polymerization 0.69443 negative regulation of protein complex assembly 0.69478 regulation of cell size 0.69549 maintenance of location 0.69721 DNA damage checkpoint 0.69781 proteasome core complex 0.69834 histone acetyltransferase complex 0.69846 positive regulation of cell growth 0.69858 peptidyl-tyrosine modification 0.69881 regulation of interleukin-6 production 0.69905 nicotinic acetylcholine-gated receptor-channel complex 0.69917 regulation of response to external stimulus 0.69935 peptide receptor activity, G-protein coupled 0.69964 peptide receptor activity 0.69964 cellular component assembly involved in morphogenesis 0.70036 transaminase activity 0.70089 negative regulation of cellular component organization 0.70089 sensory perception of light stimulus 0.70095 visual perception 0.70095 regulation of protein transport 0.7032 response to light stimulus 0.70403 negative regulation of protein kinase activity 0.70545 chromatin silencing 0.70551 sterol binding 0.70557 cytosolic small ribosomal subunit 0.70557 regulation of muscle contraction 0.70611 high-density lipoprotein particle remodeling 0.7064 cellular response to hydrogen peroxide 0.70676 branched chain family amino acid metabolic process 0.70676 positive regulation of natural killer cell mediated immunity 0.70723 positive regulation of natural killer cell mediated immunity 0.70723 positive regulation of natural killer cell mediated cytotoxicity 0.70723 acetylgalactosaminyltransferase activity 0.70735 RNA polymerase II transcription mediator activity 0.70759 general RNA polymerase II transcription factor activity 0.70759 isoprenoid binding 0.70836 retinoid binding 0.70836 protein folding 0.70854 protein folding 0.70854 protein folding 0.70854 purine nucleoside triphosphate metabolic process 0.71008 structural constituent of muscle 0.71043 protein serine/threonine phosphatase activity 0.71067 negative regulation of macrophage derived foam cell differentiation 0.71132 protein complex disassembly 0.71138 cellular protein complex disassembly 0.71138 excretion 0.71162 cysteine-type peptidase activity 0.71215 kinase inhibitor activity 0.71334 primary active transmembrane transporter activity 0.71363 P-P-bond-hydrolysis-driven transmembrane transporter activity 0.71363 activation of MAPKK activity 0.71375 positive regulation of adenylate cyclase activity 0.71541 histone-lysine N-methyltransferase activity 0.71695 lysine N-methyltransferase activity 0.71695 protein-lysine N-methyltransferase activity 0.71695 phosphatidylinositol binding 0.71737 DNA repair 0.7182 response to antibiotic 0.71832 regulation of catabolic process 0.71855 negative regulation of B cell activation 0.71909 regulation of calcium ion transport into cytosol 0.7198 regulation of microtubule-based process 0.72004 phosphoprotein binding 0.72057 cellular respiration 0.72075 autophagy 0.72092 regulation of immune response 0.72146 clathrin adaptor complex 0.72146 mitochondrion organization 0.72164 ruffle 0.72353 positive regulation of secretion 0.72407 beta-tubulin binding 0.72478 RNA polymerase II carboxy-terminal domain kinase activity 0.72507 reproductive developmental process 0.72507 leukocyte adhesion 0.72549 regulation of adenylate cyclase activity involved in G-protein signaling pathway 0.7265 positive regulation of adenylate cyclase activity by G-protein signaling pathway 0.7265 activation of adenylate cyclase activity by G-protein signaling pathway 0.7265 dynein complex 0.72662 cobalt ion binding 0.72697 regulation of interleukin-6 biosynthetic process 0.72721 carbohydrate catabolic process 0.72733 carbohydrate catabolic process 0.72733 eye development 0.72893 calcium ion homeostasis 0.73076 appendage morphogenesis 0.73112 limb morphogenesis 0.73112 sterol transporter activity 0.73402 nucleosome 0.73402 integral to endoplasmic reticulum membrane 0.73456 protein import into nucleus, docking 0.73557 GABA-A receptor activity 0.73563 structural constituent of ribosome 0.7358 cellular response to organic substance 0.73622 monosaccharide binding 0.73746 T cell receptor complex 0.73764 cell cortex 0.73853 ubiquitin thiolesterase