GO ID number GO description ROC bias 70256 negative regulation of mucus secretion 1.000000 70255 regulation of mucus secretion 1.000000 46061 dATP catabolic process 1.000000 46060 dATP metabolic process 1.000000 46085 adenosine metabolic process 1.000000 46090 deoxyadenosine metabolic process 1.000000 46111 xanthine biosynthetic process 1.000000 46110 xanthine metabolic process 1.000000 46122 purine deoxyribonucleoside metabolic process 1.000000 46124 purine deoxyribonucleoside catabolic process 1.000000 46103 inosine biosynthetic process 1.000000 2314 germinal center B cell differentiation 1.000000 9204 deoxyribonucleoside triphosphate catabolic process 1.000000 9215 purine deoxyribonucleoside triphosphate metabolic process 1.000000 9217 purine deoxyribonucleoside triphosphate catabolic process 1.000000 6154 adenosine catabolic process 1.000000 6157 deoxyadenosine catabolic process 1.000000 60167 regulation of adenosine receptor signaling pathway 1.000000 60169 negative regulation of adenosine receptor signaling pathway 1.000000 60405 regulation of penile erection 1.000000 60407 negative regulation of penile erection 1.000000 43173 nucleotide salvage 1.000000 32261 purine nucleotide salvage 1.000000 46014 negative regulation of T cell homeostatic proliferation 0.999952 2327 immature B cell differentiation 0.999952 2329 pre-B cell differentiation 0.999952 33606 chemokine receptor transport within lipid bilayer 0.999952 33634 positive regulation of cell-cell adhesion mediated by integrin 0.999952 34111 negative regulation of homotypic cell-cell adhesion 0.999952 34110 regulation of homotypic cell-cell adhesion 0.999952 34119 negative regulation of erythrocyte aggregation 0.999952 34118 regulation of erythrocyte aggregation 0.999952 34107 negative regulation of erythrocyte clearance 0.999952 34106 regulation of erythrocyte clearance 0.999952 32910 regulation of transforming growth factor-beta3 production 0.999952 32913 negative regulation of transforming growth factor-beta3 production 0.999952 32600 chemokine receptor transport out of membrane raft 0.999952 32594 protein transport within lipid bilayer 0.999952 32596 protein transport into membrane raft 0.999952 32595 B cell receptor transport within lipid bilayer 0.999952 32597 B cell receptor transport into membrane raft 0.999952 32599 protein transport out of membrane raft 0.999952 42103 positive regulation of T cell homeostatic proliferation 0.999952 2520 immune system development 0.999903 48643 positive regulation of skeletal muscle tissue development 0.999903 33688 regulation of osteoblast proliferation 0.999903 33689 negative regulation of osteoblast proliferation 0.999903 48743 positive regulation of skeletal muscle fiber development 0.999903 43375 CD8-positive, alpha-beta T cell lineage commitment 0.999903 43369 CD4-positive or CD8-positive, alpha-beta T cell lineage commitment 0.999903 21747 cochlear nucleus development 0.999903 32847 regulation of cellular pH reduction 0.999903 32848 negative regulation of cellular pH reduction 0.999903 14041 regulation of neuron maturation 0.999903 14042 positive regulation of neuron maturation 0.999903 2513 tolerance induction to self antigen 0.999855 42831 defense response to fungus 0.999855 9817 defense response to fungus, incompatible interaction 0.999855 9814 defense response, incompatible interaction 0.999855 51280 negative regulation of release of sequestered calcium ion into cytosol 0.999855 10763 positive regulation of fibroblast migration 0.999855 10762 regulation of fibroblast migration 0.999855 32740 positive regulation of interleukin-17 production 0.999831 32660 regulation of interleukin-17 production 0.999831 70051 fibrinogen binding 0.999807 2604 regulation of dendritic cell antigen processing and presentation 0.999807 2605 negative regulation of dendritic cell antigen processing and presentation 0.999807 2578 negative regulation of antigen processing and presentation 0.999807 2577 regulation of antigen processing and presentation 0.999807 2580 regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 0.999807 2581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 0.999807 48603 fibroblast growth factor 2 binding 0.999807 10749 regulation of nitric oxide mediated signal transduction 0.999807 10752 regulation of cGMP-mediated signaling 0.999807 10751 negative regulation of nitric oxide mediated signal transduction 0.999807 10754 negative regulation of cGMP-mediated signaling 0.999807 10759 positive regulation of macrophage chemotaxis 0.999807 10758 regulation of macrophage chemotaxis 0.999807 10757 negative regulation of plasminogen activation 0.999807 43652 engulfment of apoptotic cell 0.999807 2381 immunoglobulin production during immune response 0.999759 34135 regulation of toll-like receptor 2 signaling pathway 0.999759 34136 negative regulation of toll-like receptor 2 signaling pathway 0.999759 32500 muramyl dipeptide binding 0.999759 32701 negative regulation of interleukin-18 production 0.999759 32499 detection of peptidoglycan 0.999759 32498 detection of muramyl dipeptide 0.999759 2439 chronic inflammatory response to antigenic stimulus 0.999710 2437 inflammatory response to antigenic stimulus 0.999710 45994 positive regulation of translational initiation by iron 0.999710 46136 positive regulation of vitamin metabolic process 0.999686 60557 positive regulation of vitamin D biosynthetic process 0.999686 31703 type 2 angiotensin receptor binding 0.999662 48143 astrocyte activation 0.999662 1998 angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure 0.999662 1999 renal response to blood flow during renin-angiotensin regulation of systemic arterial blood pressure 0.999662 14873 response to muscle activity involved in regulation of muscle adaptation 0.999662 33139 regulation of peptidyl-serine phosphorylation of STAT protein 0.999614 33141 positive regulation of peptidyl-serine phosphorylation of STAT protein 0.999614 60549 regulation of fructose 1,6-bisphosphate 1-phosphatase activity 0.999614 60552 positive regulation of fructose 1,6-bisphosphate metabolic process 0.999614 60551 regulation of fructose 1,6-bisphosphate metabolic process 0.999614 60550 positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity 0.999614 32113 regulation of carbohydrate phosphatase activity 0.999614 5133 interferon-gamma receptor binding 0.999614 43268 positive regulation of potassium ion transport 0.999565 60291 long-term synaptic potentiation 0.999565 60292 long term synaptic depression 0.999565 1590 dopamine D1 receptor activity 0.999565 35106 operant conditioning 0.999565 46960 sensitization 0.999565 46958 nonassociative learning 0.999565 33026 negative regulation of mast cell apoptosis 0.999517 2431 Fc receptor mediated stimulatory signaling pathway 0.999517 1803 regulation of type III hypersensitivity 0.999517 1805 positive regulation of type III hypersensitivity 0.999517 42590 antigen processing and presentation of exogenous peptide antigen via MHC class I 0.999517 70365 hepatocyte differentiation 0.999469 55005 ventricular cardiac myofibril development 0.999469 50692 DBD domain binding 0.999469 50693 LBD domain binding 0.999469 60214 endocardium formation 0.999469 60421 positive regulation of heart growth 0.999469 60414 aorta smooth muscle tissue morphogenesis 0.999469 43049 otic placode formation 0.999469 60836 lymphatic endothelial cell differentiation 0.999469 60298 positive regulation of sarcomere organization 0.999445 48546 digestive tract morphogenesis 0.999421 48859 formation of anatomical boundary 0.999421 48708 astrocyte differentiation 0.999421 60020 Bergmann glial cell differentiation 0.999421 60738 epithelial-mesenchymal signaling involved in prostate gland development 0.999421 60684 epithelial-mesenchymal cell signaling 0.999421 7228 positive regulation of hh target transcription factor activity 0.999421 31707 endothelin A receptor binding 0.999372 42313 protein kinase C deactivation 0.999372 51771 negative regulation of nitric-oxide synthase biosynthetic process 0.999372 51769 regulation of nitric-oxide synthase biosynthetic process 0.999372 33623 regulation of integrin activation 0.999372 33625 positive regulation of integrin activation 0.999372 16532 superoxide dismutase copper chaperone activity 0.999324 48553 negative regulation of metalloenzyme activity 0.999324 2082 regulation of oxidative phosphorylation 0.999324 60003 copper ion export 0.999324 51542 elastin biosynthetic process 0.999324 10273 detoxification of copper ion 0.999324 2686 negative regulation of leukocyte migration 0.999324 60559 positive regulation of calcidiol 1-monooxygenase activity 0.999324 50765 negative regulation of phagocytosis 0.999300 10692 regulation of alkaline phosphatase activity 0.999276 10693 negative regulation of alkaline phosphatase activity 0.999276 48818 positive regulation of hair follicle maturation 0.999276 48819 regulation of hair follicle maturation 0.999276 51794 regulation of catagen 0.999276 51795 positive regulation of catagen 0.999276 70627 ferrous iron import 0.999227 70826 paraferritin complex 0.999227 70835 chromium ion transmembrane transporter activity 0.999227 60586 multicellular organismal iron ion homeostasis 0.999227 15692 lead ion transport 0.999227 15676 vanadium ion transport 0.999227 15675 nickel ion transport 0.999227 5384 manganese ion transmembrane transporter activity 0.999227 15100 vanadium ion transmembrane transporter activity 0.999227 15094 lead ion transmembrane transporter activity 0.999227 15099 nickel ion transmembrane transporter activity 0.999227 15086 cadmium ion transmembrane transporter activity 0.999227 31768 ghrelin receptor binding 0.999179 46010 positive regulation of circadian sleep/wake cycle, non-REM sleep 0.999179 51459 regulation of adrenocorticotropin secretion 0.999179 51461 positive regulation of adrenocorticotropin secretion 0.999179 60160 negative regulation of dopamine receptor signaling pathway 0.999131 1670 dopamine D2 receptor activity 0.999131 34116 positive regulation of heterotypic cell-cell adhesion 0.999131 2924 negative regulation of humoral immune response mediated by circulating immunoglobulin 0.999083 2895 regulation of central B cell tolerance induction 0.999083 2897 positive regulation of central B cell tolerance induction 0.999083 2890 negative regulation of immunoglobulin mediated immune response 0.999083 2713 negative regulation of B cell mediated immunity 0.999083 2648 positive regulation of central tolerance induction 0.999083 2646 regulation of central tolerance induction 0.999083 2635 negative regulation of germinal center formation 0.999083 2508 central tolerance induction 0.999083 60412 ventricular septum morphogenesis 0.999066 3280 cardiac septum morphogenesis 0.999066 31954 positive regulation of protein amino acid autophosphorylation 0.999034 60266 negative regulation of respiratory burst during acute inflammatory response 0.999034 60268 negative regulation of respiratory burst 0.999034 70587 regulation of cell-cell adhesion involved in gastrulation 0.999018 10470 regulation of gastrulation 0.999018 34114 regulation of heterotypic cell-cell adhesion 0.999018 32805 positive regulation of low-density lipoprotein receptor catabolic process 0.998986 46911 metal chelating activity 0.998986 10665 regulation of cardiac muscle cell apoptosis 0.998938 10667 negative regulation of cardiac muscle cell apoptosis 0.998938 10662 regulation of striated muscle cell apoptosis 0.998938 10664 negative regulation of striated muscle cell apoptosis 0.998938 60413 atrial septum morphogenesis 0.998938 51929 positive regulation of calcium ion transport via voltage-gated calcium channel activity 0.998938 46127 pyrimidine deoxyribonucleoside catabolic process 0.998889 46104 thymidine metabolic process 0.998889 6145 purine base catabolic process 0.998889 4159 dihydrouracil dehydrogenase (NAD+) activity 0.998889 6214 thymidine catabolic process 0.998889 17113 dihydropyrimidine dehydrogenase (NADP+) activity 0.998889 60059 embryonic retina morphogenesis in camera-type eye 0.998889 31914 negative regulation of synaptic plasticity 0.998841 22038 corpus callosum development 0.998841 21695 cerebellar cortex development 0.998841 21697 cerebellar cortex formation 0.998841 30549 acetylcholine receptor activator activity 0.998841 14044 Schwann cell development 0.998841 2661 regulation of B cell tolerance induction 0.998841 2663 positive regulation of B cell tolerance induction 0.998841 2840 regulation of T cell mediated immune response to tumor cell 0.998817 2842 positive regulation of T cell mediated immune response to tumor cell 0.998817 2455 humoral immune response mediated by circulating immunoglobulin 0.998793 2315 marginal zone B cell differentiation 0.998793 45064 T-helper 2 cell differentiation 0.998793 32996 Bcl3-Bcl10 complex 0.998793 70560 protein secretion by platelet 0.998745 10925 positive regulation of inositol-polyphosphate 5-phosphatase activity 0.998745 10924 regulation of inositol-polyphosphate 5-phosphatase activity 0.998745 10920 negative regulation of inositol phosphate biosynthetic process 0.998745 10919 regulation of inositol phosphate biosynthetic process 0.998745 60305 regulation of cell diameter 0.998745 30845 inhibition of phospholipase C activity involved in G-protein coupled receptor signaling pathway 0.998745 2367 cytokine production during immune response 0.998720 10739 positive regulation of protein kinase A signaling cascade 0.998696 10738 regulation of protein kinase A signaling cascade 0.998696 10804 negative regulation of tumor necrosis factor-mediated signaling pathway 0.998696 10803 regulation of tumor necrosis factor-mediated signaling pathway 0.998696 34115 negative regulation of heterotypic cell-cell adhesion 0.998696 31584 activation of phospholipase D activity 0.998696 31583 activation of phospholipase D activity by G-protein coupled receptor protein signaling pathway 0.998696 51582 positive regulation of neurotransmitter uptake 0.998696 51586 positive regulation of dopamine uptake 0.998696 51944 positive regulation of catecholamine uptake during transmission of nerve impulse 0.998696 10944 negative regulation of transcription by competitive promoter binding 0.998648 10719 negative regulation of epithelial to mesenchymal transition 0.998648 10801 negative regulation of peptidyl-threonine phosphorylation 0.998648 60373 regulation of ventricular cardiomyocyte membrane depolarization 0.998648 34333 adherens junction assembly 0.998648 33004 negative regulation of mast cell activation 0.998600 2246 healing during inflammatory response 0.998600 43301 negative regulation of leukocyte degranulation 0.998600 43305 negative regulation of mast cell degranulation 0.998600 60297 regulation of sarcomere organization 0.998600 1591 dopamine receptor activity, coupled via Gi/Go 0.998600 34776 response to histamine 0.998600 31435 mitogen-activated protein kinase kinase kinase binding 0.998551 2649 regulation of tolerance induction to self antigen 0.998551 2651 positive regulation of tolerance induction to self antigen 0.998551 60264 regulation of respiratory burst during acute inflammatory response 0.998551 70164 negative regulation of adiponectin secretion 0.998503 60353 regulation of cell adhesion molecule production 0.998503 60355 positive regulation of cell adhesion molecule production 0.998503 32764 negative regulation of mast cell cytokine production 0.998503 10767 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage 0.998455 10766 negative regulation of sodium ion transport 0.998455 10768 negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage 0.998455 44007 dissemination or transmission of symbiont from host 0.998455 19871 sodium channel inhibitor activity 0.998455 51821 dissemination or transmission of organism from other organism during symbiotic interaction 0.998455 19089 transmission of virus 0.998455 2701 negative regulation of production of molecular mediator of immune response 0.998422 2719 negative regulation of cytokine production during immune response 0.998422 46056 dADP metabolic process 0.998406 9136 purine nucleoside diphosphate biosynthetic process 0.998406 9153 purine deoxyribonucleotide biosynthetic process 0.998406 9180 purine ribonucleoside diphosphate biosynthetic process 0.998406 9182 purine deoxyribonucleoside diphosphate metabolic process 0.998406 9183 purine deoxyribonucleoside diphosphate biosynthetic process 0.998406 9188 ribonucleoside diphosphate biosynthetic process 0.998406 6173 dADP biosynthetic process 0.998406 6172 ADP biosynthetic process 0.998406 33028 myeloid cell apoptosis 0.998382 1781 neutrophil apoptosis 0.998382 48294 negative regulation of isotype switching to IgE isotypes 0.998358 43380 regulation of memory T cell differentiation 0.998358 45829 negative regulation of isotype switching 0.998358 2923 regulation of humoral immune response mediated by circulating immunoglobulin 0.998358 45188 regulation of circadian sleep/wake cycle, non-REM sleep 0.998334 50883 musculoskeletal movement, spinal reflex action 0.998310 1592 dopamine D3 receptor activity 0.998310 46102 inosine metabolic process 0.998310 10765 positive regulation of sodium ion transport 0.998286 48807 female genitalia morphogenesis 0.998262 60065 uterus development 0.998262 60068 vagina development 0.998262 34632 retinol transporter activity 0.998262 34633 retinol transport 0.998262 46865 terpenoid transport 0.998262 46864 isoprenoid transport 0.998262 1593 dopamine D4 receptor activity 0.998213 2725 negative regulation of T cell cytokine production 0.998165 31064 negative regulation of histone deacetylation 0.998165 31063 regulation of histone deacetylation 0.998165 32693 negative regulation of interleukin-10 production 0.998165 51525 NFAT protein binding 0.998165 51400 BH domain binding 0.998141 51434 BH3 domain binding 0.998141 48631 regulation of skeletal muscle tissue growth 0.998117 48633 positive regulation of skeletal muscle tissue growth 0.998117 4941 beta2-adrenergic receptor activity 0.998117 8179 adenylate cyclase binding 0.998117 46098 guanine metabolic process 0.998068 46099 guanine biosynthetic process 0.998068 33240 positive regulation of cellular amine metabolic process 0.998068 6178 guanine salvage 0.998068 45915 positive regulation of catecholamine metabolic process 0.998068 45964 positive regulation of dopamine metabolic process 0.998068 60267 positive regulation of respiratory burst 0.998068 34143 regulation of toll-like receptor 4 signaling pathway 0.998020 34145 positive regulation of toll-like receptor 4 signaling pathway 0.998020 34123 positive regulation of toll-like receptor signaling pathway 0.998020 60265 positive regulation of respiratory burst during acute inflammatory response 0.998020 51636 Gram-negative bacterial cell surface binding 0.998020 45914 negative regulation of catecholamine metabolic process 0.997972 45963 negative regulation of dopamine metabolic process 0.997972 51957 positive regulation of amino acid transport 0.997972 14057 positive regulation of acetylcholine secretion 0.997972 14052 regulation of gamma-aminobutyric acid secretion 0.997972 14054 positive regulation of gamma-aminobutyric acid secretion 0.997972 2922 positive regulation of humoral immune response 0.997948 2925 positive regulation of humoral immune response mediated by circulating immunoglobulin 0.997948 60389 pathway-restricted SMAD protein phosphorylation 0.997940 70106 interleukin-27-mediated signaling pathway 0.997924 70110 ciliary neurotrophic factor receptor complex 0.997924 4921 interleukin-11 receptor activity 0.997924 19970 interleukin-11 binding 0.997924 16489 immunoglobulin receptor activity 0.997924 1812 positive regulation of type I hypersensitivity 0.997924 1810 regulation of type I hypersensitivity 0.997924 19767 IgE receptor activity 0.997924 42510 regulation of tyrosine phosphorylation of Stat1 protein 0.997923 42511 positive regulation of tyrosine phosphorylation of Stat1 protein 0.997923 70814 hydrogen sulfide biosynthetic process 0.997875 70813 hydrogen sulfide metabolic process 0.997875 9093 cysteine catabolic process 0.997875 43418 homocysteine catabolic process 0.997875 4122 cystathionine beta-synthase activity 0.997875 6535 cysteine biosynthetic process from serine 0.997875 98 sulfur amino acid catabolic process 0.997875 44273 sulfur compound catabolic process 0.997875 19448 L-cysteine catabolic process 0.997875 19343 cysteine biosynthetic process via cystathionine 0.997875 1711 endodermal cell fate commitment 0.997827 45362 positive regulation of interleukin-1 biosynthetic process 0.997779 45360 regulation of interleukin-1 biosynthetic process 0.997779 50725 positive regulation of interleukin-1 beta biosynthetic process 0.997779 50722 regulation of interleukin-1 beta biosynthetic process 0.997779 50752 regulation of fractalkine biosynthetic process 0.997779 50754 positive regulation of fractalkine biosynthetic process 0.997779 32644 regulation of fractalkine production 0.997779 1774 microglial cell activation 0.997779 45724 positive regulation of flagellum assembly 0.997730 50893 sensory processing 0.997730 30092 regulation of flagellum assembly 0.997730 34454 microtubule anchoring at centrosome 0.997730 60694 regulation of cholesterol transporter activity 0.997682 60695 negative regulation of cholesterol transporter activity 0.997682 48291 isotype switching to IgG isotypes 0.997634 2368 B cell cytokine production 0.997634 32727 positive regulation of interferon-alpha production 0.997634 32481 positive regulation of type I interferon production 0.997634 33630 positive regulation of cell adhesion mediated by integrin 0.997601 31999 negative regulation of fatty acid beta-oxidation 0.997586 46322 negative regulation of fatty acid oxidation 0.997586 14850 response to muscle activity 0.997585 45750 positive regulation of S phase of mitotic cell cycle 0.997561 10661 positive regulation of muscle cell apoptosis 0.997553 34393 positive regulation of smooth muscle cell apoptosis 0.997553 70509 calcium ion import 0.997537 31448 positive regulation of fast-twitch skeletal muscle fiber contraction 0.997537 31446 regulation of fast-twitch skeletal muscle fiber contraction 0.997537 45989 positive regulation of striated muscle contraction 0.997537 32471 reduction of endoplasmic reticulum calcium ion concentration 0.997537 32470 elevation of endoplasmic reticulum calcium ion concentration 0.997537 14724 regulation of twitch skeletal muscle contraction 0.997537 51561 elevation of mitochondrial calcium ion concentration 0.997537 51560 mitochondrial calcium ion homeostasis 0.997537 2674 negative regulation of acute inflammatory response 0.997537 60046 regulation of acrosome reaction 0.997489 60054 positive regulation of epithelial cell proliferation involved in wound healing 0.997489 60058 positive regulation of apoptosis involved in mammary gland involution 0.997489 30312 external encapsulating structure 0.997489 30112 glycocalyx 0.997489 21978 telencephalon regionalization 0.997489 51659 maintenance of mitochondrion location 0.997489 51657 maintenance of organelle location 0.997489 45721 negative regulation of gluconeogenesis 0.997489 45759 negative regulation of action potential 0.997441 21771 lateral geniculate nucleus development 0.997441 33864 positive regulation of NAD(P)H oxidase activity 0.997416 10698 acetyltransferase activator activity 0.997416 2018 renin-angiotensin regulation of aldosterone production 0.997416 44062 regulation of excretion 0.997416 51541 elastin metabolic process 0.997416 3078 regulation of natriuresis 0.997416 30730 sequestering of triglyceride 0.997408 2739 regulation of cytokine secretion during immune response 0.997404 2740 negative regulation of cytokine secretion during immune response 0.997404 60620 regulation of cholesterol import 0.997392 60621 negative regulation of cholesterol import 0.997392 34121 regulation of toll-like receptor signaling pathway 0.997392 45794 negative regulation of cell volume 0.997344 60082 eye blink reflex 0.997344 60083 smooth muscle contraction involved in micturition 0.997344 60072 large conductance calcium-activated potassium channel activity 0.997344 30007 cellular potassium ion homeostasis 0.997344 34465 response to carbon monoxide 0.997344 42536 negative regulation of tumor necrosis factor biosynthetic process 0.997312 32570 response to progesterone stimulus 0.997305 43217 myelin maintenance 0.997296 32287 myelin maintenance in the peripheral nervous system 0.997296 33025 regulation of mast cell apoptosis 0.997272 32763 regulation of mast cell cytokine production 0.997259 45355 negative regulation of interferon-alpha biosynthetic process 0.997248 30886 negative regulation of myeloid dendritic cell activation 0.997248 5141 interleukin-10 receptor binding 0.997248 14874 response to stimulus involved in regulation of muscle adaptation 0.997223 10702 regulation of histolysis 0.997199 10703 negative regulation of histolysis 0.997199 10715 regulation of extracellular matrix disassembly 0.997199 10716 negative regulation of extracellular matrix disassembly 0.997199 10711 negative regulation of collagen catabolic process 0.997199 10710 regulation of collagen catabolic process 0.997199 60311 negative regulation of elastin catabolic process 0.997199 60310 regulation of elastin catabolic process 0.997199 60313 negative regulation of blood vessel remodeling 0.997199 60312 regulation of blood vessel remodeling 0.997199 14819 regulation of skeletal muscle contraction 0.997199 16631 enoyl-[acyl-carrier-protein] reductase activity 0.997151 4313 [acyl-carrier-protein] S-acetyltransferase activity 0.997151 4317 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity 0.997151 4316 3-oxoacyl-[acyl-carrier-protein] reductase activity 0.997151 4319 enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity 0.997151 19171 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity 0.997151 60394 negative regulation of pathway-restricted SMAD protein phosphorylation 0.997151 30617 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity 0.997151 14806 smooth muscle hyperplasia 0.997151 34616 response to laminar fluid shear stress 0.997151 70091 glucagon secretion 0.997103 10987 negative regulation of high-density lipoprotein particle clearance 0.997054 10897 negative regulation of triglyceride catabolic process 0.997054 34122 negative regulation of toll-like receptor signaling pathway 0.997030 10634 positive regulation of epithelial cell migration 0.997022 10632 regulation of epithelial cell migration 0.997022 44003 modification by symbiont of host morphology or physiology 0.997022 43423 3-phosphoinositide-dependent protein kinase binding 0.997006 5009 insulin receptor activity 0.997006 19087 transformation of host cell by virus 0.997006 52043 modification by symbiont of host cellular component 0.996982 52025 modification by symbiont of host cell membrane 0.996982 52111 modification by symbiont of host structure 0.996982 52188 modification of cellular component in other organism during symbiotic interaction 0.996982 52185 modification of structure of other organism during symbiotic interaction 0.996982 52332 modification by organism of cell membrane in other organism during symbiotic interaction 0.996982 52331 hemolysis of cells in other organism during symbiotic interaction 0.996982 1907 killing by symbiont of host cells 0.996982 1908 killing of cells of another organism 0.996982 1901 cytolysis of cells of another organism 0.996982 1897 cytolysis by symbiont of host cells 0.996982 44179 hemolysis of cells in other organism 0.996982 44004 disruption by symbiont of host cells 0.996982 19836 hemolysis by symbiont of host erythrocytes 0.996982 51883 killing of cells in other organism during symbiotic interaction 0.996982 51818 disruption of cells of other organism during symbiotic interaction 0.996982 51801 cytolysis of cells in other organism during symbiotic interaction 0.996982 51715 cytolysis of cells of another organism 0.996982 10613 positive regulation of cardiac muscle hypertrophy 0.996982 10615 positive regulation of cardiac muscle adaptation 0.996982 14742 positive regulation of muscle hypertrophy 0.996982 14744 positive regulation of muscle adaptation 0.996982 21988 olfactory lobe development 0.996958 21990 neural plate formation 0.996958 50809 diazepam binding 0.996958 19249 lactate biosynthetic process 0.996958 19244 lactate biosynthetic process from pyruvate 0.996958 43302 positive regulation of leukocyte degranulation 0.996933 43306 positive regulation of mast cell degranulation 0.996933 34040 lipid-transporting ATPase activity 0.996910 34041 sterol-transporting ATPase activity 0.996910 9726 detection of endogenous stimulus 0.996910 9720 detection of hormone stimulus 0.996910 34437 glycoprotein transporter activity 0.996910 34436 glycoprotein transport 0.996910 42069 regulation of catecholamine metabolic process 0.996901 42053 regulation of dopamine metabolic process 0.996901 2035 brain renin-angiotensin system 0.996885 51387 negative regulation of nerve growth factor receptor signaling pathway 0.996885 10872 regulation of cholesterol esterification 0.996866 9441 glycolate metabolic process 0.996861 14834 satellite cell maintenance involved in skeletal muscle regeneration 0.996861 14904 myotube cell development 0.996861 33292 T-tubule organization 0.996813 60299 negative regulation of sarcomere organization 0.996813 60306 regulation of membrane repolarization 0.996813 60307 regulation of ventricular cardiomyocyte membrane repolarization 0.996813 43932 ossification involved in bone remodeling 0.996813 40037 negative regulation of fibroblast growth factor receptor signaling pathway 0.996813 10612 regulation of cardiac muscle adaptation 0.996812 10611 regulation of cardiac muscle hypertrophy 0.996812 14743 regulation of muscle hypertrophy 0.996812 10873 positive regulation of cholesterol esterification 0.996812 43366 beta selection 0.996765 45818 negative regulation of glycogen catabolic process 0.996740 5981 regulation of glycogen catabolic process 0.996740 6059 hexitol metabolic process 0.996716 6062 sorbitol catabolic process 0.996716 6060 sorbitol metabolic process 0.996716 3939 L-iditol 2-dehydrogenase activity 0.996716 51160 L-xylitol catabolic process 0.996716 51164 L-xylitol metabolic process 0.996716 46370 fructose biosynthetic process 0.996716 19527 pentitol catabolic process 0.996716 19407 hexitol catabolic process 0.996716 19519 pentitol metabolic process 0.996716 10660 regulation of muscle cell apoptosis 0.996716 43502 regulation of muscle adaptation 0.996688 18158 protein amino acid oxidation 0.996668 10269 response to selenium ion 0.996668 48773 erythrophore differentiation 0.996620 55093 response to hyperoxia 0.996620 1315 age-dependent response to reactive oxygen species 0.996620 3069 vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure 0.996620 10260 organ senescence 0.996620 4731 purine-nucleoside phosphorylase activity 0.996572 6148 inosine catabolic process 0.996572 6736 NAD biosynthetic process 0.996572 34356 NAD biosynthesis via nicotinamide riboside salvage pathway 0.996572 45401 positive regulation of interleukin-3 biosynthetic process 0.996547 45399 regulation of interleukin-3 biosynthetic process 0.996547 32672 regulation of interleukin-3 production 0.996547 70653 high-density lipoprotein receptor binding 0.996523 10903 negative regulation of very-low-density lipoprotein particle remodeling 0.996523 9133 nucleoside diphosphate biosynthetic process 0.996499 9189 deoxyribonucleoside diphosphate biosynthetic process 0.996499 32488 Cdc42 protein signal transduction 0.996487 42163 interleukin-12 beta subunit binding 0.996475 42520 positive regulation of tyrosine phosphorylation of Stat4 protein 0.996475 42519 regulation of tyrosine phosphorylation of Stat4 protein 0.996475 43514 interleukin-12 complex 0.996475 19972 interleukin-12 binding 0.996475 60228 phosphatidylcholine-sterol O-acyltransferase activator activity 0.996474 2707 negative regulation of lymphocyte mediated immunity 0.996462 2704 negative regulation of leukocyte mediated immunity 0.996462 2323 natural killer cell activation during immune response 0.996427 42164 interleukin-12 alpha subunit binding 0.996427 34378 chylomicron assembly 0.996378 48148 behavioral response to cocaine 0.996364 32976 release of matrix enzymes from mitochondria 0.996330 46674 induction of retinal programmed cell death 0.996330 46670 positive regulation of retinal cell programmed cell death 0.996330 5757 mitochondrial permeability transition pore complex 0.996330 31937 positive regulation of chromatin silencing 0.996234 43518 negative regulation of DNA damage response, signal transduction by p53 class mediator 0.996234 6343 establishment of chromatin silencing 0.996234 6089 lactate metabolic process 0.996233 34391 regulation of smooth muscle cell apoptosis 0.996223 10727 negative regulation of hydrogen peroxide metabolic process 0.996185 16236 macroautophagy 0.996185 60765 regulation of androgen receptor signaling pathway 0.996185 2905 regulation of mature B cell apoptosis 0.996161 2906 negative regulation of mature B cell apoptosis 0.996161 9265 2'-deoxyribonucleotide biosynthetic process 0.996153 45136 development of secondary sexual characteristics 0.996153 70077 histone arginine demethylation 0.996137 70079 histone H4-R3 demethylation 0.996137 70078 histone H3-R2 demethylation 0.996137 33746 histone demethylase activity (H3-R2 specific) 0.996137 33749 histone demethylase activity (H4-R3 specific) 0.996137 18395 peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine 0.996137 17185 peptidyl-lysine hydroxylation 0.996137 60332 positive regulation of response to interferon-gamma 0.996089 60330 regulation of response to interferon-gamma 0.996089 60335 positive regulation of interferon-gamma-mediated signaling pathway 0.996089 15886 heme transport 0.996089 33239 negative regulation of cellular amine metabolic process 0.996088 45409 negative regulation of interleukin-6 biosynthetic process 0.996076 32922 circadian regulation of gene expression 0.996024 2884 negative regulation of hypersensitivity 0.995992 2865 negative regulation of acute inflammatory response to antigenic stimulus 0.995992 1808 negative regulation of type IV hypersensitivity 0.995992 1807 regulation of type IV hypersensitivity 0.995992 34363 intermediate-density lipoprotein particle 0.995992 45986 negative regulation of smooth muscle contraction 0.995975 45940 positive regulation of steroid metabolic process 0.995974 55106 ubiquitin-protein ligase regulator activity 0.995944 55105 ubiquitin-protein ligase inhibitor activity 0.995944 55104 ligase inhibitor activity 0.995944 55103 ligase regulator activity 0.995944 32691 negative regulation of interleukin-1 beta production 0.995943 32765 positive regulation of mast cell cytokine production 0.995919 51988 regulation of attachment of spindle microtubules to kinetochore 0.995896 44413 avoidance of host defenses 0.995895 44415 evasion or tolerance of host defenses 0.995895 51832 avoidance of defenses of other organism during symbiotic interaction 0.995895 51834 evasion or tolerance of defenses of other organism during symbiotic interaction 0.995895 19049 evasion of host defenses by virus 0.995895 32661 regulation of interleukin-18 production 0.995871 42414 epinephrine metabolic process 0.995871 70123 transforming growth factor beta receptor activity, type III 0.995847 60318 definitive erythrocyte differentiation 0.995847 32354 response to follicle-stimulating hormone stimulus 0.995847 34694 response to prostaglandin stimulus 0.995847 34695 response to prostaglandin E stimulus 0.995847 34699 response to luteinizing hormone stimulus 0.995847 34698 response to gonadotropin stimulus 0.995847 70874 negative regulation of glycogen metabolic process 0.995815 70431 nucleotide-binding oligomerization domain containing 2 signaling pathway 0.995799 70427 nucleotide-binding oligomerization domain containing 1 signaling pathway 0.995799 70423 nucleotide-binding oligomerization domain containing signaling pathway 0.995799 45746 negative regulation of Notch signaling pathway 0.995799 34142 toll-like receptor 4 signaling pathway 0.995799 42220 response to cocaine 0.995792 14073 response to tropane 0.995792 34983 peptidyl-lysine deacetylation 0.995766 10656 negative regulation of muscle cell apoptosis 0.995734 46031 ADP metabolic process 0.995726 9135 purine nucleoside diphosphate metabolic process 0.995726 9179 purine ribonucleoside diphosphate metabolic process 0.995726 55119 relaxation of cardiac muscle 0.995702 55118 negative regulation of cardiac muscle contraction 0.995702 42118 endothelial cell activation 0.995702 14740 negative regulation of muscle hyperplasia 0.995654 14738 regulation of muscle hyperplasia 0.995654 70698 type I activin receptor binding 0.995606 70697 activin receptor binding 0.995606 70696 transmembrane receptor protein serine/threonine kinase binding 0.995606 10991 negative regulation of SMAD protein complex assembly 0.995606 10990 regulation of SMAD protein complex assembly 0.995606 2645 positive regulation of tolerance induction 0.995581 2643 regulation of tolerance induction 0.995581 90075 relaxation of muscle 0.995576 7195 inhibition of adenylate cyclase activity by dopamine receptor signaling pathway 0.995573 70314 G1 to G0 transition 0.995557 70564 positive regulation of vitamin D receptor signaling pathway 0.995557 70562 regulation of vitamin D receptor signaling pathway 0.995557 4498 calcidiol 1-monooxygenase activity 0.995557 42368 vitamin D biosynthetic process 0.995557 2710 negative regulation of T cell mediated immunity 0.995541 60584 regulation of prostaglandin-endoperoxide synthase activity 0.995533 60585 positive regulation of prostaglandin-endoperoxidase synthase activity 0.995533 60438 trachea development 0.995509 60433 bronchus development 0.995509 60503 bud dilation involved in lung branching 0.995509 60502 epithelial cell proliferation involved in lung morphogenesis 0.995509 60087 relaxation of vascular smooth muscle 0.995496 70574 cadmium ion transmembrane transport 0.995485 45082 positive regulation of interleukin-10 biosynthetic process 0.995485 45074 regulation of interleukin-10 biosynthetic process 0.995485 15691 cadmium ion transport 0.995485 46544 development of secondary male sexual characteristics 0.995437 46543 development of secondary female sexual characteristics 0.995437 2863 positive regulation of inflammatory response to antigenic stimulus 0.995436 2681 somatic recombination of T cell receptor gene segments 0.995413 33153 T cell receptor V(D)J recombination 0.995413 2568 somatic diversification of T cell receptor genes 0.995413 51102 DNA ligation during DNA recombination 0.995413 30828 positive regulation of cGMP biosynthetic process 0.995396 30825 positive regulation of cGMP metabolic process 0.995396 46135 pyrimidine nucleoside catabolic process 0.995388 15774 polysaccharide transport 0.995388 15920 lipopolysaccharide transport 0.995388 46073 dTMP metabolic process 0.995364 4799 thymidylate synthase activity 0.995364 9157 deoxyribonucleoside monophosphate biosynthetic process 0.995364 9176 pyrimidine deoxyribonucleoside monophosphate metabolic process 0.995364 9177 pyrimidine deoxyribonucleoside monophosphate biosynthetic process 0.995364 6231 dTMP biosynthetic process 0.995364 42083 5,10-methylenetetrahydrofolate-dependent methyltransferase activity 0.995364 16608 growth hormone-releasing hormone activity 0.995364 45938 positive regulation of circadian sleep/wake cycle, sleep 0.995364 31716 calcitonin receptor binding 0.995316 1984 vasodilation of artery involved in baroreceptor response to increased systemic arterial blood pressure 0.995316 31284 positive regulation of guanylate cyclase activity 0.995292 34452 dynactin binding 0.995292 42754 negative regulation of circadian rhythm 0.995292 51462 regulation of cortisol secretion 0.995292 51464 positive regulation of cortisol secretion 0.995292 42322 negative regulation of circadian sleep/wake cycle, REM sleep 0.995292 42321 negative regulation of circadian sleep/wake cycle, sleep 0.995292 70715 sodium-dependent organic cation transport 0.995268 52097 interspecies quorum sensing 0.995268 48874 homeostasis of number of cells in a free-living population 0.995268 52106 quorum sensing during interaction with host 0.995268 60730 regulation of intestinal epithelial structure maintenance 0.995268 60731 positive regulation of intestinal epithelial structure maintenance 0.995268 9372 quorum sensing 0.995268 32722 positive regulation of chemokine production 0.995226 21779 oligodendrocyte cell fate commitment 0.995219 60165 regulation of timing of subpallium neuron differentiation 0.995219 60163 subpallium neuron fate commitment 0.995219 7400 neuroblast fate determination 0.995219 8627 induction of apoptosis by ionic changes 0.995171 34237 protein kinase A regulatory subunit binding 0.995171 43924 suramin binding 0.995171 14808 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 0.995171 32301 MutSalpha complex 0.995147 32143 single thymine insertion binding 0.995147 2034 regulation of blood vessel size by renin-angiotensin 0.995123 1596 angiotensin type I receptor activity 0.995123 3072 renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure 0.995123 6642 triglyceride mobilization 0.995123 51097 negative regulation of helicase activity 0.995099 2019 regulation of renal output by angiotensin 0.995074 33866 nucleoside bisphosphate biosynthetic process 0.995026 34036 purine ribonucleoside bisphosphate biosynthetic process 0.995026 34033 purine nucleoside bisphosphate biosynthetic process 0.995026 34030 ribonucleoside bisphosphate biosynthetic process 0.995026 50428 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process 0.995026 32800 receptor biosynthetic process 0.995001 55099 response to high density lipoprotein stimulus 0.994978 9221 pyrimidine deoxyribonucleotide biosynthetic process 0.994978 32692 negative regulation of interleukin-1 production 0.994977 33238 regulation of cellular amine metabolic process 0.994976 42320 regulation of circadian sleep/wake cycle, REM sleep 0.994941 34188 apolipoprotein A-I receptor activity 0.994930 30226 apolipoprotein receptor activity 0.994930 2880 regulation of chronic inflammatory response to non-antigenic stimulus 0.994881 2882 positive regulation of chronic inflammatory response to non-antigenic stimulus 0.994881 45950 negative regulation of mitotic recombination 0.994833 51782 negative regulation of cell division 0.994833 14911 positive regulation of smooth muscle cell migration 0.994817 47783 corticosterone 18-monooxygenase activity 0.994785 14745 negative regulation of muscle adaptation 0.994784 2016 regulation of blood volume by renin-angiotensin 0.994768 45820 negative regulation of glycolysis 0.994737 14854 response to inactivity 0.994737 14877 response to muscle inactivity involved in regulation of muscle adaptation 0.994737 14870 response to muscle inactivity 0.994737 14894 response to denervation involved in regulation of muscle adaptation 0.994737 50650 chondroitin sulfate proteoglycan biosynthetic process 0.994736 34382 chylomicron remnant clearance 0.994726 48537 mucosal-associated lymphoid tissue development 0.994724 48541 Peyer's patch development 0.994724 34191 apolipoprotein A-I receptor binding 0.994688 50713 negative regulation of interleukin-1 beta secretion 0.994688 75136 response to host 0.994688 52200 response to host defenses 0.994688 52173 response to defenses of other organism during symbiotic interaction 0.994688 42756 drinking behavior 0.994664 30910 olfactory placode formation 0.994664 46814 virion attachment, binding of host cell surface coreceptor 0.994640 19063 virion penetration into host cell 0.994640 19064 viral envelope fusion with host membrane 0.994640 45080 positive regulation of chemokine biosynthetic process 0.994597 4340 glucokinase activity 0.994592 34287 detection of monosaccharide stimulus 0.994592 9730 detection of carbohydrate stimulus 0.994592 9732 detection of hexose stimulus 0.994592 51594 detection of glucose 0.994592 2032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin 0.994591 51380 norepinephrine binding 0.994591 22601 menstrual cycle phase 0.994591 48554 positive regulation of metalloenzyme activity 0.994559 48552 regulation of metalloenzyme activity 0.994559 5896 interleukin-6 receptor complex 0.994559 46072 dTDP metabolic process 0.994543 4798 thymidylate kinase activity 0.994543 9139 pyrimidine nucleoside diphosphate biosynthetic process 0.994543 9196 pyrimidine deoxyribonucleoside diphosphate metabolic process 0.994543 9197 pyrimidine deoxyribonucleoside diphosphate biosynthetic process 0.994543 6233 dTDP biosynthetic process 0.994543 10734 negative regulation of protein amino acid glutathionylation 0.994495 10732 regulation of protein amino acid glutathionylation 0.994495 6010 glucose 6-phosphate utilization 0.994495 46390 ribose phosphate biosynthetic process 0.994495 19693 ribose phosphate metabolic process 0.994495 19302 D-ribose biosynthetic process 0.994495 1820 serotonin secretion 0.994495 33875 ribonucleoside bisphosphate metabolic process 0.994471 34035 purine ribonucleoside bisphosphate metabolic process 0.994471 34032 purine nucleoside bisphosphate metabolic process 0.994471 50427 3'-phosphoadenosine 5'-phosphosulfate metabolic process 0.994471 10893 positive regulation of steroid biosynthetic process 0.994465 1575 globoside metabolic process 0.994447 46 autophagic vacuole fusion 0.994447 43654 recognition of apoptotic cell 0.994447 10616 negative regulation of cardiac muscle adaptation 0.994446 10614 negative regulation of cardiac muscle hypertrophy 0.994446 2440 production of molecular mediator of immune response 0.994446 14741 negative regulation of muscle hypertrophy 0.994446 2883 regulation of hypersensitivity 0.994446 2864 regulation of acute inflammatory response to antigenic stimulus 0.994446 33005 positive regulation of mast cell activation 0.994437 34380 high-density lipoprotein particle assembly 0.994417 45819 positive regulation of glycogen catabolic process 0.994399 1987 vasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressure 0.994399 2664 regulation of T cell tolerance induction 0.994374 2666 positive regulation of T cell tolerance induction 0.994374 33599 regulation of mammary gland epithelial cell proliferation 0.994374 2086 diaphragm contraction 0.994350 10802 respiratory system process 0.994350 43181 vacuolar sequestering 0.994350 5985 sucrose metabolic process 0.994350 23 maltose metabolic process 0.994350 3011 involuntary skeletal muscle contraction 0.994350 15826 threonine transport 0.994302 15195 L-threonine transmembrane transporter activity 0.994302 34590 L-hydroxyproline transmembrane transporter activity 0.994302 34589 hydroxyproline transport 0.994302 9138 pyrimidine nucleoside diphosphate metabolic process 0.994302 19730 antimicrobial humoral response 0.994302 60556 regulation of vitamin D biosynthetic process 0.994301 70231 T cell apoptosis 0.994269 6924 activation-induced cell death of T cells 0.994269 10933 positive regulation of macrophage tolerance induction 0.994254 10936 negative regulation of macrophage cytokine production 0.994254 10935 regulation of macrophage cytokine production 0.994254 10932 regulation of macrophage tolerance induction 0.994254 51590 positive regulation of neurotransmitter transport 0.994253 6300 mismatch repair 0.994205 710 meiotic mismatch repair 0.994205 10899 regulation of phosphatidylcholine catabolic process 0.994157 10900 negative regulation of phosphatidylcholine catabolic process 0.994157 2385 mucosal immune response 0.994157 2227 innate immune response in mucosa 0.994157 51817 modification of morphology or physiology of other organism during symbiotic interaction 0.994120 32804 negative regulation of low-density lipoprotein receptor catabolic process 0.994109 32903 regulation of nerve growth factor production 0.994109 32900 negative regulation of neurotrophin production 0.994109 32904 negative regulation of nerve growth factor production 0.994109 32911 negative regulation of transforming growth factor-beta1 production 0.994109 32899 regulation of neurotrophin production 0.994109 55094 response to lipoprotein stimulus 0.994084 34392 negative regulation of smooth muscle cell apoptosis 0.994084 46130 purine ribonucleoside catabolic process 0.994076 6152 purine nucleoside catabolic process 0.994076 2033 vasodilation by angiotensin involved in regulation of systemic arterial blood pressure 0.994061 1991 regulation of systemic arterial blood pressure by circulatory renin-angiotensin 0.994061 43552 positive regulation of phosphoinositide 3-kinase activity 0.994060 43551 regulation of phosphoinositide 3-kinase activity 0.994060 42753 positive regulation of circadian rhythm 0.994060 46048 UDP metabolic process 0.994012 9140 pyrimidine nucleoside diphosphate catabolic process 0.994012 9193 pyrimidine ribonucleoside diphosphate metabolic process 0.994012 9195 pyrimidine ribonucleoside diphosphate catabolic process 0.994012 9222 pyrimidine ribonucleotide catabolic process 0.994012 45134 uridine-diphosphatase activity 0.994012 6256 UDP catabolic process 0.994012 10755 regulation of plasminogen activation 0.993988 31904 endosome lumen 0.993964 34360 chylomicron remnant 0.993964 34359 mature chylomicron 0.993964 34384 high-density lipoprotein particle clearance 0.993963 60696 regulation of phospholipid catabolic process 0.993940 51968 positive regulation of synaptic transmission, glutamatergic 0.993940 2309 T cell proliferation during immune response 0.993916 31657 regulation of cyclin-dependent protein kinase activity during G1/S 0.993899 31659 positive regulation of cyclin-dependent protein kinase activity during G1/S 0.993899 55089 fatty acid homeostasis 0.993891 2885 positive regulation of hypersensitivity 0.993883 2866 positive regulation of acute inflammatory response to antigenic stimulus 0.993883 2903 negative regulation of B cell apoptosis 0.993879 3081 regulation of systemic arterial blood pressure by renin-angiotensin 0.993876 45719 negative regulation of glycogen biosynthetic process 0.993867 46639 negative regulation of alpha-beta T cell differentiation 0.993851 2891 positive regulation of immunoglobulin mediated immune response 0.993831 2714 positive regulation of B cell mediated immunity 0.993831 43134 regulation of hindgut contraction 0.993819 1616 growth hormone secretagogue receptor activity 0.993819 42482 positive regulation of odontogenesis 0.993771 42488 positive regulation of odontogenesis of dentine-containing tooth 0.993771 42485 positive regulation of odontogenesis 0.993771 51799 negative regulation of hair follicle development 0.993771 70483 detection of hypoxia 0.993723 48702 embryonic neurocranium morphogenesis 0.993723 70508 cholesterol import 0.993722 2251 organ or tissue specific immune response 0.993683 60697 positive regulation of phospholipid catabolic process 0.993674 45588 positive regulation of gamma-delta T cell differentiation 0.993637 45586 regulation of gamma-delta T cell differentiation 0.993637 46643 regulation of gamma-delta T cell activation 0.993637 46645 positive regulation of gamma-delta T cell activation 0.993637 70186 growth hormone activity 0.993626 10535 positive regulation of activation of JAK2 kinase activity 0.993626 10536 positive regulation of activation of Janus kinase activity 0.993626 10533 regulation of activation of Janus kinase activity 0.993626 10534 regulation of activation of JAK2 kinase activity 0.993626 46084 adenine biosynthetic process 0.993626 46083 adenine metabolic process 0.993626 6168 adenine salvage 0.993626 43096 purine base salvage 0.993626 45910 negative regulation of DNA recombination 0.993605 60558 regulation of calcidiol 1-monooxygenase activity 0.993603 51386 regulation of nerve growth factor receptor signaling pathway 0.993593 21897 forebrain astrocyte development 0.993578 21510 spinal cord development 0.993578 42454 ribonucleoside catabolic process 0.993553 46856 phosphoinositide dephosphorylation 0.993529 46855 inositol phosphate dephosphorylation 0.993529 51800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity 0.993529 51717 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity 0.993529 9048 dosage compensation, by inactivation of X chromosome 0.993481 46606 negative regulation of centrosome cycle 0.993481 46600 negative regulation of centriole replication 0.993481 32803 regulation of low-density lipoprotein receptor catabolic process 0.993464 6549 isoleucine metabolic process 0.993448 46449 creatinine metabolic process 0.993448 34241 positive regulation of macrophage fusion 0.993433 34239 regulation of macrophage fusion 0.993433 60142 regulation of syncytium formation by plasma membrane fusion 0.993433 60143 positive regulation of syncytium formation by plasma membrane fusion 0.993433 60164 regulation of timing of neuron differentiation 0.993432 55117 regulation of cardiac muscle contraction 0.993396 33484 nitric oxide homeostasis 0.993385 30656 regulation of vitamin metabolic process 0.993383 10677 negative regulation of cellular carbohydrate metabolic process 0.993348 45912 negative regulation of carbohydrate metabolic process 0.993348 45823 positive regulation of heart contraction 0.993338 21670 lateral ventricle development 0.993336 21678 third ventricle development 0.993336 21592 fourth ventricle development 0.993336 50711 negative regulation of interleukin-1 secretion 0.993336 32344 regulation of aldosterone metabolic process 0.993312 31627 telomeric loop formation 0.993288 1304 progressive alteration of chromatin during replicative cell aging 0.993288 1301 progressive alteration of chromatin during cell aging 0.993288 1309 age-dependent telomere shortening 0.993288 45726 positive regulation of integrin biosynthetic process 0.993263 10523 negative regulation of calcium ion transport into cytosol 0.993251 3300 cardiac muscle hypertrophy 0.993240 3299 muscle hypertrophy in response to stress 0.993240 14887 cardiac muscle adaptation 0.993240 14888 striated muscle adaptation 0.993240 14897 striated muscle hypertrophy 0.993240 14898 cardiac muscle hypertrophy in response to stress 0.993240 4915 interleukin-6 receptor activity 0.993239 19981 interleukin-6 binding 0.993239 34190 apolipoprotein receptor binding 0.993223 42416 dopamine biosynthetic process 0.993202 46294 formaldehyde catabolic process 0.993191 18119 peptidyl-cysteine S-nitrosylation 0.993191 18467 formaldehyde dehydrogenase activity 0.993191 17014 protein amino acid nitrosylation 0.993191 51903 S-(hydroxymethyl)glutathione dehydrogenase activity 0.993191 33612 receptor serine/threonine kinase binding 0.993167 45713 low-density lipoprotein receptor biosynthetic process 0.993143 55098 response to low-density lipoprotein stimulus 0.993143 32799 low-density lipoprotein receptor metabolic process 0.993143 51851 modification by host of symbiont morphology or physiology 0.993110 400 four-way junction DNA binding 0.993110 31223 auditory behavior 0.993095 9449 gamma-aminobutyric acid biosynthetic process 0.993095 5314 high-affinity glutamate transmembrane transporter activity 0.993095 7442 hindgut morphogenesis 0.993046 46032 ADP catabolic process 0.992998 9137 purine nucleoside diphosphate catabolic process 0.992998 9181 purine ribonucleoside diphosphate catabolic process 0.992998 46707 IDP metabolic process 0.992998 46709 IDP catabolic process 0.992998 10922 positive regulation of phosphatase activity 0.992997 10901 regulation of very-low-density lipoprotein particle remodeling 0.992968 45909 positive regulation of vasodilation 0.992953 70179 D-serine biosynthetic process 0.992950 70178 D-serine metabolic process 0.992950 18114 threonine racemase activity 0.992950 30378 serine racemase activity 0.992950 46437 D-amino acid biosynthetic process 0.992950 51963 regulation of synaptogenesis 0.992925 31302 intrinsic to endosome membrane 0.992902 10813 neuropeptide catabolic process 0.992902 10814 substance P catabolic process 0.992902 10816 calcitonin catabolic process 0.992902 34959 endothelin maturation 0.992902 48180 activin complex 0.992853 43509 activin A complex 0.992853 4952 dopamine receptor activity 0.992842 2384 hepatic immune response 0.992829 9185 ribonucleoside diphosphate metabolic process 0.992816 21540 corpus callosum morphogenesis 0.992805 235 astral microtubule 0.992805 31711 bradykinin receptor binding 0.992805 2377 immunoglobulin production 0.992805 16418 S-acetyltransferase activity 0.992805 51775 response to redox state 0.992788 43420 anthranilate metabolic process 0.992757 18874 benzoate metabolic process 0.992757 30429 kynureninase activity 0.992757 34516 response to vitamin B6 0.992757 6925 inflammatory cell apoptosis 0.992732 70506 high-density lipoprotein receptor activity 0.992708 16233 telomere capping 0.992660 60383 positive regulation of DNA strand elongation 0.992660 60382 regulation of DNA strand elongation 0.992660 2892 regulation of type II hypersensitivity 0.992636 2894 positive regulation of type II hypersensitivity 0.992636 2888 positive regulation of myeloid leukocyte mediated immunity 0.992636 1796 regulation of type IIa hypersensitivity 0.992636 1798 positive regulation of type IIa hypersensitivity 0.992636 51000 positive regulation of nitric-oxide synthase activity 0.992615 70283 radical SAM enzyme activity 0.992612 16992 lipoate synthase activity 0.992612 16979 lipoate-protein ligase activity 0.992612 16978 lipoate-protein ligase activity 0.992612 8916 lipoate-protein ligase activity 0.992612 17140 lipoic acid synthase activity 0.992612 50651 dermatan sulfate proteoglycan biosynthetic process 0.992564 8955 peptidoglycan glycosyltransferase activity 0.992564 43237 laminin-1 binding 0.992547 2678 positive regulation of chronic inflammatory response 0.992539 2676 regulation of chronic inflammatory response 0.992539 10882 regulation of cardiac muscle contraction by calcium ion signaling 0.992539 10881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion 0.992539 33377 maintenance of protein location in T cell secretory granule 0.992515 33379 maintenance of protease location in T cell secretory granule 0.992515 33371 T cell secretory granule organization 0.992515 33370 maintenance of protein location in mast cell secretory granule 0.992515 33373 maintenance of protease location in mast cell secretory granule 0.992515 33382 maintenance of granzyme B location in T cell secretory granule 0.992515 30673 axolemma 0.992467 32589 neuron projection membrane 0.992467 15501 glutamate:sodium symporter activity 0.992467 50430 syntaxin-6 binding 0.992419 43002 negative regulation of Golgi to plasma membrane CFTR protein transport 0.992419 43004 cytoplasmic sequestering of CFTR protein 0.992419 42999 regulation of Golgi to plasma membrane CFTR protein transport 0.992419 42997 negative regulation of Golgi to plasma membrane protein transport 0.992419 42996 regulation of Golgi to plasma membrane protein transport 0.992419 42980 cystic fibrosis transmembrane conductance regulator binding 0.992419 45541 negative regulation of cholesterol biosynthetic process 0.992418 4511 tyrosine 3-monooxygenase activity 0.992370 6585 dopamine biosynthetic process from tyrosine 0.992370 42418 epinephrine biosynthetic process 0.992370 42421 norepinephrine biosynthetic process 0.992370 31342 negative regulation of cell killing 0.992322 1915 negative regulation of T cell mediated cytotoxicity 0.992322 1911 negative regulation of leukocyte mediated cytotoxicity 0.992322 35240 dopamine binding 0.992312 46013 regulation of T cell homeostatic proliferation 0.992298 48570 notochord morphogenesis 0.992226 60302 negative regulation of cytokine activity 0.992226 60300 regulation of cytokine activity 0.992226 46185 aldehyde catabolic process 0.992225 52572 response to host immune response 0.992177 52564 response to immune response of other organism during symbiotic interaction 0.992177 52565 response to defense-related host nitric oxide production 0.992177 52551 response to defense-related nitric oxide production by other organism during symbiotic interaction 0.992177 51788 response to misfolded protein 0.992177 60027 convergent extension involved in gastrulation 0.992153 60026 convergent extension 0.992153 5114 type II transforming growth factor beta receptor binding 0.992143 45366 regulation of interleukin-13 biosynthetic process 0.992129 45368 positive regulation of interleukin-13 biosynthetic process 0.992129 5718 nucleosome 0.992129 788 nuclear nucleosome 0.992129 10988 regulation of low-density lipoprotein particle clearance 0.992129 10989 negative regulation of low-density lipoprotein particle clearance 0.992129 21756 striatum development 0.992127 34205 beta-amyloid formation 0.992081 32689 negative regulation of interferon-gamma production 0.992068 33593 BRCA2-MAGE-D1 complex 0.992032 33595 response to genistein 0.992032 33600 negative regulation of mammary gland epithelial cell proliferation 0.992032 9996 negative regulation of cell fate specification 0.991984 42659 regulation of cell fate specification 0.991984 42660 positive regulation of cell fate specification 0.991984 10459 negative regulation of heart rate 0.991984 45751 negative regulation of Toll signaling pathway 0.991936 8592 regulation of Toll signaling pathway 0.991936 45381 regulation of interleukin-18 biosynthetic process 0.991936 46087 cytidine metabolic process 0.991839 46133 pyrimidine ribonucleoside catabolic process 0.991839 8655 pyrimidine salvage 0.991839 6216 cytidine catabolic process 0.991839 9972 cytidine deamination 0.991839 33034 positive regulation of myeloid cell apoptosis 0.991839 1306 age-dependent response to oxidative stress 0.991815 7571 age-dependent general metabolic decline 0.991815 45591 positive regulation of regulatory T cell differentiation 0.991791 32831 positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation 0.991791 32829 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation 0.991791 42092 T-helper 2 type immune response 0.991790 2024 diet induced thermogenesis 0.991774 2025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure 0.991774 4939 beta-adrenergic receptor activity 0.991774 45835 negative regulation of meiosis 0.991743 42508 tyrosine phosphorylation of Stat1 protein 0.991743 42503 tyrosine phosphorylation of Stat3 protein 0.991743 42506 tyrosine phosphorylation of Stat5 protein 0.991743 5147 oncostatin-M receptor binding 0.991743 70163 regulation of adiponectin secretion 0.991742 1768 establishment of T cell polarity 0.991742 1767 establishment of lymphocyte polarity 0.991742 70821 tertiary granule membrane 0.991694 55073 cadmium ion homeostasis 0.991694 55076 transition metal ion homeostasis 0.991694 6876 cellular cadmium ion homeostasis 0.991694 51139 metal ion:hydrogen antiporter activity 0.991694 46916 cellular transition metal ion homeostasis 0.991694 45542 positive regulation of cholesterol biosynthetic process 0.991670 2836 positive regulation of response to tumor cell 0.991661 2834 regulation of response to tumor cell 0.991661 2833 positive regulation of response to biotic stimulus 0.991661 2839 positive regulation of immune response to tumor cell 0.991661 2837 regulation of immune response to tumor cell 0.991661 3058 hormonal regulation of the force of heart contraction 0.991646 10742 macrophage derived foam cell differentiation 0.991629 90077 foam cell differentiation 0.991629 3100 regulation of systemic arterial blood pressure by endothelin 0.991616 51856 adhesion to symbiont 0.991613 51825 adhesion to other organism during symbiotic interaction 0.991613 21558 trochlear nerve development 0.991598 21557 oculomotor nerve development 0.991598 32909 regulation of transforming growth factor-beta2 production 0.991585 35280 miRNA loading onto RISC involved in gene silencing by miRNA 0.991550 32770 positive regulation of monooxygenase activity 0.991505 31770 growth hormone-releasing hormone receptor binding 0.991501 46005 positive regulation of circadian sleep/wake cycle, REM sleep 0.991501 43570 maintenance of DNA repeat elements 0.991500 32356 oxidized DNA binding 0.991500 32357 oxidized purine DNA binding 0.991500 32137 guanine/thymine mispair binding 0.991500 32134 mispaired DNA binding 0.991500 32142 single guanine insertion binding 0.991500 34109 homotypic cell-cell adhesion 0.991488 48715 negative regulation of oligodendrocyte differentiation 0.991468 2698 negative regulation of immune effector process 0.991453 3934 GTP cyclohydrolase I activity 0.991453 3933 GTP cyclohydrolase activity 0.991453 46654 tetrahydrofolate biosynthetic process 0.991453 42362 fat-soluble vitamin biosynthetic process 0.991453 9073 aromatic amino acid family biosynthetic process 0.991405 9095 aromatic amino acid family biosynthetic process, prephenate pathway 0.991405 16089 aromatic amino acid family biosynthetic process 0.991405 6571 tyrosine biosynthetic process 0.991405 46417 chorismate metabolic process 0.991405 10840 regulation of circadian sleep/wake cycle, wakefulness 0.991356 10841 positive regulation of circadian sleep/wake cycle, wakefulness 0.991356 2248 connective tissue replacement during inflammatory response 0.991356 48178 negative regulation of hepatocyte growth factor biosynthetic process 0.991308 48176 regulation of hepatocyte growth factor biosynthetic process 0.991308 32646 regulation of hepatocyte growth factor production 0.991308 46789 host cell surface receptor binding 0.991308 46812 host cell surface binding 0.991308 34713 type I transforming growth factor beta receptor binding 0.991278 34197 triglyceride transport 0.991260 34196 acylglycerol transport 0.991260 31297 replication fork processing 0.991235 9378 four-way junction helicase activity 0.991235 6064 glucuronate catabolic process 0.991212 47939 L-glucuronate reductase activity 0.991212 42839 D-glucuronate metabolic process 0.991212 42840 D-glucuronate catabolic process 0.991212 19853 L-ascorbic acid biosynthetic process 0.991212 51880 G-quadruplex DNA binding 0.991179 1976 neurological system process involved in regulation of systemic arterial blood pressure 0.991171 46533 negative regulation of photoreceptor cell differentiation 0.991163 7440 foregut morphogenesis 0.991163 10485 H4 histone acetyltransferase activity 0.991115 4404 histone acetyltransferase activity 0.991115 4405 histone acetyltransferase activity 0.991115 4403 histone acetyltransferase activity 0.991115 43166 histone acetyltransferase activity 0.991115 46971 histone acetyltransferase activity 0.991115 10956 negative regulation of calcidiol 1-monooxygenase activity 0.991098 70612 histone methyltransferase activity (H2A-R3 specific) 0.991067 70611 histone methyltransferase activity (H3-R2 specific) 0.991067 10894 negative regulation of steroid biosynthetic process 0.991036 45939 negative regulation of steroid metabolic process 0.991036 31699 beta-3 adrenergic receptor binding 0.991018 15052 beta3-adrenergic receptor activity 0.991018 43371 negative regulation of CD4-positive, alpha beta T cell differentiation 0.991018 45629 negative regulation of T-helper 2 cell differentiation 0.991018 45623 negative regulation of T-helper cell differentiation 0.991018 1921 positive regulation of receptor recycling 0.991018 30432 peristalsis 0.991005 32513 negative regulation of protein phosphatase type 2B activity 0.990994 32512 regulation of protein phosphatase type 2B activity 0.990994 70363 mitochondrial light strand promoter sense binding 0.990970 70362 mitochondrial heavy strand promoter anti-sense binding 0.990970 70364 mitochondrial heavy strand promoter sense binding 0.990970 70361 mitochondrial light strand promoter anti-sense binding 0.990970 70407 oxidation-dependent protein catabolic process 0.990970 32892 positive regulation of organic acid transport 0.990969 15866 ADP transport 0.990922 9191 ribonucleoside diphosphate catabolic process 0.990905 10878 cholesterol storage 0.990874 30548 acetylcholine receptor regulator activity 0.990873 10460 positive regulation of heart rate 0.990843 10722 regulation of ferrochelatase activity 0.990825 34986 iron chaperone activity 0.990825 21776 smoothened signaling pathway involved in spinal cord motor neuron cell fate specification 0.990777 21543 pallium development 0.990777 48755 branching morphogenesis of a nerve 0.990777 45060 negative thymic T cell selection 0.990776 3099 positive regulation of the force of heart contraction by chemical signal 0.990744 31338 regulation of vesicle fusion 0.990729 31630 regulation of synaptic vesicle fusion to presynaptic membrane 0.990729 48790 maintenance of presynaptic active zone structure 0.990729 50975 sensory perception of touch 0.990729 51602 response to electrical stimulus 0.990729 33860 regulation of NAD(P)H oxidase activity 0.990655 51584 regulation of dopamine uptake 0.990640 51580 regulation of neurotransmitter uptake 0.990640 51940 regulation of catecholamine uptake during transmission of nerve impulse 0.990640 2074 extraocular skeletal muscle development 0.990632 60014 granulosa cell differentiation 0.990632 30237 female sex determination 0.990632 42703 menstruation 0.990632 19101 female somatic sex determination 0.990632 2502 peptide antigen assembly with MHC class I protein complex 0.990584 2501 peptide antigen assembly with MHC protein complex 0.990584 32300 mismatch repair complex 0.990558 2727 regulation of natural killer cell cytokine production 0.990536 2729 positive regulation of natural killer cell cytokine production 0.990536 32825 positive regulation of natural killer cell differentiation 0.990536 32823 regulation of natural killer cell differentiation 0.990536 32796 uropod organization 0.990535 10544 negative regulation of platelet activation 0.990534 32812 positive regulation of epinephrine secretion 0.990487 14060 regulation of epinephrine secretion 0.990487 45402 regulation of interleukin-4 biosynthetic process 0.990463 45404 positive regulation of interleukin-4 biosynthetic process 0.990463 60218 hemopoietic stem cell differentiation 0.990439 1771 formation of immunological synapse 0.990391 43304 regulation of mast cell degranulation 0.990374 50755 chemokine metabolic process 0.990342 42231 interleukin-13 biosynthetic process 0.990342 42253 granulocyte macrophage colony-stimulating factor biosynthetic process 0.990342 42033 chemokine biosynthetic process 0.990342 42095 interferon-gamma biosynthetic process 0.990342 31240 external side of cell outer membrane 0.990294 2554 serotonin secretion by platelet 0.990294 2442 serotonin secretion during acute inflammatory response 0.990294 3056 regulation of vascular smooth muscle contraction 0.990294 2808 regulation of antibacterial peptide biosynthetic process 0.990294 2807 positive regulation of antimicrobial peptide biosynthetic process 0.990294 2805 regulation of antimicrobial peptide biosynthetic process 0.990294 2816 regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria 0.990294 2786 regulation of antibacterial peptide production 0.990294 2784 regulation of antimicrobial peptide production 0.990294 2759 regulation of antimicrobial humoral response 0.990294 6963 positive regulation of antibacterial peptide biosynthetic process 0.990294 6965 positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria 0.990294 45628 regulation of T-helper 2 cell differentiation 0.990281 10852 cyclase inhibitor activity 0.990246 30251 guanylate cyclase inhibitor activity 0.990246 35003 subapical complex 0.990246 30824 negative regulation of cGMP metabolic process 0.990246 30827 negative regulation of cGMP biosynthetic process 0.990246 1997 positive regulation of the force of heart contraction by epinephrine-norepinephrine 0.990245 1996 positive regulation of heart rate by epinephrine-norepinephrine 0.990245 33003 regulation of mast cell activation 0.990199 70075 tear secretion 0.990197 33173 calcineurin-NFAT signaling pathway 0.990197 51533 positive regulation of NFAT protein import into nucleus 0.990197 51532 regulation of NFAT protein import into nucleus 0.990197 10923 negative regulation of phosphatase activity 0.990196 70667 negative regulation of mast cell proliferation 0.990186 30889 negative regulation of B cell proliferation 0.990186 50995 negative regulation of lipid catabolic process 0.990164 2830 positive regulation of T-helper 2 type immune response 0.990149 70227 lymphocyte apoptosis 0.990147 32754 positive regulation of interleukin-5 production 0.990101 32736 positive regulation of interleukin-13 production 0.990101 32302 MutSbeta complex 0.990100 32181 dinucleotide repeat insertion binding 0.990100 44089 positive regulation of cellular component biogenesis 0.990100 51962 positive regulation of nervous system development 0.990100 51965 positive regulation of synaptogenesis 0.990100 43691 reverse cholesterol transport 0.990078 34987 immunoglobulin receptor binding 0.990053 34988 Fc-gamma receptor I complex binding 0.990053 34989 GTP-Ral binding 0.990053 51764 actin crosslink formation 0.990053 2005 angiotensin catabolic process in blood 0.990052 44266 multicellular organismal macromolecule catabolic process 0.990052 44268 multicellular organismal protein metabolic process 0.990052 44254 multicellular organismal protein catabolic process 0.990052 45513 interleukin-27 binding 0.990036 33315 meiotic cell cycle DNA replication checkpoint 0.990004 33313 meiotic cell cycle checkpoint 0.990004 42138 meiotic DNA double-strand break formation 0.990004 10032 meiotic chromosome condensation 0.990004 32278 positive regulation of gonadotropin secretion 0.989987 46881 positive regulation of follicle-stimulating hormone secretion 0.989987 6867 asparagine transport 0.989956 15817 histidine transport 0.989956 15182 L-asparagine transmembrane transporter activity 0.989956 5290 L-histidine transmembrane transporter activity 0.989956 32094 response to food 0.989930 2029 desensitization of G-protein coupled receptor protein signaling pathway 0.989923 22401 adaptation of signaling pathway 0.989923 1963 synaptic transmission, dopaminergic 0.989894 70922 small RNA loading onto RISC 0.989883 48852 diencephalon morphogenesis 0.989811 50973 detection of mechanical stimulus involved in equilibrioception 0.989811 21910 smoothened signaling pathway involved in ventral spinal cord patterning 0.989811 21775 smoothened signaling pathway involved in ventral spinal cord interneuron specification 0.989811 2294 CD4-positive, alpha-beta T cell differentiation during immune response 0.989773 2293 alpha-beta T cell differentiation during immune response 0.989773 2292 T cell differentiation during immune response 0.989773 42093 T-helper cell differentiation 0.989773 6961 antibacterial humoral response 0.989763 6960 antimicrobial humoral response 0.989763 43152 induction of bacterial agglutination 0.989763 19731 antibacterial humoral response 0.989763 19733 antibacterial humoral response 0.989763 19735 antimicrobial humoral response 0.989763 51409 response to nitrosative stress 0.989762 1914 regulation of T cell mediated cytotoxicity 0.989761 31705 bombesin receptor binding 0.989730 31708 endothelin B receptor binding 0.989730 32139 dinucleotide insertion or deletion binding 0.989730 19083 viral transcription 0.989715 19086 late viral mRNA transcription 0.989715 1956 positive regulation of neurotransmitter secretion 0.989714 7597 blood coagulation, intrinsic pathway 0.989714 34375 high-density lipoprotein particle remodeling 0.989701 50710 negative regulation of cytokine secretion 0.989669 48160 primary follicle stage, oogenesis 0.989666 42700 luteinizing hormone signaling pathway 0.989666 3051 angiotensin-mediated drinking behavior 0.989618 18992 germ-line sex determination 0.989570 60350 endochondral bone morphogenesis 0.989570 19100 male germ-line sex determination 0.989570 7542 primary sex determination, germ-line 0.989570 46125 pyrimidine deoxyribonucleoside metabolic process 0.989569 34673 inhibin-betaglycan-ActRII complex 0.989569 43456 regulation of pentose-phosphate shunt 0.989521 43455 regulation of secondary metabolic process 0.989521 34248 regulation of cellular amide metabolic process 0.989521 51193 regulation of cofactor metabolic process 0.989521 51196 regulation of coenzyme metabolic process 0.989521 10982 regulation of high-density lipoprotein particle clearance 0.989521 4008 copper-exporting ATPase activity 0.989497 43682 copper-transporting ATPase activity 0.989497 15677 copper ion import 0.989497 5378 copper ion transmembrane transporter activity 0.989497 5379 copper ion transmembrane transporter activity 0.989497 5380 copper ion transmembrane transporter activity 0.989497 16140 O-glycoside metabolic process 0.989473 16142 O-glycoside catabolic process 0.989473 6680 glucosylceramide catabolic process 0.989473 45630 positive regulation of T-helper 2 cell differentiation 0.989449 5329 dopamine transmembrane transporter activity 0.989425 5330 dopamine:sodium symporter activity 0.989425 10979 regulation of vitamin D 24-hydroxylase activity 0.989424 10980 positive regulation of vitamin D 24-hydroxylase activity 0.989424 70195 growth hormone receptor complex 0.989377 42524 negative regulation of tyrosine phosphorylation of Stat5 protein 0.989328 14010 Schwann cell proliferation 0.989328 14009 glial cell proliferation 0.989328 5899 insulin receptor complex 0.989311 46007 negative regulation of activated T cell proliferation 0.989304 34373 intermediate-density lipoprotein particle remodeling 0.989280 34638 phosphatidylcholine catabolic process 0.989280 43511 inhibin complex 0.989280 43512 inhibin A complex 0.989280 2902 regulation of B cell apoptosis 0.989277 33158 regulation of protein import into nucleus, translocation 0.989263 90031 positive regulation of steroid hormone biosynthetic process 0.989232 32346 positive regulation of aldosterone metabolic process 0.989232 32347 regulation of aldosterone biosynthetic process 0.989232 32349 positive regulation of aldosterone biosynthetic process 0.989232 5143 interleukin-12 receptor binding 0.989198 60632 regulation of microtubule-based movement 0.989191 43342 establishment or maintenance of neuroblast polarity 0.989183 43339 establishment or maintenance of neuroblast polarity 0.989183 45196 establishment or maintenance of neuroblast polarity 0.989183 45200 establishment of neuroblast polarity 0.989183 2857 positive regulation of natural killer cell mediated immune response to tumor cell 0.989181 2858 regulation of natural killer cell mediated cytotoxicity directed against tumor cell target 0.989181 2855 regulation of natural killer cell mediated immune response to tumor cell 0.989181 2860 positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target 0.989181 2055 adenine binding 0.989135 3999 adenine phosphoribosyltransferase activity 0.989135 6521 regulation of cellular amino acid metabolic process 0.989135 33570 transferrin transmembrane transporter activity 0.989087 22612 gland morphogenesis 0.989077 5030 neurotrophin receptor activity 0.989070 90218 positive regulation of lipid kinase activity 0.989054 34747 Axin-APC-beta-catenin-GSK3B complex 0.989054 70335 aspartate binding 0.989039 4088 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity 0.989039 4070 aspartate carbamoyltransferase activity 0.989039 4151 dihydroorotase activity 0.989039 4710 MAP/ERK kinase kinase activity 0.988990 70723 response to cholesterol 0.988989 51935 glutamate uptake during transmission of nerve impulse 0.988966 51933 amino acid uptake during transmission of nerve impulse 0.988966 45920 negative regulation of exocytosis 0.988941 2920 regulation of humoral immune response 0.988923 43626 PCNA complex 0.988894 30337 DNA polymerase processivity factor activity 0.988894 701 purine-specific mismatch base pair DNA N-glycosylase activity 0.988894 5652 nuclear lamina 0.988894 34979 NAD-dependent protein deacetylase activity 0.988893 17136 NAD-dependent histone deacetylase activity 0.988893 60044 negative regulation of cardiac muscle cell proliferation 0.988892 42903 tubulin deacetylase activity 0.988869 1916 positive regulation of T cell mediated cytotoxicity 0.988860 14821 phasic smooth muscle contraction 0.988860 2316 follicular B cell differentiation 0.988845 31935 regulation of chromatin silencing 0.988844 10580 activation of adenylate cyclase activity by G-protein signaling pathway 0.988844 60968 regulation of gene silencing 0.988844 7191 activation of adenylate cyclase activity by dopamine receptor signaling pathway 0.988844 70182 DNA polymerase binding 0.988821 46137 negative regulation of vitamin metabolic process 0.988821 10957 negative regulation of vitamin D biosynthetic process 0.988821 21517 ventral spinal cord development 0.988797 21508 floor plate formation 0.988797 34644 cellular response to UV 0.988796 60230 lipoprotein lipase activator activity 0.988780 70102 interleukin-6-mediated signaling pathway 0.988764 43017 positive regulation of lymphotoxin A biosynthetic process 0.988749 43016 regulation of lymphotoxin A biosynthetic process 0.988749 32681 regulation of lymphotoxin A production 0.988749 31642 negative regulation of myelination 0.988732 2639 positive regulation of immunoglobulin production 0.988724 48034 heme O biosynthetic process 0.988652 48033 heme o metabolic process 0.988652 8495 protoheme IX farnesyltransferase activity 0.988652 34445 negative regulation of plasma lipoprotein oxidation 0.988652 34444 regulation of plasma lipoprotein oxidation 0.988652 5915 zonula adherens 0.988628 70527 platelet aggregation 0.988619 6103 2-oxoglutarate metabolic process 0.988611 21660 rhombomere 3 formation 0.988604 21666 rhombomere 5 formation 0.988604 21594 rhombomere formation 0.988604 51156 glucose 6-phosphate metabolic process 0.988587 4086 carbamoyl-phosphate synthase activity 0.988579 6837 serotonin transport 0.988578 50929 induction of negative chemotaxis 0.988556 50924 positive regulation of negative chemotaxis 0.988556 50923 regulation of negative chemotaxis 0.988556 90130 tissue migration 0.988556 7509 mesoderm migration 0.988556 2861 regulation of inflammatory response to antigenic stimulus 0.988552 32642 regulation of chemokine production 0.988552 70119 ciliary neurotrophic factor binding 0.988507 9129 pyrimidine nucleoside monophosphate metabolic process 0.988482 9130 pyrimidine nucleoside monophosphate biosynthetic process 0.988482 70570 regulation of neuron projection regeneration 0.988459 70571 negative regulation of neuron projection regeneration 0.988459 48679 regulation of axon regeneration 0.988459 48681 negative regulation of axon regeneration 0.988459 10977 negative regulation of neuron projection development 0.988459 33077 T cell differentiation in the thymus 0.988417 4742 dihydrolipoyllysine-residue acetyltransferase activity 0.988411 45254 pyruvate dehydrogenase complex 0.988411 30523 dihydrolipoamide S-acyltransferase activity 0.988411 5967 mitochondrial pyruvate dehydrogenase complex 0.988411 9364 pyruvate dehydrogenase complex 0.988411 21555 midbrain-hindbrain boundary morphogenesis 0.988386 30264 nuclear fragmentation during apoptosis 0.988386 2538 production of arachidonic acid metabolites during acute inflammatory response 0.988363 2539 prostaglandin production during acute inflammatory response 0.988363 2532 production of molecular mediator of acute inflammatory response 0.988363 43651 linoleic acid metabolic process 0.988363 3869 4-nitrophenylphosphatase activity 0.988363 2360 T cell lineage commitment 0.988345 15607 fatty acyl CoA transporter activity 0.988314 15919 peroxisomal membrane transport 0.988314 15246 fatty acyl transporter activity 0.988314 5325 peroxisomal fatty acyl CoA transporter activity 0.988314 5324 long-chain fatty acid transporter activity 0.988314 31547 brain-derived neurotrophic factor receptor signaling pathway 0.988266 48403 brain-derived neurotrophic factor binding 0.988266 14805 smooth muscle adaptation 0.988240 3057 regulation of the force of heart contraction by chemical signal 0.988216 70369 beta-catenin-TCF7L2 complex 0.988193 10908 regulation of heparan sulfate proteoglycan biosynthetic process 0.988193 10909 positive regulation of heparan sulfate proteoglycan biosynthetic process 0.988193 51176 positive regulation of sulfur metabolic process 0.988193 10875 positive regulation of cholesterol efflux 0.988175 35087 siRNA loading onto RISC involved in RNA interference 0.988169 51736 ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity 0.988169 51732 polyribonucleotide kinase activity 0.988169 60159 regulation of dopamine receptor signaling pathway 0.988168 10756 positive regulation of plasminogen activation 0.988121 51787 misfolded protein binding 0.988121 45988 negative regulation of striated muscle contraction 0.988121 70408 carbamoyl phosphate metabolic process 0.988073 70409 carbamoyl phosphate biosynthetic process 0.988073 4087 carbamoyl-phosphate synthase (ammonia) activity 0.988073 33085 negative regulation of T cell differentiation in the thymus 0.988072 33160 positive regulation of protein import into nucleus, translocation 0.988054 60390 regulation of SMAD protein nuclear translocation 0.988054 60391 positive regulation of SMAD protein nuclear translocation 0.988054 33087 negative regulation of immature T cell proliferation 0.988048 33088 negative regulation of immature T cell proliferation in the thymus 0.988048 33083 regulation of immature T cell proliferation 0.988048 33084 regulation of immature T cell proliferation in the thymus 0.988048 6554 lysine catabolic process 0.988025 6553 lysine metabolic process 0.988025 47130 saccharopine dehydrogenase (NADP+, L-lysine-forming) activity 0.988025 46440 L-lysine metabolic process 0.988025 19477 L-lysine catabolic process 0.988025 7132 meiotic metaphase I 0.988024 51295 establishment of meiotic spindle localization 0.988024 1845 phagolysosome formation 0.987976 51125 regulation of actin nucleation 0.987976 51126 negative regulation of actin nucleation 0.987976 15684 ferrous iron transport 0.987952 15093 ferrous iron transmembrane transporter activity 0.987952 15087 cobalt ion transmembrane transporter activity 0.987952 4056 argininosuccinate lyase activity 0.987928 53 argininosuccinate metabolic process 0.987928 19676 ammonia assimilation cycle 0.987928 42450 arginine biosynthetic process via ornithine 0.987928 60544 regulation of necroptosis 0.987927 60545 positive regulation of necroptosis 0.987927 60553 induction of necroptosis 0.987927 60555 induction of necroptosis by extracellular signals 0.987927 3990 acetylcholinesterase activity 0.987880 32223 negative regulation of synaptic transmission, cholinergic 0.987880 1661 conditioned taste aversion 0.987878 33677 DNA/RNA helicase activity 0.987831 33678 5'-3' DNA/RNA helicase activity 0.987831 33682 ATP-dependent 5'-3' DNA/RNA helicase activity 0.987831 33680 ATP-dependent DNA/RNA helicase activity 0.987831 60420 regulation of heart growth 0.987815 4158 dihydroorotate oxidase activity 0.987807 4152 dihydroorotate dehydrogenase activity 0.987807 10880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 0.987798 2317 plasma cell differentiation 0.987783 48621 post-embryonic gut morphogenesis 0.987783 16333 morphogenesis of follicular epithelium 0.987783 33152 immunoglobulin V(D)J recombination 0.987758 32807 DNA ligase IV complex 0.987758 10543 regulation of platelet activation 0.987752 2576 platelet degranulation 0.987735 10807 regulation of synaptic vesicle priming 0.987735 32229 negative regulation of synaptic transmission, GABAergic 0.987735 2355 detection of tumor cell 0.987687 60055 angiogenesis involved in wound healing 0.987685 45824 negative regulation of innate immune response 0.987673 51136 regulation of NK T cell differentiation 0.987662 51138 positive regulation of NK T cell differentiation 0.987662 45189 connective tissue growth factor biosynthetic process 0.987638 5136 interleukin-4 receptor binding 0.987638 3085 negative regulation of systemic arterial blood pressure 0.987635 32494 response to peptidoglycan 0.987626 55015 ventricular cardiac muscle cell development 0.987624 32389 MutLalpha complex 0.987590 5134 interleukin-2 receptor binding 0.987589 9164 nucleoside catabolic process 0.987579 34443 negative regulation of lipoprotein oxidation 0.987573 34442 regulation of lipoprotein oxidation 0.987573 8794 arsenate reductase (glutaredoxin) activity 0.987493 30613 oxidoreductase activity, acting on phosphorus or arsenic in donors 0.987493 30614 oxidoreductase activity, acting on phosphorus or arsenic in donors, with disulfide as acceptor 0.987493 42262 DNA protection 0.987493 10902 positive regulation of very-low-density lipoprotein particle remodeling 0.987493 4772 sterol O-acyltransferase activity 0.987469 10453 regulation of cell fate commitment 0.987469 10454 negative regulation of cell fate commitment 0.987469 42824 MHC class I peptide loading complex 0.987469 34736 cholesterol O-acyltransferase activity 0.987469 34737 ergosterol O-acyltransferase activity 0.987469 34738 lanosterol O-acyltransferase activity 0.987469 17066 sterol O-acyltransferase activity 0.987469 33993 response to lipid 0.987465 4555 alpha,alpha-trehalase activity 0.987445 15927 trehalase activity 0.987445 5991 trehalose metabolic process 0.987445 5993 trehalose catabolic process 0.987445 46352 disaccharide catabolic process 0.987445 32656 regulation of interleukin-13 production 0.987444 32305 positive regulation of icosanoid secretion 0.987420 32303 regulation of icosanoid secretion 0.987420 32308 positive regulation of prostaglandin secretion 0.987420 32306 regulation of prostaglandin secretion 0.987420 32370 positive regulation of lipid transport 0.987419 45257 succinate dehydrogenase complex (ubiquinone) 0.987397 45281 succinate dehydrogenase complex 0.987397 45283 fumarate reductase complex 0.987397 5749 mitochondrial respiratory chain complex II 0.987397 31514 motile secondary cilium 0.987395 60296 regulation of cilium beat frequency involved in ciliary motility 0.987395 60295 regulation of cilium movement involved in cell motility 0.987395 3352 regulation of cilium movement 0.987395 7435 salivary gland morphogenesis 0.987386 70022 transforming growth factor beta receptor complex 0.987379 2693 positive regulation of cellular extravasation 0.987348 2691 regulation of cellular extravasation 0.987348 2457 T cell antigen processing and presentation 0.987348 51926 negative regulation of calcium ion transport 0.987338 32376 positive regulation of cholesterol transport 0.987324 32373 positive regulation of sterol transport 0.987324 35238 vitamin A biosynthetic process 0.987300 47035 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity 0.987300 42904 9-cis-retinoic acid biosynthetic process 0.987300 42905 9-cis-retinoic acid metabolic process 0.987300 44240 multicellular organismal lipid catabolic process 0.987267 8522 nucleoside:sodium symporter activity 0.987252 15864 pyrimidine nucleoside transport 0.987252 15390 purine-specific nucleoside:sodium symporter activity 0.987252 15389 pyrimidine- and adenine-specific:sodium symporter activity 0.987252 10940 positive regulation of necrotic cell death 0.987251 10939 regulation of necrotic cell death 0.987251 45852 pH elevation 0.987204 51454 intracellular pH elevation 0.987204 45425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process 0.987202 43525 positive regulation of neuron apoptosis 0.987189 32515 negative regulation of phosphoprotein phosphatase activity 0.987122 14048 regulation of glutamate secretion 0.987107 14049 positive regulation of glutamate secretion 0.987107 51955 regulation of amino acid transport 0.987093 15865 purine nucleotide transport 0.987082 15867 ATP transport 0.987082 15868 purine ribonucleotide transport 0.987082 51503 adenine nucleotide transport 0.987082 51702 interaction with symbiont 0.987079 2820 negative regulation of adaptive immune response 0.987069 2823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 0.987069 43084 penile erection 0.987059 42713 sperm ejaculation 0.987059 30977 taurine binding 0.987010 50886 endocrine process 0.987009 1990 regulation of systemic arterial blood pressure by hormone 0.987009 3044 regulation of systemic arterial blood pressure mediated by a chemical signal 0.987009 3073 regulation of systemic arterial blood pressure 0.987009 6447 regulation of translational initiation by iron 0.986986 51088 PMA-inducible membrane protein ectodomain proteolysis 0.986945 43125 ErbB-3 class receptor binding 0.986929 48671 negative regulation of collateral sprouting 0.986914 48670 regulation of collateral sprouting 0.986914 21933 radial glia guided migration of granule cell 0.986914 6207 'de novo' pyrimidine base biosynthetic process 0.986900 19856 pyrimidine base biosynthetic process 0.986900 60399 positive regulation of growth hormone receptor signaling pathway 0.986889 60398 regulation of growth hormone receptor signaling pathway 0.986889 6407 rRNA export from nucleus 0.986866 51029 rRNA transport 0.986866 51894 positive regulation of focal adhesion formation 0.986866 48269 methionine adenosyltransferase complex 0.986817 48270 methionine adenosyltransferase regulator activity 0.986817 8831 dTDP-4-dehydrorhamnose reductase activity 0.986817 45226 extracellular polysaccharide biosynthetic process 0.986817 46379 extracellular polysaccharide metabolic process 0.986817 43568 positive regulation of insulin-like growth factor receptor signaling pathway 0.986786 33629 negative regulation of cell adhesion mediated by integrin 0.986769 43951 negative regulation of cAMP-mediated signaling 0.986769 43949 regulation of cAMP-mediated signaling 0.986769 45509 interleukin-27 receptor activity 0.986768 48184 follistatin binding 0.986744 4507 steroid 11-beta-monooxygenase activity 0.986744 8212 mineralocorticoid metabolic process 0.986744 45636 positive regulation of melanocyte differentiation 0.986744 6705 mineralocorticoid biosynthetic process 0.986744 50942 positive regulation of pigment cell differentiation 0.986744 32342 aldosterone biosynthetic process 0.986744 32341 aldosterone metabolic process 0.986744 34651 cortisol biosynthetic process 0.986744 34650 cortisol metabolic process 0.986744 2084 protein depalmitoylation 0.986721 50803 regulation of synapse structure and activity 0.986721 32516 positive regulation of phosphoprotein phosphatase activity 0.986696 34371 chylomicron remodeling 0.986687 42610 CD8 receptor binding 0.986672 60381 positive regulation of single-stranded telomeric DNA binding 0.986624 60380 regulation of single-stranded telomeric DNA binding 0.986624 32730 positive regulation of interleukin-1 alpha production 0.986624 32650 regulation of interleukin-1 alpha production 0.986624 32637 interleukin-8 production 0.986576 60397 JAK-STAT cascade involved in growth hormone signaling pathway 0.986550 4517 nitric-oxide synthase activity 0.986542 34186 apolipoprotein A-I binding 0.986542 34618 arginine binding 0.986542 34617 tetrahydrobiopterin binding 0.986542 14826 vein smooth muscle contraction 0.986526 15789 UDP-N-acetylgalactosamine transport 0.986479 5461 UDP-glucuronic acid transmembrane transporter activity 0.986479 5463 UDP-N-acetylgalactosamine transmembrane transporter activity 0.986479 43006 activation of phospholipase A2 activity by calcium-mediated signaling 0.986479 9448 gamma-aminobutyric acid metabolic process 0.986462 10039 response to iron ion 0.986441 4080 biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity 0.986431 4079 biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity 0.986431 4078 biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity 0.986431 4077 biotin-[acetyl-CoA-carboxylase] ligase activity 0.986431 18271 biotin-protein ligase activity 0.986431 106 biotin-protein ligase activity 0.986431 51983 regulation of chromosome segregation 0.986398 90153 regulation of sphingolipid biosynthetic process 0.986383 90155 negative regulation of sphingolipid biosynthetic process 0.986383 46318 negative regulation of glucosylceramide biosynthetic process 0.986383 46317 regulation of glucosylceramide biosynthetic process 0.986383 45073 regulation of chemokine biosynthetic process 0.986372 4698 calcium-dependent protein kinase C activity 0.986334 10857 calcium-dependent protein kinase activity 0.986334 9931 calcium-dependent protein serine/threonine kinase activity 0.986334 32735 positive regulation of interleukin-12 production 0.986332 60788 ectodermal placode formation 0.986317 35229 positive regulation of glutamate-cysteine ligase activity 0.986286 35227 regulation of glutamate-cysteine ligase activity 0.986286 35226 glutamate-cysteine ligase catalytic subunit binding 0.986286 48521 negative regulation of behavior 0.986269 22028 tangential migration from the subventricular zone to the olfactory bulb 0.986238 21831 embryonic olfactory bulb interneuron precursor migration 0.986238 21759 globus pallidus development 0.986238 51927 negative regulation of calcium ion transport via voltage-gated calcium channel activity 0.986237 51006 positive regulation of lipoprotein lipase activity 0.986210 18192 enzyme active site formation via L-cysteine persulfide 0.986141 18307 enzyme active site formation 0.986141 42292 URM1 activating enzyme activity 0.986141 46049 UMP metabolic process 0.986140 9173 pyrimidine ribonucleoside monophosphate metabolic process 0.986140 9174 pyrimidine ribonucleoside monophosphate biosynthetic process 0.986140 60317 cardiac epithelial to mesenchymal transition 0.986140 6222 UMP biosynthetic process 0.986140 10560 positive regulation of glycoprotein biosynthetic process 0.986103 55021 regulation of cardiac muscle tissue growth 0.986103 55024 regulation of cardiac muscle tissue development 0.986103 60043 regulation of cardiac muscle cell proliferation 0.986103 50675 regulation of urothelial cell proliferation 0.986093 50677 positive regulation of urothelial cell proliferation 0.986093 32430 positive regulation of phospholipase A2 activity 0.986090 32429 regulation of phospholipase A2 activity 0.986090 31000 response to caffeine 0.986076 14074 response to purine 0.986076 4315 3-oxoacyl-[acyl-carrier-protein] synthase activity 0.986068 6746 FADH2 metabolic process 0.986068 4940 beta1-adrenergic receptor activity 0.986045 16276 histone-arginine N-methyltransferase activity 0.986020 44020 histone methyltransferase activity (H4-R3 specific) 0.986020 10887 negative regulation of cholesterol storage 0.986017 1835 blastocyst hatching 0.985996 35188 hatching 0.985996 34285 response to disaccharide stimulus 0.985948 9744 response to sucrose stimulus 0.985948 16 lactase activity 0.985948 10045 response to nickel ion 0.985948 17042 glycosylceramidase activity 0.985948 33617 mitochondrial respiratory chain complex IV assembly 0.985900 34551 mitochondrial respiratory chain complex III assembly 0.985900 17062 respiratory chain complex III assembly 0.985900 5350 pyrimidine