activity 0.73918 negative regulation of lymphocyte activation 0.73948 calcium channel complex 0.73983 cytosolic large ribosomal subunit 0.74108 basal plasma membrane 0.74126 protein-lipid complex 0.74132 plasma lipoprotein particle 0.74132 voltage-gated calcium channel activity 0.74138 regulation of immune effector process 0.74191 protein deubiquitination 0.74215 microtubule motor activity 0.74315 tubulin-tyrosine ligase activity 0.74392 monocarboxylic acid transmembrane transporter activity 0.74434 regulation of macrophage derived foam cell differentiation 0.74458 internal side of plasma membrane 0.74458 transferase activity, transferring hexosyl groups 0.74475 defense response to bacterium 0.74547 visual learning 0.74552 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 0.74594 axon 0.74671 negative regulation of blood coagulation 0.74683 negative regulation of gene expression, epigenetic 0.74873 regulation of cellular component biogenesis 0.74914 caveola 0.74932 cilium part 0.75193 blood circulation 0.75252 regulation of secretion 0.75264 negative regulation of protein import into nucleus 0.75341 neuron projection 0.7543 nonprotein amino acid metabolic process 0.75619 intracellular ligand-gated ion channel activity 0.75661 negative regulation of cellular catabolic process 0.75732 cell aging 0.75774 myosin binding 0.75797 heterophilic cell adhesion 0.75833 nucleosome organization 0.75951 sodium ion binding 0.76052 cAMP biosynthetic process 0.76135 biomineral formation 0.76159 cytosolic part 0.76206 nucleobase, nucleoside, nucleotide kinase activity 0.76236 N-acetyltransferase activity 0.76248 cellular localization 0.76313 secretory granule 0.76343 regulation of phosphoinositide 3-kinase cascade 0.7642 cell activation 0.76432 postsynaptic membrane 0.76443 translational elongation 0.76467 protein phosphatase binding 0.76704 protein targeting 0.76746 negative regulation of caspase activity 0.76817 purine ribonucleoside triphosphate metabolic process 0.77012 kinase regulator activity 0.77066 chloride channel activity 0.77172 anaphase-promoting complex 0.77232 ribosomal subunit 0.7725 nuclear hormone receptor binding 0.77558 lymphocyte mediated immunity 0.77582 regulation of insulin receptor signaling pathway 0.77605 Golgi organization 0.77664 peptide transport 0.77682 vesicle coat 0.77842 regulation of DNA repair 0.77896 pigmentation 0.78074 single-stranded RNA binding 0.78109 reverse cholesterol transport 0.78162 negative regulation of multicellular organismal process 0.78269 calmodulin binding 0.78269 positive regulation of hormone secretion 0.78293 single-stranded DNA binding 0.78394 regulation of actin filament polymerization 0.78417 negative regulation of endothelial cell proliferation 0.78512 T cell differentiation 0.7853 regulation of cellular carbohydrate catabolic process 0.78548 regulation of carbohydrate catabolic process 0.78548 clathrin coated vesicle membrane 0.78554 coated vesicle membrane 0.78554 cadherin binding 0.78577 RNA elongation from RNA polymerase II promoter 0.78601 regulation of action potential 0.78607 peptidase activator activity 0.78648 anion channel activity 0.78666 tissue regeneration 0.78714 induction of apoptosis via death domain receptors 0.78726 Golgi stack 0.78773 ubiquitin ligase complex 0.78986 positive regulation of cytokine secretion 0.78992 acyl-CoA metabolic process 0.79016 lipoprotein receptor binding 0.79087 central nervous system neuron development 0.79093 cellular monovalent inorganic cation homeostasis 0.79093 G2/M transition DNA damage checkpoint 0.79212 sex differentiation 0.79247 galactosyltransferase activity 0.79259 positive regulation of leukocyte mediated cytotoxicity 0.79259 detection of stimulus 0.79384 acid-thiol ligase activity 0.79395 ribonucleoside triphosphate metabolic process 0.79425 regulation of actin filament depolymerization 0.79425 negative regulation of actin filament polymerization 0.79437 SNARE binding 0.7965 cyclic nucleotide biosynthetic process 0.79656 negative regulation of response to external stimulus 0.79686 negative regulation of DNA metabolic process 0.79733 