transmembrane transporter activity 0.985875 70522 ERCC4-ERCC1 complex 0.985852 48476 Holliday junction resolvase complex 0.985852 55009 atrial cardiac muscle tissue morphogenesis 0.985802 34383 low-density lipoprotein particle clearance 0.985777 19530 taurine metabolic process 0.985765 10874 regulation of cholesterol efflux 0.985765 48194 Golgi vesicle budding 0.985755 6900 membrane budding 0.985755 6902 membrane budding 0.985755 133 polarisome 0.985755 60166 olfactory pit development 0.985754 34370 triglyceride-rich lipoprotein particle remodeling 0.985744 32890 regulation of organic acid transport 0.985744 32753 positive regulation of interleukin-4 production 0.985730 46292 formaldehyde metabolic process 0.985706 10955 negative regulation of protein maturation by peptide bond cleavage 0.985689 33143 regulation of steroid hormone receptor signaling pathway 0.985656 45083 negative regulation of interleukin-12 biosynthetic process 0.985610 48505 regulation of timing of cell differentiation 0.985596 40034 regulation of development, heterochronic 0.985596 51061 ADP reductase activity 0.985562 19303 D-ribose catabolic process 0.985562 19323 pentose catabolic process 0.985562 15956 bis(5'-nucleosidyl) oligophosphate metabolic process 0.985514 15958 bis(5'-nucleosidyl) oligophosphate catabolic process 0.985514 15959 diadenosine polyphosphate metabolic process 0.985514 15961 diadenosine polyphosphate catabolic process 0.985514 33137 negative regulation of peptidyl-serine phosphorylation 0.985512 46889 positive regulation of lipid biosynthetic process 0.985497 43090 amino acid import 0.985494 43092 L-amino acid import 0.985494 51938 L-glutamate import 0.985494 45348 positive regulation of MHC class II biosynthetic process 0.985491 45833 negative regulation of lipid metabolic process 0.985472 6907 pinocytosis 0.985465 30294 receptor signaling protein tyrosine kinase inhibitor activity 0.985465 2921 negative regulation of humoral immune response 0.985448 9313 oligosaccharide catabolic process 0.985448 3065 positive regulation of heart rate by epinephrine 0.985417 3062 regulation of heart rate by chemical signal 0.985417 43902 positive regulation of multi-organism process 0.985416 51712 positive regulation of killing of cells of another organism 0.985416 45931 positive regulation of mitotic cell cycle 0.985412 44253 positive regulation of multicellular organismal metabolic process 0.985384 43586 tongue development 0.985383 32241 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport 0.985369 46833 positive regulation of RNA export from nucleus 0.985369 7208 activation of phospholipase C activity by serotonin receptor signaling pathway 0.985368 46813 virion attachment, binding of host cell surface receptor 0.985351 31645 negative regulation of neurological system process 0.985345 60588 negative regulation of lipoprotein lipid oxidation 0.985320 60587 regulation of lipoprotein lipid oxidation 0.985320 34365 discoidal high-density lipoprotein particle 0.985320 3084 positive regulation of systemic arterial blood pressure 0.985303 46826 negative regulation of protein export from nucleus 0.985296 34656 nucleobase, nucleoside and nucleotide catabolic process 0.985295 34655 nucleobase, nucleoside, nucleotide and nucleic acid catabolic process 0.985295 52312 modulation of transcription in other organism during symbiotic interaction 0.985272 52472 modulation by host of symbiont transcription 0.985272 43921 modulation by host of viral transcription 0.985272 43923 positive regulation by host of viral transcription 0.985272 51709 regulation of killing of cells of another organism 0.985270 6678 glucosylceramide metabolic process 0.985238 55100 adiponectin binding 0.985224 55096 low-density lipoprotein mediated signaling 0.985224 55095 lipoprotein mediated signaling 0.985224 42762 regulation of sulfur metabolic process 0.985222 8049 male courtship behavior 0.985176 60179 male mating behavior 0.985176 48483 autonomic nervous system development 0.985127 21930 granule cell precursor proliferation 0.985127 21924 cell proliferation in the external granule layer 0.985127 21534 cell proliferation in hindbrain 0.985127 46113 nucleobase catabolic process 0.985127 6208 pyrimidine base catabolic process 0.985127 6212 uracil catabolic process 0.985127 6210 thymine catabolic process 0.985127 19860 uracil metabolic process 0.985127 31936 negative regulation of chromatin silencing 0.985102 31452 negative regulation of heterochromatin formation 0.985102 31445 regulation of heterochromatin formation 0.985102 10847 regulation of chromatin assembly 0.985102 45798 negative regulation of chromatin assembly or disassembly 0.985102 6345 loss of chromatin silencing 0.985102 60969 negative regulation of gene silencing 0.985102 32145 succinate-semialdehyde dehydrogenase binding 0.985079 32144 4-aminobutyrate transaminase complex 0.985079 3867 4-aminobutyrate transaminase activity 0.985079 47298 (S)-3-amino-2-methylpropionate transaminase activity 0.985079 46838 phosphorylated carbohydrate dephosphorylation 0.985054 45579 positive regulation of B cell differentiation 0.985047 10465 nerve growth factor receptor activity 0.985031 30379 neurotensin receptor activity, non-G-protein coupled 0.985031 60370 susceptibility to T cell mediated cytotoxicity 0.985006 33735 aspartate dehydrogenase activity 0.984982 6742 NADP catabolic process 0.984982 42365 water-soluble vitamin catabolic process 0.984982 19364 pyridine nucleotide catabolic process 0.984982 70165 positive regulation of adiponectin secretion 0.984934 70553 nicotinic acid receptor activity 0.984934 33029 regulation of neutrophil apoptosis 0.984934 33031 positive regulation of neutrophil apoptosis 0.984934 6747 FAD biosynthetic process 0.984886 3919 FMN adenylyltransferase activity 0.984886 46443 FAD metabolic process 0.984886 65005 protein-lipid complex assembly 0.984862 34377 plasma lipoprotein particle assembly 0.984862 8057 eye pigment granule organization 0.984838 51974 negative regulation of telomerase activity 0.984835 9128 purine nucleoside monophosphate catabolic process 0.984789 9158 ribonucleoside monophosphate catabolic process 0.984789 9169 purine ribonucleoside monophosphate catabolic process 0.984789 6196 AMP catabolic process 0.984789 16033 iron ion transmembrane transporter activity 0.984787 5382 iron ion transmembrane transporter activity 0.984787 70166 enamel mineralization 0.984741 70172 positive regulation of tooth mineralization 0.984741 10370 perinucleolar chromocenter 0.984644 10836 negative regulation of protein amino acid ADP-ribosylation 0.984644 10835 regulation of protein amino acid ADP-ribosylation 0.984644 5006 epidermal growth factor receptor activity 0.984571 15734 taurine transport 0.984548 1762 beta-alanine transport 0.984548 1761 beta-alanine transmembrane transporter activity 0.984548 5369 taurine:sodium symporter activity 0.984548 5368 taurine transmembrane transporter activity 0.984548 1743 optic placode formation 0.984523 46619 optic placode formation involved in camera-type eye 0.984523 45870 positive regulation of retroviral genome replication 0.984499 9330 DNA topoisomerase complex (ATP-hydrolyzing) 0.984499 19035 viral integration complex 0.984499 32729 positive regulation of interferon-gamma production 0.984495 45187 regulation of circadian sleep/wake cycle, sleep 0.984487 42749 regulation of circadian sleep/wake cycle 0.984487 22410 circadian sleep/wake cycle process 0.984487 15855 pyrimidine transport 0.984451 15288 porin activity 0.984451 18009 N-terminal peptidyl-L-cysteine N-palmitoylation 0.984403 18349 protein amino acid palmitoylation 0.984403 18318 protein amino acid palmitoylation 0.984403 6500 N-terminal protein palmitoylation 0.984403 2523 leukocyte migration during inflammatory response 0.984402 340 RNA 7-methylguanosine cap binding 0.984378 60236 regulation of mitotic spindle organization 0.984355 43146 spindle stabilization 0.984355 43148 mitotic spindle stabilization 0.984355 90224 regulation of spindle organization 0.984355 21772 olfactory bulb development 0.984330 50823 peptide antigen stabilization 0.984306 50822 peptide stabilization 0.984306 2262 myeloid cell homeostasis 0.984306 33780 taurochenodeoxycholate 6alpha-hydroxylase activity 0.984258 47638 albendazole monooxygenase activity 0.984258 50591 quinine 3-monooxygenase activity 0.984258 50649 testosterone 6-beta-hydroxylase activity 0.984258 48340 paraxial mesoderm morphogenesis 0.984257 50667 homocysteine metabolic process 0.984257 19344 cysteine biosynthetic process 0.984257 35307 positive regulation of protein amino acid dephosphorylation 0.984240 35306 positive regulation of dephosphorylation 0.984240 8024 positive transcription elongation factor complex b 0.984210 15846 polyamine transport 0.984210 296 spermine transport 0.984210 48854 brain morphogenesis 0.984198 30236 negative regulation of inflammatory response 0.984183 2752 cell surface pattern recognition receptor signaling pathway 0.984161 42892 chloramphenicol transport 0.984161 2634 regulation of germinal center formation 0.984110 6681 galactosylceramide metabolic process 0.984087 19374 galactolipid metabolic process 0.984087 44246 regulation of multicellular organismal metabolic process 0.984073 6116 NADH oxidation 0.984065 6734 NADH metabolic process 0.984065 1588 dopamine receptor activity, coupled via Gs 0.984064 45019 negative regulation of nitric oxide biosynthetic process 0.984016 35066 positive regulation of histone acetylation 0.984016 4760 serine-pyruvate transaminase activity 0.983968 46724 oxalic acid secretion 0.983968 19265 glycine biosynthetic process, by transamination of glyoxylate 0.983968 2023 reduction of food intake in response to dietary excess 0.983920 42986 positive regulation of amyloid precursor protein biosynthetic process 0.983919 10735 positive regulation of transcription via serum response element binding 0.983871 10736 serum response element binding 0.983871 10572 positive regulation of platelet activation 0.983854 60369 positive regulation of Fc receptor mediated stimulatory signaling pathway 0.983823 60368 regulation of Fc receptor mediated stimulatory signaling pathway 0.983823 1783 B cell apoptosis 0.983823 33861 negative regulation of NAD(P)H oxidase activity 0.983799 3071 renal system process involved in regulation of systemic arterial blood pressure 0.983790 32431 activation of phospholipase A2 activity 0.983785 32459 regulation of protein oligomerization 0.983775 32463 negative regulation of protein homooligomerization 0.983775 32460 negative regulation of protein oligomerization 0.983775 32462 regulation of protein homooligomerization 0.983775 45581 negative regulation of T cell differentiation 0.983755 15740 C4-dicarboxylate transport 0.983727 15744 succinate transport 0.983727 15141 succinate transmembrane transporter activity 0.983727 46100 hypoxanthine metabolic process 0.983693 45743 positive regulation of fibroblast growth factor receptor signaling pathway 0.983679 46121 deoxyribonucleoside catabolic process 0.983661 2238 response to molecule of fungal origin 0.983654 10820 positive regulation of T cell chemotaxis 0.983654 10819 regulation of T cell chemotaxis 0.983654 42094 interleukin-2 biosynthetic process 0.983654 10511 regulation of phosphatidylinositol biosynthetic process 0.983630 10512 negative regulation of phosphatidylinositol biosynthetic process 0.983630 31089 platelet dense granule lumen 0.983630 71072 negative regulation of phospholipid biosynthetic process 0.983630 71071 regulation of phospholipid biosynthetic process 0.983630 30290 sphingolipid activator protein activity 0.983582 32428 beta-N-acetylgalactosaminidase activity 0.983582 48006 antigen processing and presentation, endogenous lipid antigen via MHC class Ib 0.983534 30884 exogenous lipid antigen binding 0.983534 30882 lipid antigen binding 0.983534 90030 regulation of steroid hormone biosynthetic process 0.983533 30347 syntaxin-2 binding 0.983509 45415 negative regulation of interleukin-8 biosynthetic process 0.983485 32211 negative regulation of telomere maintenance via telomerase 0.983459 60356 leucine import 0.983437 15827 tryptophan transport 0.983437 15820 leucine transport 0.983437 15803 branched-chain aliphatic amino acid transport 0.983437 2036 regulation of L-glutamate transport 0.983419 2037 negative regulation of L-glutamate transport 0.983419 44070 regulation of anion transport 0.983419 51953 negative regulation of amine transport 0.983419 51956 negative regulation of amino acid transport 0.983419 42048 olfactory behavior 0.983389 14896 muscle hypertrophy 0.983387 45981 positive regulation of nucleotide metabolic process 0.983377 30804 positive regulation of cyclic nucleotide biosynthetic process 0.983377 30801 positive regulation of cyclic nucleotide metabolic process 0.983377 30810 positive regulation of nucleotide biosynthetic process 0.983377 32891 negative regulation of organic acid transport 0.983363 70551 endoribonuclease activity, cleaving siRNA-paired mRNA 0.983341 48863 stem cell differentiation 0.983340 30342 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity 0.983292 42369 vitamin D catabolic process 0.983292 70561 vitamin D receptor signaling pathway 0.983291 43296 apical junction complex 0.983291 71295 cellular response to vitamin 0.983291 71305 cellular response to vitamin D 0.983291 46638 positive regulation of alpha-beta T cell differentiation 0.983259 8434 vitamin D3 receptor activity 0.983244 2090 regulation of receptor internalization 0.983242 2092 positive regulation of receptor internalization 0.983242 19805 quinolinate biosynthetic process 0.983210 10232 vascular transport 0.983196 10746 regulation of plasma membrane long-chain fatty acid transport 0.983181 10748 negative regulation of plasma membrane long-chain fatty acid transport 0.983181 70602 regulation of centromeric sister chromatid cohesion 0.983147 43035 chromatin insulator sequence binding 0.983147 40030 regulation of molecular function, epigenetic 0.983147 55014 atrial cardiac muscle cell development 0.983122 8063 Toll signaling pathway 0.983099 9450 gamma-aminobutyric acid catabolic process 0.983098 32801 receptor catabolic process 0.983073 1779 natural killer cell differentiation 0.983065 70679 inositol 1,4,5 trisphosphate binding 0.983051 822 inositol hexakisphosphate binding 0.983051 50820 positive regulation of coagulation 0.983047 30194 positive regulation of blood coagulation 0.983047 34372 very-low-density lipoprotein particle remodeling 0.983015 50577 GDP-L-fucose synthase activity 0.983003 42356 GDP-4-dehydro-D-rhamnose reductase activity 0.983003 10467 gene expression 0.983002 33206 cytokinesis after meiosis 0.982954 16344 meiotic chromosome movement towards spindle pole 0.982954 40038 polar body extrusion after meiotic divisions 0.982954 46434 organophosphate catabolic process 0.982953 2904 positive regulation of B cell apoptosis 0.982953 10455 positive regulation of cell fate commitment 0.982906 6063 uronic acid metabolic process 0.982903 19699 glucuronate metabolic process 0.982903 19585 glucuronate metabolic process 0.982903 2220 innate immune response activating cell surface receptor signaling pathway 0.982881 45213 neurotransmitter receptor metabolic process 0.982858 46637 regulation of alpha-beta T cell differentiation 0.982833 9120 deoxyribonucleoside metabolic process 0.982831 6042 glucosamine biosynthetic process 0.982809 6045 N-acetylglucosamine biosynthetic process 0.982809 6048 UDP-N-acetylglucosamine biosynthetic process 0.982809 3977 UDP-N-acetylglucosamine diphosphorylase activity 0.982809 32808 lacrimal gland development 0.982809 45624 positive regulation of T-helper cell differentiation 0.982795 19067 viral assembly, maturation, egress, and release 0.982784 43618 regulation of transcription from RNA polymerase II promoter in response to stress 0.982767 43620 regulation of transcription in response to stress 0.982767 22009 central nervous system vasculogenesis 0.982761 60024 rhythmic synaptic transmission 0.982760 43179 rhythmic excitation 0.982760 14820 tonic smooth muscle contraction 0.982759 14824 artery smooth muscle contraction 0.982759 33364 mast cell secretory granule organization 0.982736 4588 orotate phosphoribosyltransferase activity 0.982713 4590 orotidine-5'-phosphate decarboxylase activity 0.982713 32059 bleb 0.982711 16046 detection of fungus 0.982665 60161 positive regulation of dopamine receptor signaling pathway 0.982640 51970 negative regulation of transmission of nerve impulse 0.982622 32760 positive regulation of tumor necrosis factor production 0.982618 32375 negative regulation of cholesterol transport 0.982618 32372 negative regulation of sterol transport 0.982618 60665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling 0.982616 60638 mesenchymal-epithelial cell signaling 0.982616 60693 regulation of branching involved in salivary gland morphogenesis 0.982616 60688 regulation of morphogenesis of a branching structure 0.982616 31436 BRCA1-BARD1 complex 0.982615 32225 regulation of synaptic transmission, dopaminergic 0.982597 45011 actin filament bundle formation 0.982568 43149 stress fiber formation 0.982568 30881 beta-2-microglobulin binding 0.982567 6184 GTP catabolic process 0.982543 21575 hindbrain morphogenesis 0.982543 35 acyl binding 0.982520 51342 regulation of cyclic-nucleotide phosphodiesterase activity 0.982520 51344 negative regulation of cyclic-nucleotide phosphodiesterase activity 0.982520 46016 positive regulation of transcription by glucose 0.982495 21798 forebrain dorsal/ventral pattern formation 0.982495 45991 positive regulation of transcription by carbon catabolites 0.982495 429 regulation of transcription from RNA polymerase II promoter by carbon catabolites 0.982495 430 regulation of transcription from RNA polymerase II promoter by glucose 0.982495 436 positive regulation of transcription from RNA polymerase II promoter by carbon catabolites 0.982495 432 positive regulation of transcription from RNA polymerase II promoter by glucose 0.982495 10420 polyprenyldihydroxybenzoate methyltransferase activity 0.982471 4395 hexaprenyldihydroxybenzoate methyltransferase activity 0.982471 8425 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity 0.982471 30580 quinone cofactor methyltransferase activity 0.982471 42055 neuron fate commitment 0.982469 30468 establishment of cell polarity 0.982441 283 establishment of cell polarity 0.982441 14068 positive regulation of phosphoinositide 3-kinase cascade 0.982440 4336 galactosylceramidase activity 0.982423 6683 galactosylceramide catabolic process 0.982423 19376 galactolipid catabolic process 0.982423 30423 targeting of mRNA for destruction involved in RNA interference 0.982421 31952 regulation of protein amino acid autophosphorylation 0.982420 21882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment 0.982375 21893 cerebral cortex GABAergic interneuron fate commitment 0.982375 2832 negative regulation of response to biotic stimulus 0.982374 43901 negative regulation of multi-organism process 0.982374 50689 negative regulation of defense response to virus by host 0.982374 50687 negative regulation of defense response to virus 0.982374 2828 regulation of T-helper 2 type immune response 0.982363 7256 activation of JNKK activity 0.982327 7255 activation of MAPKK activity 0.982327 34433 steroid esterification 0.982293 34435 cholesterol esterification 0.982293 34434 sterol esterification 0.982293 8204 ergosterol metabolic process 0.982278 16128 phytosteroid metabolic process 0.982278 16129 phytosteroid biosynthetic process 0.982278 6696 ergosterol biosynthetic process 0.982278 43032 positive regulation of macrophage activation 0.982264 33058 directional locomotion 0.982230 46477 glycosylceramide catabolic process 0.982212 4357 glutamate-cysteine ligase activity 0.982205 17109 glutamate-cysteine ligase complex 0.982205 60045 positive regulation of cardiac muscle cell proliferation 0.982196 60008 Sertoli cell differentiation 0.982182 32448 DNA hairpin binding 0.982182 2889 regulation of immunoglobulin mediated immune response 0.982162 2712 regulation of B cell mediated immunity 0.982162 21631 optic nerve morphogenesis 0.982148 32495 response to muramyl dipeptide 0.982148 8611 ether lipid biosynthetic process 0.982133 46485 ether lipid metabolic process 0.982133 5051 peroxisome targeting sequence binding 0.982133 5053 peroxisome matrix targeting signal-2 binding 0.982133 6005 L-fucose biosynthetic process 0.982133 46368 GDP-L-fucose metabolic process 0.982133 42351 'de novo' GDP-L-fucose biosynthetic process 0.982133 42350 GDP-L-fucose biosynthetic process 0.982133 42353 fucose biosynthetic process 0.982133 60038 cardiac muscle cell proliferation 0.982120 14855 striated muscle cell proliferation 0.982120 51055 negative regulation of lipid biosynthetic process 0.982112 48332 mesoderm morphogenesis 0.982107 45267 proton-transporting ATP synthase, catalytic core 0.982085 6933 negative regulation of cell adhesion involved in substrate-bound cell migration 0.982085 5754 mitochondrial proton-transporting ATP synthase, catalytic core 0.982085 43500 muscle adaptation 0.982081 18126 protein amino acid hydroxylation 0.982067 60261 positive regulation of transcription initiation from RNA polymerase II promoter 0.982067 10984 regulation of lipoprotein particle clearance 0.982049 10714 positive regulation of collagen metabolic process 0.982049 32967 positive regulation of collagen biosynthetic process 0.982049 42775 mitochondrial ATP synthesis coupled electron transport 0.982037 10985 negative regulation of lipoprotein particle clearance 0.982024 50966 detection of mechanical stimulus involved in sensory perception of pain 0.982012 70062 extracellular vesicular exosome 0.981989 43230 extracellular organelle 0.981989 65010 extracellular membrane-bounded organelle 0.981989 31649 heat generation 0.981975 33032 regulation of myeloid cell apoptosis 0.981969 50805 negative regulation of synaptic transmission 0.981949 10986 positive regulation of lipoprotein particle clearance 0.981940 10983 positive regulation of high-density lipoprotein particle clearance 0.981940 34236 protein kinase A catalytic subunit binding 0.981906 8478 pyridoxal kinase activity 0.981892 42822 pyridoxal phosphate metabolic process 0.981892 42823 pyridoxal phosphate biosynthetic process 0.981892 6344 maintenance of chromatin silencing 0.981891 7403 glial cell fate determination 0.981858 4971 alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity 0.981844 32279 asymmetric synapse 0.981844 10226 response to lithium ion 0.981844 6677 glycosylceramide metabolic process 0.981825 34080 CenH3-containing nucleosome assembly at centromere 0.981795 6336 DNA replication-independent nucleosome assembly 0.981795 34724 DNA replication-independent nucleosome organization 0.981795 34509 centromeric core chromatin formation 0.981795 5845 mRNA cap binding complex 0.981777 34518 RNA cap binding complex 0.981777 4641 phosphoribosylformylglycinamidine cyclo-ligase activity 0.981747 4644 phosphoribosylglycinamide formyltransferase activity 0.981747 4637 phosphoribosylamine-glycine ligase activity 0.981747 42158 lipoprotein biosynthetic process 0.981744 9597 detection of virus 0.981722 9602 detection of symbiont 0.981722 42271 susceptibility to natural killer cell mediated cytotoxicity 0.981713 5943 1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex 0.981699 16660 NADPH dehydrogenase activity 0.981602 8753 NADPH dehydrogenase (quinone) activity 0.981602 8468 NADPH dehydrogenase activity 0.981602 1512 dihydronicotinamide riboside quinone reductase activity 0.981602 3959 NADPH dehydrogenase activity 0.981602 7063 regulation of sister chromatid cohesion 0.981601 46636 negative regulation of alpha-beta T cell activation 0.981575 42111 T cell proliferation 0.981560 2418 immune response to tumor cell 0.981554 2223 stimulatory C-type lectin receptor signaling pathway 0.981554 10574 regulation of vascular endothelial growth factor production 0.981541 15091 ferric iron transmembrane transporter activity 0.981529 183 chromatin silencing at rDNA 0.981505 70230 positive regulation of lymphocyte apoptosis 0.981503 10149 senescence 0.981493 32214 negative regulation of telomere maintenance via semi-conservative replication 0.981481 32213 regulation of telomere maintenance via semi-conservative replication 0.981481 33553 rDNA heterochromatin 0.981457 5731 nucleolus organizer region 0.981457 30874 nucleolar chromatin 0.981457 14065 phosphoinositide 3-kinase cascade 0.981445 30823 regulation of cGMP metabolic process 0.981421 30826 regulation of cGMP biosynthetic process 0.981421 32028 myosin head/neck binding 0.981409 70372 regulation of ERK1 and ERK2 cascade 0.981391 70374 positive regulation of ERK1 and ERK2 cascade 0.981391 50798 activated T cell proliferation 0.981384 1913 T cell mediated cytotoxicity 0.981384 14848 urinary tract smooth muscle contraction 0.981384 14832 urinary bladder smooth muscle contraction 0.981384 45776 negative regulation of blood pressure 0.981372 42159 lipoprotein catabolic process 0.981367 10712 regulation of collagen metabolic process 0.981364 4788 thiamin diphosphokinase activity 0.981361 9229 thiamin diphosphate biosynthetic process 0.981361 42724 thiamin and derivative biosynthetic process 0.981361 42357 thiamin diphosphate metabolic process 0.981361 43271 negative regulation of ion transport 0.981358 46635 positive regulation of alpha-beta T cell activation 0.981351 10717 regulation of epithelial to mesenchymal transition 0.981288 33162 melanosome membrane 0.981287 31062 positive regulation of histone methylation 0.981246 48087 positive regulation of pigmentation during development 0.981230 8446 GDP-mannose 4,6-dehydratase activity 0.981216 6532 aspartate biosynthetic process 0.981215 19551 glutamate catabolic process to 2-oxoglutarate 0.981215 19550 glutamate catabolic process to aspartate 0.981215 51954 positive regulation of amine transport 0.981197 32026 response to magnesium ion 0.981191 10430 fatty acid omega-oxidation 0.981168 35276 ethanol binding 0.981168 43225 anion transmembrane-transporting ATPase activity 0.981119 8491 arsenite secondary active transmembrane transporter activity 0.981119 8490 arsenite secondary active transmembrane transporter activity 0.981119 15446 arsenite transmembrane-transporting ATPase activity 0.981119 4777 succinate-semialdehyde dehydrogenase activity 0.981071 6083 acetate metabolic process 0.981071 8292 acetylcholine biosynthetic process 0.981023 5307 choline:sodium symporter activity 0.981023 5306 choline transmembrane transporter activity 0.981023 16277 [myelin basic protein]-arginine N-methyltransferase activity 0.980926 45716 positive regulation of low-density lipoprotein receptor biosynthetic process 0.980830 6994 positive regulation of transcription via sterol regulatory element binding involved in ER-nuclear sterol response pathway 0.980830 35104 positive regulation of transcription via sterol regulatory element binding 0.980830 46398 UDP-glucuronate metabolic process 0.980779 42483 negative regulation of odontogenesis 0.980756 70141 response to UV-A 0.980747 10916 negative regulation of very-low-density lipoprotein particle clearance 0.980694 10915 regulation of very-low-density lipoprotein particle clearance 0.980694 55064 chloride ion homeostasis 0.980636 55083 monovalent inorganic anion homeostasis 0.980636 30644 cellular chloride ion homeostasis 0.980636 30320 cellular monovalent inorganic anion homeostasis 0.980636 21860 pyramidal neuron development 0.980563 45005 maintenance of fidelity during DNA-dependent DNA replication 0.980549 1754 eye photoreceptor cell differentiation 0.980540 46530 photoreceptor cell differentiation 0.980540 7467 photoreceptor cell differentiation 0.980540 2673 regulation of acute inflammatory response 0.980517 35241 protein-arginine omega-N monomethyltransferase activity 0.980506 3108 negative regulation of the force of heart contraction by chemical signal 0.980492 2444 myeloid leukocyte mediated immunity 0.980477 2446 neutrophil mediated immunity 0.980477 14056 regulation of acetylcholine secretion 0.980466 33135 regulation of peptidyl-serine phosphorylation 0.980461 31058 positive regulation of histone modification 0.980455 45834 positive regulation of lipid metabolic process 0.980443 45609 positive regulation of auditory receptor cell differentiation 0.980443 45633 positive regulation of mechanoreceptor differentiation 0.980443 42667 auditory receptor cell fate specification 0.980443 9106 lipoate metabolic process 0.980442 9107 lipoate biosynthetic process 0.980442 9105 lipoic acid biosynthetic process 0.980442 273 lipoic acid metabolic process 0.980442 51076 Gram-positive bacterial binding 0.980425 30877 beta-catenin destruction complex 0.980404 32838 cell projection cytoplasm 0.980370 32839 dendrite cytoplasm 0.980370 60760 positive regulation of response to cytokine stimulus 0.980370 16509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity 0.980347 16508 long-chain-enoyl-CoA hydratase activity 0.980347 16507 fatty acid beta-oxidation multienzyme complex 0.980347 2821 positive regulation of adaptive immune response 0.980326 18283 iron incorporation into metallo-sulfur cluster 0.980322 18282 metal incorporation into metallo-sulfur cluster 0.980322 55091 phospholipid homeostasis 0.980304 32897 negative regulation of viral transcription 0.980298 46597 negative regulation of virion penetration into host cell 0.980298 21569 rhombomere 3 development 0.980297 35242 protein-arginine omega-N asymmetric methyltransferase activity 0.980249 35247 peptidyl-arginine omega-N-methylation 0.980249 46439 L-cysteine metabolic process 0.980249 19919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine 0.980249 46080 dUTP metabolic process 0.980202 9211 pyrimidine deoxyribonucleoside triphosphate metabolic process 0.980202 4170 dUTP diphosphatase activity 0.980202 43330 response to exogenous dsRNA 0.980189 1960 negative regulation of cytokine-mediated signaling pathway 0.980187 70836 caveola assembly 0.980177 1765 membrane raft assembly 0.980177 33138 positive regulation of peptidyl-serine phosphorylation 0.980155 48003 antigen processing and presentation of lipid antigen via MHC class Ib 0.980153 2475 antigen processing and presentation via MHC class Ib 0.980153 14066 regulation of phosphoinositide 3-kinase cascade 0.980091 46621 negative regulation of organ growth 0.980087 7418 ventral midline development 0.980056 45143 homologous chromosome segregation 0.980009 45875 negative regulation of sister chromatid cohesion 0.980009 32714 negative regulation of interleukin-5 production 0.979960 32696 negative regulation of interleukin-13 production 0.979960 15105 arsenite transmembrane transporter activity 0.979959 5503 all-trans retinal binding 0.979912 19115 benzaldehyde dehydrogenase activity 0.979912 21568 rhombomere 2 development 0.979911 31690 adrenergic receptor binding 0.979878 32768 regulation of monooxygenase activity 0.979870 16727 oxidoreductase activity, acting on CH or CH2 groups, oxygen as acceptor 0.979864 4855 xanthine oxidase activity 0.979864 10044 response to aluminum ion 0.979864 2758 innate immune response-activating signal transduction 0.979831 2219 activation of innate immune response 0.979831 2218 activation of innate immune response 0.979831 2718 regulation of cytokine production during immune response 0.979828 32786 positive regulation of RNA elongation 0.979815 32784 regulation of RNA elongation 0.979815 30816 positive regulation of cAMP metabolic process 0.979789 30819 positive regulation of cAMP biosynthetic process 0.979789 44269 glycerol ether catabolic process 0.979775 46464 acylglycerol catabolic process 0.979775 46461 neutral lipid catabolic process 0.979775 70637 pyridine nucleoside metabolic process 0.979718 70638 pyridine nucleoside catabolic process 0.979718 6738 nicotinamide riboside catabolic process 0.979718 46495 nicotinamide riboside metabolic process 0.979718 19230 proprioception 0.979718 10713 negative regulation of collagen metabolic process 0.979717 44252 negative regulation of multicellular organismal metabolic process 0.979717 42487 regulation of odontogenesis of dentine-containing tooth 0.979694 42726 riboflavin and derivative metabolic process 0.979670 42727 riboflavin and derivative biosynthetic process 0.979670 50777 negative regulation of immune response 0.979654 6862 nucleotide transport 0.979653 2819 regulation of adaptive immune response 0.979642 2675 positive regulation of acute inflammatory response 0.979628 46634 regulation of alpha-beta T cell activation 0.979625 35112 genitalia morphogenesis 0.979621 43548 phosphoinositide 3-kinase binding 0.979593 2221 pattern recognition receptor signaling pathway 0.979593 2224 toll-like receptor signaling pathway 0.979593 15819 lysine transport 0.979574 15326 cationic amino acid transmembrane transporter activity 0.979574 15189 L-lysine transmembrane transporter activity 0.979574 6114 glycerol biosynthetic process 0.979573 19401 alditol biosynthetic process 0.979573 10575 positive regulation vascular endothelial growth factor production 0.979549 9151 purine deoxyribonucleotide metabolic process 0.979493 2824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 0.979479 2544 chronic inflammatory response 0.979459 45622 regulation of T-helper cell differentiation 0.979451 30616 transforming growth factor beta receptor, common-partner cytoplasmic mediator activity 0.979429 45145 single-stranded DNA specific 5'-3' exodeoxyribonuclease activity 0.979381 51908 double-stranded DNA specific 5'-3' exodeoxyribonuclease activity 0.979381 32965 regulation of collagen biosynthetic process 0.979338 10826 negative regulation of centrosome duplication 0.979333 43023 ribosomal large subunit binding 0.979333 42312 regulation of vasodilation 0.979275 32673 regulation of interleukin-4 production 0.979258 45955 negative regulation of calcium ion-dependent exocytosis 0.979236 51153 regulation of striated muscle cell differentiation 0.979222 21936 regulation of granule cell precursor proliferation 0.979197 21940 positive regulation of granule cell precursor proliferation 0.979197 2886 regulation of myeloid leukocyte mediated immunity 0.979190 31335 regulation of sulfur amino acid metabolic process 0.979188 50666 regulation of homocysteine metabolic process 0.979188 70777 D-aspartate transport 0.979186 70779 D-aspartate import 0.979186 2862 negative regulation of inflammatory response to antigenic stimulus 0.979186 21843 substrate-independent telencephalic tangential interneuron migration 0.979185 21853 cerebral cortex GABAergic interneuron migration 0.979185 21826 substrate-independent telencephalic tangential migration 0.979185 21830 interneuron migration from the subpallium to the cortex 0.979185 30037 actin filament reorganization during cell cycle 0.979140 7012 actin cytoskeleton reorganization 0.979140 2822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 0.979138 33256 I-kappaB/NF-kappaB complex 0.979136 32417 positive regulation of sodium:hydrogen antiporter activity 0.979114 46620 regulation of organ growth 0.979107 46641 positive regulation of alpha-beta T cell proliferation 0.979100 46622 positive regulation of organ growth 0.979094 51977 lysophospholipid transport 0.979091 4135 amylo-alpha-1,6-glucosidase activity 0.979043 4134 4-alpha-glucanotransferase activity 0.979043 4133 glycogen debranching enzyme activity 0.979043 43033 isoamylase complex 0.979043 32109 positive regulation of response to nutrient levels 0.979020 32106 positive regulation of response to extracellular stimulus 0.979020 32096 negative regulation of response to food 0.979009 32099 negative regulation of appetite 0.979009 43184 vascular endothelial growth factor receptor 2 binding 0.978995 43183 vascular endothelial growth factor receptor 1 binding 0.978995 32104 regulation of response to extracellular stimulus 0.978957 32107 regulation of response to nutrient levels 0.978957 43126 regulation of 1-phosphatidylinositol 4-kinase activity 0.978946 43128 positive regulation of 1-phosphatidylinositol 4-kinase activity 0.978946 31433 telethonin binding 0.978898 46015 regulation of transcription by glucose 0.978880 45990 regulation of transcription by carbon catabolites 0.978880 48406 nerve growth factor binding 0.978875 16078 tRNA catabolic process 0.978850 1682 tRNA 5'-leader removal 0.978850 171 ribonuclease MRP activity 0.978850 51279 regulation of release of sequestered calcium ion into cytosol 0.978831 43619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress 0.978798 10718 positive regulation of epithelial to mesenchymal transition 0.978761 10770 positive regulation of cell morphogenesis involved in differentiation 0.978761 15173 aromatic amino acid transmembrane transporter activity 0.978753 5302 L-tyrosine transmembrane transporter activity 0.978753 18350 protein amino acid esterification 0.978705 44258 intestinal lipid catabolic process 0.978705 43266 regulation of potassium ion transport 0.978700 8090 retrograde axon cargo transport 0.978680 32108 negative regulation of response to nutrient levels 0.978662 32105 negative regulation of response to extracellular stimulus 0.978662 31094 platelet dense tubular network 0.978608 15433 peptide antigen-transporting ATPase activity 0.978590 15440 peptide-transporting ATPase activity 0.978590 45916 negative regulation of complement activation 0.978583 1868 regulation of complement activation, lectin pathway 0.978583 1869 negative regulation of complement activation, lectin pathway 0.978583 30449 regulation of complement activation 0.978583 31077 post-embryonic camera-type eye development 0.978560 43480 pigment accumulation in tissues 0.978560 45922 negative regulation of fatty acid metabolic process 0.978547 14002 astrocyte development 0.978521 51637 Gram-positive bacterial cell surface binding 0.978511 70613 regulation of protein processing 0.978508 10953 regulation of protein maturation by peptide bond cleavage 0.978508 43696 dedifferentiation 0.978463 43697 cell dedifferentiation 0.978463 42063 gliogenesis 0.978463 51967 negative regulation of synaptic transmission, glutamatergic 0.978461 10216 maintenance of DNA methylation 0.978429 32413 negative regulation of ion transmembrane transporter activity 0.978426 10799 regulation of peptidyl-threonine phosphorylation 0.978424 48382 mesendoderm development 0.978415 32095 regulation of response to food 0.978410 45416 positive regulation of interleukin-8 biosynthetic process 0.978381 48293 regulation of isotype switching to IgE isotypes 0.978381 117 regulation of transcription involved in G2/M-phase of mitotic cell cycle 0.978367 43300 regulation of leukocyte degranulation 0.978329 46203 spermidine catabolic process 0.978319 34038 deoxyhypusine synthase activity 0.978319 50983 spermidine catabolic process to deoxyhypusine, using deoxyhypusine synthase 0.978319 2060 purine binding 0.978303 2054 nucleobase binding 0.978303 33144 negative regulation of steroid hormone receptor signaling pathway 0.978300 8705 methionine synthase activity 0.978270 4156 dihydropteroate synthase activity 0.978270 42084 5-methyltetrahydrofolate-dependent methyltransferase activity 0.978270 34381 lipoprotein particle clearance 0.978267 51450 myoblast proliferation 0.978255 9200 deoxyribonucleoside triphosphate metabolic process 0.978236 31997 N-terminal myristoylation domain binding 0.978222 60316 positive regulation of ryanodine-sensitive calcium-release channel activity 0.978222 31953 negative regulation of protein amino acid autophosphorylation 0.978219 17004 cytochrome complex assembly 0.978204 46293 formaldehyde biosynthetic process 0.978174 46184 aldehyde biosynthetic process 0.978174 43367 CD4-positive, alpha beta T cell differentiation 0.978160 48478 replication fork protection 0.978156 6682 galactosylceramide biosynthetic process 0.978125 19375 galactolipid biosynthetic process 0.978125 2017 regulation of blood volume by renal aldosterone 0.978076 1977 renal system process involved in regulation of blood volume 0.978076 32814 regulation of natural killer cell activation 0.978063 32816 positive regulation of natural killer cell activation 0.978063 15872 dopamine transport 0.978050 15873 monoamine transport 0.978045 10507 negative regulation of autophagy 0.978004 16242 negative regulation of macroautophagy 0.978004 10042 response to manganese ion 0.978004 45683 negative regulation of epidermis development 0.977980 50994 regulation of lipid catabolic process 0.977939 70212 protein amino acid poly-ADP-ribosylation 0.977932 70213 protein amino acid auto-ADP-ribosylation 0.977932 10671 negative regulation of oxygen and reactive oxygen species metabolic process 0.977931 60396 growth hormone receptor signaling pathway 0.977893 71378 cellular response to growth hormone stimulus 0.977893 50717 positive regulation of interleukin-1 alpha secretion 0.977884 50705 regulation of interleukin-1 alpha secretion 0.977884 48871 multicellular organismal homeostasis 0.977856 60120 inner ear receptor cell fate commitment 0.977836 9912 auditory receptor cell fate commitment 0.977836 42492 gamma-delta T cell differentiation 0.977836 50482 arachidonic acid secretion 0.977828 32309 icosanoid secretion 0.977828 60416 response to growth hormone stimulus 0.977812 31946 regulation of glucocorticoid biosynthetic process 0.977787 4883 glucocorticoid receptor activity 0.977787 51374 FATZ 1 binding 0.977739 51370 ZASP binding 0.977739 9299 mRNA transcription 0.977716 60707 trophoblast giant cell differentiation 0.977691 60706 cell differentiation involved in embryonic placenta development 0.977691 46601 positive regulation of centriole replication 0.977691 2548 monocyte chemotaxis 0.977676 32097 positive regulation of response to food 0.977673 32100 positive regulation of appetite 0.977673 1562 response to protozoan 0.977663 6534 cysteine metabolic process 0.977645 60076 excitatory synapse 0.977569 14802 terminal cisterna 0.977569 46629 gamma-delta T cell activation 0.977560 16982 alpha-glucosidase activity 0.977546 4575 sucrose alpha-glucosidase activity 0.977546 4574 oligo-1,6-glucosidase activity 0.977546 4562 alpha-glucosidase activity 0.977546 10519 negative regulation of phospholipase activity 0.977521 51898 negative regulation of protein kinase B signaling cascade 0.977503 6273 lagging strand elongation 0.977498 6272 leading strand elongation 0.977498 16743 carboxyl- or carbamoyltransferase activity 0.977497 50862 positive regulation of T cell receptor signaling pathway 0.977479 42415 norepinephrine metabolic process 0.977458 46118 7-methylguanosine biosynthetic process 0.977448 46116 queuosine metabolic process 0.977448 46114 guanosine biosynthetic process 0.977448 8618 7-methylguanosine metabolic process 0.977448 8616 queuosine biosynthetic process 0.977448 8479 queuine tRNA-ribosyltransferase activity 0.977448 43476 pigment accumulation 0.977415 46703 natural killer cell lectin-like receptor binding 0.977376 31061 negative regulation of histone methylation 0.977352 30540 female genitalia development 0.977352 51570 regulation of histone H3-K9 methylation 0.977352 51571 positive regulation of histone H3-K4 methylation 0.977352 51573 negative regulation of histone H3-K9 methylation 0.977352 10506 regulation of autophagy 0.977337 34367 macromolecular complex remodeling 0.977320 34368 protein-lipid complex remodeling 0.977320 34369 plasma lipoprotein particle remodeling 0.977320 34243 regulation of RNA elongation from RNA polymerase II promoter 0.977256 32968 positive regulation of RNA elongation from RNA polymerase II promoter 0.977256 35089 establishment of apical/basal cell polarity 0.977213 31855 oxytocin receptor binding 0.977208 31895 V1B vasopressin receptor binding 0.977208 43307 eosinophil activation 0.977160 43308 eosinophil degranulation 0.977160 60560 developmental growth involved in morphogenesis 0.977134 32374 regulation of cholesterol transport 0.977117 32371 regulation of sterol transport 0.977117 10904 regulation of UDP-glucose catabolic process 0.977111 10905 negative regulation of UDP-glucose catabolic process 0.977111 9162 deoxyribonucleoside monophosphate metabolic process 0.977086 2709 regulation of T cell mediated immunity 0.977069 46403 polynucleotide 3'-phosphatase activity 0.977063 46939 nucleotide phosphorylation 0.977063 9651 response to salt stress 0.977056 70234 positive regulation of T cell apoptosis 0.977015 70245 positive regulation of thymocyte apoptosis 0.977015 48550 negative regulation of pinocytosis 0.977014 10866 regulation of triglyceride biosynthetic process 0.977014 10867 positive regulation of triglyceride biosynthetic process 0.977014 4409 homoaconitate hydratase activity 0.976967 60315 negative regulation of ryanodine-sensitive calcium-release channel activity 0.976965 42115 B cell differentiation 0.976929 30885 regulation of myeloid dendritic cell activation 0.976917 42940 D-amino acid transport 0.976903 33089 positive regulation of T cell differentiation in the thymus 0.976884 50968 detection of chemical stimulus involved in sensory perception of pain 0.976870 32421 stereocilium bundle 0.976870 3983 UTP:glucose-1-phosphate uridylyltransferase activity 0.976822 51748 UTP-monosaccharide-1-phosphate uridylyltransferase activity 0.976822 60124 positive regulation of growth hormone secretion 0.976808 6065 UDP-glucuronate biosynthetic process 0.976803 46399 glucuronate biosynthetic process 0.976803 33059 cellular pigmentation 0.976796 43482 cellular pigment accumulation 0.976796 1600 endothelin-B receptor activity 0.976773 16823 hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances 0.976772 16822 hydrolase activity, acting on acid carbon-carbon bonds 0.976772 46112 nucleobase biosynthetic process 0.976752 19433 triglyceride catabolic process 0.976744 6573 valine metabolic process 0.976740 48007 antigen processing and presentation, exogenous lipid antigen via MHC class Ib 0.976725 31894 V1A vasopressin receptor binding 0.976652 31893 vasopressin receptor binding 0.976652 15693 magnesium ion transport 0.976629 9226 nucleotide-sugar biosynthetic process 0.976562 10745 negative regulation of macrophage derived foam cell differentiation 0.976532 19858 cytosine metabolic process 0.976531 31442 positive regulation of mRNA 3'-end processing 0.976484 50685 positive regulation of mRNA processing 0.976484 46101 hypoxanthine biosynthetic process 0.976458 19859 thymine metabolic process 0.976417 16890 site-specific endodeoxyribonuclease activity, specific for altered base 0.976339 45607 regulation of auditory receptor cell differentiation 0.976320 45631 regulation of mechanoreceptor differentiation 0.976320 45575 basophil activation 0.976291 1694 histamine biosynthetic process 0.976291 1692 histamine metabolic process 0.976291 46006 regulation of activated T cell proliferation 0.976287 1659 temperature homeostasis 0.976283 9608 response to symbiont 0.976275 32369 negative regulation of lipid transport 0.976271 2072 optic cup morphogenesis involved in camera-type eye development 0.976242 21768 nucleus accumbens development 0.976242 48713 regulation of oligodendrocyte differentiation 0.976239 2467 germinal center formation 0.976215 48319 axial mesoderm morphogenesis 0.976194 32368 regulation of lipid transport 0.976155 5719 nuclear euchromatin 0.976146 5701 polytene chromosome chromocenter 0.976146 6105 succinate metabolic process 0.976146 34405 response to fluid shear stress 0.976140 30858 positive regulation of epithelial cell differentiation 0.976125 33185 dolichol-phosphate-mannose synthase complex 0.976120 45627 positive regulation of T-helper 1 cell differentiation 0.976048 2755 MyD88-dependent toll-like receptor signaling pathway 0.976011 48039 ubiquinone binding 0.976001 43783 oxidoreductase activity, oxidizing metal ions with flavin as acceptor 0.976001 4795 threonine synthase activity 0.975952 9088 threonine biosynthetic process 0.975952 6566 threonine metabolic process 0.975952 50884 neuromuscular process controlling posture 0.975914 60123 regulation of growth hormone secretion 0.975906 46904 calcium oxalate binding 0.975904 16595 glutamate binding 0.975852 42977 activation of JAK2 kinase activity 0.975806 42976 activation of Janus kinase activity 0.975806 48520 positive regulation of behavior 0.975791 32959 inositol trisphosphate biosynthetic process 0.975782 32958 inositol phosphate biosynthetic process 0.975782 33578 protein amino acid glycosylation in Golgi 0.975759 8424 glycoprotein 6-alpha-L-fucosyltransferase activity 0.975759 46921 alpha(1,6)-fucosyltransferase activity 0.975759 60134 prepulse inhibition 0.975745 31998 regulation of fatty acid beta-oxidation 0.975737 32408 MutSbeta complex binding 0.975711 32406 MutLbeta complex binding 0.975711 46980 tapasin binding 0.975686 46967 cytosol to ER transport 0.975686 1954 positive regulation of cell-matrix adhesion 0.975677 2133 polycystin complex 0.975663 18216 peptidyl-arginine methylation 0.975611 60235 lens induction in camera-type eye 0.975580 1818 negative regulation of cytokine production 0.975571 2827 positive regulation of T-helper 1 type immune response 0.975566 43372 positive regulation of CD4-positive, alpha beta T cell differentiation 0.975483 30718 germ-line stem cell maintenance 0.975470 966 RNA 5'-end processing 0.975470 32352 positive regulation of hormone metabolic process 0.975466 46886 positive regulation of hormone biosynthetic process 0.975466 18987 water homeostasis 0.975435 50891 multicellular organismal water homeostasis 0.975435 46129 purine ribonucleoside biosynthetic process 0.975435 9163 nucleoside biosynthetic process 0.975435 42451 purine nucleoside biosynthetic process 0.975435 42455 ribonucleoside biosynthetic process 0.975435 16536 cyclin-dependent protein kinase 5 activator regulator activity 0.975421 3826 alpha-ketoacid dehydrogenase activity 0.975421 31348 negative regulation of defense response 0.975404 32102 negative regulation of response to external stimulus 0.975388 43370 regulation of CD4-positive, alpha beta T cell differentiation 0.975377 46633 alpha-beta T cell proliferation 0.975372 46415 urate metabolic process 0.975371 33194 response to hydroperoxide 0.975355 43140 ATP-dependent 3'-5' DNA helicase activity 0.975355 45723 positive regulation of fatty acid biosynthetic process 0.975352 60079 regulation of excitatory postsynaptic membrane potential 0.975343 42541 hemoglobin biosynthetic process 0.975330 45199 maintenance of epithelial cell apical/basal polarity 0.975276 45066 regulatory T cell differentiation 0.975275 48548 regulation of pinocytosis 0.975237 4696 glycogen synthase kinase 3 activity 0.975227 15386 potassium:hydrogen antiporter activity 0.975180 22821 potassium ion antiporter activity 0.975180 22817 potassium ion transmembrane transporter activity 0.975180 34104 negative regulation of tissue remodeling 0.975134 15911 plasma membrane long-chain fatty acid transport 0.975132 46459 short-chain fatty acid metabolic process 0.975128 45686 negative regulation of glial cell differentiation 0.975111 14014 negative regulation of gliogenesis 0.975111 32098 regulation of appetite 0.975104 30412 formimidoyltetrahydrofolate cyclodeaminase activity 0.975083 30409 glutamate formimidoyltransferase activity 0.975083 30407 formimidoyltransferase activity 0.975083 30202 heparin metabolic process 0.975082 30210 heparin biosynthetic process 0.975082 45414 regulation of interleukin-8 biosynthetic process 0.975079 70820 tertiary granule 0.975058 4345 glucose-6-phosphate dehydrogenase activity 0.975058 50857 positive regulation of antigen receptor-mediated signaling pathway 0.975040 32206 positive regulation of telomere maintenance 0.975040 14910 regulation of smooth muscle cell migration 0.975014 31848 protection from non-homologous end joining at telomere 0.975000 43247 telomere maintenance in response to DNA damage 0.975000 32000 positive regulation of fatty acid beta-oxidation 0.974995 10592 positive regulation of lamellipodium assembly 0.974987 10591 regulation of lamellipodium assembly 0.974987 51792 medium-chain fatty acid biosynthetic process 0.974938 51790 short-chain fatty acid biosynthetic process 0.974938 51791 medium-chain fatty acid metabolic process 0.974938 2699 positive regulation of immune effector process 0.974938 32277 negative regulation of gonadotropin secretion 0.974935 32276 regulation of gonadotropin secretion 0.974935 46880 regulation of follicle-stimulating hormone secretion 0.974935 46882 negative regulation of follicle-stimulating hormone secretion 0.974935 46476 glycosylceramide biosynthetic process 0.974913 45160 myosin I complex 0.974890 60171 stereocilium membrane 0.974890 5860 unconventional myosin complex 0.974890 8297 single-stranded DNA specific exodeoxyribonuclease activity 0.974889 19855 calcium channel inhibitor activity 0.974888 43048 dolichyl monophosphate biosynthetic process 0.974842 31055 chromatin remodeling at centromere 0.974807 747 conjugation with cellular fusion 0.974794 746 conjugation 0.974794 32647 regulation of interferon-alpha production 0.974747 32479 regulation of type I interferon production 0.974747 2432 granuloma formation 0.974745 43320 natural killer cell degranulation 0.974745 34418 urate biosynthetic process 0.974744 51425 PTB domain binding 0.974744 31579 membrane raft organization 0.974738 60078 regulation of postsynaptic membrane potential 0.974730 9155 purine deoxyribonucleotide catabolic process 0.974717 32554 purine deoxyribonucleotide binding 0.974697 32558 adenyl deoxyribonucleotide binding 0.974697 32490 detection of molecule of bacterial origin 0.974682 21932 hindbrain radial glia guided cell migration 0.974672 34379 very-low-density lipoprotein particle assembly 0.974659 15681 iron ion transport 0.974657 21658 rhombomere 3 morphogenesis 0.974649 21593 rhombomere morphogenesis 0.974649 70326 very-low-density lipoprotein receptor binding 0.974630 43559 insulin binding 0.974614 4557 alpha-galactosidase activity 0.974600 4422 hypoxanthine phosphoribosyltransferase activity 0.974550 43101 purine salvage 0.974538 15808 L-alanine transport 0.974536 15180 L-alanine transmembrane transporter activity 0.974536 22858 alanine transmembrane transporter activity 0.974536 32331 negative regulation of chondrocyte differentiation 0.974528 3091 renal water homeostasis 0.974503 5608 laminin-3 complex 0.974456 9231 riboflavin biosynthetic process 0.974407 8531 riboflavin kinase activity 0.974407 6771 riboflavin metabolic process 0.974407 16137 glycoside metabolic process 0.974391 51290 protein heterotetramerization 0.974382 32680 regulation of tumor necrosis factor production 0.974358 2829 negative regulation of T-helper 2 type immune response 0.974356 70228 regulation of lymphocyte apoptosis 0.974324 16557 peroxisome membrane biogenesis 0.974311 32581 ER-dependent peroxisome organization 0.974311 44091 membrane biogenesis 0.974311 44058 regulation of digestive system process 0.974310 60456 positive regulation of digestive system process 0.974309 50462 N-acetylneuraminate synthase activity 0.974262 47444 N-acylneuraminate-9-phosphate synthase activity 0.974262 19007 N-acylneuraminate-9-phosphate synthase activity 0.974262 31698 beta-2 adrenergic receptor binding 0.974261 2636 positive regulation of germinal center formation 0.974260 45993 negative regulation of translational initiation by iron 0.974214 46984 regulation of hemoglobin biosynthetic process 0.974214 46986 negative regulation of hemoglobin biosynthetic process 0.974214 45608 negative regulation of auditory receptor cell differentiation 0.974213 45632 negative regulation of mechanoreceptor differentiation 0.974213 60411 cardiac septum morphogenesis 0.974198 21892 cerebral cortex GABAergic interneuron differentiation 0.974166 21877 forebrain neuron fate commitment 0.974166 50795 regulation of behavior 0.974154 10885 regulation of cholesterol storage 0.974126 16730 oxidoreductase activity, acting on iron-sulfur proteins as donors 0.974118 16731 oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor 0.974118 4324 ferredoxin-NADP+ reductase activity 0.974118 8937 ferredoxin reductase activity 0.974118 31440 regulation of mRNA 3'-end processing 0.974116 48016 inositol phosphate-mediated signaling 0.974103 16241 regulation of macroautophagy 0.974099 32788 saturated monocarboxylic acid metabolic process 0.974069 32789 unsaturated monocarboxylic acid metabolic process 0.974069 46340 diacylglycerol catabolic process 0.974068 34404 nucleobase, nucleoside and nucleotide biosynthetic process 0.974051 34654 nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process 0.974051 43094 cellular metabolic compound salvage 0.974030 30581 symbiont intracellular protein transport in host 0.974021 51708 intracellular protein transport in other organism during symbiotic interaction 0.974021 19060 intracellular transport of viral proteins in host cell 0.974021 700 mismatch base pair DNA N-glycosylase activity 0.974020 6669 sphinganine-1-phosphate biosynthetic process 0.973973 46511 sphinganine biosynthetic process 0.973973 18993 somatic sex determination 0.973971 10559 regulation of glycoprotein biosynthetic process 0.973931 15682 ferric iron transport 0.973924 34755 iron ion transmembrane transport 0.973923 51004 regulation of lipoprotein lipase activity 0.973907 10837 regulation of keratinocyte proliferation 0.973876 10839 negative regulation of keratinocyte proliferation 0.973876 46887 positive regulation of hormone secretion 0.973869 3254 regulation of membrane depolarization 0.973852 30349 syntaxin-13 binding 0.973802 18017 peptidyl-arginine methylation 0.973793 35246 peptidyl-arginine N-methylation 0.973793 31081 nuclear pore distribution 0.973780 51664 nuclear pore localization 0.973780 31592 centrosomal corona 0.973731 10458 exit from mitosis 0.973731 4723 calcium-dependent protein serine/threonine phosphatase activity 0.973730 8600 protein serine/threonine phosphatase activity 0.973729 8598 protein serine/threonine phosphatase activity 0.973729 30357 protein serine/threonine phosphatase activity 0.973729 30358 protein serine/threonine phosphatase activity 0.973729 30361 protein serine/threonine phosphatase activity 0.973729 30360 protein serine/threonine phosphatase activity 0.973729 15071 protein serine/threonine phosphatase activity 0.973729 158 protein serine/threonine phosphatase activity 0.973729 163 protein serine/threonine phosphatase activity 0.973729 31057 negative regulation of histone modification 0.973725 45923 positive regulation of fatty acid metabolic process 0.973655 32328 alanine transport 0.973649 8420 CTD phosphatase activity 0.973635 33033 negative regulation of myeloid cell apoptosis 0.973619 19218 regulation of steroid metabolic process 0.973586 32427 GBD domain binding 0.973586 42481 regulation of odontogenesis 0.973562 42484 regulation of odontogenesis 0.973562 9076 histidine family amino acid biosynthetic process 0.973537 105 histidine biosynthetic process 0.973537 2286 T cell activation during immune response 0.973524 16635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor 0.973513 8177 succinate dehydrogenase (ubiquinone) activity 0.973513 19739 succinate dehydrogenase activity 0.973513 60561 apoptosis involved in morphogenesis 0.973490 7262 STAT protein nuclear translocation 0.973487 50999 regulation of nitric-oxide synthase activity 0.973473 6598 polyamine catabolic process 0.973416 7108 cytokinesis, initiation of separation 0.973393 915 cytokinesis, actomyosin contractile ring formation 0.973393 912 formation of actomyosin apparatus involved in cytokinesis 0.973393 70873 regulation of glycogen metabolic process 0.973371 32881 regulation of polysaccharide metabolic process 0.973371 48549 positive regulation of pinocytosis 0.973368 33628 regulation of cell adhesion mediated by integrin 0.973355 46349 amino sugar biosynthetic process 0.973344 48844 artery morphogenesis 0.973328 19673 GDP-mannose metabolic process 0.973295 8347 glial cell migration 0.973262 70626 (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity 0.973248 4018 N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity 0.973248 60080 regulation of inhibitory postsynaptic membrane potential 0.973230 70080 titin Z domain binding 0.973199 50921 positive regulation of chemotaxis 0.973160 46717 acid secretion 0.973152 43274 phospholipase binding 0.973148 4446 multiple inositol-polyphosphate phosphatase activity 0.973103 6797 polyphosphate metabolic process 0.973103 34417 bisphosphoglycerate 3-phosphatase activity 0.973103 46548 retinal rod cell development 0.973069 32210 regulation of telomere maintenance via telomerase 0.973065 42228 interleukin-8 biosynthetic process 0.973055 42304 regulation of fatty acid biosynthetic process 0.972998 50920 regulation of chemotaxis 0.972985 50728 negative regulation of inflammatory response 0.972977 60119 inner ear receptor cell development 0.972959 60117 auditory receptor cell development 0.972959 50869 negative regulation of B cell activation 0.972956 42534 regulation of tumor necrosis factor biosynthetic process 0.972913 43138 3'-5' DNA helicase activity 0.972870 30369 ICAM-3 receptor activity 0.972862 10595 positive regulation of endothelial cell migration 0.972841 48786 presynaptic active zone 0.972837 8783 agmatinase activity 0.972814 9445 putrescine metabolic process 0.972814 9446 putrescine biosynthetic process 0.972814 46671 negative regulation of retinal cell programmed cell death 0.972812 16155 formyltetrahydrofolate dehydrogenase activity 0.972811 30669 clathrin-coated endocytic vesicle membrane 0.972788 50254 rhodopsin kinase activity 0.972765 31663 lipopolysaccharide-mediated signaling pathway 0.972750 2700 regulation of production of molecular mediator of immune response 0.972737 31670 cellular response to nutrient 0.972723 6206 pyrimidine base metabolic process 0.972696 19405 alditol catabolic process 0.972682 48662 negative regulation of smooth muscle cell proliferation 0.972674 48305 immunoglobulin secretion 0.972669 21535 cell migration in hindbrain 0.972666 255 allantoin metabolic process 0.972665 2543 activation of blood coagulation via clotting cascade 0.972621 50918 positive chemotaxis 0.972586 44423 virion part 0.972572 19012 virion 0.972572 19031 viral envelope 0.972572 19028 viral capsid 0.972572 48242 epinephrine secretion 0.972524 48241 epinephrine transport 0.972524 50996 positive regulation of lipid catabolic process 0.972521 45777 positive regulation of blood pressure 0.972503 30628 pre-mRNA 3'-splice site binding 0.972476 386 second spliceosomal transesterification activity 0.972476 42104 positive regulation of activated T cell proliferation 0.972475 46173 polyol biosynthetic process 0.972451 16751 S-succinyltransferase activity 0.972427 4149 dihydrolipoyllysine-residue succinyltransferase activity 0.972427 45252 oxoglutarate dehydrogenase complex 0.972427 32925 regulation of activin receptor signaling pathway 0.972412 10623 developmental programmed cell death 0.972409 3922 GMP synthase (glutamine-hydrolyzing) activity 0.972379 3921 GMP synthase activity 0.972379 32649 regulation of interferon-gamma production 0.972346 15790 UDP-xylose transport 0.972331 5464 UDP-xylose transmembrane transporter activity 0.972331 45423 regulation of granulocyte macrophage colony-stimulating factor biosynthetic process 0.972327 32645 regulation of granulocyte macrophage colony-stimulating factor production 0.972327 6498 N-terminal protein lipidation 0.972296 48857 neural nucleus development 0.972284 51089 constitutive protein ectodomain proteolysis 0.972283 43647 inositol phosphate metabolic process 0.972280 32957 inositol trisphosphate metabolic process 0.972280 2312 B cell activation during immune response 0.972277 2313 mature B cell differentiation during immune response 0.972277 2335 mature B cell differentiation 0.972277 46640 regulation of alpha-beta T cell proliferation 0.972239 2069 columnar/cuboidal epithelial cell maturation 0.972234 2071 glandular epithelial cell maturation 0.972234 4781 sulfate adenylyltransferase (ATP) activity 0.972233 4779 sulfate adenylyltransferase activity 0.972233 4020 adenylylsulfate kinase activity 0.972233 6791 sulfur utilization 0.972233 19204 nucleotide phosphatase activity 0.972233 103 sulfate assimilation 0.972233 50431 transforming growth factor beta binding 0.972208 32455 nerve growth factor processing 0.972206 42112 T cell differentiation 0.972187 46652 T cell differentiation 0.972187 60333 interferon-gamma-mediated signaling pathway 0.972186 60337 type I interferon-mediated signaling pathway 0.972186 34340 response to type I interferon 0.972186 16260 selenocysteine biosynthetic process 0.972138 16259 selenocysteine metabolic process 0.972138 43437 butanoic acid metabolic process 0.972136 45618 positive regulation of keratinocyte differentiation 0.972103 45606 positive regulation of epidermal cell differentiation 0.972103 9113 purine base biosynthetic process 0.972057 45077 negative regulation of interferon-gamma biosynthetic process 0.972055 6863 purine transport 0.972038 32405 MutLalpha complex binding 0.972034 10812 negative regulation of cell-substrate adhesion 0.971981 1953 negative regulation of cell-matrix adhesion 0.971981 60986 endocrine hormone secretion 0.971943 32274 gonadotropin secretion 0.971943 32275 luteinizing hormone secretion 0.971943 46884 follicle-stimulating hormone secretion 0.971943 6011 UDP-glucose metabolic process 0.971919 2690 positive regulation of leukocyte chemotaxis 0.971918 2688 regulation of leukocyte chemotaxis 0.971918 4339 glucan 1,4-alpha-glucosidase activity 0.971896 5983 starch catabolic process 0.971896 5982 starch metabolic process 0.971896 16094 polyprenol biosynthetic process 0.971895 16091 prenol biosynthetic process 0.971895 19408 dolichol biosynthetic process 0.971895 45191 regulation of isotype switching 0.971894 2711 positive regulation of T cell mediated immunity 0.971891 51937 catecholamine transport 0.971840 60012 synaptic transmission, glycinergic 0.971822 35234 germ cell programmed cell death 0.971822 1550 ovarian cumulus expansion 0.971774 22605 oogenesis stage 0.971774 51952 regulation of amine transport 0.971768 48486 parasympathetic nervous system development 0.971751 21703 locus ceruleus development 0.971751 21523 somatic motor neuron differentiation 0.971751 50930 induction of positive chemotaxis 0.971745 33700 phospholipid efflux 0.971734 31441 negative regulation of mRNA 3'-end processing 0.971703 45343 regulation of MHC class I biosynthetic process 0.971700 8120 ceramide glucosyltransferase activity 0.971655 6679 glucosylceramide biosynthetic process 0.971655 30220 platelet formation 0.971653 46890 regulation of lipid biosynthetic process 0.971649 10800 positive regulation of peptidyl-threonine phosphorylation 0.971636 32509 endosome transport via multivesicular body sorting pathway 0.971636 9241 isoprenoid biosynthetic process 0.971611 2085 inhibition of neuroepithelial cell differentiation 0.971607 1831 trophectodermal cellular morphogenesis 0.971607 22408 negative regulation of cell-cell adhesion 0.971605 48261 negative regulation of receptor-mediated endocytosis 0.971572 60795 cell fate commitment involved in the formation of primary germ layers 0.971566 45014 negative regulation of transcription by glucose 0.971558 45013 negative regulation of transcription by carbon catabolites 0.971558 1974 blood vessel remodeling 0.971533 43874 acireductone synthase activity 0.971510 45821 positive regulation of glycolysis 0.971509 4662 CAAX-protein geranylgeranyltransferase activity 0.971509 42833 response to protozoan 0.971507 42832 defense response to protozoan 0.971507 70875 positive regulation of glycogen metabolic process 0.971461 35065 regulation of histone acetylation 0.971456 60229 lipase activator activity 0.971427 19238 cyclohydrolase activity 0.971427 45921 positive regulation of exocytosis 0.971418 2001 renin secretion into blood stream 0.971413 10962 regulation of glucan biosynthetic process 0.971413 32885 regulation of polysaccharide biosynthetic process 0.971413 5979 regulation of glycogen biosynthetic process 0.971413 51893 regulation of focal adhesion formation 0.971374 16842 amidine-lyase activity 0.971346 50702 interleukin-1 beta secretion 0.971340 50701 interleukin-1 secretion 0.971340 32612 interleukin-1 production 0.971340 48341 paraxial mesoderm formation 0.971276 31508 centromeric heterochromatin formation 0.971267 31507 heterochromatin formation 0.971267 70828 heterochromatin organization 0.971267 31501 mannosyltransferase complex 0.971266 18103 protein amino acid C-linked glycosylation 0.971266 18211 peptidyl-tryptophan modification 0.971266 18317 protein amino acid C-linked glycosylation via tryptophan 0.971266 18406 protein amino acid C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan 0.971266 35268 protein amino acid mannosylation 0.971266 35269 protein amino acid O-linked mannosylation 0.971266 51047 positive regulation of secretion 0.971221 42866 pyruvate biosynthetic process 0.971201 6568 tryptophan metabolic process 0.971197 32674 regulation of interleukin-5 production 0.971153 48103 somatic stem cell division 0.971147 17145 stem cell division 0.971147 32366 intracellular sterol transport 0.971144 32367 intracellular cholesterol transport 0.971144 51877 pigment granule aggregation in cell center 0.971137 8513 secondary active organic cation transmembrane transporter activity 0.971124 15201 monoamine transmembrane transporter activity 0.971089 2358 B cell homeostatic proliferation 0.971075 42114 B cell proliferation 0.971075 6111 regulation of gluconeogenesis 0.971060 48532 anatomical structure arrangement 0.971056 21612 facial nerve structural organization 0.971056 21604 cranial nerve structural organization 0.971056 17129 triglyceride binding 0.971027 32574 5'-3' RNA helicase activity 0.970979 32575 ATP-dependent 5'-3' RNA helicase activity 0.970979 45582 positive regulation of T cell differentiation 0.970952 70169 positive regulation of biomineral formation 0.970945 31179 peptide modification 0.970931 1519 peptide amidation 0.970931 16539 intein-mediated protein splicing 0.970929 32966 negative regulation of collagen biosynthetic process 0.970929 5113 patched binding 0.970929 30908 protein splicing 0.970929 48343 paraxial mesodermal cell fate commitment 0.970905 4349 glutamate 5-kinase activity 0.970882 4350 glutamate-5-semialdehyde dehydrogenase activity 0.970882 19202 amino acid kinase activity 0.970882 35243 protein-arginine omega-N symmetric methyltransferase activity 0.970881 2320 lymphoid progenitor cell differentiation 0.970877 2703 regulation of leukocyte mediated immunity 0.970861 30348 syntaxin-3 binding 0.970834 32103 positive regulation of response to external stimulus 0.970830 2705 positive regulation of leukocyte mediated immunity 0.970791 2708 positive regulation of lymphocyte mediated immunity 0.970791 51036 regulation of endosome size 0.970786 48821 erythrocyte development 0.970783 45621 positive regulation of lymphocyte differentiation 0.970765 2285 lymphocyte activation during immune response 0.970758 31641 regulation of myelination 0.970741 6361 transcription initiation from RNA polymerase I promoter 0.970737 3716 RNA polymerase I transcription termination factor activity 0.970737 42134 rRNA primary transcript binding 0.970737 4701 protein kinase C activity 0.970736 9609 response to symbiotic bacterium 0.970736 15222 serotonin transmembrane transporter activity 0.970689 5335 serotonin:sodium symporter activity 0.970689 33605 positive regulation of catecholamine secretion 0.970683 35189 Rb-E2F complex 0.970641 6107 oxaloacetate metabolic process 0.970639 4121 cystathionine beta-lyase activity 0.970592 4123 cystathionine gamma-lyase activity 0.970592 8160 protein tyrosine phosphatase activator activity 0.970567 32715 negative regulation of interleukin-6 production 0.970558 34046 poly(G) RNA binding 0.970544 5988 lactose metabolic process 0.970543 5989 lactose biosynthetic process 0.970543 46351 disaccharide biosynthetic process 0.970543 15067 amidinotransferase activity 0.970496 15068 glycine amidinotransferase activity 0.970496 2706 regulation of lymphocyte mediated immunity 0.970458 33182 regulation of histone ubiquitination 0.970448 70061 fructose binding 0.970431 21819 layer formation in the cerebral cortex 0.970429 46327 glycerol biosynthetic process from pyruvate 0.970399 32469 endoplasmic reticulum calcium ion homeostasis 0.970359 8310 single-stranded DNA specific 3'-5' exodeoxyribonuclease activity 0.970351 8859 exoribonuclease II activity 0.970351 10832 negative regulation of myotube differentiation 0.970316 10830 regulation of myotube differentiation 0.970316 51772 regulation of nitric-oxide synthase 2 biosynthetic process 0.970303 51773 positive regulation of nitric-oxide synthase 2 biosynthetic process 0.970303 45932 negative regulation of muscle contraction 0.970275 19211 phosphatase activator activity 0.970252 45620 negative regulation of lymphocyte differentiation 0.970248 70547 L-tyrosine aminotransferase activity 0.970206 4838 L-tyrosine:2-oxoglutarate aminotransferase activity 0.970206 50919 negative chemotaxis 0.970203 43438 acetoacetic acid metabolic process 0.970158 48701 embryonic cranial skeleton morphogenesis 0.970133 45354 regulation of interferon-alpha biosynthetic process 0.970123 48073 regulation of eye pigmentation 0.970110 48075 positive regulation of eye pigmentation 0.970110 42827 platelet dense granule 0.970110 32205 negative regulation of telomere maintenance 0.970069 5020 stem cell factor receptor activity 0.970061 30501 positive regulation of bone mineralization 0.970037 4833 tryptophan 2,3-dioxygenase activity 0.969987 46337 phosphatidylethanolamine metabolic process 0.969962 42941 D-alanine transport 0.969916 42942 D-serine transport 0.969916 8481 sphinganine kinase activity 0.969915 42117 monocyte activation 0.969901 45540 regulation of cholesterol biosynthetic process 0.969887 21546 rhombomere development 0.969877 35140 arm morphogenesis 0.969876 35117 embryonic arm morphogenesis 0.969876 48566 embryonic gut development 0.969866 50432 catecholamine secretion 0.969794 9415 response to water 0.969794 9414 response to water deprivation 0.969794 42631 cellular response to water deprivation 0.969794 46668 regulation of retinal cell programmed cell death 0.969785 31071 cysteine desulfurase activity 0.969772 43359 glial cell migration 0.969723 43615 astrocyte cell migration 0.969723 35284 brain segmentation 0.969720 15853 adenine transport 0.969675 19718 rough microsome 0.969675 21938 smoothened signaling pathway involved in regulation of granule cell precursor cell proliferation 0.969640 42789 mRNA transcription from RNA polymerase II promoter 0.969624 10870 positive regulation of receptor biosynthetic process 0.969598 6051 N-acetylmannosamine metabolic process 0.969578 6050 mannosamine metabolic process 0.969578 45127 N-acetylglucosamine kinase activity 0.969578 32411 positive regulation of transporter activity 0.969545 45836 positive regulation of meiosis 0.969482 9994 oocyte differentiation 0.969482 789 cytoplasmic chromatin 0.969482 32415 regulation of sodium:hydrogen antiporter activity 0.969447 4643 phosphoribosylaminoimidazolecarboxamide formyltransferase activity 0.969434 3937 IMP cyclohydrolase activity 0.969434 50727 regulation of inflammatory response 0.969433 70492 oligosaccharide binding 0.969432 33691 sialic acid binding 0.969432 33557 Slx1-Slx4 complex 0.969408 10792 DNA double-strand break processing involved in repair via single-strand annealing 0.969408 70229 negative regulation of lymphocyte apoptosis 0.969354 15193 L-proline transmembrane transporter activity 0.969350 5367 myo-inositol:sodium symporter activity 0.969337 5365 myo-inositol transmembrane transporter activity 0.969337 21562 vestibulocochlear nerve development 0.969336 10834 telomere maintenance via telomere shortening 0.969318 9258 10-formyltetrahydrofolate catabolic process 0.969311 9256 10-formyltetrahydrofolate metabolic process 0.969311 9397 folic acid and derivative catabolic process 0.969311 42560 pteridine and derivative catabolic process 0.969311 32467 positive regulation of cytokinesis 0.969289 10869 regulation of receptor biosynthetic process 0.969277 30300 regulation of intestinal cholesterol absorption 0.969272 4962 endothelin receptor activity 0.969263 16119 carotene metabolic process 0.969240 42214 terpene metabolic process 0.969240 33596 TSC1-TSC2 complex 0.969221 70328 triglyceride homeostasis 0.969206 43536 positive regulation of blood vessel endothelial cell migration 0.969201 3721 telomeric template RNA reverse transcriptase activity 0.969192 34505 tooth mineralization 0.969191 70666 regulation of mast cell proliferation 0.969178 30888 regulation of B cell proliferation 0.969178 50709 negative regulation of protein secretion 0.969145 33782 24-hydroxycholesterol 7alpha-hydroxylase activity 0.969144 8387 steroid 7-alpha-hydroxylase activity 0.969144 15556 C4-dicarboxylate transmembrane transporter activity 0.969142 31332 RNAi effector complex 0.969139 16442 RNA-induced silencing complex 0.969139 42522 regulation of tyrosine phosphorylation of Stat5 protein 0.969126 45725 positive regulation of glycogen biosynthetic process 0.969121 50895 circadian rhythm 0.969120 703 oxidized pyrimidine base lesion DNA N-glycosylase activity 0.969096 70198 protein localization to chromosome, telomeric region 0.969056 45499 chemorepellent activity 0.969047 2027 regulation of heart rate 0.969043 51281 positive regulation of release of sequestered calcium ion into cytosol 0.969032 31581 hemidesmosome assembly 0.968999 22617 extracellular matrix disassembly 0.968999 70728 leucine binding 0.968973 16639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor 0.968973 4353 glutamate dehydrogenase [NAD(P)+] activity 0.968973 4352 glutamate dehydrogenase activity 0.968973 32552 deoxyribonucleotide binding 0.968973 46607 positive regulation of centrosome cycle 0.968973 19459 glutamate deamidation 0.968973 8507 sodium:iodide symporter activity 0.968951 15705 iodide transport 0.968951 15373 monovalent anion:sodium symporter activity 0.968951 2637 regulation of immunoglobulin production 0.968938 30104 water homeostasis 0.968903 3975 UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity 0.968902 1553 luteinization 0.968883 6842 tricarboxylic acid transport 0.968867 15746 citrate transport 0.968867 15142 tricarboxylic acid transmembrane transporter activity 0.968867 15137 citrate transmembrane transporter activity 0.968867 70539 linoleic acid binding 0.968854 18208 peptidyl-proline modification 0.968853 18401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline 0.968853 6472 peptidyl-proline hydroxylation 0.968853 19471 4-hydroxyproline metabolic process 0.968853 19511 peptidyl-proline hydroxylation 0.968853 31282 regulation of guanylate cyclase activity 0.968851 45086 positive regulation of interleukin-2 biosynthetic process 0.968839 10871 negative regulation of receptor biosynthetic process 0.968838 10896 regulation of triglyceride catabolic process 0.968806 8615 pyridoxine biosynthetic process 0.968803 8614 pyridoxine metabolic process 0.968803 6773 pyridoxine metabolic process 0.968803 42816 vitamin B6 metabolic process 0.968803 42819 vitamin B6 biosynthetic process 0.968803 55090 acylglycerol homeostasis 0.968780 2066 columnar/cuboidal epithelial cell development 0.968709 395 nuclear mRNA 5'-splice site recognition 0.968661 48302 regulation of isotype switching to IgG isotypes 0.968616 42136 neurotransmitter biosynthetic process 0.968608 48934 peripheral nervous system neuron differentiation 0.968564 51355 proprioception during equilibrioception 0.968564 45717 negative regulation of fatty acid biosynthetic process 0.968560 45662 negative regulation of myoblast differentiation 0.968548 34103 regulation of tissue remodeling 0.968503 6704 glucocorticoid biosynthetic process 0.968481 46208 spermine catabolic process 0.968468 46592 polyamine oxidase activity 0.968468 32436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 0.968436 14829 vascular smooth muscle contraction 0.968412 51583 dopamine uptake 0.968371 51934 catecholamine uptake during transmission of nerve impulse 0.968371 48295 positive regulation of isotype switching to IgE isotypes 0.968346 8488 gamma-glutamyl carboxylase activity 0.968323 18214 protein amino acid carboxylation 0.968323 17187 peptidyl-glutamic acid carboxylation 0.968323 50648 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding 0.968275 50647 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding 0.968275 50646 5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid binding 0.968275 31056 regulation of histone modification 0.968232 51895 negative regulation of focal adhesion formation 0.968230 33819 lipoyl(octanoyl) transferase activity 0.968226 32653 regulation of interleukin-10 production 0.968209 43255 regulation of carbohydrate biosynthetic process 0.968206 51265 diolein transacylation activity 0.968178 51264 mono-olein transacylation activity 0.968178 9296 flagellum assembly 0.968143 43064 flagellum organization 0.968143 50922 negative regulation of chemotaxis 0.968130 6166 purine ribonucleoside salvage 0.968125 43174 nucleoside salvage 0.968125 32414 positive regulation of ion transmembrane transporter activity 0.968083 45589 regulation of regulatory T cell differentiation 0.968080 43198 dendritic shaft 0.968065 10676 positive regulation of cellular carbohydrate metabolic process 0.968046 45913 positive regulation of carbohydrate metabolic process 0.968046 10522 regulation of calcium ion transport into cytosol 0.968038 43426 MRF binding 0.968033 51577 MyoD binding 0.968033 33037 polysaccharide localization 0.967985 32792 negative regulation of CREB transcription factor activity 0.967983 50864 regulation of B cell activation 0.967976 32377 regulation of intracellular lipid transport 0.967937 32383 regulation of intracellular cholesterol transport 0.967937 32380 regulation of intracellular sterol transport 0.967937 70528 protein kinase C signaling cascade 0.967911 70493 thrombin receptor signaling pathway 0.967911 45907 positive regulation of vasoconstriction 0.967896 30288 outer membrane-bounded periplasmic space 0.967888 42597 periplasmic space 0.967888 5620 periplasmic space 0.967888 60077 inhibitory synapse 0.967840 15495 gamma-aminobutyric acid:hydrogen symporter activity 0.967840 5677 chromatin silencing complex 0.967821 4923 leukemia inhibitory factor receptor activity 0.967814 3014 renal system process 0.967789 50902 leukocyte adhesive activation 0.967743 51040 regulation of calcium-independent cell-cell adhesion 0.967743 51041 positive regulation of calcium-independent cell-cell adhesion 0.967743 10907 positive regulation of glucose metabolic process 0.967721 6616 SRP-dependent cotranslational protein targeting to membrane, translocation 0.967695 6617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition 0.967695 2051 osteoblast fate commitment 0.967694 16139 glycoside catabolic process 0.967692 45599 negative regulation of fat cell differentiation 0.967679 31343 positive regulation of cell killing 0.967675 4648 O-phospho-L-serine:2-oxoglutarate aminotransferase activity 0.967647 32755 positive regulation of interleukin-6 production 0.967627 6021 inositol biosynthetic process 0.967612 51900 regulation of mitochondrial depolarization 0.967606 16560 protein import into peroxisome matrix, docking 0.967599 2542 Factor XII activation 0.967597 10954 positive regulation of protein maturation by peptide bond cleavage 0.967597 32677 regulation of interleukin-8 production 0.967561 18872 arsonoacetate metabolic process 0.967454 30791 arsenite methyltransferase activity 0.967454 30792 methylarsonite methyltransferase activity 0.967454 33257 Bcl3/NF-kappaB2 complex 0.967452 2268 follicular dendritic cell differentiation 0.967452 2266 follicular dendritic cell activation 0.967452 51353 positive regulation of oxidoreductase activity 0.967418 44462 external encapsulating structure part 0.967402 4651 polynucleotide 5'-phosphatase activity 0.967357 4484 mRNA guanylyltransferase activity 0.967357 42629 mast cell granule 0.967356 2702 positive regulation of production of molecular mediator of immune response 0.967312 32720 negative regulation of tumor necrosis factor production 0.967298 50729 positive regulation of inflammatory response 0.967278 42634 regulation of hair cycle 0.967274 51797 regulation of hair follicle development 0.967274 51240 positive regulation of multicellular organismal process 0.967248 32713 negative regulation of interleukin-4 production 0.967225 1980 regulation of systemic arterial blood pressure by ischemic conditions 0.967212 32845 negative regulation of homeostatic process 0.967189 45275 respiratory chain complex III 0.967187 45285 respiratory chain complex III 0.967187 32842 respiratory chain complex III 0.967187 5750 mitochondrial respiratory chain complex III 0.967187 21766 hippocampus development 0.967161 32204 regulation of telomere maintenance 0.967147 46149 pigment catabolic process 0.967145 42167 heme catabolic process 0.967145 50653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process 0.967138 1660 fever 0.967138 47237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity 0.967138 7522 visceral muscle development 0.967116 45684 positive regulation of epidermis development 0.967092 46160 heme a metabolic process 0.967090 6123 mitochondrial electron transport, cytochrome c to oxygen 0.967090 6784 heme a biosynthetic process 0.967090 2366 leukocyte activation during immune response 0.967078 2263 cell activation during immune response 0.967078 34774 secretory granule lumen 0.967067 34466 chromaffin granule lumen 0.967067 45089 positive regulation of innate immune response 0.967042 48637 skeletal muscle tissue development 0.967042 6287 base-excision repair, gap-filling 0.967042 31349 positive regulation of defense response 0.967037 48243 norepinephrine secretion 0.967019 15874 norepinephrine transport 0.967019 702 oxidized base lesion DNA N-glycosylase activity 0.967018 21895 cerebral cortex neuron differentiation 0.967016 48667 cell morphogenesis involved in neuron differentiation 0.967014 5218 intracellular ligand-gated calcium channel activity 0.967003 5219 ryanodine-sensitive calcium-release channel activity 0.967003 3979 UDP-glucose 6-dehydrogenase activity 0.966971 15781 pyrimidine nucleotide-sugar transport 0.966897 800 lateral element 0.966870 45079 negative regulation of chemokine biosynthetic process 0.966855 46479 glycosphingolipid catabolic process 0.966837 19377 glycolipid catabolic process 0.966837 42523 positive regulation of tyrosine phosphorylation of Stat5 protein 0.966835 48304 positive regulation of isotype switching to IgG isotypes 0.966833 15319 sodium:inorganic phosphate symporter activity 0.966826 42137 sequestering of neurotransmitter 0.966826 8340 determination of adult lifespan 0.966810 4852 uroporphyrinogen-III synthase activity 0.966778 6780 uroporphyrinogen III biosynthetic process 0.966778 46502 uroporphyrinogen III metabolic process 0.966778 60039 pericardium development 0.966776 60429 epithelium development 0.966776 33015 tetrapyrrole catabolic process 0.966761 46174 polyol catabolic process 0.966761 6787 porphyrin catabolic process 0.966761 46683 response to organophosphorus 0.966749 17085 response to insecticide 0.966749 17108 5'-flap endonuclease activity 0.966700 35084 flagellar axoneme assembly 0.966655 7288 sperm axoneme assembly 0.966655 34339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor 0.966655 45429 positive regulation of nitric oxide biosynthetic process 0.966651 33205 cytokinesis during cell cycle 0.966637 16288 cytokinesis 0.966637 7104 cytokinesis 0.966637 50871 positive regulation of B cell activation 0.966602 45908 negative regulation of vasodilation 0.966597 51013 microtubule severing 0.966585 7109 cytokinesis, completion of separation 0.966585 19934 cGMP-mediated signaling 0.966499 48787 presynaptic active zone membrane 0.966488 7614 short-term memory 0.966488 15226 carnitine transporter activity 0.966485 15202 quaternary ammonium group transmembrane transporter activity 0.966485 2230 positive regulation of defense response to virus by host 0.966462 34134 toll-like receptor 2 signaling pathway 0.966462 45869 negative regulation of retroviral genome replication 0.966462 6410 transcription, RNA-dependent 0.966462 10383 cell wall polysaccharide metabolic process 0.966440 6037 cell wall chitin metabolic process 0.966440 1920 negative regulation of receptor recycling 0.966414 48660 regulation of smooth muscle cell proliferation 0.966401 45577 regulation of B cell differentiation 0.966371 45428 regulation of nitric oxide biosynthetic process 0.966347 45209 MAPK phosphatase export from nucleus, leptomycin B sensitive 0.966343 45204 MAPK export from nucleus 0.966343 45208 MAPK phosphatase export from nucleus 0.966343 50807 regulation of synapse organization 0.966285 42108 positive regulation of cytokine biosynthetic process 0.966282 3016 respiratory system process 0.966250 45007 depurination 0.966243 10508 positive regulation of autophagy 0.966198 16239 positive regulation of macroautophagy 0.966198 4379 glycylpeptide N-tetradecanoyltransferase activity 0.966197 18377 protein myristoylation 0.966197 18319 protein amino acid myristoylation 0.966197 6499 N-terminal protein myristoylation 0.966197 19107 myristoyltransferase activity 0.966197 4639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity 0.966150 4638 phosphoribosylaminoimidazole carboxylase activity 0.966150 70918 production of small RNA involved in gene silencing by RNA 0.966131 31050 dsRNA fragmentation 0.966131 30422 production of siRNA involved in RNA interference 0.966131 71359 cellular response to dsRNA 0.966131 4102 choline O-acetyltransferase activity 0.966102 21696 cerebellar cortex morphogenesis 0.966098 2062 chondrocyte differentiation 0.966057 8750 NAD(P)+ transhydrogenase (AB-specific) activity 0.966053 3957 NAD(P)+ transhydrogenase (B-specific) activity 0.966053 50746 regulation of lipoprotein metabolic process 0.966050 10888 negative regulation of lipid storage 0.966031 31210 phosphatidylcholine binding 0.966013 8620 condensin complex 0.965957 799 nuclear condensin complex 0.965957 5676 condensin complex 0.965957 34366 spherical high-density lipoprotein particle 0.965927 4585 ornithine carbamoyltransferase activity 0.965909 9348 ornithine carbamoyltransferase complex 0.965909 45056 transcytosis 0.965860 51385 response to mineralocorticoid stimulus 0.965860 50707 regulation of cytokine secretion 0.965842 32388 positive regulation of intracellular transport 0.965835 10243 response to organic nitrogen 0.965829 14075 response to amine stimulus 0.965829 405 bubble DNA binding 0.965819 17050 D-erythro-sphingosine kinase activity 0.965812 60347 heart trabecula formation 0.965804 15852 purine transport 0.965786 43029 T cell homeostasis 0.965778 10509 polyamine homeostasis 0.965764 33754 indoleamine 2,3-dioxygenase activity 0.965762 50879 multicellular organismal movement 0.965760 50881 musculoskeletal movement 0.965760 50221 prostaglandin-E2 9-reductase activity 0.965715 47021 15-hydroxyprostaglandin dehydrogenase (NADP+) activity 0.965715 42373 vitamin K metabolic process 0.965715 6848 pyruvate transport 0.965667 50833 pyruvate transmembrane transporter activity 0.965667 5477 pyruvate secondary active transmembrane transporter activity 0.965667 32091 negative regulation of protein binding 0.965664 46827 positive regulation of protein export from nucleus 0.965664 30857 negative regulation of epithelial cell differentiation 0.965650 32212 positive regulation of telomere maintenance via telomerase 0.965648 1992 regulation of systemic arterial blood pressure by vasopressin 0.965641 43497 regulation of protein heterodimerization activity 0.965638 42428 serotonin metabolic process 0.965638 42026 protein refolding 0.965631 8291 acetylcholine metabolic process 0.965615 15194 L-serine transmembrane transporter activity 0.965583 32329 serine transport 0.965583 22889 serine transmembrane transporter activity 0.965583 42489 negative regulation of odontogenesis of dentine-containing tooth 0.965571 42486 negative regulation of odontogenesis 0.965571 2028 regulation of sodium ion transport 0.965551 46218 indolalkylamine catabolic process 0.965525 6569 tryptophan catabolic process 0.965525 42436 indole derivative catabolic process 0.965525 33345 asparagine catabolic process via L-aspartate 0.965522 6530 asparagine catabolic process 0.965522 51354 negative regulation of oxidoreductase activity 0.965520 48762 mesenchymal cell differentiation 0.965519 1975 response to amphetamine 0.965511 782 telomere cap complex 0.965498 783 nuclear telomere cap complex 0.965498 9384 N-acylmannosamine kinase activity 0.965496 32855 positive regulation of Rac GTPase activity 0.965493 6789 bilirubin conjugation 0.965474 18879 biphenyl metabolic process 0.965474 48841 regulation of axon extension involved in axon guidance 0.965424 48843 negative regulation of axon extension involved in axon guidance 0.965424 8309 double-stranded DNA specific exodeoxyribonuclease activity 0.965424 32908 regulation of transforming growth factor-beta1 production 0.965422 2825 regulation of T-helper 1 type immune response 0.965421 46968 peptide antigen transport 0.965352 46795 intracellular virion transport 0.965352 46794 virion transport 0.965352 19062 virion attachment to host cell surface receptor 0.965352 34105 positive regulation of tissue remodeling 0.965348 51930 regulation of sensory perception of pain 0.965336 51931 regulation of sensory perception 0.965336 9298 GDP-mannose biosynthetic process 0.965329 4477 methenyltetrahydrofolate cyclohydrolase activity 0.965310 4486 methylenetetrahydrofolate dehydrogenase activity 0.965310 16108 tetraterpenoid metabolic process 0.965310 16116 carotenoid metabolic process 0.965310 717 nucleotide-excision repair, DNA duplex unwinding 0.965281 70411 I-SMAD binding 0.965256 45091 regulation of retroviral genome replication 0.965252 34729 histone H3-K79 methylation 0.965233 51568 histone H3-K4 methylation 0.965233 35300 inositol-1,3,4-trisphosphate 5/6-kinase activity 0.965184 47325 inositol tetrakisphosphate 1-kinase activity 0.965184 50714 positive regulation of protein secretion 0.965145 30327 prenylated protein catabolic process 0.965136 1735 prenylcysteine oxidase activity 0.965136 19852 L-ascorbic acid metabolic process 0.965100 5984 disaccharide metabolic process 0.965091 1844 protein insertion into mitochondrial membrane during induction of apoptosis 0.965088 34629 cellular protein complex localization 0.965084 50997 quaternary ammonium group binding 0.965043 45554 regulation of TRAIL biosynthetic process 0.964991 45556 positive regulation of TRAIL biosynthetic process 0.964991 32679 regulation of TRAIL production 0.964991 42975 peroxisome proliferator activated receptor binding 0.964989 43531 ADP binding 0.964969 43754 dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity 0.964943 46949 acyl-CoA biosynthetic process 0.964943 8534 oxidized purine base lesion DNA N-glycosylase activity 0.964894 32510 endosome to lysosome transport via multivesicular body sorting pathway 0.964893 8445 D-aspartate oxidase activity 0.964846 15922 aspartate oxidase activity 0.964846 48296 regulation of isotype switching to IgA isotypes 0.964845 48298 positive regulation of isotype switching to IgA isotypes 0.964845 21912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification 0.964845 19430 removal of superoxide radicals 0.964830 8608 attachment of spindle microtubules to kinetochore 0.964820 51313 attachment of spindle microtubules to chromosome 0.964820 42795 snRNA transcription from RNA polymerase II promoter 0.964798 42796 snRNA transcription from RNA polymerase III promoter 0.964798 19185 snRNA-activating protein complex 0.964798 3941 L-serine ammonia-lyase activity 0.964772 71214 cellular response to abiotic stimulus 0.964750 71470 cellular response to osmotic stress 0.964750 7231 osmosensory signaling pathway 0.964750 30240 muscle thin filament assembly 0.964743 14902 myotube differentiation 0.964714 212 meiotic spindle organization 0.964714 30233 deoxynucleotide transmembrane transporter activity 0.964701 30302 deoxynucleotide transport 0.964701 15215 nucleotide transmembrane transporter activity 0.964701 1912 positive regulation of leukocyte mediated cytotoxicity 0.964699 50810 regulation of steroid biosynthetic process 0.964683 35197 siRNA binding 0.964666 4671 protein-S-isoprenylcysteine O-methyltransferase activity 0.964653 6982 response to lipid hydroperoxide 0.964651 6106 fumarate metabolic process 0.964617 2793 positive regulation of peptide secretion 0.964594 60343 trabecula formation 0.964574 43218 compact myelin 0.964556 42759 long-chain fatty acid biosynthetic process 0.964556 47718 indanol dehydrogenase activity 0.964555 51222 positive regulation of protein transport 0.964511 33693 neurofilament bundle assembly 0.964508 1875 lipopolysaccharide receptor activity 0.964492 14705 C zone 0.964460 60047 heart contraction 0.964455 3015 heart process 0.964455 32695 negative regulation of interleukin-12 production 0.964453 45842 positive regulation of mitotic metaphase/anaphase transition 0.964434 15881 creatine transport 0.964412 5309 creatine:sodium symporter activity 0.964412 5308 creatine transporter activity 0.964412 4325 ferrochelatase activity 0.964315 9589 detection of UV 0.964315 32222 regulation of synaptic transmission, cholinergic 0.964289 45063 T-helper 1 cell differentiation 0.964267 4488 methylenetetrahydrofolate dehydrogenase (NADP+) activity 0.964265 9068 aspartate family amino acid catabolic process 0.964186 229 cytoplasmic chromosome 0.964170 262 mitochondrial chromosome 0.964170 4660 protein farnesyltransferase activity 0.964168 18347 protein amino acid farnesylation 0.964168 35312 5'-3' exodeoxyribonuclease activity 0.964168 42130 negative regulation of T cell proliferation 0.964162 35042 fertilization, exchange of chromosomal proteins 0.964122 46501 protoporphyrinogen IX metabolic process 0.964120 45685 regulation of glial cell differentiation 0.964083 14013 regulation of gliogenesis 0.964083 6538 glutamate catabolic process 0.964057 10743 regulation of macrophage derived foam cell differentiation 0.964040 60158 activation of phospholipase C activity by dopamine receptor signaling pathway 0.964028 9236 cobalamin biosynthetic process 0.964025 9235 cobalamin metabolic process 0.964025 8817 cob(I)yrinic acid a,c-diamide adenosyltransferase activity 0.964025 32434 regulation of proteasomal ubiquitin-dependent protein catabolic process 0.964010 34374 low-density lipoprotein particle remodeling 0.964006 45673 regulation of photoreceptor cell