phospholipid catabolic process 0.79757 DNA polymerase activity 0.79828 neutrophil chemotaxis 0.79828 ER-nuclear signaling pathway 0.79935 excitatory extracellular ligand-gated ion channel activity 0.80012 positive regulation of macrophage derived foam cell differentiation 0.80041 endocytic vesicle membrane 0.80071 microtubule organizing center 0.80362 MAP kinase phosphatase activity 0.80397 MAP kinase tyrosine/serine/threonine phosphatase activity 0.80397 methionine metabolic process 0.80563 skeletal system morphogenesis 0.80575 cullin-RING ubiquitin ligase complex 0.80599 morphogenesis of embryonic epithelium 0.80646 DNA-dependent DNA replication 0.80699 negative regulation of cell activation 0.80717 multicellular organism growth 0.80723 synaptosome 0.80747 hydrogen peroxide catabolic process 0.80824 response to wounding 0.80836 nucleoside kinase activity 0.80848 fucose metabolic process 0.80919 protein phosphatase type 2A complex 0.80954 regulation of establishment of protein localization 0.8096 posttranscriptional regulation of gene expression 0.8096 inositol or phosphatidylinositol phosphatase activity 0.81079 negative regulation of transferase activity 0.81079 regulation of ATPase activity 0.81103 threonine-type peptidase activity 0.81257 threonine-type endopeptidase activity 0.81257 alpha-beta T cell activation 0.8147 microbody membrane 0.81595 peroxisomal membrane 0.81595 secretion 0.81666 androgen receptor signaling pathway 0.81909 regeneration 0.8198 negative regulation of secretion 0.82051 histone methyltransferase activity 0.82069 MAP kinase kinase kinase activity 0.82116 inactivation of MAPK activity 0.8214 regulation of organelle organization 0.82152 tRNA processing 0.82294 protein kinase activator activity 0.82336 response to wounding 0.82389 lymphocyte activation 0.82608 soluble fraction 0.82656 regulation of dephosphorylation 0.82667 cellular polysaccharide biosynthetic process 0.82709 lysosomal transport 0.82715 positive regulation of positive chemotaxis 0.82745 regulation of positive chemotaxis 0.82745 protein import into nucleus 0.82756 cysteine-type peptidase activity 0.82851 pyrimidine nucleoside triphosphate metabolic process 0.82893 methylation 0.82964 synapse assembly 0.82982 negative regulation of intracellular transport 0.83059 regulation of epidermal growth factor receptor activity 0.83094 sterol binding 0.831 negative regulation of inflammatory response 0.83118 di-, tri-valent inorganic cation transmembrane transporter activity 0.83159 regulation of phosphatase activity 0.83237 nerve-nerve synaptic transmission 0.8326 unfolded protein binding 0.83361 lysine N-acetyltransferase activity 0.83367 histone acetyltransferase activity 0.83367 microtubule organizing center organization 0.8342 cardiac cell differentiation 0.83426 negative regulation of hormone secretion 0.83474 proton transport 0.83485 cis-Golgi network 0.83497 protein tyrosine/serine/threonine phosphatase activity 0.83574 negative regulation of coagulation 0.83574 protein serine/threonine phosphatase complex 0.83634 MHC class I protein complex 0.83717 leukocyte activation 0.83723 glial cell development 0.83746 negative regulation of mitotic cell cycle 0.83829 response to nutrient levels 0.83936 mannosidase activity 0.84049 condensed chromosome 0.84049 aromatic compound biosynthetic process 0.84173 monosaccharide transmembrane transporter activity 0.84179 hexose transmembrane transporter activity 0.84179 midbody 0.84197 heart looping 0.84215 regulation of amine transport 0.84262 leukocyte activation during immune response 0.84339 cell activation during immune response 0.84339 macromolecular complex disassembly 0.8441 cellular macromolecular complex disassembly 0.8441 regulation of steroid biosynthetic process 0.84487 single-stranded RNA binding 0.84511 protein-DNA complex 0.84612 regulation of cytokine biosynthetic process 0.84707 acetylcholine receptor activity 0.84713 ubiquitin-specific protease activity 0.84784 inorganic anion transmembrane transporter activity 0.84784 transcription, DNA-dependent 0.84861 pyrimidine ribonucleotide biosynthetic process 0.84867 