differentiation 0.963999 46532 regulation of photoreceptor cell differentiation 0.963999 6713 glucocorticoid catabolic process 0.963977 9225 nucleotide-sugar metabolic process 0.963955 1696 gastric acid secretion 0.963929 32202 telomere assembly 0.963922 16415 octanoyltransferase activity 0.963903 43137 DNA replication, removal of RNA primer 0.963903 43195 terminal button 0.963891 6782 protoporphyrinogen IX biosynthetic process 0.963880 30350 iron-responsive element binding 0.963880 3032 detection of oxygen 0.963877 9261 ribonucleotide catabolic process 0.963856 10828 positive regulation of glucose transport 0.963851 46326 positive regulation of glucose import 0.963851 42402 cellular biogenic amine catabolic process 0.963848 50124 N-acylneuraminate-9-phosphatase activity 0.963832 46380 N-acetylneuraminate biosynthetic process 0.963832 45714 regulation of low-density lipoprotein receptor biosynthetic process 0.963815 45911 positive regulation of DNA recombination 0.963808 45830 positive regulation of isotype switching 0.963808 33753 establishment of ribosome localization 0.963784 54 ribosomal subunit export from nucleus 0.963784 56 ribosomal small subunit export from nucleus 0.963784 16840 carbon-nitrogen lyase activity 0.963778 51971 positive regulation of transmission of nerve impulse 0.963727 34502 protein localization to chromosome 0.963725 70577 histone acetyl-lysine binding 0.963718 50854 regulation of antigen receptor-mediated signaling pathway 0.963705 6536 glutamate metabolic process 0.963695 32863 activation of Rac GTPase activity 0.963684 31330 negative regulation of cellular catabolic process 0.963676 2720 positive regulation of cytokine production during immune response 0.963669 50686 negative regulation of mRNA processing 0.963668 70296 sarcoplasmic reticulum calcium ion transport 0.963661 45198 establishment of epithelial cell apical/basal polarity 0.963661 90162 establishment of epithelial cell polarity 0.963661 30859 polarized epithelial cell differentiation 0.963661 32365 intracellular lipid transport 0.963649 15651 quaternary ammonium group transmembrane transporter activity 0.963646 5163 nerve growth factor receptor binding 0.963639 46321 positive regulation of fatty acid oxidation 0.963614 18200 peptidyl-glutamic acid modification 0.963613 21545 cranial nerve development 0.963601 4096 catalase activity 0.963591 15782 CMP-sialic acid transport 0.963542 5456 CMP-sialic acid transmembrane transporter activity 0.963542 15809 arginine transport 0.963539 3097 renal water transport 0.963494 43102 amino acid salvage 0.963468 71267 L-methionine salvage 0.963468 71265 L-methionine biosynthetic process 0.963468 19509 L-methionine salvage from methylthioadenosine 0.963468 51048 negative regulation of secretion 0.963452 51106 positive regulation of DNA ligation 0.963446 51105 regulation of DNA ligation 0.963446 6370 mRNA capping 0.963441 15788 UDP-N-acetylglucosamine transport 0.963420 5462 UDP-N-acetylglucosamine transmembrane transporter activity 0.963420 16623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor 0.963372 4031 aldehyde oxidase activity 0.963372 6655 phosphatidylglycerol biosynthetic process 0.963372 15825 L-serine transport 0.963372 32048 cardiolipin metabolic process 0.963372 32049 cardiolipin biosynthetic process 0.963372 46471 phosphatidylglycerol metabolic process 0.963372 50748 negative regulation of lipoprotein metabolic process 0.963357 43790 rRNA (adenine-N6,N6-)-dimethyltransferase activity 0.963349 60272 embryonic skeletal joint morphogenesis 0.963347 31341 regulation of cell killing 0.963325 31060 regulation of histone methylation 0.963320 45779 negative regulation of bone resorption 0.963308 46851 negative regulation of bone remodeling 0.963308 4452 isopentenyl-diphosphate delta-isomerase activity 0.963299 16109 tetraterpenoid biosynthetic process 0.963299 16117 carotenoid biosynthetic process 0.963299 16114 terpenoid biosynthetic process 0.963299 45359 positive regulation of interferon-beta biosynthetic process 0.963296 45356 positive regulation of interferon-alpha biosynthetic process 0.963296 45357 regulation of interferon-beta biosynthetic process 0.963296 32648 regulation of interferon-beta production 0.963296 9111 vitamin catabolic process 0.963255 32418 lysosome localization 0.963233 42806 fucose binding 0.963227 30856 regulation of epithelial cell differentiation 0.963224 47840 dCTP diphosphatase activity 0.963204 32556 pyrimidine deoxyribonucleotide binding 0.963204 43903 regulation of symbiosis, encompassing mutualism through parasitism 0.963203 46596 regulation of virion penetration into host cell 0.963203 18348 protein amino acid geranylgeranylation 0.963201 46040 IMP metabolic process 0.963187 6188 IMP biosynthetic process 0.963187 6189 'de novo' IMP biosynthetic process 0.963187 15665 alcohol transmembrane transporter activity 0.963175 15166 polyol transmembrane transporter activity 0.963175 21953 central nervous system neuron differentiation 0.963120 15392 nucleobase transmembrane transporter activity 0.963115 5345 purine transmembrane transporter activity 0.963115 10898 positive regulation of triglyceride catabolic process 0.963110 15637 peptide transporter activity 0.963067 16841 ammonia-lyase activity 0.963066 7386 compartment specification 0.963056 43178 alcohol binding 0.963025 35265 organ growth 0.963006 35067 negative regulation of histone acetylation 0.962992 32135 DNA insertion or deletion binding 0.962985 31493 nucleosomal histone binding 0.962963 32093 SAM domain binding 0.962963 48386 positive regulation of retinoic acid receptor signaling pathway 0.962937 32154 cleavage furrow 0.962908 42257 ribosomal subunit assembly 0.962866 28 ribosomal small subunit assembly 0.962866 17061 S-methyl-5-thioadenosine phosphorylase activity 0.962818 33198 response to ATP 0.962814 32506 cytokinetic process 0.962813 8554 sodium-exporting ATPase activity, phosphorylative mechanism 0.962770 15432 bile acid-exporting ATPase activity 0.962770 1710 mesodermal cell fate commitment 0.962766 46824 positive regulation of nucleocytoplasmic transport 0.962748 46503 glycerolipid catabolic process 0.962745 1776 leukocyte homeostasis 0.962724 16618 hydroxypyruvate reductase activity 0.962722 8465 glycerate dehydrogenase activity 0.962722 30267 glyoxylate reductase (NADP) activity 0.962722 16726 oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor 0.962720 4854 xanthine dehydrogenase activity 0.962720 2717 positive regulation of natural killer cell mediated immunity 0.962699 45846 positive regulation of natural killer cell mediated immunity 0.962699 45954 positive regulation of natural killer cell mediated cytotoxicity 0.962699 48661 positive regulation of smooth muscle cell proliferation 0.962673 7622 rhythmic behavior 0.962662 51103 DNA ligation during DNA repair 0.962656 45956 positive regulation of calcium ion-dependent exocytosis 0.962647 5165 neurotrophin receptor binding 0.962647 43257 laminin-8 complex 0.962625 5607 laminin-2 complex 0.962625 6054 N-acetylneuraminate metabolic process 0.962623 42412 taurine biosynthetic process 0.962577 17172 cysteine dioxygenase activity 0.962577 43141 ATP-dependent 5'-3' DNA helicase activity 0.962573 32025 response to cobalt ion 0.962528 51990 (R)-2-hydroxyglutarate dehydrogenase activity 0.962528 50046 lathosterol oxidase activity 0.962480 46996 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NADH or NADPH as one donor, and the other dehydrogenated 0.962480 45076 regulation of interleukin-2 biosynthetic process 0.962480 4807 triose-phosphate isomerase activity 0.962432 19682 glyceraldehyde-3-phosphate metabolic process 0.962432 21942 radial glia guided migration of Purkinje cell 0.962384 31117 positive regulation of microtubule depolymerization 0.962335 8352 katanin complex 0.962335 16647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor 0.962309 42276 error-prone translesion synthesis 0.962287 19985 translesion synthesis 0.962287 17125 deoxycytidyl transferase activity 0.962287 32226 positive regulation of synaptic transmission, dopaminergic 0.962261 18205 peptidyl-lysine modification 0.962255 1973 adenosine receptor signaling pathway 0.962239 21754 facial nucleus development 0.962237 21570 rhombomere 4 development 0.962237 19814 immunoglobulin complex 0.962237 19815 B cell receptor complex 0.962237 22029 telencephalon cell migration 0.962213 4925 prolactin receptor activity 0.962190 4314 [acyl-carrier-protein] S-malonyltransferase activity 0.962189 16419 S-malonyltransferase activity 0.962189 16420 malonyltransferase activity 0.962189 45617 negative regulation of keratinocyte differentiation 0.962142 45605 negative regulation of epidermal cell differentiation 0.962142 70189 kynurenine metabolic process 0.962094 4502 kynurenine 3-monooxygenase activity 0.962094 51315 attachment of spindle microtubules to kinetochore during mitosis 0.962045 16855 racemase and epimerase activity, acting on amino acids and derivatives 0.962044 47661 amino-acid racemase activity 0.962044 6014 D-ribose metabolic process 0.962042 5286 basic amino acid transmembrane transporter activity 0.962042 1819 positive regulation of cytokine production 0.962040 33146 regulation of estrogen receptor signaling pathway 0.961997 33147 negative regulation of estrogen receptor signaling pathway 0.961997 45625 regulation of T-helper 1 cell differentiation 0.961994 21874 Wnt receptor signaling pathway in forebrain neuroblast division 0.961949 31331 positive regulation of cellular catabolic process 0.961944 60759 regulation of response to cytokine stimulus 0.961929 10675 regulation of cellular carbohydrate metabolic process 0.961923 17127 cholesterol transporter activity 0.961921 46628 positive regulation of insulin receptor signaling pathway 0.961919 1101 response to acid 0.961918 16554 cytidine to uridine editing 0.961901 15747 urate transport 0.961852 15143 urate transmembrane transporter activity 0.961852 2685 regulation of leukocyte migration 0.961835 51972 regulation of telomerase activity 0.961827 1599 endothelin-A receptor activity 0.961707 51305 chromosome movement towards spindle pole 0.961704 42219 cellular amino acid derivative catabolic process 0.961627 50806 positive regulation of synaptic transmission 0.961622 46713 boron transport 0.961563 46715 boron transporter activity 0.961563 50856 regulation of T cell receptor signaling pathway 0.961462 55006 cardiac cell development 0.961459 55013 cardiac muscle cell development 0.961459 70668 positive regulation of mast cell proliferation 0.961445 30890 positive regulation of B cell proliferation 0.961445 16004 phospholipase activator activity 0.961430 51896 regulation of protein kinase B signaling cascade 0.961427 31856 parathyroid hormone receptor binding 0.961418 51050 positive regulation of transport 0.961395 15248 sterol transporter activity 0.961383 8761 UDP-N-acetylglucosamine 2-epimerase activity 0.961369 2328 pro-B cell differentiation 0.961366 50706 regulation of interleukin-1 beta secretion 0.961349 31296 B cell costimulation 0.961343 51765 inositol tetrakisphosphate kinase activity 0.961343 60192 negative regulation of lipase activity 0.961331 51891 positive regulation of cardioblast differentiation 0.961303 51890 regulation of cardioblast differentiation 0.961303 31646 positive regulation of neurological system process 0.961290 48149 behavioral response to ethanol 0.961285 17036 response to ethanol 0.961285 18190 protein amino acid octanoylation 0.961273 18191 peptidyl-serine octanoylation 0.961273 16412 serine O-acyltransferase activity 0.961273 221 vacuolar proton-transporting V-type ATPase, V1 domain 0.961225 90174 organelle membrane fusion 0.961199 16090 prenol metabolic process 0.961195 16093 polyprenol metabolic process 0.961195 19348 dolichol metabolic process 0.961195 16908 MAP kinase 2 activity 0.961176 31434 mitogen-activated protein kinase kinase binding 0.961128 48070 regulation of pigmentation during development 0.961103 6768 biotin metabolic process 0.961080 45072 regulation of interferon-gamma biosynthetic process 0.961065 32231 regulation of actin filament bundle formation 0.961043 46963 3'-phosphoadenosine 5'-phosphosulfate transport 0.961031 46964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity 0.961031 30469 maintenance of cell polarity 0.961005 30013 maintenance of cell polarity 0.961005 30011 maintenance of cell polarity 0.961005 35090 maintenance of apical/basal cell polarity 0.961005 43279 response to alkaloid 0.961001 48641 regulation of skeletal muscle tissue development 0.960997 47017 prostaglandin-F synthase activity 0.960983 48625 myoblast cell fate commitment 0.960981 42423 catecholamine biosynthetic process 0.960973 48808 male genitalia morphogenesis 0.960935 30235 nitric-oxide synthase regulator activity 0.960918 33011 perinuclear theca 0.960887 35039 male pronucleus formation 0.960887 7343 egg activation 0.960887 51148 negative regulation of muscle cell differentiation 0.960862 10521 telomerase inhibitor activity 0.960851 32042 mitochondrial DNA metabolic process 0.960840 42799 histone methyltransferase activity (H4-K20 specific) 0.960838 46975 histone methyltransferase activity (H3-K36 specific) 0.960838 9263 deoxyribonucleotide biosynthetic process 0.960837 33627 cell adhesion mediated by integrin 0.960831 6668 sphinganine-1-phosphate metabolic process 0.960788 6667 sphinganine metabolic process 0.960788 48385 regulation of retinoic acid receptor signaling pathway 0.960772 5760 gamma DNA polymerase complex 0.960764 42129 regulation of T cell proliferation 0.960743 4334 fumarylacetoacetase activity 0.960742 33603 positive regulation of dopamine secretion 0.960706 50715 positive regulation of cytokine secretion 0.960694 4513 neolactotetraosylceramide alpha-2,3-sialyltransferase activity 0.960693 47291 lactosylceramide alpha-2,3-sialyltransferase activity 0.960693 45619 regulation of lymphocyte differentiation 0.960690 48596 embryonic camera-type eye morphogenesis 0.960688 97 sulfur amino acid biosynthetic process 0.960671 43331 response to dsRNA 0.960657 60032 notochord regression 0.960645 46168 glycerol-3-phosphate catabolic process 0.960619 4367 glycerol-3-phosphate dehydrogenase (NAD+) activity 0.960619 19563 glycerol catabolic process 0.960619 51798 positive regulation of hair follicle development 0.960603 46696 lipopolysaccharide receptor complex 0.960570 50764 regulation of phagocytosis 0.960552 4876 complement component C3a receptor activity 0.960549 4943 C3a anaphylatoxin receptor activity 0.960549 43011 myeloid dendritic cell differentiation 0.960539 1773 myeloid dendritic cell activation 0.960539 15816 glycine transport 0.960529 5280 hydrogen:amino acid symporter activity 0.960529 9021 tRNA (uracil-5-)-methyltransferase activity 0.960500 16300 tRNA (uracil) methyltransferase activity 0.960500 16431 tRNA (uracil) methyltransferase activity 0.960500 35304 regulation of protein amino acid dephosphorylation 0.960483 48712 negative regulation of astrocyte differentiation 0.960474 51177 meiotic sister chromatid cohesion 0.960474 7066 female meiosis sister chromatid cohesion 0.960474 48739 cardiac muscle fiber development 0.960470 19441 tryptophan catabolic process to kynurenine 0.960464 6463 steroid hormone receptor complex assembly 0.960452 46661 male sex differentiation 0.960452 10876 lipid localization 0.960432 19915 lipid storage 0.960432 5129 granulocyte macrophage colony-stimulating factor receptor binding 0.960404 1866 NK T cell proliferation 0.960307 1787 natural killer cell proliferation 0.960307 51095 regulation of helicase activity 0.960296 4098 cerebroside-sulfatase activity 0.960259 51597 response to methylmercury 0.960259 6646 phosphatidylethanolamine biosynthetic process 0.960257 6645 ethanolamine metabolic process 0.960257 6580 ethanolamine metabolic process 0.960257 46335 ethanolamine biosynthetic process 0.960257 19237 centromeric DNA binding 0.960241 46604 positive regulation of mitotic centrosome separation 0.960211 46602 regulation of mitotic centrosome separation 0.960211 31133 regulation of axon diameter 0.960209 32536 regulation of cell projection size 0.960209 6586 indolalkylamine metabolic process 0.960165 42434 indole derivative metabolic process 0.960165 42430 indole and derivative metabolic process 0.960165 43206 fibril organization 0.960164 45345 positive regulation of MHC class I biosynthetic process 0.960162 32003 interleukin-28 receptor binding 0.960162 42984 regulation of amyloid precursor protein biosynthetic process 0.960144 5953 CAAX-protein geranylgeranyltransferase complex 0.960114 9186 deoxyribonucleoside diphosphate metabolic process 0.960096 4042 acetyl-CoA:L-glutamate N-acetyltransferase activity 0.960066 3991 acetylglutamate kinase activity 0.960066 43142 single-stranded DNA-dependent ATPase activity 0.960062 46782 regulation of viral transcription 0.960039 60004 reflex 0.960032 50760 negative regulation of thymidylate synthase biosynthetic process 0.960017 50758 regulation of thymidylate synthase biosynthetic process 0.960017 42109 lymphotoxin A biosynthetic process 0.959943 40018 positive regulation of multicellular organism growth 0.959931 14895 smooth muscle hypertrophy 0.959921 31557 induction of programmed cell death in response to chemical stimulus 0.959873 48172 regulation of short-term neuronal synaptic plasticity 0.959873 45580 regulation of T cell differentiation 0.959867 42627 chylomicron 0.959851 15838 betaine transport 0.959840 15879 carnitine transport 0.959840 8803 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity 0.959824 8796 bis(5'-nucleosyl)-tetraphosphatase activity 0.959824 4081 bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity 0.959824 5121 Toll binding 0.959804 334 3-hydroxyanthranilate 3,4-dioxygenase activity 0.959776 32651 regulation of interleukin-1 beta production 0.959744 2697 regulation of immune effector process 0.959741 48312 intracellular distribution of mitochondria 0.959728 6851 mitochondrial calcium ion transport 0.959728 33342 negative regulation of collagen binding 0.959679 33341 regulation of collagen binding 0.959679 32234 regulation of calcium ion transport via store-operated calcium channel activity 0.959672 32929 negative regulation of superoxide release 0.959631 32928 regulation of superoxide release 0.959631 48012 hepatocyte growth factor receptor signaling pathway 0.959629 48025 negative regulation of nuclear mRNA splicing, via spliceosome 0.959605 16482 cytoplasmic transport 0.959605 48387 negative regulation of retinoic acid receptor signaling pathway 0.959601 51538 3 iron, 4 sulfur cluster binding 0.959583 8458 carnitine O-octanoyltransferase activity 0.959535 16414 O-octanoyltransferase activity 0.959535 6195 purine nucleotide catabolic process 0.959528 31580 membrane raft distribution 0.959498 1766 membrane raft polarization 0.959498 51665 membrane raft localization 0.959498 10906 regulation of glucose metabolic process 0.959487 1972 retinoic acid binding 0.959480 51023 regulation of immunoglobulin secretion 0.959460 43267 negative regulation of potassium ion transport 0.959450 50038 L-xylulose reductase (NADP+) activity 0.959438 5997 xylulose metabolic process 0.959438 35259 glucocorticoid receptor binding 0.959420 4320 oleoyl-[acyl-carrier-protein] hydrolase activity 0.959412 16297 acyl-[acyl-carrier-protein] hydrolase activity 0.959412 10281 acyl-[acyl-carrier-protein] hydrolase activity 0.959412 7253 cytoplasmic sequestering of NF-kappaB 0.959408 10883 regulation of lipid storage 0.959396 32902 nerve growth factor production 0.959390 32898 neurotrophin production 0.959390 70701 mucus layer 0.959341 70702 inner mucus layer 0.959341 70703 outer mucus layer 0.959341 33002 muscle cell proliferation 0.959323 9112 nucleobase metabolic process 0.959322 32652 regulation of interleukin-1 production 0.959319 5260 channel-conductance-controlling ATPase activity 0.959293 5224 ATP-binding and phosphorylation-dependent chloride channel activity 0.959293 19614 catechol catabolic process 0.959287 34313 diol catabolic process 0.959287 42424 catecholamine catabolic process 0.959287 32927 positive regulation of activin receptor signaling pathway 0.959273 14916 regulation of lung blood pressure 0.959245 1964 startle response 0.959227 45980 negative regulation of nucleotide metabolic process 0.959226 30526 granulocyte macrophage colony-stimulating factor receptor complex 0.959196 31232 extrinsic to external side of plasma membrane 0.959154 48677 axon extension involved in regeneration 0.959148 48682 sprouting of injured axon 0.959148 32717 negative regulation of interleukin-8 production 0.959146 8263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity 0.959100 9410 response to xenobiotic stimulus 0.959064 1655 urogenital system development 0.959058 31852 mu-type opioid receptor binding 0.959052 31628 opioid receptor binding 0.959052 9154 purine ribonucleotide catabolic process 0.959045 16742 hydroxymethyl-, formyl- and related transferase activity 0.959042 32769 negative regulation of monooxygenase activity 0.959038 217 DNA secondary structure binding 0.959030 60157 urinary bladder development 0.959025 32232 negative regulation of actin filament bundle formation 0.959009 51497 negative regulation of stress fiber formation 0.959009 15119 hexose phosphate transmembrane transporter activity 0.959003 15152 glucose-6-phosphate transmembrane transporter activity 0.959003 70555 response to interleukin-1 0.958990 33265 choline binding 0.958955 60037 pharyngeal system development 0.958947 51209 release of sequestered calcium ion into cytosol 0.958928 51283 negative regulation of sequestering of calcium ion 0.958928 51282 regulation of sequestering of calcium ion 0.958928 46874 quinolinate metabolic process 0.958908 4491 methylmalonate-semialdehyde dehydrogenase (acylating) activity 0.958907 18478 malonate-semialdehyde dehydrogenase (acetylating) activity 0.958907 48861 leukemia inhibitory factor signaling pathway 0.958903 48512 circadian behavior 0.958893 10259 multicellular organismal aging 0.958889 1910 regulation of leukocyte mediated cytotoxicity 0.958869 70740 tubulin-glutamic acid ligase activity 0.958858 18095 protein polyglutamylation 0.958858 48814 regulation of dendrite morphogenesis 0.958828 51966 regulation of synaptic transmission, glutamatergic 0.958826 30981 cortical microtubule cytoskeleton 0.958808 45822 negative regulation of heart contraction 0.958800 35127 post-embryonic limb morphogenesis 0.958784 35129 post-embryonic hindlimb morphogenesis 0.958784 35120 post-embryonic appendage morphogenesis 0.958784 70694 deoxyribonucleoside 5'-monophosphate N-glycosidase activity 0.958762 9159 deoxyribonucleoside monophosphate catabolic process 0.958762 43277 apoptotic cell clearance 0.958736 6526 arginine biosynthetic process 0.958732 14070 response to organic cyclic substance 0.958728 8617 guanosine metabolic process 0.958726 15014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process 0.958726 9826 unidimensional cell growth 0.958714 917 barrier septum formation 0.958714 42036 negative regulation of cytokine biosynthetic process 0.958709 20027 hemoglobin metabolic process 0.958675 1994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure 0.958665 1986 negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure 0.958665 42171 lysophosphatidic acid acyltransferase activity 0.958663 45905 positive regulation of translational termination 0.958661 45901 positive regulation of translational elongation 0.958661 6452 translational frameshifting 0.958661 45084 positive regulation of interleukin-12 biosynthetic process 0.958638 50927 positive regulation of positive chemotaxis 0.958631 50926 regulation of positive chemotaxis 0.958631 48793 pronephros development 0.958617 51011 microtubule minus-end binding 0.958617 51145 smooth muscle cell differentiation 0.958599 8215 spermine metabolic process 0.958581 32841 calcitonin binding 0.958569 60849 regulation of transcription involved in lymphatic endothelial cell fate commitment 0.958567 60850 regulation of transcription involved in cell fate commitment 0.958567 18197 peptidyl-aspartic acid modification 0.958520 42264 peptidyl-aspartic acid hydroxylation 0.958520 14037 Schwann cell differentiation 0.958518 48563 post-embryonic organ morphogenesis 0.958494 34447 very-low-density lipoprotein particle clearance 0.958494 4582 dolichyl-phosphate beta-D-mannosyltransferase activity 0.958490 32844 regulation of homeostatic process 0.958476 1543 ovarian follicle rupture 0.958470 45124 regulation of bone resorption 0.958445 46850 regulation of bone remodeling 0.958445 32497 detection of lipopolysaccharide 0.958436 30387 fructosamine-3-kinase activity 0.958424 30389 fructosamine metabolic process 0.958424 30393 fructoselysine metabolic process 0.958424 32350 regulation of hormone metabolic process 0.958415 32926 negative regulation of activin receptor signaling pathway 0.958398 46323 glucose import 0.958388 32024 positive regulation of insulin secretion 0.958386 9292 genetic transfer 0.958376 9294 DNA mediated transformation 0.958376 43415 positive regulation of skeletal muscle tissue regeneration 0.958372 43416 regulation of skeletal muscle tissue regeneration 0.958372 34764 positive regulation of transmembrane transport 0.958327 34767 positive regulation of ion transmembrane transport 0.958327 17116 single-stranded DNA-dependent ATP-dependent DNA helicase activity 0.958325 6266 DNA ligation 0.958322 6109 regulation of carbohydrate metabolic process 0.958315 50718 positive regulation of interleukin-1 beta secretion 0.958272 32731 positive regulation of interleukin-1 beta production 0.958272 50850 positive regulation of calcium-mediated signaling 0.958250 60541 respiratory system development 0.958229 7424 open tracheal system development 0.958229 31034 myosin filament assembly 0.958211 31033 myosin filament assembly or disassembly 0.958211 30241 muscle thick filament assembly 0.958211 15334 high affinity oligopeptide transporter activity 0.958182 42535 positive regulation of tumor necrosis factor biosynthetic process 0.958136 8785 alkyl hydroperoxide reductase activity 0.958134 45715 negative regulation of low-density lipoprotein receptor biosynthetic process 0.958098 4 biological_process 0.958079 7582 biological_process 0.958079 8306 associative learning 0.958072 4487 methylenetetrahydrofolate dehydrogenase (NAD+) activity 0.958060 15888 thiamin transport 0.958038 15234 thiamin transmembrane transporter activity 0.958038 42307 positive regulation of protein import into nucleus 0.958029 32101 regulation of response to external stimulus 0.958005 30803 negative regulation of cyclic nucleotide biosynthetic process 0.957991 30800 negative regulation of cyclic nucleotide metabolic process 0.957991 30809 negative regulation of nucleotide biosynthetic process 0.957991 3905 alkylbase DNA N-glycosylase activity 0.957989 8169 C-methyltransferase activity 0.957987 51293 establishment of spindle localization 0.957976 8126 acetylesterase activity 0.957941 1681 sialate O-acetylesterase activity 0.957941 34338 short-chain carboxylesterase activity 0.957941 50433 regulation of catecholamine secretion 0.957894 18352 protein-pyridoxal-5-phosphate linkage 0.957893 32732 positive regulation of interleukin-1 production 0.957876 6581 acetylcholine catabolic process 0.957867 1507 acetylcholine catabolic process in synaptic cleft 0.957867 43200 response to amino acid stimulus 0.957850 45545 syndecan binding 0.957844 5895 interleukin-5 receptor complex 0.957844 15802 basic amino acid transport 0.957836 50704 regulation of interleukin-1 secretion 0.957827 48186 inhibin beta-A binding 0.957794 34711 inhibin binding 0.957794 6531 aspartate metabolic process 0.957790 6533 aspartate catabolic process 0.957790 42363 fat-soluble vitamin catabolic process 0.957778 15252 hydrogen ion channel activity 0.957746 70095 fructose-6-phosphate binding 0.957722 4503 monophenol monooxygenase activity 0.957700 15333 peptide:hydrogen symporter activity 0.957649 22897 proton-dependent peptide secondary active transmembrane transporter activity 0.957649 43312 neutrophil degranulation 0.957633 60201 clathrin sculpted acetylcholine transport vesicle membrane 0.957615 50379 UDP-glucuronate 5'-epimerase activity 0.957555 16206 catechol O-methyltransferase activity 0.957528 9896 positive regulation of catabolic process 0.957497 6565 L-serine catabolic process 0.957486 824 inositol tetrakisphosphate 3-kinase activity 0.957458 43360 glial cell differentiation 0.957450 7404 glial cell differentiation 0.957450 9251 glucan catabolic process 0.957448 44247 cellular polysaccharide catabolic process 0.957448 30870 Mre11 complex 0.957440 14032 neural crest cell development 0.957439 50654 chondroitin sulfate proteoglycan metabolic process 0.957422 32235 negative regulation of calcium ion transport via store-operated calcium channel activity 0.957410 45840 positive regulation of mitosis 0.957366 51785 positive regulation of nuclear division 0.957366 5726 perichromatin fibrils 0.957362 70897 transcriptional preinitiation complex assembly 0.957311 51123 RNA polymerase II transcriptional preinitiation complex assembly 0.957311 10464 regulation of mesenchymal cell proliferation 0.957285 2053 positive regulation of mesenchymal cell proliferation 0.957285 19102 male somatic sex determination 0.957265 32233 positive regulation of actin filament bundle formation 0.957247 15785 UDP-galactose transport 0.957217 46631 alpha-beta T cell activation 0.957194 10640 regulation of platelet-derived growth factor receptor signaling pathway 0.957190 10641 positive regulation of platelet-derived growth factor receptor signaling pathway 0.957190 8469 histone-arginine N-methyltransferase activity 0.957190 70086 ubiquitin-dependent endocytosis 0.957168 7549 dosage compensation 0.957132 46653 tetrahydrofolate metabolic process 0.957126 9146 purine nucleoside triphosphate catabolic process 0.957126 32435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process 0.957102 50665 hydrogen peroxide biosynthetic process 0.957090 32846 positive regulation of homeostatic process 0.957077 70076 histone lysine demethylation 0.957070 33169 histone H3-K9 demethylation 0.957070 7406 negative regulation of neuroblast proliferation 0.957045 4514 nicotinate-nucleotide diphosphorylase (carboxylating) activity 0.957024 34213 quinolinate catabolic process 0.957024 31616 spindle pole centrosome 0.957003 7143 female meiosis 0.957003 43153 entrainment of circadian clock by photoperiod 0.956975 7182 common-partner SMAD protein phosphorylation 0.956971 60346 bone trabecula formation 0.956927 1955 blood vessel maturation 0.956927 93 mitotic telophase 0.956879 51326 telophase 0.956879 48742 regulation of skeletal muscle fiber development 0.956852 51492 regulation of stress fiber formation 0.956808 16540 protein autoprocessing 0.956803 9067 aspartate family amino acid biosynthetic process 0.956782 3878 ATP citrate synthase activity 0.956780 21571 rhombomere 5 development 0.956778 45778 positive regulation of ossification 0.956750 4733 pyridoxamine-phosphate oxidase activity 0.956734 43295 glutathione binding 0.956730 6670 sphingosine metabolic process 0.956708 6043 glucosamine catabolic process 0.956685 46348 amino sugar catabolic process 0.956685 9074 aromatic amino acid family catabolic process 0.956656 34474 U2 snRNA 3'-end processing 0.956637 34472 snRNA 3'-end processing 0.956637 4465 lipoprotein lipase activity 0.956617 8821 crossover junction endodeoxyribonuclease activity 0.956601 9596 detection of biotic stimulus 0.956579 6841 dicarboxylic acid transport 0.956571 60084 synaptic transmission involved in micturition 0.956553 48407 platelet-derived growth factor binding 0.956549 45634 regulation of melanocyte differentiation 0.956546 50932 regulation of pigment cell differentiation 0.956546 30887 positive regulation of myeloid dendritic cell activation 0.956541 46946 hydroxylysine metabolic process 0.956492 46947 hydroxylysine biosynthetic process 0.956492 32138 single base insertion or deletion binding 0.956462 2260 lymphocyte homeostasis 0.956444 50080 malonyl-CoA decarboxylase activity 0.956444 4492 methylmalonyl-CoA decarboxylase activity 0.956444 2077 acrosome matrix dispersal 0.956396 31329 regulation of cellular catabolic process 0.956379 50779 RNA destabilization 0.956347 289 nuclear-transcribed mRNA poly(A) tail shortening 0.956347 42473 outer ear morphogenesis 0.956345 2237 response to molecule of bacterial origin 0.956281 55008 cardiac muscle tissue morphogenesis 0.956276 60415 muscle tissue morphogenesis 0.956276 30942 endoplasmic reticulum signal peptide binding 0.956273 48558 embryonic gut morphogenesis 0.956201 19724 B cell mediated immunity 0.956200 30544 Hsp70 protein binding 0.956182 43278 response to morphine 0.956172 14072 response to isoquinoline alkaloid 0.956172 14067 negative regulation of phosphoinositide 3-kinase cascade 0.956154 8115 sarcosine oxidase activity 0.956106 50031 L-pipecolate oxidase activity 0.956106 30687 preribosome, large subunit precursor 0.956104 460 maturation of 5.8S rRNA 0.956104 466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 0.956104 70170 regulation of tooth mineralization 0.956080 4059 aralkylamine N-acetyltransferase activity 0.956058 50670 regulation of lymphocyte proliferation 0.956042 70663 regulation of leukocyte proliferation 0.956020 32944 regulation of mononuclear cell proliferation 0.956020 10886 positive regulation of cholesterol storage 0.956015 268 peroxisome targeting sequence binding 0.956007 739 DNA strand annealing activity 0.955991 5138 interleukin-6 receptor binding 0.955979 2052 positive regulation of neuroblast proliferation 0.955948 6741 NADP biosynthetic process 0.955913 46021 regulation of transcription from RNA polymerase II promoter, mitotic 0.955887 46022 positive regulation of transcription from RNA polymerase II promoter, mitotic 0.955887 45897 positive regulation of transcription, mitotic 0.955887 45896 regulation of transcription, mitotic 0.955887 16785 transferase activity, transferring selenium-containing groups 0.955865 16786 selenotransferase activity 0.955865 45078 positive regulation of interferon-gamma biosynthetic process 0.955843 32806 carboxy-terminal domain protein kinase complex 0.955838 42102 positive regulation of T cell proliferation 0.955829 34602 oxoglutarate dehydrogenase (NAD+) activity 0.955816 34601 oxoglutarate dehydrogenase [NAD(P)+] activity 0.955816 48634 regulation of muscle organ development 0.955776 32655 regulation of interleukin-12 production 0.955771 70530 K63-linked polyubiquitin binding 0.955768 46689 response to mercury ion 0.955750 55092 sterol homeostasis 0.955741 42632 cholesterol homeostasis 0.955741 8594 photoreceptor cell morphogenesis 0.955732 43583 ear development 0.955709 51897 positive regulation of protein kinase B signaling cascade 0.955687 47105 4-trimethylammoniobutyraldehyde dehydrogenase activity 0.955671 19145 aminobutyraldehyde dehydrogenase activity 0.955671 4001 adenosine kinase activity 0.955623 32872 regulation of stress-activated MAPK cascade 0.955615 32874 positive regulation of stress-activated MAPK cascade 0.955615 47936 glucose 1-dehydrogenase activity 0.955575 6494 protein amino acid terminal glycosylation 0.955549 6496 protein amino acid terminal N-glycosylation 0.955549 51241 negative regulation of multicellular organismal process 0.955548 33136 serine phosphorylation of STAT3 protein 0.955500 42501 serine phosphorylation of STAT protein 0.955500 2687 positive regulation of leukocyte migration 0.955495 6987 activation of signaling protein activity involved in unfolded protein response 0.955478 32075 positive regulation of nuclease activity 0.955478 16447 somatic recombination of immunoglobulin gene segments 0.955469 32675 regulation of interleukin-6 production 0.955432 50671 positive regulation of lymphocyte proliferation 0.955427 45240 dihydrolipoyl dehydrogenase complex 0.955411 5947 mitochondrial alpha-ketoglutarate dehydrogenase complex 0.955411 30062 mitochondrial tricarboxylic acid cycle enzyme complex 0.955411 70665 positive regulation of leukocyte proliferation 0.955392 32946 positive regulation of mononuclear cell proliferation 0.955392 19229 regulation of vasoconstriction 0.955367 9595 detection of biotic stimulus 0.955330 48678 response to axon injury 0.955323 21800 cerebral cortex tangential migration 0.955297 4312 fatty-acid synthase activity 0.955291 6603 phosphocreatine metabolic process 0.955285 46314 phosphocreatine biosynthetic process 0.955285 2762 negative regulation of myeloid leukocyte differentiation 0.955281 45918 negative regulation of cytolysis 0.955259 1952 regulation of cell-matrix adhesion 0.955194 42538 hyperosmotic salinity response 0.955189 6689 ganglioside catabolic process 0.955170 51973 positive regulation of telomerase activity 0.955152 32472 Golgi calcium ion transport 0.955140 32468 Golgi calcium ion homeostasis 0.955140 31347 regulation of defense response 0.955138 2040 sprouting angiogenesis 0.955122 43534 blood vessel endothelial cell migration 0.955100 4699 calcium-independent protein kinase C activity 0.955092 42345 regulation of NF-kappaB import into nucleus 0.955047 51608 histamine transport 0.954995 51615 histamine uptake 0.954995 15054 gastrin receptor activity 0.954947 70435 Shc-EGFR complex 0.954921 5018 platelet-derived growth factor alpha-receptor activity 0.954899 47323 [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity 0.954851 50614 delta24-sterol reductase activity 0.954802 51341 regulation of oxidoreductase activity 0.954781 16838 carbon-oxygen lyase activity, acting on phosphates 0.954776 16202 regulation of striated muscle tissue development 0.954756 16768 spermine synthase activity 0.954754 51569 regulation of histone H3-K4 methylation 0.954734 50716 positive regulation of interleukin-1 secretion 0.954710 32425 positive regulation of mismatch repair 0.954706 32423 regulation of mismatch repair 0.954706 42420 dopamine catabolic process 0.954685 51723 protein methylesterase activity 0.954657 51722 protein C-terminal methylesterase activity 0.954657 55010 ventricular cardiac muscle tissue morphogenesis 0.954632 34231 islet amyloid polypeptide processing 0.954609 34230 enkephalin processing 0.954609 10949 negative regulation of intestinal phytosterol absorption 0.954607 45796 negative regulation of intestinal cholesterol absorption 0.954607 60457 negative regulation of digestive system process 0.954607 45671 negative regulation of osteoclast differentiation 0.954602 1959 regulation of cytokine-mediated signaling pathway 0.954589 45780 positive regulation of bone resorption 0.954589 46852 positive regulation of bone remodeling 0.954589 7197 inhibition of adenylate cyclase activity by muscarinic acetylcholine receptor signaling pathway 0.954561 42537 benzene and derivative metabolic process 0.954530 5980 glycogen catabolic process 0.954513 15367 oxoglutarate:malate antiporter activity 0.954513 15140 malate transmembrane transporter activity 0.954513 30853 negative regulation of granulocyte differentiation 0.954510 6860 extracellular amino acid transport 0.954416 6858 extracellular transport 0.954416 8898 homocysteine S-methyltransferase activity 0.954395 50849 negative regulation of calcium-mediated signaling 0.954390 70232 regulation of T cell apoptosis 0.954373 70243 regulation of thymocyte apoptosis 0.954373 10524 positive regulation of calcium ion transport into cytosol 0.954327 48585 negative regulation of response to stimulus 0.954323 45088 regulation of innate immune response 0.954297 9394 2'-deoxyribonucleotide metabolic process 0.954292 6927 transformed cell apoptosis 0.954228 4595 pantetheine-phosphate adenylyltransferase activity 0.954223 4140 dephospho-CoA kinase activity 0.954223 70167 regulation of biomineral formation 0.954189 31702 type 1 angiotensin receptor binding 0.954154 31701 angiotensin receptor binding 0.954154 70664 negative regulation of leukocyte proliferation 0.954135 50672 negative regulation of lymphocyte proliferation 0.954135 32945 negative regulation of mononuclear cell proliferation 0.954135 2724 regulation of T cell cytokine production 0.954099 55001 muscle cell development 0.954099 15197 peptide transporter activity 0.954085 10561 negative regulation of glycoprotein biosynthetic process 0.954078 42985 negative regulation of amyloid precursor protein biosynthetic process 0.954078 30611 arsenate reductase activity 0.954052 32663 regulation of interleukin-2 production 0.954040 4729 oxygen-dependent protoporphyrinogen oxidase activity 0.954030 70818 protoporphyrinogen oxidase activity 0.954030 32733 positive regulation of interleukin-10 production 0.953970 30500 regulation of bone mineralization 0.953961 42347 negative regulation of NF-kappaB import into nucleus 0.953938 15909 long-chain fatty acid transport 0.953934 45603 positive regulation of endothelial cell differentiation 0.953933 33344 cholesterol efflux 0.953923 31943 regulation of glucocorticoid metabolic process 0.953896 43012 regulation of fusion of sperm to egg plasma membrane 0.953885 46888 negative regulation of hormone secretion 0.953877 46885 regulation of hormone biosynthetic process 0.953866 42396 phosphagen biosynthetic process 0.953864 32237 activation of store-operated calcium channel activity 0.953848 55075 potassium ion homeostasis 0.953818 2460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 0.953802 2250 adaptive immune response 0.953802 21987 cerebral cortex development 0.953801 46688 response to copper ion 0.953777 7097 nuclear migration 0.953762 48203 vesicle targeting, trans-Golgi to endosome 0.953740 9086 methionine biosynthetic process 0.953738 7042 lysosomal lumen acidification 0.953721 33989 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity 0.953692 46700 heterocycle catabolic process 0.953682 43114 regulation of vascular permeability 0.953649 16714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen 0.953648 50783 cocaine metabolic process 0.953643 46448 tropane alkaloid metabolic process 0.953643 18986 establishment of mitotic spindle localization 0.953640 30610 establishment of mitotic spindle localization 0.953640 30608 establishment of mitotic spindle localization 0.953640 30606 establishment of mitotic spindle localization 0.953640 30605 establishment of mitotic spindle localization 0.953640 51294 establishment of spindle orientation 0.953640 132 establishment of mitotic spindle orientation 0.953640 22010 myelination in the central nervous system 0.953623 32291 ensheathment of axons in the central nervous system 0.953623 4775 succinate-CoA ligase (ADP-forming) activity 0.953607 6597 spermine biosynthetic process 0.953593 16417 S-acyltransferase activity 0.953584 70830 tight junction assembly 0.953520 9051 pentose-phosphate shunt, oxidative branch 0.953520 19322 pentose biosynthetic process 0.953520 45837 negative regulation of membrane potential 0.953498 16652 oxidoreductase activity, acting on NADH or NADPH, NAD or NADP as acceptor 0.953496 8746 NAD(P) transhydrogenase activity 0.953496 1574 ganglioside biosynthetic process 0.953496 33044 regulation of chromosome organization 0.953491 6853 carnitine shuttle 0.953478 3333 amino acid transmembrane transport 0.953478 45768 positive regulation of anti-apoptosis 0.953414 10891 negative regulation of sequestering of triglyceride 0.953407 43243 positive regulation of protein complex disassembly 0.953381 33632 regulation of cell-cell adhesion mediated by integrin 0.953365 15227 acyl carnitine transporter activity 0.953354 46878 positive regulation of saliva secretion 0.953305 46877 regulation of saliva secretion 0.953305 19438 aromatic compound biosynthetic process 0.953290 51453 regulation of intracellular pH 0.953289 10224 response to UV-B 0.953283 6263 DNA-dependent DNA replication 0.953262 6262 DNA-dependent DNA replication 0.953262 6264 mitochondrial DNA replication 0.953262 70535 histone H2A K63-linked ubiquitination 0.953257 70534 protein K63-linked ubiquitination 0.953257 33299 secretion of lysosomal enzymes 0.953231 6144 purine base metabolic process 0.953221 4061 arylformamidase activity 0.953160 6601 creatine biosynthetic process 0.953110 5900 oncostatin-M receptor complex 0.953075 45085 negative regulation of interleukin-2 biosynthetic process 0.953069 42622 photoreceptor outer segment membrane 0.953037 5334 norephinephrine:sodium symporter activity 0.953016 5333 norepinephrine transmembrane transporter activity 0.953016 45740 positive regulation of DNA replication 0.952937 51902 negative regulation of mitochondrial depolarization 0.952917 46979 TAP2 binding 0.952914 46978 TAP1 binding 0.952914 46977 TAP binding 0.952914 43112 receptor metabolic process 0.952910 1782 B cell homeostasis 0.952892 42668 auditory receptor cell fate determination 0.952882 46588 negative regulation of calcium-dependent cell-cell adhesion 0.952774 46586 regulation of calcium-dependent cell-cell adhesion 0.952774 31400 negative regulation of protein modification process 0.952741 4504 peptidylglycine monooxygenase activity 0.952726 4598 peptidylamidoglycolate lyase activity 0.952726 43139 5'-3' DNA helicase activity 0.952707 46404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity 0.952705 51731 polynucleotide kinase activity 0.952705 51733 polydeoxyribonucleotide kinase activity 0.952705 51734 ATP-dependent polynucleotide kinase activity 0.952705 48867 stem cell fate determination 0.952699 15812 gamma-aminobutyric acid transport 0.952678 14051 gamma-aminobutyric acid secretion 0.952678 17046 peptide hormone binding 0.952668 7538 primary sex determination 0.952651 43471 regulation of cellular carbohydrate catabolic process 0.952648 43470 regulation of carbohydrate catabolic process 0.952648 45601 regulation of endothelial cell differentiation 0.952627 43383 negative T cell selection 0.952622 33057 reproductive behavior in a multicellular organism 0.952576 42993 positive regulation of transcription factor import into nucleus 0.952576 47042 3-alpha-hydroxysteroid dehydrogenase (B-specific) activity 0.952555 70286 axonemal dynein complex assembly 0.952533 60286 flagellar cell motility 0.952533 46755 non-lytic virus budding 0.952482 46753 non-lytic viral release 0.952482 19076 release of virus from host 0.952482 45731 protein secretion 0.952450 45166 protein secretion 0.952450 10288 response to lead ion 0.952448 50867 positive regulation of cell activation 0.952425 4014 adenosylmethionine decarboxylase activity 0.952388 45295 gamma-catenin binding 0.952386 5591 collagen type VIII 0.952340 5598 short-chain collagen 0.952340 9203 ribonucleoside triphosphate catabolic process 0.952316 9207 purine ribonucleoside triphosphate catabolic process 0.952316 920 cell separation during cytokinesis 0.952291 15860 purine nucleoside transport 0.952271 2204 somatic recombination of immunoglobulin genes during immune response 0.952241 2208 somatic diversification of immunoglobulins during immune response 0.952241 45190 isotype switching 0.952241 6296 nucleotide-excision repair, DNA incision, 5'-to lesion 0.952238 35019 somatic stem cell maintenance 0.952231 30388 fructose 1,6-bisphosphate metabolic process 0.952176 10638 positive regulation of organelle organization 0.952162 15761 mannose transport 0.952146 15578 mannose transmembrane transporter activity 0.952146 43516 regulation of DNA damage response, signal transduction by p53 class mediator 0.952120 55088 lipid homeostasis 0.952105 33857 diphosphoinositol-pentakisphosphate kinase activity 0.952096 826 inositol pyrophosphate synthase activity 0.952096 827 inositol 1,3,4,5,6-pentakisphosphate kinase activity 0.952096 828 inositol hexakisphosphate kinase activity 0.952096 832 inositol hexakisphosphate 5-kinase activity 0.952096 32236 positive regulation of calcium ion transport via store-operated calcium channel activity 0.952079 43259 laminin-10 complex 0.952077 6537 glutamate biosynthetic process 0.952041 2244 hemopoietic progenitor cell differentiation 0.952036 17055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly 0.952002 10744 positive regulation of macrophage derived foam cell differentiation 0.951970 4139 deoxyribose-phosphate aldolase activity 0.951953 70059 apoptosis in response to endoplasmic reticulum stress 0.951933 31933 telomeric heterochromatin 0.951905 5724 nuclear telomeric heterochromatin 0.951905 6868 glutamine transport 0.951830 15186 L-glutamine transmembrane transporter activity 0.951830 70251 pristanate-CoA ligase activity 0.951808 50197 phytanate-CoA ligase activity 0.951808 6556 S-adenosylmethionine biosynthetic process 0.951806 34214 protein hexamerization 0.951782 50480 imidazolonepropionase activity 0.951760 19556 histidine catabolic process to glutamate and formamide 0.951760 50347 trans-octaprenyltranstransferase activity 0.951712 48710 regulation of astrocyte differentiation 0.951693 45672 positive regulation of osteoclast differentiation 0.951664 6570 tyrosine metabolic process 0.951591 21885 forebrain cell migration 0.951541 32089 NACHT domain binding 0.951540 32496 response to lipopolysaccharide 0.951533 21795 cerebral cortex cell migration 0.951505 2683 negative regulation of immune system process 0.951482 15870 acetylcholine transport 0.951470 5277 acetylcholine transmembrane transporter activity 0.951470 51024 positive regulation of immunoglobulin secretion 0.951364 32088 negative regulation of NF-kappaB transcription factor activity 0.951342 31265 CD95 death-inducing signaling complex 0.951326 45687 positive regulation of glial cell differentiation 0.951322 14015 positive regulation of gliogenesis 0.951322 46931 pore complex assembly 0.951305 8612 peptidyl-lysine modification to hypusine 0.951297 46516 hypusine metabolic process 0.951297 2715 regulation of natural killer cell mediated immunity 0.951284 45845 regulation of natural killer cell mediated immunity 0.951284 42269 regulation of natural killer cell mediated cytotoxicity 0.951284 45602 negative regulation of endothelial cell differentiation 0.951277 42088 T-helper 1 type immune response 0.951263 1878 response to yeast 0.951229 1872 zymosan binding 0.951229 16872 intramolecular lyase activity 0.951181 4512 inositol-3-phosphate synthase activity 0.951181 738 DNA catabolic process, exonucleolytic 0.951169 48384 retinoic acid receptor signaling pathway 0.951153 42517 positive regulation of tyrosine phosphorylation of Stat3 protein 0.951144 2696 positive regulation of leukocyte activation 0.951139 48547 gut morphogenesis 0.951113 50543 icosatetraenoic acid binding 0.951077 50542 icosanoid binding 0.951077 45880 positive regulation of smoothened signaling pathway 0.951053 16256 N-glycan processing to lysosome 0.951036 6492 N-glycan processing 0.951036 32914 positive regulation of transforming growth factor-beta1 production 0.951033 7079 mitotic chromosome movement towards spindle pole 0.951033 45346 regulation of MHC class II biosynthetic process 0.951013 60001 minus-end directed microfilament motor activity 0.950987 42834 peptidoglycan binding 0.950979 1933 negative regulation of protein amino acid phosphorylation 0.950976 2326 B cell lineage commitment 0.950944 43293 apoptosome 0.950939 43260 laminin-11 complex 0.950918 7625 grooming behavior 0.950903 14059 regulation of dopamine secretion 0.950898 48850 hypophysis morphogenesis 0.950891 60126 somatotropin secreting cell differentiation 0.950891 21707 cerebellar granule cell differentiation 0.950886 48267 response to pain 0.950872 48266 behavioral response to pain 0.950872 17081 chloride channel regulator activity 0.950843 3863 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity 0.950816 16440 chromatin silencing 0.950807 17065 single-strand selective uracil DNA N-glycosylase activity 0.950794 16048 detection of temperature stimulus 0.950727 45163 clustering of voltage-gated potassium channels 0.950698 43648 dicarboxylic acid metabolic process 0.950687 17002 activin receptor activity 0.950678 729 DNA double-strand break processing 0.950654 45239 tricarboxylic acid cycle enzyme complex 0.950630 35064 methylated histone residue binding 0.950623 2378 immunoglobulin biosynthetic process 0.950599 46521 sphingoid catabolic process 0.950592 30957 Tat protein binding 0.950575 16832 aldehyde-lyase activity 0.950563 16228 aldehyde-lyase activity 0.950563 51010 microtubule plus-end binding 0.950558 8808 cardiolipin synthase activity 0.950553 30572 phosphatidyltransferase activity 0.950553 45471 response to ethanol 0.950481 5229 intracellular calcium activated chloride channel activity 0.950478 70327 thyroid hormone transport 0.950456 70324 thyroid hormone binding 0.950456 8216 spermidine metabolic process 0.950437 33878 hormone-sensitive lipase activity 0.950408 10827 regulation of glucose transport 0.950387 40001 establishment of mitotic spindle localization 0.950373 21781 glial cell fate commitment 0.950333 48524 positive regulation of viral reproduction 0.950331 14823 response to activity 0.950273 5025 transforming growth factor beta receptor activity, type I 0.950267 8117 sphinganine-1-phosphate aldolase activity 0.950263 9122 deoxyribonucleotide metabolic process 0.950239 9262 deoxyribonucleotide metabolic process 0.950239 9393 deoxyribonucleotide metabolic process 0.950239 43545 molybdopterin cofactor metabolic process 0.950214 6777 Mo-molybdopterin cofactor biosynthetic process 0.950214 32324 molybdopterin cofactor biosynthetic process 0.950214 51189 prosthetic group metabolic process 0.950214 19720 Mo-molybdopterin cofactor metabolic process 0.950214 4155 6,7-dihydropteridine reductase activity 0.950167 51066 dihydrobiopterin metabolic process 0.950167 96 sulfur amino acid metabolic process 0.950157 33081 regulation of T cell differentiation in the thymus 0.950153 50855 regulation of B cell receptor signaling pathway 0.950118 50861 positive regulation of B cell receptor signaling pathway 0.950118 6285 base-excision repair, AP site formation 0.950114 7199 G-protein signaling, coupled to cGMP nucleotide second messenger 0.950111 4332 fructose-bisphosphate aldolase activity 0.950097 48256 flap endonuclease activity 0.950090 18344 protein geranylgeranylation 0.950087 16748 succinyltransferase activity 0.950065 51155 positive regulation of striated muscle cell differentiation 0.950019 14047 glutamate secretion 0.950014 42311 vasodilation 0.950014 46146 tetrahydrobiopterin metabolic process 0.949938 16003 carbon-nitrogen ligase activity, with glutamine as amido-N-donor 0.949929 16362 activin receptor activity, type II 0.949925 30815 negative regulation of cAMP metabolic process 0.949882 30818 negative regulation of cAMP biosynthetic process 0.949882 48617 embryonic foregut morphogenesis 0.949877 35054 embryonic heart tube anterior/posterior pattern formation 0.949877 32757 positive regulation of interleukin-8 production 0.949856 1607 neuromedin U receptor activity 0.949802 42924 neuromedin U binding 0.949802 42417 dopamine metabolic process 0.949782 32155 cell division site part 0.949745 70537 histone H2A K63-linked deubiquitination 0.949730 6047 UDP-N-acetylglucosamine metabolic process 0.949725 33683 nucleotide-excision repair, DNA incision 0.949696 18107 peptidyl-threonine phosphorylation 0.949661 47757 chondroitin-glucuronate 5-epimerase activity 0.949635 6739 NADP metabolic process 0.949633 70733 protein adenylyltransferase activity 0.949587 31177 phosphopantetheine binding 0.949566 43203 axon hillock 0.949491 51881 regulation of mitochondrial membrane potential 0.949483 16189 synaptic vesicle to endosome fusion 0.949442 5969 serine-pyruvate aminotransferase complex 0.949442 50766 positive regulation of phagocytosis 0.949440 48156 tau protein binding 0.949435 4505 phenylalanine 4-monooxygenase activity 0.949421 42346 positive regulation of NF-kappaB import into nucleus 0.949400 10248 establishment or maintenance of transmembrane electrochemical gradient 0.949367 21513 spinal cord dorsal/ventral patterning 0.949350 47012 sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity 0.949346 252 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity 0.949346 8396 oxysterol 7-alpha-hydroxylase activity 0.949343 15168 glycerol transmembrane transporter activity 0.949343 15254 glycerol channel activity 0.949343 32203 telomere formation via telomerase 0.949341 55003 cardiac myofibril assembly 0.949333 51482 elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) 0.949303 5914 spot adherens junction 0.949297 15805 S-adenosylmethionine transport 0.949249 95 S-adenosylmethionine transmembrane transporter activity 0.949249 34653 retinoic acid catabolic process 0.949228 48565 gut development 0.949211 5362 low-affinity glucose:sodium symporter activity 0.949201 15908 fatty acid transport 0.949195 43014 alpha-tubulin binding 0.949166 31016 pancreas development 0.949152 51635 bacterial cell surface binding 0.949148 16619 malate dehydrogenase (oxaloacetate-decarboxylating) activity 0.949104 4471 malate dehydrogenase (decarboxylating) activity 0.949104 6558 L-phenylalanine metabolic process 0.949044 6559 L-phenylalanine catabolic process 0.949044 34970 histone H3-R2 methylation 0.948981 16594 glycine binding 0.948976 31574 S-M checkpoint 0.948959 19781 NEDD8 activating enzyme activity 0.948959 8198 ferrous iron binding 0.948940 10884 positive regulation of lipid storage 0.948912 33699 DNA 5'-adenosine monophosphate hydrolase activity 0.948911 9110 vitamin biosynthetic process 0.948887 50113 inositol oxygenase activity 0.948863 19310 inositol catabolic process 0.948863 42587 glycogen granule 0.948860 9072 aromatic amino acid family metabolic process 0.948826 16064 immunoglobulin mediated immune response 0.948805 1618 viral receptor activity 0.948764 32767 copper-dependent protein binding 0.948715 15165 pyrimidine nucleotide sugar transmembrane transporter activity 0.948673 5339 nucleotide-sugar transmembrane transporter activity 0.948673 4044 amidophosphoribosyltransferase activity 0.948621 43270 positive regulation of ion transport 0.948598 15111 iodide transmembrane transporter activity 0.948595 32055 negative regulation of translation in response to stress 0.948578 32057 negative regulation of translational initiation in response to stress 0.948578 70287 ferritin receptor activity 0.948573 34056 estrogen response element binding 0.948525 46324 regulation of glucose import 0.948490 48709 oligodendrocyte differentiation 0.948476 1556 oocyte maturation 0.948456 15810 aspartate transport 0.948440 8303 caspase complex 0.948380 45070 positive regulation of viral genome replication 0.948372 46632 alpha-beta T cell differentiation 0.948360 42640 anagen 0.948351 48752 semicircular canal morphogenesis 0.948332 60005 vestibular reflex 0.948332 15918 sterol transport 0.948302 30301 cholesterol transport 0.948302 281 cytokinesis after mitosis 0.948264 42776 mitochondrial ATP synthesis coupled proton transport 0.948257 10025 wax biosynthetic process 0.948187 10166 wax metabolic process 0.948187 31665 negative regulation of lipopolysaccharide-mediated signaling pathway 0.948184 31664 regulation of lipopolysaccharide-mediated signaling pathway 0.948184 14912 negative regulation of smooth muscle cell migration 0.948182 10594 regulation of endothelial cell migration 0.948132 15844 monoamine transport 0.948113 15793 glycerol transport 0.948112 22816 sodium ion transmembrane transporter activity 0.948112 30185 nitric oxide transport 0.948088 30641 regulation of cellular pH 0.948086 14031 mesenchymal cell development 0.948076 5174 CD40 receptor binding 0.948042 15181 arginine transmembrane transporter activity 0.948039 45787 positive regulation of cell cycle 0.948006 21511 spinal cord patterning 0.947994 70273 phosphatidylinositol-4-phosphate binding 0.947945 60628 regulation of ER to Golgi vesicle-mediated transport 0.947897 51535 syntaxin-5 binding 0.947897 8588 release of cytoplasmic sequestered NF-kappaB 0.947877 42643 actomyosin, actin part 0.947849 51451 myoblast migration 0.947800 21983 pituitary gland development 0.947778 51147 regulation of muscle cell differentiation 0.947747 3698 single-stranded DNA binding 0.947683 3699 single-stranded DNA binding 0.947683 31618 nuclear centromeric heterochromatin 0.947677 43265 ectoplasm 0.947656 51925 regulation of calcium ion transport via voltage-gated calcium channel activity 0.947640 43467 regulation of generation of precursor metabolites and energy 0.947639 45112 integrin biosynthetic process 0.947607 42392 sphingosine-1-phosphate phosphatase activity 0.947559 19532 oxalate transport 0.947556 19531 oxalate transmembrane transporter activity 0.947556 21965 spinal cord ventral commissure morphogenesis 0.947532 7412 axon target recognition 0.947522 2113 interleukin-33 binding 0.947511 2114 interleukin-33 receptor activity 0.947511 33262 regulation of DNA replication during S phase 0.947462 9886 post-embryonic morphogenesis 0.947420 4397 histidine ammonia-lyase activity 0.947414 15198 oligopeptide transporter activity 0.947409 48703 embryonic viscerocranium morphogenesis 0.947382 33962 cytoplasmic mRNA processing body assembly 0.947366 34063 stress granule assembly 0.947366 30147 natriuresis 0.947346 30146 diuresis 0.947346 5642 annulate lamellae 0.947339 31571 G1/S DNA damage checkpoint 0.947274 18894 dibenzo-p-dioxin metabolic process 0.947269 15712 hexose phosphate transport 0.947264 15760 glucose-6-phosphate transport 0.947264 50816 phosphothreonine binding 0.947243 32036 myosin heavy chain binding 0.947220 43539 protein serine/threonine kinase activator activity 0.947200 1817 regulation of cytokine production 0.947178 6781 succinyl-CoA pathway 0.947173 9125 nucleoside monophosphate catabolic process 0.947112 70643 vitamin D 25-hydroxylase activity 0.947098 30343 vitamin D3 25-hydroxylase activity 0.947098 43288 apocarotenoid metabolic process 0.947093 42574 retinal metabolic process 0.947093 30219 megakaryocyte differentiation 0.947087 48840 otolith development 0.947076 6110 regulation of glycolysis 0.947036 2566 somatic diversification of immune receptors via somatic mutation 0.947023 16446 somatic hypermutation of immunoglobulin genes 0.947023 42559 pteridine and derivative biosynthetic process 0.947016 2026 regulation of the force of heart contraction 0.947012 4744 retinal isomerase activity 0.946980 50708 regulation of protein secretion 0.946955 2063 chondrocyte development 0.946942 32790 ribosome disassembly 0.946931 32988 ribonucleoprotein complex disassembly 0.946931 5128 erythropoietin receptor binding 0.946883 6910 phagocytosis, recognition 0.946853 19721 pteridine and derivative metabolic process 0.946845 42558 pteridine and derivative metabolic process 0.946845 51496 positive regulation of stress fiber formation 0.946827 48339 paraxial mesoderm development 0.946786 70233 negative regulation of T cell apoptosis 0.946781 70244 negative regulation of thymocyte apoptosis 0.946781 45900 negative regulation of translational elongation 0.946760 46514 ceramide catabolic process 0.946742 6348 chromatin silencing at telomere 0.946736 9065 glutamine family amino acid catabolic process 0.946727 32400 melanosome localization 0.946711 51875 pigment granule localization 0.946711 7260 tyrosine phosphorylation of STAT protein 0.946709 51251 positive regulation of lymphocyte activation 0.946647 43603 cellular amide metabolic process 0.946571 43080 female germ cell nucleus 0.946545 42585 germinal vesicle 0.946545 51005 negative regulation of lipoprotein lipase activity 0.946477 19372 lipoxygenase pathway 0.946448 43576 regulation of respiratory gaseous exchange 0.946409 2562 somatic diversification of immune receptors via germline recombination within a single locus 0.946383 16444 somatic cell DNA recombination 0.946383 43030 regulation of macrophage activation 0.946372 16642 oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor 0.946352 4375 glycine dehydrogenase (decarboxylating) activity 0.946352 2281 macrophage activation during immune response 0.946349 2275 myeloid cell activation during immune response 0.946349 30949 positive regulation of vascular endothelial growth factor receptor signaling pathway 0.946309 16784 3-mercaptopyruvate sulfurtransferase activity 0.946304 51096 positive regulation of helicase activity 0.946284 51323 metaphase 0.946284 3947 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity 0.946255 45933 positive regulation of muscle contraction 0.946237 32780 negative regulation of ATPase activity 0.946218 22004 midbrain-hindbrain boundary maturation during brain development 0.946207 5026 transforming growth factor beta receptor activity, type II 0.946170 48259 regulation of receptor-mediated endocytosis 0.946138 31112 positive regulation of microtubule polymerization or depolymerization 0.946086 46605 regulation of centrosome cycle 0.946073 50965 detection of temperature stimulus involved in sensory perception of pain 0.946057 50961 detection of temperature stimulus involved in sensory perception 0.946057 50870 positive regulation of T cell activation 0.946028 4960 thromboxane receptor activity 0.946014 4961 thromboxane A2 receptor activity 0.946014 30366 Mo-molybdopterin synthase activity 0.945966 5901 caveola 0.945935 9066 aspartate family amino acid metabolic process 0.945893 46965 retinoid X receptor binding 0.945881 48936 peripheral nervous system neuron axonogenesis 0.945869 14889 muscle atrophy 0.945869 1640 adenylate cyclase inhibiting metabotropic glutamate receptor activity 0.945866 45178 basal part of cell 0.945848 21782 glial cell development 0.945823 21572 rhombomere 6 development 0.945772 45517 interleukin-20 receptor binding 0.945724 60231 mesenchymal to epithelial transition 0.945721 3382 epithelial cell morphogenesis 0.945721 19 regulation of mitotic recombination 0.945703 42116 macrophage activation 0.945688 48050 post-embryonic eye morphogenesis 0.945676 48539 bone marrow development 0.945673 31960 response to corticosteroid stimulus 0.945615 9070 serine family amino acid biosynthetic process 0.945614 32401 establishment of melanosome localization 0.945603 51650 establishment of vesicle localization 0.945603 51905 establishment of pigment granule localization 0.945603 48730 epidermis morphogenesis 0.945588 30595 leukocyte chemotaxis 0.945554 45732 positive regulation of protein catabolic process 0.945545 2042 cell migration involved in sprouting angiogenesis 0.945535 60326 cell chemotaxis 0.945509 51928 positive regulation of calcium ion transport 0.945478 3886 DNA (cytosine-5-)-methyltransferase activity 0.945463 45650 negative regulation of macrophage differentiation 0.945414 32997 Fc receptor complex 0.945383 32998 Fc-epsilon receptor I complex 0.945383 2443 leukocyte mediated immunity 0.945379 42087 leukocyte mediated immunity 0.945379 19723 leukocyte mediated immunity 0.945379 18343 protein farnesylation 0.945365 60081 membrane hyperpolarization 0.945337 9134 nucleoside diphosphate catabolic process 0.945330 30217 T cell differentiation 0.945317 2076 osteoblast development 0.945317 43589 skin morphogenesis 0.945316 50544 arachidonic acid binding 0.945300 6528 asparagine metabolic process 0.945284 3978 UDP-glucose 4-epimerase activity 0.945241 19388 galactose catabolic process 0.945241 2726 positive regulation of T cell cytokine production 0.945240 60393 regulation of pathway-restricted SMAD protein phosphorylation 0.945222 7210 serotonin receptor signaling pathway 0.945220 50731 positive regulation of peptidyl-tyrosine phosphorylation 0.945197 30047 actin modification 0.945193 9586 rhodopsin mediated phototransduction 0.945190 19371 cyclooxygenase pathway 0.945096 46033 AMP metabolic process 0.945064 5600 collagen type XIII 0.945048 30936 transmembrane collagen 0.945048 6101 citrate metabolic process 0.945027 33613 transcription activator binding 0.944999 60042 retina morphogenesis in camera-type eye 0.944997 70498 interleukin-1-mediated signaling pathway 0.944992 34762 regulation of transmembrane transport 0.944990 33151 V(D)J recombination 0.944984 50691 regulation of defense response to virus by host 0.944979 42364 water-soluble vitamin biosynthetic process 0.944926 19321 pentose metabolic process 0.944908 30836 positive regulation of actin filament depolymerization 0.944898 16721 oxidoreductase activity, acting on superoxide radicals as acceptor 0.944882 4784 superoxide dismutase activity 0.944882 90068 positive regulation of cell cycle process 0.944881 45408 regulation of interleukin-6 biosynthetic process 0.944872 43546 molybdopterin cofactor binding 0.944855 8482 sulfite oxidase activity 0.944855 19359 nicotinamide nucleotide biosynthetic process 0.944841 48875 chemical homeostasis within a tissue 0.944835 43129 surfactant homeostasis 0.944835 10389 regulation of G2/M transition of mitotic cell cycle 0.944833 16725 oxidoreductase activity, acting on CH or CH2 groups 0.944798 48853 forebrain morphogenesis 0.944780 50866 negative regulation of cell activation 0.944748 70034 telomeric RNA binding 0.944683 46883 regulation of hormone secretion 0.944640 46642 negative regulation of alpha-beta T cell proliferation 0.944613 32330 regulation of chondrocyte differentiation 0.944587 15728 mevalonate transport 0.944565 15130 mevalonate transmembrane transporter activity 0.944565 51054 positive regulation of DNA metabolic process 0.944545 50178 phenylpyruvate tautomerase activity 0.944517 48260 positive regulation of receptor-mediated endocytosis 0.944506 15780 nucleotide-sugar transport 0.944487 30911 TPR domain binding 0.944463 35094 response to nicotine 0.944442 6657 CDP-choline pathway 0.944372 32148 activation of protein kinase B activity 0.944371 22898 regulation of transmembrane transporter activity 0.944340 45590 negative regulation of regulatory T cell differentiation 0.944324 45075 regulation of interleukin-12 biosynthetic process 0.944314 50865 regulation of cell activation 0.944298 30332 cyclin binding 0.944267 51384 response to glucocorticoid stimulus 0.944243 32972 regulation of muscle filament sliding speed 0.944227 42531 positive regulation of tyrosine phosphorylation of STAT protein 0.944217 10670 positive regulation of oxygen and reactive oxygen species metabolic process 0.944200 15187 glycine transmembrane transporter activity 0.944139 8442 3-hydroxyisobutyrate dehydrogenase activity 0.944131 51491 positive regulation of filopodium assembly 0.944050 51489 regulation of filopodium assembly 0.944050 35026 leading edge cell differentiation 0.944034 6843 mitochondrial citrate transport 0.943986 80025 phosphatidylinositol-3,5-bisphosphate binding 0.943959 10314 phosphatidylinositol-5-phosphate binding 0.943959 1504 neurotransmitter uptake 0.943900 48222 glycoprotein network 0.943889 44426 cell wall part 0.943889 15365 dicarboxylic acid transmembrane transporter activity 0.943868 5312 dicarboxylic acid transmembrane transporter activity 0.943868 30879 mammary gland development 0.943855 31115 negative regulation of microtubule polymerization 0.943841 30004 cellular monovalent inorganic cation homeostasis 0.943836 42516 regulation of tyrosine phosphorylation of Stat3 protein 0.943823 8632 apoptosis 0.943796 43540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 complex 0.943793 43567 regulation of insulin-like growth factor receptor signaling pathway 0.943792 31113 regulation of microtubule polymerization 0.943774 21797 forebrain anterior/posterior pattern formation 0.943766 21536 diencephalon development 0.943766 17153 sodium:dicarboxylate symporter activity 0.943761 214 tRNA-intron endonuclease complex 0.943755 31379 RNA-directed RNA polymerase complex 0.943744 31380 nuclear RNA-directed RNA polymerase complex 0.943744 6375 nuclear mRNA splicing, via spliceosome 0.943742 6374 nuclear mRNA splicing, via spliceosome 0.943742 380 alternative nuclear mRNA splicing, via spliceosome 0.943742 784 nuclear chromosome, telomeric region 0.943734 31116 positive regulation of microtubule polymerization 0.943721 10159 specification of organ position 0.943696 33363 secretory granule organization 0.943689 1919 regulation of receptor recycling 0.943666 31643 positive regulation of myelination 0.943621 45649 regulation of macrophage differentiation 0.943611 6948 induction by virus of host cell-cell fusion 0.943599 42401 cellular biogenic amine biosynthetic process 0.943598 6200 ATP catabolic process 0.943590 9435 NAD biosynthetic process 0.943567 6527 arginine catabolic process 0.943562 9143 nucleoside triphosphate catabolic process 0.943526 2791 regulation of peptide secretion 0.943508 90087 regulation of peptide transport 0.943508 4329 formate-tetrahydrofolate ligase activity 0.943476 2507 tolerance induction 0.943465 40017 positive regulation of locomotion 0.943463 31490 chromatin DNA binding 0.943438 15791 polyol transport 0.943434 14707 branchiomeric skeletal muscle development 0.943406 30205 dermatan sulfate metabolic process 0.943404 30208 dermatan sulfate biosynthetic process 0.943404 172 ribonuclease MRP complex 0.943404 5889 hydrogen:potassium-exchanging ATPase complex 0.943379 50 urea cycle 0.943353 19627 urea metabolic process 0.943353 51208 sequestering of calcium ion 0.943320 34211 GTP-dependent protein kinase activity 0.943310 32473 external side of mitochondrial outer membrane 0.943310 16441 posttranscriptional gene silencing 0.943307 16246 RNA interference 0.943307 35194 posttranscriptional gene silencing by RNA 0.943307 45405 regulation of interleukin-5 biosynthetic process 0.943261 45407 positive regulation of interleukin-5 biosynthetic process 0.943261 32703 negative regulation of interleukin-2 production 0.943259 9820 alkaloid metabolic process 0.943251 30186 melatonin metabolic process 0.943240 30187 melatonin biosynthetic process 0.943240 5151 interleukin-1, Type II receptor binding 0.943213 10824 regulation of centrosome duplication 0.943202 6346 methylation-dependent chromatin silencing 0.943143 6760 folic acid and derivative metabolic process 0.943142 4485 methylcrotonoyl-CoA carboxylase activity 0.943138 6552 leucine catabolic process 0.943138 6020 inositol metabolic process 0.943131 16913 follicle-stimulating hormone activity 0.943117 16843 amine-lyase activity 0.943068 16844 strictosidine synthase activity 0.943068 19276 UDP-N-acetylgalactosamine metabolic process 0.943063 16034 maleylacetoacetate isomerase activity 0.943020 6729 tetrahydrobiopterin biosynthetic process 0.942982 31669 cellular response to nutrient levels 0.942973 45578 negative regulation of B cell differentiation 0.942966 35308 negative regulation of protein amino acid dephosphorylation 0.942934 35305 negative regulation of dephosphorylation 0.942934 47787 delta4-3-oxosteroid 5beta-reductase activity 0.942923 70739 protein-glutamic acid ligase activity 0.942921 5536 glucose binding 0.942879 48569 post-embryonic organ development 0.942875 35166 post-embryonic hemopoiesis 0.942875 6769 nicotinamide metabolic process 0.942849 46496 nicotinamide nucleotide metabolic process 0.942849 10562 positive regulation of phosphorus metabolic process 0.942835 45937 positive regulation of phosphate metabolic process 0.942835 31854 orexigenic neuropeptide QRFP receptor binding 0.942827 60259 regulation of feeding behavior 0.942827 48711 positive regulation of astrocyte differentiation 0.942824 46848 hydroxyapatite binding 0.942821 51046 regulation of secretion 0.942792 45175 basal protein localization 0.942779 15697 quaternary ammonium group transport 0.942760 45661 regulation of myoblast differentiation 0.942759 7512 adult heart development 0.942755 7511 heart development 0.942755 9264 deoxyribonucleotide catabolic process 0.942716 50434 positive regulation of viral transcription 0.942676 22027 interkinetic nuclear migration 0.942655 51647 nucleus localization 0.942655 30953 spindle astral microtubule organization 0.942655 2763 positive regulation of myeloid leukocyte differentiation 0.942520 10155 regulation of proton transport 0.942491 34765 regulation of ion transmembrane transport 0.942488 40036 regulation of fibroblast growth factor receptor signaling pathway 0.942487 46541 saliva secretion 0.942468 31987 locomotion involved in locomotory behavior 0.942440 47150 betaine-homocysteine S-methyltransferase activity 0.942414 30505 inorganic diphosphate transport 0.942389 48048 embryonic eye morphogenesis 0.942365 16942 insulin-like growth factor binding protein complex 0.942348 6104 succinyl-CoA metabolic process 0.942338 42289 MHC class II protein binding 0.942322 6641 triglyceride metabolic process 0.942267 5586 collagen type III 0.942247 43113 receptor clustering 0.942217 47865 dimethylglycine dehydrogenase activity 0.942199 46219 indolalkylamine biosynthetic process 0.942149 42435 indole derivative biosynthetic process 0.942149 2031 G-protein coupled receptor internalization 0.942148 16716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen 0.942129 70938 contractile ring 0.942129 48845 venous blood vessel morphogenesis 0.942129 5826 actomyosin contractile ring 0.942129 50868 negative regulation of T cell activation 0.942125 1917 photoreceptor inner segment 0.942070 30263 apoptotic chromosome condensation 0.942000 51445 regulation of meiotic cell cycle 0.941992 15322 secondary active oligopeptide transmembrane transporter activity 0.941979 5427 proton-dependent oligopeptide secondary active transmembrane transporter activity 0.941979 21785 branchiomotor neuron axon guidance 0.941958 42327 positive regulation of phosphorylation 0.941947 51100 negative regulation of binding 0.941939 16045 detection of bacterium 0.941914 48273 mitogen-activated protein kinase p38 binding 0.941909 4711 ribosomal protein S6 kinase activity 0.941909 45616 regulation of keratinocyte differentiation 0.941908 4148 dihydrolipoyl dehydrogenase activity 0.941813 32971 regulation of muscle filament sliding 0.941775 31531 thyrotropin-releasing hormone receptor binding 0.941764 51428 peptide hormone receptor binding 0.941764 50509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity 0.941762 42328 heparan sulfate N-acetylglucosaminyltransferase activity 0.941762 45058 T cell selection 0.941738 4351 glutamate decarboxylase activity 0.941713 6540 glutamate decarboxylation to succinate 0.941713 30852 regulation of granulocyte differentiation 0.941694 32412 regulation of ion transmembrane transporter activity 0.941690 1961 positive regulation of cytokine-mediated signaling pathway 0.941678 16361 activin receptor activity, type I 0.941671 50652 dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process 0.941668 43523 regulation of neuron apoptosis 0.941659 51452 intracellular pH reduction 0.941656 43393 regulation of protein binding 0.941652 4774 succinate-CoA ligase activity 0.941647 32743 positive regulation of interleukin-2 production 0.941638 45651 positive regulation of macrophage differentiation 0.941635 32069 regulation of nuclease activity 0.941617 9895 negative regulation of catabolic process 0.941613 2694 regulation of leukocyte activation 0.941606 2761 regulation of myeloid leukocyte differentiation 0.941601 44154 histone H3-K14 acetylation 0.941571 6295 nucleotide-excision repair, DNA incision, 3'-to lesion 0.941566 42582 azurophil granule 0.941563 5766 primary lysosome 0.941563 6767 water-soluble vitamin metabolic process 0.941510 30292 protein tyrosine kinase inhibitor activity 0.941496 15845 quaternary ammonium group transport 0.941493 33577 protein amino acid glycosylation in endoplasmic reticulum 0.941475 9219 pyrimidine deoxyribonucleotide metabolic process 0.941469 9008 DNA-methyltransferase activity 0.941454 16553 base conversion or substitution editing 0.941430 60262 negative regulation of N-terminal protein palmitoylation 0.941426 60254 regulation of N-terminal protein palmitoylation 0.941426 48514 blood vessel morphogenesis 0.941426 45294 alpha-catenin binding 0.941405 5127 ciliary neurotrophic factor receptor binding 0.941356 42509 regulation of tyrosine phosphorylation of STAT protein 0.941355 34187 apolipoprotein E binding 0.941327 42310 vasoconstriction 0.941299 42594 response to starvation 0.941279 45061 thymic T cell selection 0.941250 31146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 0.941233 42032 cytokine biosynthetic process 0.941231 10862 positive regulation of pathway-restricted SMAD protein phosphorylation 0.941183 51051 negative regulation of transport 0.941158 16199 axon midline choice point recognition 0.941137 7183 SMAD protein complex assembly 0.941117 8295 spermidine biosynthetic process 0.941099 30916 otic vesicle formation 0.941099 7388 posterior compartment specification 0.941088 7387 anterior compartment specification 0.941088 45585 positive regulation of cytotoxic T cell differentiation 0.941040 45583 regulation of cytotoxic T cell differentiation 0.941040 43535 regulation of blood vessel endothelial cell migration 0.940993 19896 axon transport of mitochondrion 0.940970 8545 JUN kinase kinase activity 0.940944 47837 D-xylose 1-dehydrogenase (NADP+) activity 0.940895 48664 neuron fate determination 0.940884 21999 neural plate anterior/posterior pattern formation 0.940847 21997 neural plate axis specification 0.940847 70070 proton-transporting V-type ATPase complex assembly 0.940844 70072 vacuolar proton-transporting V-type ATPase complex assembly 0.940844 50848 regulation of calcium-mediated signaling 0.940831 10889 regulation of sequestering of triglyceride 0.940816 8792 arginine decarboxylase activity 0.940799 45236 CXCR chemokine receptor binding 0.940796 5153 interleukin-8 receptor binding 0.940796 30898 actin-dependent ATPase activity 0.940792 50829 defense response to Gram-negative bacterium 0.940754 8623 chromatin accessibility complex 0.940750 8622 epsilon DNA polymerase complex 0.940750 31503 protein complex localization 0.940700 22616 DNA strand elongation 0.940694 45741 positive regulation of epidermal growth factor receptor activity 0.940681 45410 positive regulation of interleukin-6 biosynthetic process 0.940671 32224 positive regulation of synaptic transmission, cholinergic 0.940654 19439 aromatic compound catabolic process 0.940648 33504 floor plate development 0.940606 21919 BMP signaling pathway in spinal cord dorsal/ventral patterning 0.940606 8652 cellular amino acid biosynthetic process 0.940577 34552 respiratory chain complex II assembly 0.940557 34553 mitochondrial respiratory chain complex II assembly 0.940557 2831 regulation of response to biotic stimulus 0.940552 6572 tyrosine catabolic process 0.940526 47066 phospholipid-hydroperoxide glutathione peroxidase activity 0.940509 33631 cell-cell adhesion mediated by integrin 0.940503 45987 positive regulation of smooth muscle contraction 0.940491 16728 oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor 0.940464 4748 ribonucleoside-diphosphate reductase activity 0.940464 45862 positive regulation of proteolysis 0.940442 47115 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity 0.940428 18076 N-terminal peptidyl-lysine acetylation 0.940423 18394 peptidyl-lysine acetylation 0.940423 4510 tryptophan 5-monooxygenase activity 0.940385 42427 serotonin biosynthetic process 0.940385 43526 neuroprotection 0.940382 43604 amide biosynthetic process 0.940375 50773 regulation of dendrite development 0.940366 30335 positive regulation of cell migration 0.940307 45008 depyrimidination 0.940304 15207 adenine transmembrane transporter activity 0.940265 19674 NAD metabolic process 0.940224 45735 nutrient reservoir activity 0.940219 9841 mitochondrial endopeptidase Clp complex 0.940171 9368 endopeptidase Clp complex 0.940171 30573 bile acid catabolic process 0.940133 45906 negative regulation of vasoconstriction 0.940096 42035 regulation of cytokine biosynthetic process 0.940095 33798 thyroxine 5-deiodinase activity 0.940074 7468 regulation of rhodopsin gene expression 0.940047 46473 phosphatidic acid metabolic process 0.940028 18410 peptide or protein carboxyl-terminal blocking 0.939999 6481 C-terminal protein amino acid methylation 0.939999 3880 C-terminal protein carboxyl methyltransferase activity 0.939999 44271 cellular nitrogen compound biosynthetic process 0.939999 32402 melanosome transport 0.939953 51904 pigment granule transport 0.939953 791 euchromatin 0.939951 42404 thyroid hormone catabolic process 0.939878 8275 gamma-tubulin small complex 0.939833 45670 regulation of osteoclast differentiation 0.939812 45159 myosin II binding 0.939795 6198 cAMP catabolic process 0.939731 31122 cytoplasmic microtubule organization 0.939728 48525 negative regulation of viral reproduction 0.939726 43109 regulation of smoothened signaling pathway 0.939725 7226 regulation of smoothened signaling pathway 0.939725 30279 negative regulation of ossification 0.939712 45885 positive regulation of survival gene product expression 0.939700 60151 peroxisome localization 0.939661 60152 microtubule-based peroxisome localization 0.939661 101 sulfur amino acid transport 0.939631 2695 negative regulation of leukocyte activation 0.939618 46853 inositol and derivative phosphorylation 0.939613 6772 thiamin metabolic process 0.939521 70168 negative regulation of biomineral formation 0.939512 30502 negative regulation of bone mineralization 0.939512 6980 response to redox state 0.939510 723 telomere maintenance 0.939502 48604 fibroblast growth factor 3 binding 0.939495 48602 fibroblast growth factor 1 binding 0.939495 50321 tau-protein kinase activity 0.939474 4392 heme oxygenase (decyclizing) activity 0.939468 6788 heme oxidation 0.939468 42575 DNA polymerase complex 0.939464 50720 interleukin-1 beta biosynthetic process 0.939447 42222 interleukin-1 biosynthetic process 0.939447 22417 protein maturation by protein folding 0.939396 70704 sterol desaturase activity 0.939395 248 C-5 sterol desaturase activity 0.939395 31234 extrinsic to internal side of plasma membrane 0.939360 43547 positive regulation of GTPase activity 0.939351 8392 arachidonic acid epoxygenase activity 0.939350 8391 arachidonic acid monooxygenase activity 0.939350 9309 amine biosynthetic process 0.939331 45744 negative regulation of G-protein coupled receptor protein signaling pathway 0.939323 4119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity 0.939323 46427 positive regulation of JAK-STAT cascade 0.939297 48748 eye morphogenesis 0.939272 4642 phosphoribosylformylglycinamidine synthase activity 0.939253 42447 hormone catabolic process 0.939227 8709 7-alpha-hydroxysteroid dehydrogenase activity 0.939205 47015 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity 0.939205 8422 beta-glucosidase activity 0.939183 30619 U1 snRNA binding 0.939157 5685 U1 snRNP 0.939157 15485 cholesterol binding 0.939152 60053 neurofilament cytoskeleton 0.939109 45030 UTP-activated nucleotide receptor activity 0.939060 51272 positive regulation of cellular component movement 0.939019 8457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity 0.939012 8917 lipopolysaccharide N-acetylglucosaminyltransferase activity 0.939012 9331 glycerol-3-phosphate dehydrogenase complex 0.939006 46128 purine ribonucleoside metabolic process 0.938989 42278 purine nucleoside metabolic process 0.938989 1942 hair follicle development 0.938988 31095 platelet dense tubular network membrane 0.938974 5220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity 0.938974 48639 positive regulation of developmental growth 0.938972 6991 response to sterol depletion 0.938937 32933 SREBP-mediated signaling pathway 0.938937 71501 cellular response to sterol depletion 0.938937 30967 ER-nuclear sterol response pathway 0.938937 1740 Barr body 0.938912 803 sex chromosome 0.938912 805 X chromosome 0.938912 30578 PML body organization 0.938864 30575 nuclear body organization 0.938864 9396 folic acid and derivative biosynthetic process 0.938844 16749 N-succinyltransferase activity 0.938840 3870 5-aminolevulinate synthase activity 0.938840 4751 ribose-5-phosphate isomerase activity 0.938819 9052 pentose-phosphate shunt, non-oxidative branch 0.938819 60571 morphogenesis of an epithelial fold 0.938816 1842 neural fold formation 0.938816 34968 histone lysine methylation 0.938797 33157 regulation of intracellular protein transport 0.938779 10833 telomere maintenance via telomere lengthening 0.938778 22407 regulation of cell-cell adhesion 0.938700 48640 negative regulation of developmental growth 0.938689 30517 negative regulation of axon extension 0.938689 31397 negative regulation of protein ubiquitination 0.938684 4765 shikimate kinase activity 0.938671 6835 dicarboxylic acid transport 0.938646 9267 cellular response to starvation 0.938642 34012 FAD-AMP lyase (cyclizing) activity 0.938626 4371 glycerone kinase activity 0.938626 31958 corticosteroid receptor signaling pathway 0.938560 42921 glucocorticoid receptor signaling pathway 0.938560 60013 righting reflex 0.938555 4801 transaldolase activity 0.938529 42532 negative regulation of tyrosine phosphorylation of STAT protein 0.938520 42518 negative regulation of tyrosine phosphorylation of Stat3 protein 0.938520 9166 nucleotide catabolic process 0.938519 2449 lymphocyte mediated immunity 0.938516 51250 negative regulation of lymphocyte activation 0.938508 60324 face development 0.938478 47220 galactosylxylosylprotein 3-beta-galactosyltransferase activity 0.938433 70052 collagen V binding 0.938430 6583 melanin biosynthetic process from tyrosine 0.938405 48246 macrophage chemotaxis 0.938387 51204 protein insertion into mitochondrial membrane 0.938381 48771 tissue remodeling 0.938357 47963 glycine N-choloyltransferase activity 0.938336 51645 Golgi localization 0.938288 45945 positive regulation of transcription from RNA polymerase III promoter 0.938239 33093 Weibel-Palade body 0.938212 34969 histone arginine methylation 0.938208 45747 positive regulation of Notch signaling pathway 0.938182 50830 defense response to Gram-positive bacterium 0.938143 70259 tyrosyl-DNA phosphodiesterase activity 0.938143 17005 3'-tyrosyl-DNA phosphodiesterase activity 0.938143 50863 regulation of T cell activation 0.938143 1934 positive regulation of protein amino acid phosphorylation 0.938124 34394 protein localization at cell surface 0.938098 109 nucleotide-excision repair complex 0.938098 8542 visual learning 0.938095 1839 neural plate morphogenesis 0.938095 1302 replicative cell aging 0.938092 42732 D-xylose metabolic process 0.938092 45334 clathrin-coated endocytic vesicle 0.938072 19362 pyridine nucleotide metabolic process 0.938052 48179 activin receptor complex 0.938043 21979 hypothalamus cell differentiation 0.938040 45600 positive regulation of fat cell differentiation 0.937986 35068 micro-ribonucleoprotein complex 0.937971 31314 extrinsic to mitochondrial inner membrane 0.937950 10829 negative regulation of glucose transport 0.937926 7628 adult walking behavior 0.937875 19959 interleukin-8 binding 0.937863 19104 DNA N-glycosylase activity 0.937836 51249 regulation of lymphocyte activation 0.937829 6577 betaine metabolic process 0.937812 9437 carnitine metabolic process 0.937812 10302 2-oxoglutarate-dependent dioxygenase activity 0.937805 51747 DNA demethylase activity 0.937805 42119 neutrophil activation 0.937802 1708 cell fate specification 0.937720 33267 axon part 0.937713 51495 positive regulation of cytoskeleton organization 0.937693 35315 hair cell differentiation 0.937686 50655 dermatan sulfate proteoglycan metabolic process 0.937657 17163 basal transcription repressor activity 0.937633 22011 myelination in the peripheral nervous system 0.937622 32292 ensheathment of axons in the peripheral nervous system 0.937622 43392 negative regulation of DNA binding 0.937582 42306 regulation of protein import into nucleus 0.937576 30206 chondroitin sulfate biosynthetic process 0.937566 60351 cartilage development involved in endochondral bone morphogenesis 0.937563 70419 nonhomologous end joining complex 0.937551 5958 DNA-dependent protein kinase-DNA ligase 4 complex 0.937551 44270 cellular nitrogen compound catabolic process 0.937539 21854 hypothalamus development 0.937509 50796 regulation of insulin secretion 0.937503 15850 organic alcohol transport 0.937492 45851 pH reduction 0.937478 51044 positive regulation of membrane protein ectodomain proteolysis 0.937464 6288 base-excision repair, DNA ligation 0.937464 7529 establishment of synaptic specificity at neuromuscular junction 0.937440 4380 glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity 0.937419 4381 fucosylgalactoside 3-alpha-galactosyltransferase activity 0.937419 10563 negative regulation of phosphorus metabolic process 0.937379 45936 negative regulation of phosphate metabolic process 0.937379 3842 1-pyrroline-5-carboxylate dehydrogenase activity 0.937370 50774 negative regulation of dendrite morphogenesis 0.937367 6983 ER overload response 0.937351 47316 glutamine-phenylpyruvate transaminase activity 0.937322 32200 telomere organization 0.937313 4040 amidase activity 0.937271 9119 ribonucleoside metabolic process 0.937260 46487 glyoxylate metabolic process 0.937250 43269 regulation of ion transport 0.937248 15278 calcium-release channel activity 0.937244 48245 eosinophil chemotaxis 0.937225 7035 vacuolar acidification 0.937219 8074 guanylate cyclase complex, soluble 0.937174 35082 axoneme assembly 0.937132 7019 microtubule depolymerization 0.937102 51261 protein depolymerization 0.937102 1937 negative regulation of endothelial cell proliferation 0.937083 48265 response to pain 0.937063 43008 ATP-dependent protein binding 0.937053 32038 myosin II heavy chain binding 0.937053 15579 glucose transmembrane transporter activity 0.937005 3845 11-beta-hydroxysteroid dehydrogenase activity 0.937005 5412 glucose:sodium symporter activity 0.937005 47743 chlordecone reductase activity 0.936984 70201 regulation of establishment of protein localization 0.936917 15732 prostaglandin transport 0.936887 15132 prostaglandin transmembrane transporter activity 0.936887 6699 bile acid biosynthetic process 0.936875 45655 regulation of monocyte differentiation 0.936860 45657 positive regulation of monocyte differentiation 0.936860 51588 regulation of neurotransmitter transport 0.936798 46534 positive regulation of photoreceptor cell differentiation 0.936791 17096 acetylserotonin O-methyltransferase activity 0.936788 30658 transport vesicle membrane 0.936779 42017 interleukin-22 binding 0.936742 42018 interleukin-22 receptor activity 0.936742 42326 negative regulation of phosphorylation 0.936731 42268 regulation of cytolysis 0.936721 60341 regulation of cellular localization 0.936710 60061 Spemann organizer formation 0.936694 60064 Spemann organizer formation at the anterior end of the primitive streak 0.936694 21778 oligodendrocyte cell fate specification 0.936672 21780 glial cell fate specification 0.936672 21530 spinal cord oligodendrocyte cell fate specification 0.936672 35095 behavioral response to nicotine 0.936669 31054 pre-microRNA processing 0.936663 1946 lymphangiogenesis 0.936649 4362 glutathione-disulfide reductase activity 0.936646 60021 palate development 0.936629 5008 hepatocyte growth factor receptor activity 0.936598 6654 phosphatidic acid biosynthetic process 0.936588 51150 regulation of smooth muscle cell differentiation 0.936556 35248 alpha-1,4-N-acetylgalactosaminyltransferase activity 0.936501 43433 negative regulation of transcription factor activity 0.936492 90048 negative regulation of transcription regulator activity 0.936492 50353 trimethyllysine dioxygenase activity 0.936453 42830 defense response to bacterium 0.936446 6978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator 0.936434 42772 DNA damage response, signal transduction resulting in transcription 0.936434 10332 response to gamma radiation 0.936413 46692 sperm competition 0.936404 7321 sperm displacement 0.936404 15811 L-cystine transport 0.936382 266 mitochondrial fission 0.936371 8265 Mo-molybdopterin cofactor sulfurase activity 0.936356 48638 regulation of developmental growth 0.936327 42135 neurotransmitter catabolic process 0.936304 60022 hard palate development 0.936260 30224 monocyte differentiation 0.936257 60746 parental behavior 0.936232 42711 maternal behavior 0.936232 10815 bradykinin catabolic process 0.936208 4675 transmembrane receptor protein serine/threonine kinase activity 0.936195 5024 transforming growth factor beta receptor activity 0.936195 6097 glyoxylate cycle 0.936136 4450 isocitrate dehydrogenase (NADP+) activity 0.936136 5161 platelet-derived growth factor receptor binding 0.936130 46599 regulation of centriole replication 0.936125 4311 farnesyltranstransferase activity 0.936093 31623 receptor internalization 0.936027 51223 regulation of protein transport 0.936024 50815 phosphoserine binding 0.936021 33767 4-hydroxyacetophenone monooxygenase activity 0.936015 18676 (S)-limonene 7-monooxygenase activity 0.936015 18675 (S)-limonene 6-monooxygenase activity 0.936015 19113 limonene monooxygenase activity 0.936015 6700 C21-steroid hormone biosynthetic process 0.935979 16314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity 0.935918 34594 phosphatidylinositol trisphosphate phosphatase activity 0.935918 10858 calcium-dependent protein kinase regulator activity 0.935873 8427 calcium-dependent protein kinase inhibitor activity 0.935873 46549 retinal cone cell development 0.935851 33778 7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity 0.935825 8397 sterol 12-alpha-hydroxylase activity 0.935825 10793 regulation of mRNA export from nucleus 0.935777 8282 ATP-sensitive potassium channel complex 0.935771 15458 potassium ion transport 0.935771 10107 potassium ion import 0.935771 60285 ciliary cell motility 0.935749 30731 guanidinoacetate N-methyltransferase activity 0.935680 19747 regulation of isoprenoid metabolic process 0.935632 60334 regulation of interferon-gamma-mediated signaling pathway 0.935610 16898 oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor 0.935584 4458 D-lactate dehydrogenase (cytochrome) activity 0.935584 48185 activin binding 0.935580 16854 racemase and epimerase activity 0.935569 46825 regulation of protein export from nucleus 0.935520 50121 N-acylglucosamine 2-epimerase activity 0.935487 6555 methionine metabolic process 0.935450 45738 negative regulation of DNA repair 0.935439 32320 positive regulation of Ras GTPase activity 0.935379 16534 cyclin-dependent protein kinase 5 activator activity 0.935363 16533 cyclin-dependent protein kinase 5 holoenzyme complex 0.935363 48592 eye morphogenesis 0.935349 43900 regulation of multi-organism process 0.935327 45669 positive regulation of osteoblast differentiation 0.935302 43496 regulation of protein homodimerization activity 0.935294 6409 tRNA export from nucleus 0.935246 51031 tRNA transport 0.935246 42573 retinoic acid metabolic process 0.935215 2764 immune response-regulating signal transduction 0.935206 48636 positive regulation of muscle organ development 0.935194 45844 positive regulation of striated muscle tissue development 0.935194 51130 positive regulation of cellular component organization 0.935175 4824 