DNA integrity checkpoint 0.84932 anchored to plasma membrane 0.8495 Wnt receptor signaling pathway, calcium modulating pathway 0.85039 aminoglycan metabolic process 0.8505 double-stranded DNA binding 0.85122 inflammatory response 0.85139 chromatin 0.85187 triglyceride lipase activity 0.85222 regulation of response to stress 0.85234 pyruvate metabolic process 0.8524 N-acetylglucosamine metabolic process 0.8524 negative regulation of actin filament depolymerization 0.8524 actin filament capping 0.8524 vacuolar transport 0.85276 mitochondrial transport 0.85282 tissue development 0.85394 cellular macromolecule localization 0.854 acylglycerol O-acyltransferase activity 0.85459 regulation of glycolysis 0.85471 tRNA methyltransferase activity 0.85554 regulation of monooxygenase activity 0.85566 epidermal growth factor receptor signaling pathway 0.85708 negative regulation of endocytosis 0.8572 ion gated channel activity 0.85732 nonmotile primary cilium 0.85738 negative regulation of defense response 0.85845 protein ubiquitination during ubiquitin-dependent protein catabolic process 0.85898 monooxygenase activity 0.85928 cell chemotaxis 0.85928 fatty-acid ligase activity 0.85945 placenta development 0.86011 deaminase activity 0.86034 integral to mitochondrial membrane 0.86064 regulation of lipid transport 0.86189 acetylcholine binding 0.86313 covalent chromatin modification 0.86349 positive regulation of monooxygenase activity 0.86372 regulation of synaptic plasticity 0.86384 histone deacetylase binding 0.86396 ventricular cardiac muscle tissue morphogenesis 0.86473 neuron recognition 0.86598 glutathione metabolic process 0.8668 synaptic vesicle transport 0.86752 chromosome condensation 0.86763 nuclear ubiquitin ligase complex 0.86805 intra-Golgi vesicle-mediated transport 0.86811 centriole 0.86829 transferase activity, transferring acyl groups 0.869 spleen development 0.86977 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 0.86995 cellular response to DNA damage stimulus 0.8703 endosome 0.87048 RNA biosynthetic process 0.87172 response to lipopolysaccharide 0.87172 regulation of steroid metabolic process 0.87267 regulation of RNA splicing 0.87315 calcium-activated potassium channel activity 0.87404 meiosis 0.87421 small conjugating protein-specific protease activity 0.87439 microtubule organizing center part 0.87451 histone deacetylase complex 0.87469 RNA polymerase activity 0.87487 DNA-directed RNA polymerase activity 0.87487 embryo implantation 0.87493 cellular protein localization 0.87718 cellular protein localization 0.87759 nucleotide-excision repair, DNA damage removal 0.87765 ATP metabolic process 0.87771 di-, tri-valent inorganic cation transport 0.87819 cellular macromolecular complex subunit organization 0.87908 negative regulation of actin filament depolymerization 0.87919 anchored to membrane 0.87985 ion transmembrane transport 0.88109 glycerophospholipid metabolic process 0.8818 negative regulation of transport 0.8818 centrosome organization 0.88204 cyclic nucleotide binding 0.88228 cell recognition 0.88251 positive regulation of lipid biosynthetic process 0.88287 one-carbon metabolic process 0.88293 one-carbon metabolic process 0.88293 acrosomal vesicle 0.88305 L-fucose metabolic process 0.88352 RNA modification 0.88405 endosome to lysosome transport 0.88471 inositol metabolic process 0.88512 superoxide metabolic process 0.88607 histone modification 0.88631 negative regulation of neurological system process 0.88637 phosphorus-oxygen lyase activity 0.88684 sugar transmembrane transporter activity 0.88743 regulation of neuronal synaptic plasticity 0.88779 regulation of lipoprotein lipase activity 0.88886 cellular component maintenance 0.88951 fucosyltransferase activity 0.88969 regulation of peptidyl-tyrosine phosphorylation 0.88992 protein amino acid lipidation 0.89111 UDP-galactosyltransferase activity 0.89229 tube lumen formation 0.89265 positive regulation of ion transport 0.89336 negative regulation of T cell activation 0.89342 NuRD complex 0.89407 contractile fiber part 0.89407 DNA catabolic process, endonucleolytic 0.89538 positive