lysine-tRNA ligase activity 0.935149 6430 lysyl-tRNA aminoacylation 0.935149 10596 negative regulation of endothelial cell migration 0.935137 4066 asparagine synthase (glutamine-hydrolyzing) activity 0.935122 6529 asparagine biosynthetic process 0.935122 35021 negative regulation of Rac protein signal transduction 0.935101 34341 response to interferon-gamma 0.935097 4819 glutamine-tRNA ligase activity 0.935052 6425 glutaminyl-tRNA aminoacylation 0.935052 4924 oncostatin-M receptor activity 0.935046 10959 regulation of metal ion transport 0.935041 21757 caudate nucleus development 0.935004 21758 putamen development 0.935004 48593 camera-type eye morphogenesis 0.935000 3691 double-stranded telomeric DNA binding 0.934982 9218 pyrimidine ribonucleotide metabolic process 0.934977 4164 diphthine synthase activity 0.934956 50858 negative regulation of antigen receptor-mediated signaling pathway 0.934950 50860 negative regulation of T cell receptor signaling pathway 0.934950 45792 negative regulation of cell size 0.934934 22602 ovulation cycle process 0.934923 48872 homeostasis of number of cells 0.934918 6085 acetyl-CoA biosynthetic process 0.934917 8280 cohesin core heterodimer 0.934908 46037 GMP metabolic process 0.934901 6177 GMP biosynthetic process 0.934901 47977 hepoxilin-epoxide hydrolase activity 0.934880 51899 membrane depolarization 0.934869 6121 mitochondrial electron transport, succinate to ubiquinone 0.934811 18293 protein-FAD linkage 0.934811 45329 carnitine biosynthetic process 0.934808 6725 cellular aromatic compound metabolic process 0.934768 4372 glycine hydroxymethyltransferase activity 0.934765 31639 plasminogen activation 0.934741 15211 purine nucleoside transmembrane transporter activity 0.934735 18153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine 0.934687 18199 peptidyl-glutamine modification 0.934687 18262 isopeptide cross-linking 0.934687 9214 cyclic nucleotide catabolic process 0.934681 8578 DNA N-glycosylase activity 0.934662 21955 central nervous system neuron axonogenesis 0.934638 21952 central nervous system projection neuron axonogenesis 0.934638 4104 cholinesterase activity 0.934628 8489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity 0.934618 3851 2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity 0.934618 40014 regulation of multicellular organism growth 0.934603 8172 S-methyltransferase activity 0.934599 19534 toxin transporter activity 0.934566 51292 nuclear pore complex assembly 0.934566 16234 inclusion body 0.934499 45638 negative regulation of myeloid cell differentiation 0.934478 5585 collagen type II 0.934425 45767 regulation of anti-apoptosis 0.934415 16880 acid-ammonia (or amide) ligase activity 0.934402 16211 ammonia ligase activity 0.934402 43616 keratinocyte proliferation 0.934396 7352 zygotic determination of dorsal/ventral axis 0.934338 45639 positive regulation of myeloid cell differentiation 0.934332 1772 immunological synapse 0.934275 31559 oxidosqualene cyclase activity 0.934231 250 lanosterol synthase activity 0.934231 6600 creatine metabolic process 0.934222 6599 phosphagen metabolic process 0.934222 51151 negative regulation of smooth muscle cell differentiation 0.934161 31086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay 0.934135 31087 deadenylation-independent decapping of nuclear-transcribed mRNA 0.934135 18130 heterocycle biosynthetic process 0.934115 55012 ventricular cardiac muscle cell differentiation 0.934108 4891 extracellular-glycine-gated chloride channel activity 0.934087 46131 pyrimidine ribonucleoside metabolic process 0.934078 17146 N-methyl-D-aspartate selective glutamate receptor complex 0.934063 8574 plus-end-directed microtubule motor activity 0.934059 8532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity 0.934038 4563 beta-N-acetylhexosaminidase activity 0.934029 18210 peptidyl-threonine modification 0.934007 8207 C21-steroid hormone metabolic process 0.933976 50730 regulation of peptidyl-tyrosine phosphorylation 0.933975 42133 neurotransmitter metabolic process 0.933966 14812 muscle cell migration 0.933963 8745 N-acetylmuramoyl-L-alanine amidase activity 0.933956 18146 keratan sulfate biosynthetic process 0.933942 31401 positive regulation of protein modification process 0.933926 31577 spindle checkpoint 0.933923 45841 negative regulation of mitotic metaphase/anaphase transition 0.933923 71173 spindle assembly checkpoint 0.933923 71174 mitotic cell cycle spindle checkpoint 0.933923 7094 mitotic cell cycle spindle assembly checkpoint 0.933923 51377 mannose-ethanolamine phosphotransferase activity 0.933893 51267 CP2 mannose-ethanolamine phosphotransferase activity 0.933893 8209 androgen metabolic process 0.933855 10171 body morphogenesis 0.933845 10172 embryonic body morphogenesis 0.933845 45927 positive regulation of growth 0.933839 45879 negative regulation of smoothened signaling pathway 0.933818 30311 poly-N-acetyllactosamine biosynthetic process 0.933794 32409 regulation of transporter activity 0.933792 34385 triglyceride-rich lipoprotein particle 0.933775 34361 very-low-density lipoprotein particle 0.933775 18 regulation of DNA recombination 0.933763 34416 bisphosphoglycerate phosphatase activity 0.933745 4615 phosphomannomutase activity 0.933745 19307 mannose biosynthetic process 0.933745 90100 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 0.933718 16269 O-glycan processing, core 3 0.933700 1530 lipopolysaccharide binding 0.933681 4534 5'-3' exoribonuclease activity 0.933652 7004 telomere maintenance via telomerase 0.933637 43584 nose development 0.933576 3874 6-pyruvoyltetrahydropterin synthase activity 0.933555 60048 cardiac muscle contraction 0.933546 51247 positive regulation of protein metabolic process 0.933543 16262 protein N-acetylglucosaminyltransferase activity 0.933507 35235 ionotropic glutamate receptor signaling pathway 0.933475 35244 peptidyl-arginine C-methyltransferase activity 0.933459 15382 sodium:sulfate symporter activity 0.933411 50435 beta-amyloid metabolic process 0.933404 8045 motor axon guidance 0.933390 5142 interleukin-11 receptor binding 0.933362 4917 interleukin-7 receptor activity 0.933311 19982 interleukin-7 binding 0.933311 70988 demethylation 0.933302 8214 protein amino acid dealkylation 0.933302 6482 protein amino acid demethylation 0.933302 6408 snRNA export from nucleus 0.933263 51030 snRNA transport 0.933263 9075 histidine family amino acid metabolic process 0.933207 6547 histidine metabolic process 0.933207 43409 negative regulation of MAPKKK cascade 0.933207 16019 peptidoglycan receptor activity 0.933205 35137 hindlimb morphogenesis 0.933181 9743 response to carbohydrate stimulus 0.933179 4461 lactose synthase activity 0.933179 42089 cytokine biosynthetic process 0.933172 16934 extracellular-glycine-gated chloride channel activity 0.933159 16933 extracellular-glycine-gated ion channel activity 0.933159 5237 inhibitory extracellular ligand-gated ion channel activity 0.933159 35249 synaptic transmission, glutamatergic 0.933147 3018 vascular process in circulatory system 0.933135 8336 gamma-butyrobetaine dioxygenase activity 0.933121 18198 peptidyl-cysteine modification 0.933098 46716 muscle homeostasis 0.933093 45872 positive regulation of rhodopsin gene expression 0.933073 2757 immune response-activating signal transduction 0.933072 51924 regulation of calcium ion transport 0.933033 31994 insulin-like growth factor I binding 0.933031 15350 methotrexate transporter activity 0.933024 1707 mesoderm formation 0.932982 45071 negative regulation of viral genome replication 0.932920 8296 3'-5'-exodeoxyribonuclease activity 0.932857 15327 cystine:glutamate antiporter activity 0.932783 46902 regulation of mitochondrial membrane permeability 0.932770 7224 smoothened signaling pathway 0.932758 8613 diuretic hormone activity 0.932735 16826 hydrolase activity, acting on acid sulfur-nitrogen bonds 0.932686 16250 N-sulfoglucosamine sulfohydrolase activity 0.932686 50656 3'-phosphoadenosine 5'-phosphosulfate binding 0.932654 30325 adrenal gland development 0.932612 6639 acylglycerol metabolic process 0.932590 6638 neutral lipid metabolic process 0.932590 722 telomere maintenance via recombination 0.932590 1532 interleukin-21 receptor activity 0.932541 19977 interleukin-21 binding 0.932541 43558 regulation of translational initiation in response to stress 0.932538 43555 regulation of translation in response to stress 0.932538 46625 sphingolipid binding 0.932535 2274 myeloid leukocyte activation 0.932528 19369 arachidonic acid metabolic process 0.932520 1958 endochondral ossification 0.932503 70064 proline-rich region binding 0.932495 9950 dorsal/ventral axis specification 0.932487 30593 neutrophil chemotaxis 0.932484 8260 3-oxoacid CoA-transferase activity 0.932442 8410 CoA-transferase activity 0.932442 46950 cellular ketone body metabolic process 0.932442 46952 ketone body catabolic process 0.932442 70531 BRCA1-A complex 0.932439 32092 positive regulation of protein binding 0.932383 19008 molybdopterin synthase complex 0.932369 7518 myoblast cell fate determination 0.932345 40020 regulation of meiosis 0.932345 50900 leukocyte migration 0.932315 32410 negative regulation of transporter activity 0.932300 7136 meiotic prophase II 0.932203 32404 mismatch repair complex binding 0.932162 19103 pyrimidine nucleotide binding 0.932128 43628 ncRNA 3'-end processing 0.932085 70661 leukocyte proliferation 0.932058 32943 mononuclear cell proliferation 0.932058 42745 circadian sleep/wake cycle 0.932010 32270 positive regulation of cellular protein metabolic process 0.932008 34260 negative regulation of GTPase activity 0.931983 34261 negative regulation of Ras GTPase activity 0.931983 34259 negative regulation of Rho GTPase activity 0.931983 48568 embryonic organ development 0.931969 42766 nucleosome mobilization 0.931914 31372 UBC13-MMS2 complex 0.931814 48484 enteric nervous system development 0.931810 5310 dicarboxylic acid transmembrane transporter activity 0.931792 6167 AMP biosynthetic process 0.931778 32386 regulation of intracellular transport 0.931777 4493 methylmalonyl-CoA epimerase activity 0.931769 46491 L-methylmalonyl-CoA metabolic process 0.931769 4368 glycerol-3-phosphate dehydrogenase activity 0.931766 43537 negative regulation of blood vessel endothelial cell migration 0.931740 48745 smooth muscle tissue development 0.931727 43000 Golgi to plasma membrane CFTR protein transport 0.931721 48009 insulin-like growth factor receptor signaling pathway 0.931709 16649 oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor 0.931693 4174 electron-transferring-flavoprotein dehydrogenase activity 0.931693 30947 regulation of vascular endothelial growth factor receptor signaling pathway 0.931683 46475 glycerophospholipid catabolic process 0.931682 71322 cellular response to carbohydrate stimulus 0.931669 9756 carbohydrate mediated signaling 0.931669 8521 acetyl-CoA transporter activity 0.931624 51185 coenzyme transporter activity 0.931624 21985 neurohypophysis development 0.931572 45323 interleukin-1 receptor complex 0.931456 5554 molecular_function 0.931439 60263 regulation of respiratory burst 0.931432 46469 platelet activating factor metabolic process 0.931409 379 tRNA-type intron splice site recognition and cleavage 0.931382 51641 cellular localization 0.931356 4333 fumarate hydratase activity 0.931334 51640 organelle localization 0.931312 50792 regulation of viral reproduction 0.931308 2080 acrosomal membrane 0.931286 5217 intracellular ligand-gated ion channel activity 0.931250 9220 pyrimidine ribonucleotide biosynthetic process 0.931242 16598 protein arginylation 0.931238 4057 arginyltransferase activity 0.931238 16274 protein-arginine N-methyltransferase activity 0.931197 16273 arginine N-methyltransferase activity 0.931197 60033 anatomical structure regression 0.931191 4919 interleukin-9 receptor activity 0.931189 19983 interleukin-9 binding 0.931189 8211 glucocorticoid metabolic process 0.931179 45791 cell morphogenesis 0.931152 45790 cell morphogenesis 0.931152 7148 cell morphogenesis 0.931152 6271 DNA strand elongation during DNA replication 0.931150 4470 malic enzyme activity 0.931119 18112 proline racemase activity 0.931093 31932 TORC2 complex 0.931089 31074 nucleocytoplasmic shuttling complex 0.931089 32023 trypsinogen activation 0.931044 50982 detection of mechanical stimulus 0.931042 19363 pyridine nucleotide biosynthetic process 0.931036 6651 diacylglycerol biosynthetic process 0.930998 50916 sensory perception of sweet taste 0.930993 33483 gas homeostasis 0.930971 5171 hepatocyte growth factor receptor binding 0.930948 15643 toxin binding 0.930938 43047 single-stranded telomeric DNA binding 0.930896 16895 exodeoxyribonuclease activity, producing 5'-phosphomonoesters 0.930864 4529 exodeoxyribonuclease activity 0.930864 51049 regulation of transport 0.930864 70097 delta-catenin binding 0.930851 30893 meiotic cohesin complex 0.930848 50880 regulation of blood vessel size 0.930840 35150 regulation of tube size 0.930840 48030 disaccharide binding 0.930803 30395 lactose binding 0.930803 10447 response to acidity 0.930755 32266 phosphatidylinositol 3-phosphate binding 0.930741 30586 [methionine synthase] reductase activity 0.930706 30309 poly-N-acetyllactosamine metabolic process 0.930700 35116 embryonic hindlimb morphogenesis 0.930696 4613 phosphoenolpyruvate carboxykinase (GTP) activity 0.930679 4611 phosphoenolpyruvate carboxykinase activity 0.930679 43587 tongue morphogenesis 0.930668 1657 ureteric bud development 0.930663 7129 synapsis 0.930660 51289 protein homotetramerization 0.930616 16857 racemase and epimerase activity, acting on carbohydrates and derivatives 0.930604 30368 interleukin-17 receptor activity 0.930562 19975 interleukin-17 binding 0.930562 6012 galactose metabolic process 0.930514 2291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 0.930510 42448 progesterone metabolic process 0.930488 70215 MDM2 binding 0.930465 48714 positive regulation of oligodendrocyte differentiation 0.930417 50663 cytokine secretion 0.930370 4810 tRNA adenylyltransferase activity 0.930368 904 cell morphogenesis involved in differentiation 0.930343 50333 thiamin-triphosphatase activity 0.930320 46325 negative regulation of glucose import 0.930309 21602 cranial nerve morphogenesis 0.930303 8593 regulation of Notch signaling pathway 0.930300 35058 sensory cilium assembly 0.930249 2087 regulation of respiratory gaseous exchange by neurological system process 0.930217 44065 regulation of respiratory system process 0.930217 6740 NADPH regeneration 0.930210 10552 positive regulation of gene-specific transcription from RNA polymerase II promoter 0.930207 7410 axonogenesis 0.930207 1941 postsynaptic membrane organization 0.930175 50955 thermoception 0.930148 50951 sensory perception of temperature stimulus 0.930148 30899 calcium-dependent ATPase activity 0.930127 45648 positive regulation of erythrocyte differentiation 0.930111 34612 response to tumor necrosis factor 0.930094 10225 response to UV-C 0.930046 6766 vitamin metabolic process 0.930033 1847 opsonin receptor activity 0.930030 9310 amine catabolic process 0.930022 6221 pyrimidine nucleotide biosynthetic process 0.930017 42720 mitochondrial inner membrane peptidase complex 0.929982 42405 nuclear inclusion body 0.929975 51648 vesicle localization 0.929959 55081 anion homeostasis 0.929958 9917 sterol 5-alpha reductase activity 0.929934 215 tRNA 2'-phosphotransferase activity 0.929886 46425 regulation of JAK-STAT cascade 0.929824 43001 Golgi to plasma membrane protein transport 0.929810 51224 negative regulation of protein transport 0.929800 2792 negative regulation of peptide secretion 0.929796 46676 negative regulation of insulin secretion 0.929796 46580 negative regulation of Ras protein signal transduction 0.929769 51058 negative regulation of small GTPase mediated signal transduction 0.929769 6244 pyrimidine nucleotide catabolic process 0.929729 16577 histone demethylation 0.929700 921 septin ring assembly 0.929692 34613 cellular protein localization 0.929679 43299 leukocyte degranulation 0.929663 9360 DNA polymerase III complex 0.929596 10948 negative regulation of cell cycle process 0.929582 4820 glycine-tRNA ligase activity 0.929544 6426 glycyl-tRNA aminoacylation 0.929544 17157 regulation of exocytosis 0.929502 33783 25-hydroxycholesterol 7alpha-hydroxylase activity 0.929499 3948 N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity 0.929472 15926 glucosidase activity 0.929365 42835 BRE binding 0.929303 10842 retina layer formation 0.929258 19098 reproductive behavior 0.929257 45523 interleukin-27 receptor binding 0.929206 43498 cell surface binding 0.929183 21587 cerebellum morphogenesis 0.929158 45214 sarcomere organization 0.929155 46822 regulation of nucleocytoplasmic transport 0.929142 70545 PeBoW complex 0.929138 463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 0.929138 470 maturation of LSU-rRNA 0.929138 32835 glomerulus development 0.929106 45995 regulation of embryonic development 0.929000 46165 alcohol biosynthetic process 0.928986 8815 citrate (pro-3S)-lyase activity 0.928892 9346 citrate lyase complex 0.928892 5971 ribonucleoside-diphosphate reductase complex 0.928872 51918 negative regulation of fibrinolysis 0.928867 42474 middle ear morphogenesis 0.928860 48240 sperm capacitation 0.928849 8316 structural constituent of vitelline membrane 0.928823 30704 vitelline membrane formation 0.928823 46500 S-adenosylmethionine metabolic process 0.928780 7196 inhibition of adenylate cyclase activity by metabotropic glutamate receptor signaling pathway 0.928727 8244 protein prenyltransferase activity 0.928706 16530 metallochaperone activity 0.928680 16597 amino acid binding 0.928665 16900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor 0.928630 47057 vitamin-K-epoxide reductase (warfarin-sensitive) activity 0.928630 4905 type I interferon receptor activity 0.928627 19962 type I interferon binding 0.928627 1704 formation of primary germ layer 0.928615 4913 interleukin-4 receptor activity 0.928602 19979 interleukin-4 binding 0.928602 4167 dopachrome isomerase activity 0.928559 8798 beta-aspartyl-peptidase activity 0.928533 30002 cellular anion homeostasis 0.928527 5072 transforming growth factor beta receptor, cytoplasmic mediator activity 0.928525 42780 tRNA 3'-end processing 0.928506 48187 inhibin beta-B binding 0.928485 31312 extrinsic to organelle membrane 0.928482 70513 death domain binding 0.928481 5865 striated muscle thin filament 0.928437 8124 4-alpha-hydroxytetrahydrobiopterin dehydratase activity 0.928385 16815 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in nitriles 0.928340 257 nitrilase activity 0.928340 6970 response to osmotic stress 0.928337 47756 chondroitin 4-sulfotransferase activity 0.928301 1641 group II metabotropic glutamate receptor activity 0.928292 14 single-stranded DNA specific endodeoxyribonuclease activity 0.928285 51094 positive regulation of developmental process 0.928284 51917 regulation of fibrinolysis 0.928232 45722 positive regulation of gluconeogenesis 0.928216 1947 heart looping 0.928204 15108 chloride transmembrane transporter activity 0.928195 32321 positive regulation of Rho GTPase activity 0.928192 43425 bHLH transcription factor binding 0.928186 32880 regulation of protein localization 0.928184 4992 platelet activating factor receptor activity 0.928156 18904 organic ether metabolic process 0.928142 30534 adult behavior 0.928106 6525 arginine metabolic process 0.928080 35176 social behavior 0.928063 3952 NAD+ synthase (glutamine-hydrolyzing) activity 0.928051 31528 microvillus membrane 0.928040 60155 platelet dense granule organization 0.928027 21799 cerebral cortex radially oriented cell migration 0.927915 19884 antigen processing and presentation of exogenous antigen 0.927912 16320 endoplasmic reticulum membrane fusion 0.927906 4356 glutamate-ammonia ligase activity 0.927854 6542 glutamine biosynthetic process 0.927854 60395 SMAD protein signal transduction 0.927832 42301 phosphate binding 0.927830 51656 establishment of organelle localization 0.927830 31727 CCR2 chemokine receptor binding 0.927830 48020 CCR chemokine receptor binding 0.927830 21542 dentate gyrus development 0.927802 45090 retroviral genome replication 0.927733 9064 glutamine family amino acid metabolic process 0.927728 32074 negative regulation of nuclease activity 0.927713 44272 sulfur compound biosynthetic process 0.927683 5816 spindle pole body 0.927673 4411 homogentisate 1,2-dioxygenase activity 0.927616 6662 glycerol ether metabolic process 0.927596 6098 pentose-phosphate shunt 0.927550 32862 activation of Rho GTPase activity 0.927547 32856 activation of Ras GTPase activity 0.927547 60271 cilium morphogenesis 0.927519 70207 protein homotrimerization 0.927518 15755 fructose transport 0.927471 9452 RNA capping 0.927467 6220 pyrimidine nucleotide metabolic process 0.927465 16249 cellular protein localization 0.927452 5584 collagen type I 0.927444 70482 response to oxygen levels 0.927437 34284 response to monosaccharide stimulus 0.927436 9749 response to glucose stimulus 0.927436 9746 response to hexose stimulus 0.927436 80010 regulation of oxygen and reactive oxygen species metabolic process 0.927427 439 core TFIIH complex 0.927423 50732 negative regulation of peptidyl-tyrosine phosphorylation 0.927413 70173 regulation of enamel mineralization 0.927375 33013 tetrapyrrole metabolic process 0.927374 6778 porphyrin metabolic process 0.927374 34501 protein localization to kinetochore 0.927368 5223 intracellular cGMP activated cation channel activity 0.927326 7290 spermatid nucleus elongation 0.927323 403 Y-form DNA binding 0.927319 33588 Elongator holoenzyme complex 0.927278 51001 negative regulation of nitric-oxide synthase activity 0.927267 15727 lactate transport 0.927230 9081 branched chain family amino acid metabolic process 0.927207 7062 sister chromatid cohesion 0.927195 4897 ciliary neurotrophic factor receptor activity 0.927183 42339 keratan sulfate metabolic process 0.927154 4420 hydroxymethylglutaryl-CoA reductase (NADPH) activity 0.927133 60314 regulation of ryanodine-sensitive calcium-release channel activity 0.927133 32332 positive regulation of chondrocyte differentiation 0.927119 4753 saccharopine dehydrogenase activity 0.927081 47131 saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity 0.927081 8354 germ cell migration 0.927078 31100 organ regeneration 0.927071 45637 regulation of myeloid cell differentiation 0.927056 43524 negative regulation of neuron apoptosis 0.927044 46039 GTP metabolic process 0.926982 42440 pigment metabolic process 0.926973 18169 ribosomal S6-glutamic acid ligase activity 0.926940 6563 L-serine metabolic process 0.926939 51346 negative regulation of hydrolase activity 0.926900 51248 negative regulation of protein metabolic process 0.926888 30511 positive regulation of transforming growth factor beta receptor signaling pathway 0.926883 2039 p53 binding 0.926875 46650 lymphocyte differentiation 0.926869 34204 lipid translocation 0.926864 45332 phospholipid translocation 0.926864 19216 regulation of lipid metabolic process 0.926850 6576 cellular biogenic amine metabolic process 0.926835 1666 response to hypoxia 0.926772 43031 negative regulation of macrophage activation 0.926767 17174 glycine N-methyltransferase activity 0.926699 43410 positive regulation of MAPKKK cascade 0.926664 32934 sterol binding 0.926660 70402 NADPH binding 0.926650 70304 positive regulation of stress-activated protein kinase signaling pathway 0.926642 80134 regulation of response to stress 0.926617 42779 tRNA 3'-trailer cleavage 0.926602 48286 lung alveolus development 0.926577 15840 urea transport 0.926519 42886 amide transport 0.926519 45597 positive regulation of cell differentiation 0.926482 32051 clathrin light chain binding 0.926457 7095 mitotic cell cycle G2/M transition DNA damage checkpoint 0.926450 4126 cytidine deaminase activity 0.926431 6067 ethanol metabolic process 0.926414 6069 ethanol oxidation 0.926414 34308 monohydric alcohol metabolic process 0.926414 33188 sphingomyelin synthase activity 0.926405 47493 ceramide cholinephosphotransferase activity 0.926405 4766 spermidine synthase activity 0.926381 5139 interleukin-7 receptor binding 0.926361 4645 phosphorylase activity 0.926350 1573 ganglioside metabolic process 0.926281 4463 leukotriene-A4 hydrolase activity 0.926264 47026 3-alpha-hydroxysteroid dehydrogenase (A-specific) activity 0.926260 30902 hindbrain development 0.926206 14003 oligodendrocyte development 0.926160 42359 vitamin D metabolic process 0.926117 3882 CDP-diacylglycerol-serine O-phosphatidyltransferase activity 0.926071 21869 forebrain ventricular zone progenitor cell division 0.926067 6752 group transfer coenzyme metabolic process 0.926047 46651 lymphocyte proliferation 0.925958 32269 negative regulation of cellular protein metabolic process 0.925954 70644 vitamin D response element binding 0.925903 60260 regulation of transcription initiation from RNA polymerase II promoter 0.925898 4661 protein geranylgeranyltransferase activity 0.925876 18224 protein geranylgeranyltransferase activity 0.925876 9077 histidine family amino acid catabolic process 0.925865 6548 histidine catabolic process 0.925865 70584 mitochondrion morphogenesis 0.925787 32119 sequestering of zinc ion 0.925781 30488 tRNA methylation 0.925774 1300 chronological cell aging 0.925753 31644 regulation of neurological system process 0.925687 33791 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity 0.925684 1836 release of cytochrome c from mitochondria 0.925649 51668 localization within membrane 0.925638 5847 mRNA cleavage and polyadenylation specificity factor complex 0.925636 42733 embryonic digit morphogenesis 0.925602 15205 nucleobase transmembrane transporter activity 0.925594 30252 growth hormone secretion 0.925581 19748 secondary metabolic process 0.925572 5017 platelet-derived growth factor receptor activity 0.925565 4607 phosphatidylcholine-sterol O-acyltransferase activity 0.925560 51184 cofactor transporter activity 0.925552 51567 histone H3-K9 methylation 0.925536 34067 protein localization in Golgi apparatus 0.925512 5945 6-phosphofructokinase complex 0.925500 3872 6-phosphofructokinase activity 0.925500 33555 multicellular organismal response to stress 0.925498 9440 cyanate catabolic process 0.925488 9439 cyanate metabolic process 0.925488 42439 ethanolamine and derivative metabolic process 0.925464 51882 mitochondrial depolarization 0.925443 9629 response to gravity 0.925404 9612 response to mechanical stimulus 0.925403 8386 cholesterol monooxygenase (side-chain-cleaving) activity 0.925395 30158 protein xylosyltransferase activity 0.925391 35252 UDP-xylosyltransferase activity 0.925391 42285 xylosyltransferase activity 0.925391 30149 sphingolipid catabolic process 0.925380 46466 membrane lipid catabolic process 0.925380 4757 sepiapterin reductase activity 0.925346 5071 transmembrane receptor protein serine/threonine kinase signaling protein activity 0.925343 46209 nitric oxide metabolic process 0.925324 3908 methylated-DNA-[protein]-cysteine S-methyltransferase activity 0.925250 19883 antigen processing and presentation of endogenous antigen 0.925207 16188 synaptic vesicle maturation 0.925197 16426 tRNA (adenine)-methyltransferase activity 0.925174 16429 tRNA (adenine-N1-)-methyltransferase activity 0.925174 1909 leukocyte mediated cytotoxicity 0.925152 3884 D-amino-acid oxidase activity 0.925150 16803 ether hydrolase activity 0.925143 45113 regulation of integrin biosynthetic process 0.925130 45807 positive regulation of endocytosis 0.925104 16428 tRNA (cytosine-5-)-methyltransferase activity 0.925077 16427 tRNA (cytosine)-methyltransferase activity 0.925077 9063 cellular amino acid catabolic process 0.925064 1541 ovarian follicle development 0.925041 48066 pigmentation during development 0.924990 60761 negative regulation of response to cytokine stimulus 0.924960 51303 establishment of chromosome localization 0.924943 9642 response to light intensity 0.924912 42990 regulation of transcription factor import into nucleus 0.924903 16971 flavin-linked sulfhydryl oxidase activity 0.924864 4051 arachidonate 5-lipoxygenase activity 0.924815 6940 regulation of smooth muscle contraction 0.924796 4305 ethanolamine kinase activity 0.924792 51393 alpha-actinin binding 0.924760 5968 Rab-protein geranylgeranyltransferase complex 0.924715 33365 protein localization in organelle 0.924711 60562 epithelial tube morphogenesis 0.924690 1658 branching involved in ureteric bud morphogenesis 0.924690 7296 vitellogenesis 0.924670 3910 DNA ligase (ATP) activity 0.924631 3909 DNA ligase activity 0.924631 6575 cellular amino acid derivative metabolic process 0.924580 32879 regulation of localization 0.924576 7527 adult somatic muscle development 0.924526 46697 decidualization 0.924524 9069 serine family amino acid metabolic process 0.924492 34097 response to cytokine stimulus 0.924492 30329 prenylcysteine metabolic process 0.924474 30328 prenylcysteine catabolic process 0.924474 4937 alpha1-adrenergic receptor activity 0.924470 16445 somatic diversification of immunoglobulins 0.924448 18346 protein amino acid prenylation 0.924443 43403 skeletal muscle tissue regeneration 0.924430 8206 bile acid metabolic process 0.924381 1891 phagocytic cup 0.924357 31575 G1/S transition checkpoint 0.924341 48732 gland development 0.924336 4482 mRNA (guanine-N7-)-methyltransferase activity 0.924284 16280 aging 0.924266 6591 ornithine metabolic process 0.924261 51969 regulation of transmission of nerve impulse 0.924199 32052 bile acid binding 0.924192 8395 steroid hydroxylase activity 0.924188 42491 auditory receptor cell differentiation 0.924161 6942 regulation of striated muscle contraction 0.924155 33858 N-acetylgalactosamine kinase activity 0.924139 9894 regulation of catabolic process 0.924137 4528 phosphodiesterase I activity 0.924128 9954 proximal/distal pattern formation 0.924114 60402 calcium ion transport into cytosol 0.924112 45069 regulation of viral genome replication 0.924085 30098 lymphocyte differentiation 0.924075 46839 phospholipid dephosphorylation 0.924063 4473 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity 0.924039 31334 positive regulation of protein complex assembly 0.923998 51043 regulation of membrane protein ectodomain proteolysis 0.923965 4085 butyryl-CoA dehydrogenase activity 0.923946 9054 electron carrier activity 0.923942 9053 electron carrier activity 0.923942 45155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity 0.923942 48485 sympathetic nervous system development 0.923923 6551 leucine metabolic process 0.923923 5294 neutral L-amino acid secondary active transmembrane transporter activity 0.923907 21954 central nervous system neuron development 0.923869 1895 retina homeostasis 0.923864 4619 phosphoglycerate mutase activity 0.923863 4083 2,3-bisphospho-D-glycerate 2-phosphohydrolase activity 0.923863 4082 bisphosphoglycerate mutase activity 0.923863 10890 positive regulation of sequestering of triglyceride 0.923858 51262 protein tetramerization 0.923852 4736 pyruvate carboxylase activity 0.923850 15822 ornithine transport 0.923749 66 mitochondrial ornithine transport 0.923749 64 L-ornithine transmembrane transporter activity 0.923749 42098 T cell proliferation 0.923734 42554 superoxide anion generation 0.923731 48663 neuron fate commitment 0.923730 48499 synaptic vesicle membrane organization 0.923705 21915 neural tube development 0.923696 30997 regulation of centriole-centriole cohesion 0.923677 48388 endosomal lumen acidification 0.923629 35295 tube development 0.923555 42168 heme metabolic process 0.923536 15851 nucleobase transport 0.923429 10469 regulation of receptor activity 0.923426 45111 intermediate filament cytoskeleton 0.923387 8329 pattern recognition receptor activity 0.923377 5135 interleukin-3 receptor binding 0.923367 5159 insulin-like growth factor receptor binding 0.923326 4679 AMP-activated protein kinase activity 0.923318 9084 glutamine family amino acid biosynthetic process 0.923279 42107 cytokine metabolic process 0.923234 16882 cyclo-ligase activity 0.923230 40015 negative regulation of multicellular organism growth 0.923082 6541 glutamine metabolic process 0.923067 50853 B cell receptor signaling pathway 0.923027 55078 sodium ion homeostasis 0.922981 51146 striated muscle cell differentiation 0.922964 17057 6-phosphogluconolactonase activity 0.922928 65002 intracellular protein transmembrane transport 0.922888 51382 kinetochore assembly 0.922860 2200 somatic diversification of immune receptors 0.922801 4092 carnitine O-acetyltransferase activity 0.922787 1705 ectoderm formation 0.922735 33566 gamma-tubulin complex localization 0.922691 55061 di-, tri-valent inorganic anion homeostasis 0.922675 55062 phosphate ion homeostasis 0.922675 15824 proline transport 0.922667 1676 long-chain fatty acid metabolic process 0.922664 8328 ionotropic glutamate receptor complex 0.922650 48562 embryonic organ morphogenesis 0.922611 32440 2-alkenal reductase activity 0.922594 48630 skeletal muscle tissue growth 0.922590 51329 interphase of mitotic cell cycle 0.922546 16713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 0.922521 5960 glycine cleavage complex 0.922497 48102 autophagic cell death 0.922494 4956 prostaglandin D receptor activity 0.922470 1785 prostaglandin J receptor activity 0.922470 70727 cellular macromolecule localization 0.922423 48199 vesicle targeting, to, from or within Golgi 0.922421 17130 poly(C) RNA binding 0.922401 42978 ornithine decarboxylase activator activity 0.922377 42398 cellular amino acid derivative biosynthetic process 0.922347 30010 establishment of cell polarity 0.922344 303 response to superoxide 0.922272 177 cytoplasmic exosome (RNase complex) 0.922256 50768 negative regulation of neurogenesis 0.922254 3717 RNA polymerase II transcription termination factor activity 0.922208 47006 20-alpha-hydroxysteroid dehydrogenase activity 0.922204 48599 oocyte development 0.922184 6939 smooth muscle contraction 0.922142 1822 kidney development 0.922139 4633 phosphopantothenoylcysteine decarboxylase activity 0.922111 6562 proline catabolic process 0.922088 18342 protein prenylation 0.922082 9032 thymidine phosphorylase activity 0.922063 31118 rRNA pseudouridine synthesis 0.922015 70576 vitamin D 24-hydroxylase activity 0.922011 50905 neuromuscular process 0.921987 8106 alcohol dehydrogenase (NADP+) activity 0.921987 60136 embryonic process involved in female pregnancy 0.921979 33981 D-dopachrome decarboxylase activity 0.921966 45806 negative regulation of endocytosis 0.921893 19763 immunoglobulin receptor activity 0.921878 1837 epithelial to mesenchymal transition 0.921852 15038 glutathione disulfide oxidoreductase activity 0.921846 15037 peptide disulfide oxidoreductase activity 0.921846 50974 detection of mechanical stimulus involved in sensory perception 0.921818 17075 syntaxin-1 binding 0.921782 46330 positive regulation of JNK cascade 0.921756 35299 inositol pentakisphosphate 2-kinase activity 0.921725 16175 superoxide-generating NADPH oxidase activity 0.921714 4776 succinate-CoA ligase (GDP-forming) activity 0.921697 70412 R-SMAD binding 0.921696 46504 glycerol ether biosynthetic process 0.921626 8279 cohesin complex 0.921605 43236 laminin binding 0.921603 213 tRNA-intron endonuclease activity 0.921504 35239 tube morphogenesis 0.921502 51547 regulation of keratinocyte migration 0.921460 51549 positive regulation of keratinocyte migration 0.921460 45596 negative regulation of cell differentiation 0.921427 10721 negative regulation of cell development 0.921394 21559 trigeminal nerve development 0.921387 16316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity 0.921335 34597 phosphatidyl-inositol-4,5-bisphosphate 4-phosphatase activity 0.921335 34596 phosphoinositide 4-phosphatase activity 0.921335 1880 Mullerian duct regression 0.921331 47631 ADP-ribose diphosphatase activity 0.921327 19144 ADP-sugar diphosphatase activity 0.921327 21984 adenohypophysis development 0.921279 6564 L-serine biosynthetic process 0.921250 46525 xylosylprotein 4-beta-galactosyltransferase activity 0.921242 42609 CD4 receptor binding 0.921214 99 sulfur amino acid transmembrane transporter activity 0.921207 4138 deoxyguanosine kinase activity 0.921194 70288 ferritin complex 0.921166 8043 intracellular ferritin complex 0.921166 43208 glycosphingolipid binding 0.921142 8065 establishment of blood-nerve barrier 0.921117 21591 ventricular system development 0.921049 32090 Pyrin domain binding 0.921045 45749 negative regulation of S phase of mitotic cell cycle 0.920981 51546 keratinocyte migration 0.920977 33500 carbohydrate homeostasis 0.920924 42593 glucose homeostasis 0.920924 4558 alpha-glucosidase activity 0.920917 8061 chitin binding 0.920900 8539 proteasome inhibitor activity 0.920876 51705 behavioral interaction between organisms 0.920871 46148 pigment biosynthetic process 0.920867 90047 positive regulation of transcription regulator activity 0.920838 51091 positive regulation of transcription factor activity 0.920838 33540 fatty acid beta-oxidation using acyl-CoA oxidase 0.920812 4055 argininosuccinate synthase activity 0.920759 21846 cell proliferation in forebrain 0.920707 5416 cation:amino acid symporter activity 0.920690 126 transcription factor TFIIIB complex 0.920663 48545 response to steroid hormone stimulus 0.920655 9147 pyrimidine nucleoside triphosphate metabolic process 0.920588 16549 tRNA modification 0.920585 30612 arsenate reductase (thioredoxin) activity 0.920566 45682 regulation of epidermis development 0.920522 9223 pyrimidine deoxyribonucleotide catabolic process 0.920502 33882 choloyl-CoA hydrolase activity 0.920421 4074 biliverdin reductase activity 0.920417 4861 cyclin-dependent protein kinase inhibitor activity 0.920406 3751 cyclin-dependent protein kinase regulator activity 0.920406 3752 cyclin-dependent protein kinase regulator activity 0.920406 3753 cyclin-dependent protein kinase regulator activity 0.920406 31109 microtubule polymerization or depolymerization 0.920397 47620 acylglycerol kinase activity 0.920373 50327 testosterone 17-beta-dehydrogenase activity 0.920349 50673 epithelial cell proliferation 0.920337 45130 keratan sulfotransferase activity 0.920324 42542 response to hydrogen peroxide 0.920296 33865 nucleoside bisphosphate metabolic process 0.920290 2768 immune response-regulating cell surface receptor signaling pathway 0.920268 48169 regulation of long-term neuronal synaptic plasticity 0.920253 1894 tissue homeostasis 0.920244 42391 regulation of membrane potential 0.920232 45598 regulation of fat cell differentiation 0.920230 35020 regulation of Rac protein signal transduction 0.920212 5785 signal recognition particle receptor complex 0.920200 4301 epoxide hydrolase activity 0.920192 15204 urea transmembrane transporter activity 0.920152 42887 amide transporter activity 0.920152 40016 embryonic cleavage 0.920152 2456 T cell mediated immunity 0.920140 51092 positive regulation of NF-kappaB transcription factor activity 0.920133 7613 memory 0.920109 32311 angiogenin-PRI complex 0.920103 5828 kinetochore microtubule 0.920087 14909 smooth muscle cell migration 0.920083 42149 cellular response to glucose starvation 0.920047 52126 movement in host environment 0.920018 52192 movement in environment of other organism during symbiotic interaction 0.920018 30260 entry into host cell 0.920018 44409 entry into host 0.920018 46718 entry of virus into host cell 0.920018 51828 entry into other organism during symbiotic interaction 0.920018 51806 entry into cell of other organism during symbiotic interaction 0.920018 46935 1-phosphatidylinositol-3-kinase regulator activity 0.920007 35022 positive regulation of Rac protein signal transduction 0.919999 48257 3'-flap endonuclease activity 0.919934 51053 negative regulation of DNA metabolic process 0.919884 60401 cytosolic calcium ion transport 0.919884 5176 ErbB-2 class receptor binding 0.919882 7258 JUN phosphorylation 0.919842 30643 cellular phosphate ion homeostasis 0.919798 30319 cellular di-, tri-valent inorganic anion homeostasis 0.919798 51239 regulation of multicellular organismal process 0.919723 1516 prostaglandin biosynthetic process 0.919719 46457 prostanoid biosynthetic process 0.919719 15742 alpha-ketoglutarate transport 0.919648 60325 face morphogenesis 0.919597 22008 neurogenesis 0.919550 48583 regulation of response to stimulus 0.919523 70120 ciliary neurotrophic factor-mediated signaling pathway 0.919449 15375 glycine:sodium symporter activity 0.919427 8649 rRNA methyltransferase activity 0.919415 16433 rRNA (adenine) methyltransferase activity 0.919415 179 rRNA (adenine-N6,N6-)-dimethyltransferase activity 0.919415 4113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity 0.919407 9156 ribonucleoside monophosphate biosynthetic process 0.919368 9161 ribonucleoside monophosphate metabolic process 0.919368 45347 negative regulation of MHC class II biosynthetic process 0.919347 30171 voltage-gated proton channel activity 0.919331 60491 regulation of cell projection assembly 0.919316 30140 trans-Golgi network transport vesicle 0.919313 6393 termination of mitochondrial transcription 0.919310 6649 phospholipid transfer to membrane 0.919262 50290 sphingomyelin phosphodiesterase D activity 0.919214 51646 mitochondrion localization 0.919178 6278 RNA-dependent DNA replication 0.919150 43434 response to peptide hormone stimulus 0.919137 21858 GABAergic neuron differentiation in the basal ganglia 0.919117 32314 regulation of Rac GTPase activity 0.919109 43490 malate-aspartate shuttle 0.919089 34641 cellular nitrogen compound metabolic process 0.919082 30728 ovulation 0.919054 6545 glycine biosynthetic process 0.919045 9127 purine nucleoside monophosphate biosynthetic process 0.919026 9126 purine nucleoside monophosphate metabolic process 0.919026 9168 purine ribonucleoside monophosphate biosynthetic process 0.919026 9167 purine ribonucleoside monophosphate metabolic process 0.919026 4904 interferon receptor activity 0.919021 19961 interferon binding 0.919021 22409 positive regulation of cell-cell adhesion 0.919011 31315 extrinsic to mitochondrial outer membrane 0.918972 35024 negative regulation of Rho protein signal transduction 0.918937 48676 axon extension involved in development 0.918924 1534 radial spoke 0.918924 8781 N-acylneuraminate cytidylyltransferase activity 0.918920 51093 negative regulation of developmental process 0.918885 16645 oxidoreductase activity, acting on the CH-NH group of donors 0.918811 42891 antibiotic transport 0.918808 45171 intercellular bridge 0.918779 46470 phosphatidylcholine metabolic process 0.918745 30539 male genitalia development 0.918729 43515 kinetochore binding 0.918695 16054 organic acid catabolic process 0.918694 46395 carboxylic acid catabolic process 0.918694 8331 high voltage-gated calcium channel activity 0.918683 60249 anatomical structure homeostasis 0.918682 2011 morphogenesis of an epithelial sheet 0.918677 50885 neuromuscular process controlling balance 0.918676 781 chromosome, telomeric region 0.918643 18195 peptidyl-arginine modification 0.918630 45663 positive regulation of myoblast differentiation 0.918610 51701 interaction with host 0.918561 34637 cellular carbohydrate biosynthetic process 0.918559 30851 granulocyte differentiation 0.918546 60088 auditory receptor cell stereocilium organization 0.918534 8344 adult locomotory behavior 0.918507 16074 snoRNA metabolic process 0.918490 32364 oxygen homeostasis 0.918445 46685 response to arsenic 0.918445 50804 regulation of synaptic transmission 0.918406 4441 inositol-1,4-bisphosphate 1-phosphatase activity 0.918393 89 mitotic metaphase 0.918369 48753 pigment granule organization 0.918367 6809 nitric oxide biosynthetic process 0.918308 35051 cardiac cell differentiation 0.918279 31995 insulin-like growth factor II binding 0.918244 8053 mitochondrial fusion 0.918176 35014 phosphoinositide 3-kinase regulator activity 0.918176 43486 histone exchange 0.918164 51052 regulation of DNA metabolic process 0.918162 50664 oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor 0.918152 2495 antigen processing and presentation of peptide antigen via MHC class II 0.918107 2478 antigen processing and presentation of exogenous peptide antigen 0.918107 19886 antigen processing and presentation of exogenous peptide antigen via MHC class II 0.918107 17064 fatty acid amide hydrolase activity 0.918103 45919 positive regulation of cytolysis 0.918099 43176 amine binding 0.918093 46364 monosaccharide biosynthetic process 0.918092 21675 nerve development 0.918085 15798 myo-inositol transport 0.918075 47280 nicotinamide phosphoribosyltransferase activity 0.918055 6702 androgen biosynthetic process 0.918015 4617 phosphoglycerate dehydrogenase activity 0.918007 6801 superoxide metabolic process 0.917990 51187 cofactor catabolic process 0.917953 50528 acyloxyacyl hydrolase activity 0.917910 51919 positive regulation of fibrinolysis 0.917898 30504 inorganic diphosphate transmembrane transporter activity 0.917862 19707 protein-cysteine S-acyltransferase activity 0.917858 19706 protein-cysteine S-palmitoleyltransferase activity 0.917858 6543 glutamine catabolic process 0.917814 30296 protein tyrosine kinase activator activity 0.917774 16929 SUMO-specific protease activity 0.917765 4935 adrenoceptor activity 0.917610 15183 L-aspartate transmembrane transporter activity 0.917564 8642 small protein activating enzyme activity 0.917556 4304 estrone sulfotransferase activity 0.917524 35254 glutamate receptor binding 0.917520 9132 nucleoside diphosphate metabolic process 0.917508 733 DNA strand renaturation 0.917496 35050 embryonic heart tube development 0.917381 70625 zymogen granule exocytosis 0.917282 55007 cardiac muscle cell differentiation 0.917188 30377 U-plasminogen activator receptor activity 0.917186 16149 translation release factor activity, codon specific 0.917129 3749 translation release factor activity 0.917129 3748 translation release factor activity 0.917129 16783 sulfurtransferase activity 0.917120 2521 leukocyte differentiation 0.917111 51099 positive regulation of binding 0.917105 6275 regulation of DNA replication 0.917100 55002 striated muscle cell development 0.917089 35162 embryonic hemopoiesis 0.917029 48146 positive regulation of fibroblast proliferation 0.917011 3720 telomerase activity 0.916968 6303 double-strand break repair via nonhomologous end joining 0.916950 726 non-recombinational repair 0.916950 9 alpha-1,6-mannosyltransferase activity 0.916944 19794 nonprotein amino acid metabolic process 0.916913 50473 arachidonate 15-lipoxygenase activity 0.916892 6590 thyroid hormone generation 0.916884 4918 interleukin-8 receptor activity 0.916868 4686 elongation factor-2 kinase activity 0.916848 51607 defense response to virus 0.916824 3918 DNA topoisomerase (ATP-hydrolyzing) activity 0.916812 40012 regulation of locomotion 0.916789 2429 immune response-activating cell surface receptor signaling pathway 0.916759 48873 homeostasis of number of cells within a tissue 0.916748 30507 spectrin binding 0.916739 51183 vitamin transporter activity 0.916725 2483 antigen processing and presentation of endogenous peptide antigen 0.916707 19885 antigen processing and presentation of endogenous peptide antigen via MHC class I 0.916707 4856 xylulokinase activity 0.916703 48754 branching morphogenesis of a tube 0.916687 8242 omega peptidase activity 0.916663 45092 interleukin-18 receptor complex 0.916655 30431 sleep 0.916648 3007 heart morphogenesis 0.916646 42596 fear response 0.916633 8637 apoptotic mitochondrial changes 0.916621 32228 regulation of synaptic transmission, GABAergic 0.916589 33014 tetrapyrrole biosynthetic process 0.916567 6779 porphyrin biosynthetic process 0.916567 3955 NAD(P)H dehydrogenase (quinone) activity 0.916558 45839 negative regulation of mitosis 0.916536 51784 negative regulation of nuclear division 0.916536 1936 regulation of endothelial cell proliferation 0.916530 42723 thiamin and derivative metabolic process 0.916494 48408 epidermal growth factor binding 0.916413 6584 catecholamine metabolic process 0.916396 9712 catechol metabolic process 0.916396 34311 diol metabolic process 0.916396 6733 oxidoreduction coenzyme metabolic process 0.916378 30913 paranodal junction assembly 0.916365 7612 learning 0.916353 32027 myosin light chain binding 0.916313 30513 positive regulation of BMP signaling pathway 0.916244 16781 phosphotransferase activity, paired acceptors 0.916240 4756 selenide, water dikinase activity 0.916240 3692 left-handed Z-DNA binding 0.916220 30278 regulation of ossification 0.916168 156 two-component response regulator activity 0.916168 6448 regulation of translational elongation 0.916161 3938 IMP dehydrogenase activity 0.916119 15910 peroxisomal long-chain fatty acid import 0.916027 45475 locomotor rhythm 0.916019 30854 positive regulation of granulocyte differentiation 0.915979 70997 neuron death 0.915920 51402 neuron apoptosis 0.915920 34453 microtubule anchoring 0.915918 6687 glycosphingolipid metabolic process 0.915896 46928 regulation of neurotransmitter secretion 0.915870 4508 steroid 17-alpha-monooxygenase activity 0.915834 46835 carbohydrate phosphorylation 0.915821 51181 cofactor transport 0.915800 40013 negative regulation of locomotion 0.915793 45595 regulation of cell differentiation 0.915786 46051 UTP metabolic process 0.915783 4550 nucleoside diphosphate kinase