regulation of oxidoreductase activity 0.89585 cell structure disassembly during apoptosis 0.89609 signal sequence binding 0.89686 extracellular ligand-gated ion channel activity 0.89745 hydrogen peroxide metabolic process 0.89787 calcium channel regulator activity 0.89798 NAD metabolic process 0.8984 determination of symmetry 0.89852 determination of bilateral symmetry 0.89852 determination of left/right symmetry 0.89852 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 0.89911 double-stranded RNA binding 0.89929 Z disc 0.8997 intrinsic to peroxisomal membrane 0.90041 nuclear heterochromatin 0.90041 integral to peroxisomal membrane 0.90041 site of polarized growth 0.90124 growth cone 0.90124 site of polarized growth 0.90124 site of polarized growth 0.90124 positive regulation of peptidyl-tyrosine phosphorylation 0.90178 hydrogen ion transporting ATP synthase activity, rotational mechanism 0.90237 embryonic morphogenesis 0.90243 methyltransferase activity 0.90296 RNA modification 0.90332 heme binding 0.90362 prenyltransferase activity 0.90397 response to cytokine stimulus 0.90439 regulation of cell projection assembly 0.90445 DNA-dependent ATPase activity 0.90545 ligase activity, forming carbon-sulfur bonds 0.90569 acid phosphatase activity 0.90569 microtubule 0.9067 superoxide anion generation 0.90842 T cell activation 0.90901 sterol transport 0.90907 cholesterol transport 0.90907 phosphotransferase activity, phosphate group as acceptor 0.90931 regulation of NF-kappaB import into nucleus 0.90954 cAMP metabolic process 0.90966 erythrocyte differentiation 0.90978 regulation of muscle cell differentiation 0.9099 immune response-activating signal transduction 0.91043 immune response-regulating signal transduction 0.91043 cell-cell adhesion 0.91055 fatty acid binding 0.91079 lipoprotein metabolic process 0.91085 regulation of MAPKKK cascade 0.91091 zinc ion transport 0.91191 somitogenesis 0.91263 virus-host interaction 0.91322 microbody part 0.91334 peroxisomal part 0.91334 microtubule-based process 0.9134 nicotinic acetylcholine-activated cation-selective channel activity 0.91357 UDP-glycosyltransferase activity 0.91423 triglyceride-rich lipoprotein particle 0.91429 very-low-density lipoprotein particle 0.91429 DNA recombination 0.91571 negative regulation of nucleocytoplasmic transport 0.91648 protein methyltransferase activity 0.91719 methyltransferase activity 0.91743 striated muscle cell differentiation 0.91938 pteridine and derivative biosynthetic process 0.9198 peptidyl-lysine modification 0.92098 calcium activated cation channel activity 0.92116 adenylyltransferase activity 0.92128 embryonic skeletal system development 0.92175 cellular carbohydrate biosynthetic process 0.92258 cholesterol biosynthetic process 0.92347 female pregnancy 0.92401 negative regulation of insulin receptor signaling pathway 0.92413 actin cytoskeleton 0.9243 oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor 0.92519 microtubule associated complex 0.92537 CTP metabolic process 0.9259 pyrimidine nucleoside triphosphate biosynthetic process 0.9259 pyrimidine ribonucleoside triphosphate metabolic process 0.9259 pyrimidine ribonucleoside triphosphate biosynthetic process 0.9259 CTP biosynthetic process 0.9259 regulation of smooth muscle cell proliferation 0.92679 regulation of protein ubiquitination 0.92762 B cell mediated immunity 0.92786 pyrimidine ribonucleotide metabolic process 0.92845 ATPase activity, coupled to transmembrane movement of substances 0.92869 response to vitamin 0.9291 regulation of chemokine production 0.92916 regulation of leukocyte mediated cytotoxicity 0.92934 embryonic morphogenesis 0.92964 mitotic spindle organization 0.92988 leukocyte chemotaxis 0.92999 gastrulation 0.93005 germ cell development 0.93231 negative regulation of peptidase activity 0.93254 positive regulation of endothelial cell proliferation 0.93278 aspartic-type peptidase activity 0.93402 aspartic-type endopeptidase activity 0.93402 DNA fragmentation involved in apoptosis 0.93402 interaction with host 0.93474 axoneme part 0.93497 forelimb morphogenesis 0.93557 ER-Golgi intermediate compartment 0.93705 oligosaccharide metabolic process 0.93823 leukocyte differentiation 0.93912 hormone receptor binding 0.93995 cardiac muscle tissue morphogenesis 0.94055 muscle tissue morphogenesis 0.94055 regulation of multi-organism process 0.94078 nucleus organization 0.94096 axoneme 0.94167 regulation of cytokine production during immune response 0.94173 cellular macromolecular complex assembly 0.94173 ribonucleoprotein binding 0.94179 damaged DNA binding 0.94232 regulation of protein localization 0.94268 growth factor activity 0.94303 late endosome 0.94315 regulation of cellular component size 0.94381 response to calcium ion 0.94392 Golgi vesicle transport 0.9441 mRNA binding 0.94458 regulation of viral reproduction 0.94469 tubulin binding 0.94475 locomotory behavior 0.94481 steroid binding 0.94511 'de novo' protein folding 0.94535 DNA integration 0.94535 glycosaminoglycan metabolic process 0.94541 cytoplasmic sequestering of protein 0.94547 B cell activation 0.94606 hydrogen transport 0.94624 regulation of membrane protein ectodomain proteolysis 0.94641 small ribosomal subunit 0.94665 anterior/posterior pattern formation 0.94677 transferase activity, transferring acyl groups other than amino-acyl groups 0.94825 hindlimb morphogenesis 0.94825 tetrapyrrole binding 0.94873 synapse organization 0.94902 phosphotransferase activity, for other substituted phosphate groups 0.94914 vacuolar part 0.9492 glucosamine metabolic process 0.94967 vesicle coating 0.94997 metallopeptidase activity 0.95044 actin filament-based movement 0.95187 N-terminal protein amino acid modification 0.95216 cyclase activity 0.95228 heterochromatin 0.95246 negative regulation of kinase activity 0.95252 protein import 0.9527 chromosome 0.95287 DNA catabolic process 0.95293 microtubule binding 0.95335 RNA elongation 0.95347 cellular component disassembly 0.95661 tricarboxylic acid cycle 0.95839 acetyl-CoA catabolic process 0.95839 regulation of inflammatory response 0.95857 protease binding 0.95898 vesicle targeting 0.95975 cytokinesis 0.95981 hydrolase activity, hydrolyzing N-glycosyl compounds 0.95993 glycoprotein biosynthetic process 0.96117 actin filament binding 0.96129 lipid modification 0.96159 carbohydrate transmembrane transporter activity 0.96183 ribosome binding 0.96266 mitotic chromosome condensation 0.96331 homophilic cell adhesion 0.96331 transcription 0.96354 regulation of tumor necrosis factor production 0.96426 transcription factor TFTC complex 0.96568 photoreceptor cell maintenance 0.9658 carbohydrate binding 0.96799 kinesin complex 0.96811 chaperone binding 0.96882 developmental induction 0.97036 cell-cell signaling involved in cell fate specification 0.97036 regulation of homeostatic process 0.97048 S-adenosylmethionine-dependent methyltransferase activity 0.97149 thiolester hydrolase activity 0.97214 negative regulation of myeloid cell differentiation 0.97309 acyltransferase activity 0.97333 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 0.97457 adaptive immune response 0.97457 positive regulation of cytokine biosynthetic process 0.97552 secretory granule membrane 0.97765 mitochondrial membrane organization 0.97854 cholesterol transporter activity 0.97973 cellular aldehyde metabolic process 0.98008 carbon-sulfur lyase activity 0.98074 nucleotidyltransferase activity 0.98216 nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity 0.98234 transferase activity, transferring one-carbon groups 0.98257 peptide hormone processing 0.98524 tRNA modification 0.98554 metallocarboxypeptidase activity 0.98654 translation 0.98654 cell cycle arrest 0.98684 mitochondrial ribosome 0.98708 organellar ribosome 0.98708 GTPase activity 0.98826 ATPase activity, coupled to movement of substances 0.99259 anion transmembrane transporter activity 0.99259 regulation of interleukin-1 production 0.99283 presynaptic membrane 0.99312 mitochondrial intermembrane space 0.99443 phosphoprotein phosphatase inhibitor activity 0.9952 generation of a signal involved in cell-cell signaling 0.99929 cilium axoneme 0.99935 neural tube closure 0.99953 tube closure 0.99953