activity 0.915783 6183 GTP biosynthetic process 0.915783 6228 UTP biosynthetic process 0.915783 45123 cellular extravasation 0.915757 9411 response to UV 0.915726 32273 positive regulation of protein polymerization 0.915709 48145 regulation of fibroblast proliferation 0.915698 4406 histone acetyltransferase activity 0.915604 2682 regulation of immune system process 0.915596 30239 myofibril assembly 0.915594 9268 response to pH 0.915561 15184 L-cystine transmembrane transporter activity 0.915557 16266 O-glycan processing 0.915540 46463 acylglycerol biosynthetic process 0.915531 46460 neutral lipid biosynthetic process 0.915531 30868 smooth endoplasmic reticulum membrane 0.915516 51098 regulation of binding 0.915434 34504 protein localization in nucleus 0.915391 60052 neurofilament cytoskeleton organization 0.915322 16571 histone methylation 0.915322 45946 positive regulation of translation 0.915304 4694 eukaryotic translation initiation factor 2alpha kinase activity 0.915278 21884 forebrain neuron development 0.915257 42 protein targeting to Golgi 0.915202 301 retrograde transport, vesicle recycling within Golgi 0.915202 51591 response to cAMP 0.915196 48010 vascular endothelial growth factor receptor signaling pathway 0.915146 46036 CTP metabolic process 0.915125 9148 pyrimidine nucleoside triphosphate biosynthetic process 0.915125 9208 pyrimidine ribonucleoside triphosphate metabolic process 0.915125 9209 pyrimidine ribonucleoside triphosphate biosynthetic process 0.915125 6241 CTP biosynthetic process 0.915125 21680 cerebellar Purkinje cell layer development 0.915117 4163 diphosphomevalonate decarboxylase activity 0.915109 43089 positive regulation of Cdc42 GTPase activity 0.915069 60135 maternal process involved in female pregnancy 0.915057 6721 terpenoid metabolic process 0.915036 15993 molecular hydrogen transport 0.914912 50512 lactosylceramide 4-alpha-galactosyltransferase activity 0.914868 51310 metaphase plate congression 0.914836 4398 histidine decarboxylase activity 0.914820 247 C-8 sterol isomerase activity 0.914795 8343 adult feeding behavior 0.914767 48535 lymph node development 0.914759 1967 suckling behavior 0.914755 4373 glycogen (starch) synthase activity 0.914731 30214 hyaluronan catabolic process 0.914675 16056 rhodopsin mediated signaling pathway 0.914650 42030 ATPase inhibitor activity 0.914647 43560 insulin receptor substrate binding 0.914622 5927 muscle tendon junction 0.914598 8040 axon guidance 0.914583 8480 sarcosine dehydrogenase activity 0.914578 48584 positive regulation of response to stimulus 0.914561 43388 positive regulation of DNA binding 0.914557 71553 pyrimidinergic nucleotide receptor activity, G-protein coupled 0.914554 15065 uridine nucleotide receptor activity 0.914554 1763 morphogenesis of a branching structure 0.914530 34189 very-low-density lipoprotein binding 0.914530 30229 very-low-density lipoprotein receptor activity 0.914530 17183 peptidyl-diphthamide biosynthetic process from peptidyl-histidine 0.914502 17182 peptidyl-diphthamide metabolic process 0.914502 31125 rRNA 3'-end processing 0.914482 6475 internal protein amino acid acetylation 0.914429 4657 proline dehydrogenase activity 0.914405 46523 S-methyl-5-thioribose-1-phosphate isomerase activity 0.914385 4816 asparagine-tRNA ligase activity 0.914381 6421 asparaginyl-tRNA aminoacylation 0.914381 51270 regulation of cellular component movement 0.914361 6732 coenzyme metabolic process 0.914353 16715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen 0.914291 34481 chondroitin sulfotransferase activity 0.914214 138 Golgi trans cisterna 0.914200 60070 Wnt receptor signaling pathway through beta-catenin 0.914191 8184 glycogen phosphorylase activity 0.914151 45001 nucleotide-excision repair 0.914139 6283 transcription-coupled nucleotide-excision repair 0.914139 48635 negative regulation of muscle organ development 0.914139 4728 receptor signaling protein tyrosine phosphatase activity 0.914095 31082 BLOC complex 0.914023 31083 BLOC-1 complex 0.914023 19863 IgE binding 0.914001 42602 flavin reductase activity 0.913999 15925 galactosidase activity 0.913990 15012 heparan sulfate proteoglycan biosynthetic process 0.913974 16406 carnitine O-acyltransferase activity 0.913946 42100 B cell proliferation 0.913879 30917 midbrain-hindbrain boundary development 0.913806 4447 iodide peroxidase activity 0.913757 51220 cytoplasmic sequestering of protein 0.913733 4490 methylglutaconyl-CoA hydratase activity 0.913709 31638 zymogen activation 0.913686 16174 NAD(P)H oxidase activity 0.913634 9650 UV protection 0.913617 2089 lens morphogenesis in camera-type eye 0.913584 51129 negative regulation of cellular component organization 0.913576 32444 activin responsive factor complex 0.913572 2347 response to tumor cell 0.913547 48008 platelet-derived growth factor receptor signaling pathway 0.913538 7100 mitotic centrosome separation 0.913512 48589 developmental growth 0.913501 42110 T cell activation 0.913427 1935 endothelial cell proliferation 0.913334 70309 lens fiber cell morphogenesis 0.913330 30382 sperm mitochondrion organization 0.913323 104 succinate dehydrogenase activity 0.913238 26 alpha-1,2-mannosyltransferase activity 0.913226 43121 neurotrophin binding 0.913203 47496 vesicle transport along microtubule 0.913189 10621 negative regulation of transcription by transcription factor localization 0.913178 8294 calcium- and calmodulin-responsive adenylate cyclase activity 0.913153 33327 Leydig cell differentiation 0.913150 46823 negative regulation of nucleocytoplasmic transport 0.913145 16235 aggresome 0.913105 1887 selenium metabolic process 0.913101 3944 N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity 0.913033 4348 glucosylceramidase activity 0.912980 30336 negative regulation of cell migration 0.912960 42982 amyloid precursor protein metabolic process 0.912960 50698 proteoglycan sulfotransferase activity 0.912956 6213 pyrimidine nucleoside metabolic process 0.912949 46686 response to cadmium ion 0.912948 10720 positive regulation of cell development 0.912917 15175 neutral amino acid transmembrane transporter activity 0.912894 31264 death-inducing signaling complex 0.912891 45737 positive regulation of cyclin-dependent protein kinase activity 0.912851 8349 MAP kinase kinase kinase kinase activity 0.912840 4676 3-phosphoinositide-dependent protein kinase activity 0.912792 16561 protein import into peroxisome matrix, translocation 0.912743 15942 formate metabolic process 0.912739 48699 generation of neurons 0.912736 8318 protein prenyltransferase activity 0.912714 31957 very-long-chain-fatty-acid-CoA ligase activity 0.912695 31102 neuron projection regeneration 0.912687 31103 axon regeneration 0.912687 31295 T cell costimulation 0.912670 31294 lymphocyte costimulation 0.912670 70524 11-beta-hydroxysteroid dehydrogenase (NADP+) activity 0.912647 6783 heme biosynthetic process 0.912629 70491 transcription repressor binding 0.912628 6596 polyamine biosynthetic process 0.912605 70208 protein heterotrimerization 0.912570 60170 cilium membrane 0.912563 51271 negative regulation of cellular component movement 0.912543 305 response to oxygen radical 0.912527 8278 cohesin complex 0.912465 10565 regulation of cellular ketone metabolic process 0.912457 46655 folic acid metabolic process 0.912425 2209 behavioral defense response 0.912424 1663 fear response 0.912424 1662 behavioral fear response 0.912424 15988 energy coupled proton transport, against electrochemical gradient 0.912424 15991 ATP hydrolysis coupled proton transport 0.912424 8644 carbohydrate transport 0.912403 6861 carbohydrate transport 0.912403 46426 negative regulation of JAK-STAT cascade 0.912384 16899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor 0.912377 3973 (S)-2-hydroxy-acid oxidase activity 0.912377 18931 naphthalene metabolic process 0.912357 51345 positive regulation of hydrolase activity 0.912322 42637 catagen 0.912309 5131 growth hormone receptor binding 0.912282 45132 meiotic chromosome segregation 0.912280 30892 mitotic cohesin complex 0.912280 31213 RSF complex 0.912232 30273 melanin-concentrating hormone receptor activity 0.912212 34332 adherens junction organization 0.912208 2684 positive regulation of immune system process 0.912188 6775 fat-soluble vitamin metabolic process 0.912135 55067 monovalent inorganic cation homeostasis 0.912131 50776 regulation of immune response 0.912124 32449 CBM complex 0.912027 5069 transmembrane receptor protein tyrosine kinase docking protein activity 0.912027 31399 regulation of protein modification process 0.912024 12510 trans-Golgi network transport vesicle membrane 0.912019 50679 positive regulation of epithelial cell proliferation 0.912005 60191 regulation of lipase activity 0.911997 32465 regulation of cytokinesis 0.911973 42335 cuticle development 0.911966 930 gamma-tubulin complex 0.911928 42226 interleukin-6 biosynthetic process 0.911918 10 trans-hexaprenyltranstransferase activity 0.911870 8217 regulation of blood pressure 0.911843 33961 cis-stilbene-oxide hydrolase activity 0.911826 6595 polyamine metabolic process 0.911814 30867 rough endoplasmic reticulum membrane 0.911777 4914 interleukin-5 receptor activity 0.911749 19980 interleukin-5 binding 0.911749 4769 steroid delta-isomerase activity 0.911737 1560 regulation of cell growth by extracellular stimulus 0.911725 15232 heme transporter activity 0.911725 72 M phase specific microtubule process 0.911725 6002 fructose 6-phosphate metabolic process 0.911704 5381 iron ion transmembrane transporter activity 0.911587 4347 glucose-6-phosphate isomerase activity 0.911536 50294 steroid sulfotransferase activity 0.911508 737 DNA catabolic process, endonucleolytic 0.911496 42992 negative regulation of transcription factor import into nucleus 0.911485 32983 kainate selective glutamate receptor complex 0.911391 45059 positive thymic T cell selection 0.911354 7270 nerve-nerve synaptic transmission 0.911354 9374 biotin binding 0.911306 4972 N-methyl-D-aspartate selective glutamate receptor activity 0.911281 43422 protein kinase B binding 0.911258 30150 protein import into mitochondrial matrix 0.911238 51373 FATZ binding 0.911194 51186 cofactor metabolic process 0.911185 16646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 0.911181 5964 phosphorylase kinase complex 0.911173 45229 external encapsulating structure organization 0.911170 43163 cell envelope organization 0.911170 6000 fructose metabolic process 0.911087 45652 regulation of megakaryocyte differentiation 0.911084 42743 hydrogen peroxide metabolic process 0.911062 32387 negative regulation of intracellular transport 0.911037 4912 interleukin-3 receptor activity 0.911025 19978 interleukin-3 binding 0.911025 4019 adenylosuccinate synthase activity 0.911001 16413 O-acetyltransferase activity 0.910997 4666 prostaglandin-endoperoxide synthase activity 0.910976 34754 cellular hormone metabolic process 0.910907 6663 platelet activating factor biosynthetic process 0.910900 33615 mitochondrial proton-transporting ATP synthase complex assembly 0.910880 5019 platelet-derived growth factor beta-receptor activity 0.910856 45351 type I interferon biosynthetic process 0.910851 47016 cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity 0.910812 19870 potassium channel inhibitor activity 0.910807 30193 regulation of blood coagulation 0.910796 7595 lactation 0.910787 16941 natriuretic peptide receptor activity 0.910763 31256 leading edge membrane 0.910756 10741 negative regulation of protein kinase cascade 0.910729 32007 negative regulation of TOR signaling pathway 0.910690 1932 regulation of protein amino acid phosphorylation 0.910668 42287 MHC protein binding 0.910663 19319 hexose biosynthetic process 0.910662 45261 proton-transporting ATP synthase complex, catalytic core F(1) 0.910634 3715 transcription termination factor activity 0.910618 4951 cholecystokinin receptor activity 0.910590 802 transverse filament 0.910590 51786 all-trans-retinol 13,14-reductase activity 0.910570 48284 organelle fusion 0.910559 45739 positive regulation of DNA repair 0.910559 4063 aryldialkylphosphatase activity 0.910542 5185 neurohypophyseal hormone activity 0.910542 42177 negative regulation of protein catabolic process 0.910513 48729 tissue morphogenesis 0.910496 42698 ovulation cycle 0.910494 18958 phenol metabolic process 0.910479 42360 vitamin E metabolic process 0.910425 45647 negative regulation of erythrocyte differentiation 0.910360 4310 farnesyl-diphosphate farnesyltransferase activity 0.910329 32964 collagen biosynthetic process 0.910328 51298 centrosome duplication 0.910304 42477 odontogenesis 0.910299 42475 odontogenesis of dentine-containing tooth 0.910299 9109 coenzyme catabolic process 0.910274 43653 mitochondrial fragmentation during apoptosis 0.910252 45646 regulation of erythrocyte differentiation 0.910225 6949 syncytium formation 0.910196 7520 myoblast fusion 0.910196 768 syncytium formation by plasma membrane fusion 0.910196 19428 allantoin biosynthetic process 0.910184 4616 phosphogluconate dehydrogenase (decarboxylating) activity 0.910175 4365 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity 0.910155 8943 glyceraldehyde-3-phosphate dehydrogenase activity 0.910155 7402 ganglion mother cell fate determination 0.910136 16101 diterpenoid metabolic process 0.910126 1523 retinoid metabolic process 0.910126 6023 aminoglycan biosynthetic process 0.910124 42987 amyloid precursor protein catabolic process 0.910117 5148 prolactin receptor binding 0.910095 35093 spermatogenesis, exchange of chromosomal proteins 0.910087 35035 histone acetyltransferase binding 0.909953 43353 enucleate erythrocyte differentiation 0.909937 7159 leukocyte adhesion 0.909935 30321 transepithelial chloride transport 0.909852 30334 regulation of cell migration 0.909808 9019 tRNA (guanine-N1-)-methyltransferase activity 0.909798 7341 penetration of zona pellucida 0.909780 30299 intestinal cholesterol absorption 0.909776 10578 regulation of adenylate cyclase activity involved in G-protein signaling pathway 0.909748 10579 positive regulation of adenylate cyclase activity by G-protein signaling pathway 0.909748 7189 activation of adenylate cyclase activity by G-protein signaling pathway 0.909748 46339 diacylglycerol metabolic process 0.909736 43462 regulation of ATPase activity 0.909717 42564 NLS-dependent protein nuclear import complex 0.909701 1569 patterning of blood vessels 0.909698 32451 demethylase activity 0.909689 45055 regulated secretory pathway 0.909661 51238 sequestering of metal ion 0.909620 7431 salivary gland development 0.909552 4069 L-aspartate:2-oxoglutarate aminotransferase activity 0.909499 31405 lipoic acid binding 0.909452 34584 piRNA binding 0.909435 21904 dorsal/ventral neural tube patterning 0.909411 6893 Golgi to plasma membrane transport 0.909404 31545 peptidyl-proline 4-dioxygenase activity 0.909374 4656 procollagen-proline 4-dioxygenase activity 0.909374 22600 digestive system process 0.909363 4906 interferon-gamma receptor activity 0.909335 19964 interferon-gamma binding 0.909335 45861 negative regulation of proteolysis 0.909316 9083 branched chain family amino acid catabolic process 0.909188 6093 carbohydrate biosynthetic process 0.909183 7080 mitotic metaphase plate congression 0.909172 32886 regulation of microtubule-based process 0.909028 15616 DNA translocase activity 0.909025 16081 synaptic vesicle docking during exocytosis 0.909024 45324 late endosome to vacuole transport 0.908977 60284 regulation of cell development 0.908909 7271 synaptic transmission, cholinergic 0.908906 30878 thyroid gland development 0.908874 48675 axon extension 0.908833 70634 transepithelial ammonium transport 0.908823 31371 ubiquitin conjugating enzyme complex 0.908819 8148 negative transcription elongation factor activity 0.908803 35136 forelimb morphogenesis 0.908775 6800 oxygen and reactive oxygen species metabolic process 0.908772 9116 nucleoside metabolic process 0.908751 90046 regulation of transcription regulator activity 0.908748 51090 regulation of transcription factor activity 0.908748 43046 DNA methylation during gametogenesis 0.908730 44106 cellular amine metabolic process 0.908712 30183 B cell differentiation 0.908711 33280 response to vitamin D 0.908698 8579 JUN kinase phosphatase activity 0.908687 9253 peptidoglycan catabolic process 0.908661 9284 peptidoglycan metabolic process 0.908661 270 peptidoglycan metabolic process 0.908661 35088 establishment or maintenance of apical/basal cell polarity 0.908651 21512 spinal cord anterior/posterior patterning 0.908639 16153 urocanate hydratase activity 0.908542 9108 coenzyme biosynthetic process 0.908536 779 condensed chromosome, centromeric region 0.908488 10551 regulation of gene-specific transcription from RNA polymerase II promoter 0.908482 70633 transepithelial transport 0.908469 43193 positive regulation of gene-specific transcription 0.908420 244 assembly of spliceosomal tri-snRNP 0.908384 51879 Hsp90 protein binding 0.908372 7213 muscarinic acetylcholine receptor signaling pathway 0.908362 47273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity 0.908349 7569 cell aging 0.908328 5605 basal lamina 0.908243 7090 regulation of S phase of mitotic cell cycle 0.908219 47704 bile-salt sulfotransferase activity 0.908204 10165 response to X-ray 0.908200 32438 melanosome organization 0.908131 7638 mechanosensory behavior 0.908118 4990 oxytocin receptor activity 0.908108 8361 regulation of cell size 0.908088 19782 ISG15 activating enzyme activity 0.908059 48627 myoblast development 0.908055 7568 aging 0.908054 50892 intestinal absorption 0.908050 42060 wound healing 0.908046 50678 regulation of epithelial cell proliferation 0.908025 32868 response to insulin stimulus 0.908024 7176 regulation of epidermal growth factor receptor activity 0.907997 43517 positive regulation of DNA damage response, signal transduction by p53 class mediator 0.907963 42734 presynaptic membrane 0.907937 16531 copper chaperone activity 0.907922 5160 transforming growth factor beta receptor binding 0.907875 5175 CD27 receptor binding 0.907866 7263 nitric oxide mediated signal transduction 0.907825 8116 prostaglandin-I synthase activity 0.907818 6931 substrate-bound cell migration, cell attachment to substrate 0.907789 6024 glycosaminoglycan biosynthetic process 0.907789 16151 nickel ion binding 0.907761 6885 regulation of pH 0.907750 5595 collagen type XII 0.907721 50818 regulation of coagulation 0.907706 31304 intrinsic to mitochondrial inner membrane 0.907694 1918 farnesylated protein binding 0.907673 45884 regulation of survival gene product expression 0.907672 14731 spectrin-associated cytoskeleton 0.907645 2573 myeloid leukocyte differentiation 0.907640 43374 CD8-positive, alpha-beta T cell differentiation 0.907596 15807 L-amino acid transport 0.907582 31253 cell projection membrane 0.907539 45047 protein targeting to ER 0.907520 6614 SRP-dependent cotranslational protein targeting to membrane 0.907520 1542 ovulation from ovarian follicle 0.907498 43256 laminin complex 0.907473 4363 glutathione synthase activity 0.907432 4831 tyrosine-tRNA ligase activity 0.907427 6437 tyrosyl-tRNA aminoacylation 0.907427 70192 chromosome organization involved in meiosis 0.907412 45667 regulation of osteoblast differentiation 0.907392 43890 N-acetylgalactosamine-6-sulfatase activity 0.907335 5459 UDP-galactose transmembrane transporter activity 0.907306 47545 2-hydroxyglutarate dehydrogenase activity 0.907287 1968 fibronectin binding 0.907248 31668 cellular response to extracellular stimulus 0.907134 71496 cellular response to external stimulus 0.907134 52 citrulline metabolic process 0.907129 31594 neuromuscular junction 0.907080 30951 establishment or maintenance of microtubule cytoskeleton polarity 0.907065 30952 establishment or maintenance of cytoskeleton polarity 0.907065 31014 troponin T binding 0.907052 70736 protein-glycine ligase activity, initiating 0.907041 7184 SMAD protein nuclear translocation 0.907039 7274 neuromuscular synaptic transmission 0.907002 85 G2 phase of mitotic cell cycle 0.906950 51319 G2 phase 0.906950 16005 phospholipase A2 activator activity 0.906900 43357 pigment cell differentiation 0.906875 43358 pigment cell differentiation 0.906875 50931 pigment cell differentiation 0.906875 42953 lipoprotein transport 0.906827 19827 stem cell maintenance 0.906813 50793 regulation of developmental process 0.906811 60002 plus-end directed microfilament motor activity 0.906804 45453 bone resorption 0.906758 6519 cellular amino acid and derivative metabolic process 0.906752 32396 inhibitory MHC class I receptor activity 0.906703 30109 HLA-B specific inhibitory MHC class I receptor activity 0.906683 30110 HLA-C specific inhibitory MHC class I receptor activity 0.906683 8119 thiopurine S-methyltransferase activity 0.906630 46498 S-adenosylhomocysteine metabolic process 0.906630 16565 general transcriptional repressor activity 0.906618 43569 negative regulation of insulin-like growth factor receptor signaling pathway 0.906602 70851 growth factor receptor binding 0.906569 6265 DNA topological change 0.906563 15361 low affinity sodium:dicarboxylate symporter activity 0.906562 43221 SMC protein binding 0.906514 5415 nucleoside:sodium symporter activity 0.906473 6693 prostaglandin metabolic process 0.906443 6692 prostanoid metabolic process 0.906443 43325 phosphatidylinositol-3,4-bisphosphate binding 0.906435 16195 exocytosis 0.906396 16194 exocytosis 0.906396 44057 regulation of system process 0.906328 10761 fibroblast migration 0.906296 48588 developmental cell growth 0.906295 4818 glutamate-tRNA ligase activity 0.906292 6424 glutamyl-tRNA aminoacylation 0.906292 30204 chondroitin sulfate metabolic process 0.906284 5068 transmembrane receptor protein tyrosine kinase adaptor protein activity 0.906283 31981 nuclear lumen 0.906273 30970 retrograde protein transport, ER to cytosol 0.906235 50688 regulation of defense response to virus 0.906177 32781 positive regulation of ATPase activity 0.906161 19217 regulation of fatty acid metabolic process 0.906091 32980 keratinocyte activation 0.906079 45502 dynein binding 0.906066 60349 bone morphogenesis 0.906054 51291 protein heterooligomerization 0.906001 46627 negative regulation of insulin receptor signaling pathway 0.905985 4747 ribokinase activity 0.905935 43985 histone H4-R3 methylation 0.905906 30060 L-malate dehydrogenase activity 0.905906 10771 negative regulation of cell morphogenesis involved in differentiation 0.905882 4827 proline-tRNA ligase activity 0.905870 6433 prolyl-tRNA aminoacylation 0.905870 30166 proteoglycan biosynthetic process 0.905831 16774 phosphotransferase activity, carboxyl group as acceptor 0.905824 7617 mating behavior 0.905813 46483 heterocycle metabolic process 0.905781 9404 toxin metabolic process 0.905752 5657 replication fork 0.905740 33619 membrane protein proteolysis 0.905739 71216 cellular response to biotic stimulus 0.905725 19432 triglyceride biosynthetic process 0.905707 15904 tetracycline transport 0.905694 15307 drug:hydrogen antiporter activity 0.905694 15520 tetracycline:hydrogen antiporter activity 0.905694 70684 seminal clot liquefaction 0.905693 4438 phosphatidylinositol-3-phosphatase activity 0.905689 8175 tRNA methyltransferase activity 0.905687 1755 neural crest cell migration 0.905678 8192 RNA guanylyltransferase activity 0.905652 36 acyl carrier activity 0.905627 5283 sodium:amino acid symporter activity 0.905625 46790 virion binding 0.905559 51101 regulation of DNA binding 0.905522 48170 positive regulation of long-term neuronal synaptic plasticity 0.905520 6701 progesterone biosynthetic process 0.905507 4027 alcohol sulfotransferase activity 0.905452 60018 astrocyte fate commitment 0.905403 47223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity 0.905399 60338 regulation of type I interferon-mediated signaling pathway 0.905326 50876 reproduction 0.905309 19953 sexual reproduction 0.905309 19952 reproduction 0.905309 42249 establishment of planar polarity of embryonic epithelium 0.905307 30490 maturation of SSU-rRNA 0.905302 6656 phosphatidylcholine biosynthetic process 0.905274 15321 sodium-dependent phosphate transmembrane transporter activity 0.905221 4796 thromboxane-A synthase activity 0.905210 43159 acrosomal matrix 0.905201 4464 leukotriene-C4 synthase activity 0.905162 8367 bacterial binding 0.905129 48665 neuron fate specification 0.905121 34599 cellular response to oxidative stress 0.905113 43625 delta DNA polymerase complex 0.905065 60627 regulation of vesicle-mediated transport 0.905020 7620 copulation 0.905017 6776 vitamin A metabolic process 0.904998 33041 sweet taste receptor activity 0.904988 1582 detection of chemical stimulus involved in sensory perception of sweet taste 0.904988 6790 sulfur metabolic process 0.904928 5697 telomerase holoenzyme complex 0.904914 4931 ATP-gated cation channel activity 0.904907 8262 importin-alpha export receptor activity 0.904872 8156 negative regulation of DNA replication 0.904824 4053 arginase activity 0.904795 8123 cholesterol 7-alpha-monooxygenase activity 0.904727 3989 acetyl-CoA carboxylase activity 0.904723 4654 polyribonucleotide nucleotidyltransferase activity 0.904679 10639 negative regulation of organelle organization 0.904677 4500 dopamine beta-monooxygenase activity 0.904641 4058 aromatic-L-amino-acid decarboxylase activity 0.904534 50910 detection of mechanical stimulus involved in sensory perception of sound 0.904534 4075 biotin carboxylase activity 0.904525 1656 metanephros development 0.904498 8455 alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity 0.904486 15718 monocarboxylic acid transport 0.904484 4052 arachidonate 12-lipoxygenase activity 0.904481 8970 phospholipase A1 activity 0.904481 2 mitochondrial genome maintenance 0.904477 8269 JAK pathway signal transduction adaptor activity 0.904457 48210 Golgi vesicle fusion to target membrane 0.904438 5285 sodium:amino acid symporter activity 0.904438 16404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity 0.904433 4515 nicotinate-nucleotide adenylyltransferase activity 0.904412 309 nicotinamide-nucleotide adenylyltransferase activity 0.904412 60060 post-embryonic retina morphogenesis in camera-type eye 0.904409 45742 positive regulation of epidermal growth factor receptor signaling pathway 0.904370 4578 chitobiosyldiphosphodolichol beta-mannosyltransferase activity 0.904341 48935 peripheral nervous system neuron development 0.904336 31306 intrinsic to mitochondrial outer membrane 0.904334 10310 regulation of hydrogen peroxide metabolic process 0.904332 4987 kappa-opioid receptor activity 0.904293 43532 angiostatin binding 0.904288 15295 solute:hydrogen symporter activity 0.904271 33781 cholesterol 24-hydroxylase activity 0.904196 16327 apicolateral plasma membrane 0.904155 35115 embryonic forelimb morphogenesis 0.904145 8312 7S RNA binding 0.904133 45766 positive regulation of angiogenesis 0.904113 43408 regulation of MAPKKK cascade 0.904109 47708 biotinidase activity 0.904051 33692 cellular polysaccharide biosynthetic process 0.903993 16127 sterol catabolic process 0.903977 6707 cholesterol catabolic process 0.903977 10821 regulation of mitochondrion organization 0.903955 16861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses 0.903939 48311 mitochondrion distribution 0.903926 47988 hydroxyacid-oxoacid transhydrogenase activity 0.903907 6388 tRNA splicing, via endonucleolytic cleavage and ligation 0.903881 394 RNA splicing, via endonucleolytic cleavage and ligation 0.903881 42773 ATP synthesis coupled electron transport 0.903865 45165 cell fate commitment 0.903862 1621 platelet ADP receptor activity 0.903858 6706 steroid catabolic process 0.903841 42553 axon ensheathment 0.903811 42552 myelination 0.903811 51321 meiotic cell cycle 0.903810 6632 regulation of fatty acid metabolic process 0.903809 30314 junctional membrane complex 0.903685 8401 retinoic acid 4-hydroxylase activity 0.903663 9308 amine metabolic process 0.903656 4800 thyroxine 5'-deiodinase activity 0.903624 46785 microtubule polymerization 0.903612 48536 spleen development 0.903562 45017 glycerolipid biosynthetic process 0.903561 43627 response to estrogen stimulus 0.903558 15172 acidic amino acid transmembrane transporter activity 0.903553 5313 L-glutamate transmembrane transporter activity 0.903553 4688 calmodulin-dependent protein kinase activity 0.903521 4685 calmodulin-dependent protein kinase activity 0.903521 4684 calmodulin-dependent protein kinase activity 0.903521 1709 cell fate determination 0.903480 47173 phosphatidylcholine-retinol O-acyltransferase activity 0.903472 42308 negative regulation of protein import into nucleus 0.903439 10927 cellular component assembly involved in morphogenesis 0.903415 43044 ATP-dependent chromatin remodeling 0.903396 46456 icosanoid biosynthetic process 0.903377 15051 X-opioid receptor activity 0.903375 302 response to reactive oxygen species 0.903358 45273 respiratory chain complex II 0.903327 902 cell morphogenesis 0.903295 30506 ankyrin binding 0.903278 48806 genitalia development 0.903215 35279 mRNA cleavage involved in gene silencing by miRNA 0.903202 15804 neutral amino acid transport 0.903198 6520 cellular amino acid metabolic process 0.903167 6365 rRNA processing 0.903160 48019 receptor antagonist activity 0.903157 30547 receptor inhibitor activity 0.903157 16628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 0.903113 32582 negative regulation of gene-specific transcription 0.903097 3881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity 0.903086 48500 signal recognition particle 0.903070 5786 signal recognition particle, endoplasmic reticulum targeting 0.903070 35121 tail morphogenesis 0.903028 46912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer 0.903019 4663 Rab geranylgeranyltransferase activity 0.902975 43522 leucine zipper domain binding 0.902951 45176 apical protein localization 0.902938 71375 cellular response to peptide hormone stimulus 0.902902 6833 water transport 0.902888 42044 fluid transport 0.902888 16528 sarcoplasm 0.902844 5721 centromeric heterochromatin 0.902806 31572 G2/M transition DNA damage checkpoint 0.902776 32583 regulation of gene-specific transcription 0.902723 45843 negative regulation of striated muscle tissue development 0.902719 6044 N-acetylglucosamine metabolic process 0.902701 31233 intrinsic to external side of plasma membrane 0.902678 8241 peptidyl-dipeptidase activity 0.902674 15680 intracellular copper ion transport 0.902603 2228 natural killer cell mediated immunity 0.902574 42267 natural killer cell mediated cytotoxicity 0.902574 6084 acetyl-CoA metabolic process 0.902556 3844 1,4-alpha-glucan branching enzyme activity 0.902554 34364 high-density lipoprotein particle 0.902553 42974 retinoic acid receptor binding 0.902524 9071 serine family amino acid catabolic process 0.902493 46332 SMAD binding 0.902482 47598 7-dehydrocholesterol reductase activity 0.902410 60 protein import into nucleus, translocation 0.902409 22405 hair cycle process 0.902408 22404 molting cycle process 0.902408 32937 SREBP-SCAP-Insig complex 0.902381 48287 nucleus organization 0.902357 9062 fatty acid catabolic process 0.902352 6509 membrane protein ectodomain proteolysis 0.902338 7632 visual behavior 0.902337 30162 regulation of proteolysis 0.902336 271 polysaccharide biosynthetic process 0.902328 50851 antigen receptor-mediated signaling pathway 0.902292 30485 smooth muscle contractile fiber 0.902265 45029 UDP-activated nucleotide receptor activity 0.902260 7005 mitochondrion organization 0.902251 31683 G-protein beta/gamma-subunit binding 0.902251 19233 sensory perception of pain 0.902233 3940 L-iduronidase activity 0.902168 15701 bicarbonate transport 0.902149 16885 ligase activity, forming carbon-carbon bonds 0.902147 48659 smooth muscle cell proliferation 0.902115 45197 establishment or maintenance of epithelial cell apical/basal polarity 0.902105 48147 negative regulation of fibroblast proliferation 0.902072 7501 mesodermal cell fate specification 0.902072 8105 asymmetric protein localization 0.902068 6041 glucosamine metabolic process 0.902064 50852 T cell receptor signaling pathway 0.901947 19135 deoxyhypusine monooxygenase activity 0.901878 48538 thymus development 0.901875 1561 fatty acid alpha-oxidation 0.901792 33193 Lsd1/2 complex 0.901782 16342 catenin complex 0.901780 3964 RNA-directed DNA polymerase activity 0.901763 6099 tricarboxylic acid cycle 0.901761 46356 acetyl-CoA catabolic process 0.901761 32011 ARF protein signal transduction 0.901734 6304 DNA modification 0.901704 16096 isoprenoid metabolic process 0.901683 6720 isoprenoid metabolic process 0.901683 15936 coenzyme A metabolic process 0.901658 70016 armadillo repeat domain binding 0.901647 10921 regulation of phosphatase activity 0.901641 31468 nuclear envelope reassembly 0.901637 1841 neural tube formation 0.901618 51823 regulation of synapse structural plasticity 0.901608 6040 amino sugar metabolic process 0.901585 30307 positive regulation of cell growth 0.901584 31175 neuron projection development 0.901496 4581 dolichyl-phosphate beta-glucosyltransferase activity 0.901492 6880 intracellular sequestering of iron ion 0.901487 5250 A-type (transient outward) potassium channel activity 0.901487 15893 drug transport 0.901452 8372 cellular_component 0.901402 8268 receptor signaling protein tyrosine kinase signaling protein activity 0.901370 46316 gluconokinase activity 0.901347 47391 alkylglycerophosphoethanolamine phosphodiesterase activity 0.901299 9250 glucan biosynthetic process 0.901290 5978 glycogen biosynthetic process 0.901290 8595 determination of anterior/posterior axis, embryo 0.901250 45023 G0 to G1 transition 0.901202 35264 multicellular organism growth 0.901161 4335 galactokinase activity 0.901149 6102 isocitrate metabolic process 0.901116 34722 gamma-glutamyl-peptidase activity 0.901106 42058 regulation of epidermal growth factor receptor signaling pathway 0.901105 16863 intramolecular oxidoreductase activity, transposing C=C bonds 0.901051 51057 positive regulation of small GTPase mediated signal transduction 0.901049 9593 detection of chemical stimulus 0.901029 51960 regulation of nervous system development 0.901020 16051 carbohydrate biosynthetic process 0.901017 42303 molting cycle 0.901017 9953 dorsal/ventral pattern formation 0.900946 6690 icosanoid metabolic process 0.900904 21524 visceral motor neuron differentiation 0.900860 43499 eukaryotic cell surface binding 0.900833 30895 apolipoprotein B mRNA editing enzyme complex 0.900790 42288 MHC class I protein binding 0.900721 47734 CDP-glycerol diphosphatase activity 0.900719 43406 positive regulation of MAP kinase activity 0.900718 48167 regulation of synaptic plasticity 0.900705 4986 delta-opioid receptor activity 0.900671 6972 hyperosmotic response 0.900669 42490 mechanoreceptor differentiation 0.900654 70815 peptidyl-lysine 5-dioxygenase activity 0.900645 60193 positive regulation of lipase activity 0.900629 8274 gamma-tubulin ring complex 0.900621 931 gamma-tubulin large complex 0.900621 929 gamma-tubulin large complex 0.900621 34185 apolipoprotein binding 0.900570 6724 lipid catabolic process 0.900555 5471 ATP:ADP antiporter activity 0.900497 30291 protein serine/threonine kinase inhibitor activity 0.900475 32319 regulation of Rho GTPase activity 0.900440 1889 liver development 0.900430 6627 mitochondrial protein processing during import 0.900425 34982 mitochondrial protein processing 0.900425 16724 oxidoreductase activity, oxidizing metal ions, oxygen as acceptor 0.900420 4322 ferroxidase activity 0.900420 1578 microtubule bundle formation 0.900408 8443 phosphofructokinase activity 0.900401 10001 glial cell differentiation 0.900394 16889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters 0.900301 45736 negative regulation of cyclin-dependent protein kinase activity 0.900285 16634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 0.900279 4095 carnitine O-palmitoyltransferase activity 0.900246 16416 O-palmitoyltransferase activity 0.900246 42692 muscle cell differentiation 0.900242 6711 estrogen catabolic process 0.900237 17101 aminoacyl-tRNA synthetase multienzyme complex 0.900188 4689 phosphorylase kinase activity 0.900150 8510 sodium:bicarbonate symporter activity 0.900087 32452 histone demethylase activity 0.900063 16722 oxidoreductase activity, oxidizing metal ions 0.900052 5606 laminin-1 complex 0.900049 7521 muscle cell fate determination 0.900043 30284 estrogen receptor activity 0.900039 34464 BBSome 0.900035 30295 protein kinase activator activity 0.900005 6622 protein targeting to lysosome 0.899957 31127 alpha(1,2)-fucosyltransferase activity 0.899937 8107 galactoside 2-alpha-L-fucosyltransferase activity 0.899937 16777 intramolecular transferase activity, phosphotransferases 0.899928 6999 nuclear pore organization 0.899889 46540 U4/U6 x U5 tri-snRNP complex 0.899850 46474 glycerophospholipid biosynthetic process 0.899842 32994 protein-lipid complex 0.899836 34358 plasma lipoprotein particle 0.899836 4346 glucose-6-phosphatase activity 0.899808 6922 cleavage of lamin 0.899776 6923 cleavage of cytoskeletal proteins during apoptosis 0.899776 42755 eating behavior 0.899696 70536 protein K63-linked deubiquitination 0.899691 6006 glucose metabolic process 0.899666 6301 postreplication repair 0.899665 48813 dendrite morphogenesis 0.899635 42476 odontogenesis 0.899630 5130 granulocyte colony-stimulating factor receptor binding 0.899609 45654 positive regulation of megakaryocyte differentiation 0.899604 31091 platelet alpha granule 0.899580 780 condensed nuclear chromosome, centromeric region 0.899570 43083 synaptic cleft 0.899561 16264 gap junction assembly 0.899532 6866 amino acid transport 0.899481 31984 organelle subcompartment 0.899473 31398 positive regulation of protein ubiquitination 0.899463 32592 integral to mitochondrial membrane 0.899447 32984 macromolecular complex disassembly 0.899444 34623 cellular macromolecular complex disassembly 0.899444 48878 chemical homeostasis 0.899434 3968 RNA-directed RNA polymerase activity 0.899416 6635 fatty acid beta-oxidation 0.899384 40023 establishment of nucleus localization 0.899365 4850 uridine phosphorylase activity 0.899363 46108 uridine metabolic process 0.899363 30467 establishment or maintenance of cell polarity 0.899349 30012 establishment or maintenance of cell polarity 0.899349 10553 negative regulation of gene-specific transcription from RNA polymerase II promoter 0.899320 8890 glycine C-acetyltransferase activity 0.899319 6108 malate metabolic process 0.899311 45773 positive regulation of axon extension 0.899311 21920 regulation of transcription from RNA polymerase II promoter involved in spinal cord association neuron specification 0.899271 43241 protein complex disassembly 0.899257 43624 cellular protein complex disassembly 0.899257 47429 nucleoside-triphosphate diphosphatase activity 0.899242 6369 termination of RNA polymerase II transcription 0.899174 19784 NEDD8-specific protease activity 0.899126 45298 tubulin complex 0.899073 21537 telencephalon development 0.899052 7028 cytoplasm organization 0.899036 46879 hormone secretion 0.899019 8853 exodeoxyribonuclease III activity 0.898979 42176 regulation of protein catabolic process 0.898946 30838 positive regulation of actin filament polymerization 0.898942 47536 2-aminoadipate transaminase activity 0.898933 35313 wound healing, spreading of epidermal cells 0.898876 15813 L-glutamate transport 0.898837 15800 acidic amino acid transport 0.898837 9624 response to nematode 0.898836 42007 interleukin-18 binding 0.898788 4841 ubiquitin-protein ligase activity 0.898749 4840 ubiquitin-protein ligase activity 0.898749 34450 ubiquitin-ubiquitin ligase activity 0.898749 43171 peptide catabolic process 0.898749 60203 clathrin sculpted glutamate transport vesicle membrane 0.898740 51188 cofactor biosynthetic process 0.898694 4853 uroporphyrinogen decarboxylase activity 0.898691 46626 regulation of insulin receptor signaling pathway 0.898681 6937 regulation of muscle contraction 0.898673 4584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity 0.898643 6313 transposition, DNA-mediated 0.898638 32196 transposition 0.898638 47305 (R)-3-amino-2-methylpropionate-pyruvate transaminase activity 0.898595 70071 proton-transporting two-sector ATPase complex assembly 0.898595 46531 photoreceptor cell development 0.898594 42461 photoreceptor cell development 0.898594 42462 eye photoreceptor cell development 0.898594 32587 ruffle membrane 0.898593 32526 response to retinoic acid 0.898576 1508 regulation of action potential 0.898568 16079 synaptic vesicle exocytosis 0.898556 1846 opsonin binding 0.898556 51219 phosphoprotein binding 0.898521 4667 prostaglandin-D synthase activity 0.898493 16421 CoA carboxylase activity 0.898490 8504 monoamine transmembrane transporter activity 0.898459 30338 CMP-N-acetylneuraminate monooxygenase activity 0.898402 16212 kynurenine-oxoglutarate transaminase activity 0.898392 15871 choline transport 0.898392 15220 choline transmembrane transporter activity 0.898392 6312 mitotic recombination 0.898392 42445 hormone metabolic process 0.898335 46677 response to antibiotic 0.898331 44242 cellular lipid catabolic process 0.898303 48644 muscle organ morphogenesis 0.898237 16575 histone deacetylation 0.898224 4655 porphobilinogen synthase activity 0.898209 50769 positive regulation of neurogenesis 0.898205 10952 positive regulation of peptidase activity 0.898165 43280 positive regulation of caspase activity 0.898165 31119 tRNA pseudouridine synthesis 0.898112 47804 cysteine-S-conjugate beta-lyase activity 0.898083 1825 blastocyst formation 0.898059 30238 male sex determination 0.897976 70301 cellular response to hydrogen peroxide 0.897959 45010 actin nucleation 0.897938 43588 skin development 0.897905 774 adenyl-nucleotide exchange factor activity 0.897841 5996 monosaccharide metabolic process 0.897827 115 regulation of transcription involved in S-phase of mitotic cell cycle 0.897774 9123 nucleoside monophosphate metabolic process 0.897767 51016 barbed-end actin filament capping 0.897735 8476 protein-tyrosine sulfotransferase activity 0.897697 6478 peptidyl-tyrosine sulfation 0.897697 15095 magnesium ion transmembrane transporter activity 0.897697 8299 isoprenoid biosynthetic process 0.897695 30223 neutrophil differentiation 0.897677 21700 developmental maturation 0.897669 46579 positive regulation of Ras protein signal transduction 0.897654 16868 intramolecular transferase activity, phosphotransferases 0.897650 51371 muscle alpha-actinin binding 0.897648 50680 negative regulation of epithelial cell proliferation 0.897641 4342 glucosamine-6-phosphate deaminase activity 0.897624 31307 integral to mitochondrial outer membrane 0.897604 792 heterochromatin 0.897603 42407 cristae formation 0.897600 8409 5'-3' exonuclease activity 0.897532 6828 manganese ion transport 0.897528 21520 spinal cord motor neuron cell fate specification 0.897528 32869 cellular response to insulin stimulus 0.897512 30330 DNA damage response, signal transduction by p53 class mediator 0.897472 51324 prophase 0.897467 51149 positive regulation of muscle cell differentiation 0.897459 48747 muscle fiber development 0.897454 5222 intracellular cAMP activated cation channel activity 0.897426 17158 regulation of calcium ion-dependent exocytosis 0.897403 19048 virus-host interaction 0.897376 9914 hormone transport 0.897361 9590 detection of gravity 0.897359 5338 nucleotide-sugar transmembrane transporter activity 0.897335 35251 UDP-glucosyltransferase activity 0.897317 4980 melanocyte stimulating hormone receptor activity 0.897291 5596 collagen type XIV 0.897243 43281 regulation of caspase activity 0.897216 31526 brush border membrane 0.897165 1950 plasma membrane enriched fraction 0.897126 8645 hexose transport 0.897124 15749 monosaccharide transport 0.897124 4418 hydroxymethylbilane synthase activity 0.897098 30903 notochord development 0.897088 30660 Golgi-associated vesicle membrane 0.897083 48247 lymphocyte chemotaxis 0.897047 4958 prostaglandin F receptor activity 0.897020 7589 body fluid secretion 0.897019 48227 plasma membrane to endosome transport 0.896996 10817 regulation of hormone levels 0.896987 45604 regulation of epidermal cell differentiation 0.896937 6090 pyruvate metabolic process 0.896920 42994 cytoplasmic sequestering of transcription factor 0.896874 51287 NAD or NADH binding 0.896871 70507 regulation of microtubule cytoskeleton organization 0.896867 6094 gluconeogenesis 0.896866 42403 thyroid hormone metabolic process 0.896843 71445 cellular response to protein stimulus 0.896819 34620 cellular response to unfolded protein 0.896819 30968 endoplasmic reticulum unfolded protein response 0.896819 4603 phenylethanolamine N-methyltransferase activity 0.896808 32239 regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport 0.896781 46831 regulation of RNA export from nucleus 0.896781 18409 peptide or protein amino-terminal blocking 0.896744 9791 post-embryonic development 0.896742 43026 regulation of caspase activity 0.896738 9387 DNA topoisomerase activity 0.896735 3916 DNA topoisomerase activity 0.896735 43368 positive T cell selection 0.896721 43024 ribosomal small subunit binding 0.896686 1540 beta-amyloid binding 0.896649 8095 inositol-1,4,5-trisphosphate receptor activity 0.896648 1832 blastocyst growth 0.896621 51179 localization 0.896569 42446 hormone biosynthetic process 0.896548 8995 ribonuclease E activity 0.896518 15696 ammonium transport 0.896508 51739 ammonia transporter activity 0.896508 45653 negative regulation of megakaryocyte differentiation 0.896465 31512 motile primary cilium 0.896460 6066 alcohol metabolic process 0.896459 19227 neuronal action potential propagation 0.896422 19228 regulation of action potential in neuron 0.896392 17156 calcium ion-dependent exocytosis 0.896390 60023 soft palate development 0.896364 35303 regulation of dephosphorylation 0.896363 7447 imaginal disc pattern formation 0.896325 32568 general transcription from RNA polymerase II promoter 0.896283 4108 citrate (Si)-synthase activity 0.896277 21549 cerebellum development 0.896276 15245 fatty acid transporter activity 0.896272 43542 endothelial cell migration 0.896262 44275 cellular carbohydrate catabolic process 0.896261 30122 AP-2 adaptor complex 0.896238 42555 MCM complex 0.896229 32588 trans-Golgi network membrane 0.896219 33522 histone H2A ubiquitination 0.896202 50694 galactose 3-O-sulfotransferase activity 0.896202 1733 galactosylceramide sulfotransferase activity 0.896202 43398 HLH domain binding 0.896180 31018 endocrine pancreas development 0.896101 60323 head morphogenesis 0.896084 42825 TAP complex 0.896083 31305 integral to mitochondrial inner membrane 0.896069 4321 fatty-acyl-CoA synthase activity 0.896036 900 translation repressor activity, nucleic acid binding 0.896008 32006 regulation of TOR signaling pathway 0.896006 5771 multivesicular body 0.895970 70410 co-SMAD binding 0.895946 7413 axonal fasciculation 0.895914 4963 follicle-stimulating hormone receptor activity 0.895842 10517 regulation of phospholipase activity 0.895831 60017 parathyroid gland development 0.895817 4586 ornithine decarboxylase activity 0.895746 45785 positive regulation of cell adhesion 0.895714 10564 regulation of cell cycle process 0.895709 6664 glycolipid metabolic process 0.895701 307 cyclin-dependent protein kinase holoenzyme complex 0.895633 30318 melanocyte differentiation 0.895614 4964 lutropin-choriogonadotropic hormone receptor activity 0.895601 15179 L-amino acid transmembrane transporter activity 0.895600 16799 hydrolase activity, hydrolyzing N-glycosyl compounds 0.895566 4792 thiosulfate sulfurtransferase activity 0.895538 32810 sterol response element binding 0.895504 42562 hormone binding 0.895493 32407 MutSalpha complex binding 0.895475 8631 induction of apoptosis by oxidative stress 0.895463 31290 retinal ganglion cell axon guidance 0.895416 51235 maintenance of location 0.895407 43185 vascular endothelial growth factor receptor 3 binding 0.895403 48255 mRNA stabilization 0.895388 43489 RNA stabilization 0.895388 1667 ameboidal cell migration 0.895307 31996 thioesterase binding 0.895263 43249 erythrocyte maturation 0.895254 30324 lung development 0.895253 32528 microvillus organization 0.895214 30033 microvillus assembly 0.895214 31588 AMP-activated protein kinase complex 0.895185 4337 geranyltranstransferase activity 0.895185 4161 dimethylallyltranstransferase activity 0.895185 5082 receptor signaling protein tyrosine phosphatase signaling protein activity 0.895118 15758 glucose transport 0.895118 47696 beta-adrenergic receptor kinase activity 0.895113 3876 AMP deaminase activity 0.895092 1706 endoderm formation 0.895089 8078 mesodermal cell migration 0.895070 31529 ruffle organization 0.895058 21522 spinal cord motor neuron differentiation 0.894972 30172 troponin C binding 0.894970 48365 Rac GTPase binding 0.894952 9124 nucleoside monophosphate biosynthetic process 0.894933 32002 interleukin-28 receptor complex 0.894931 37 fatty acid biosynthetic process 0.894864 16813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 0.894817 50767 regulation of neurogenesis 0.894734 8418 protein N-terminal asparagine amidohydrolase activity 0.894683 33558 protein deacetylase activity 0.894683 4407 histone deacetylase activity 0.894683 6984 ER-nuclear signaling pathway 0.894563 7206 activation of phospholipase C activity by metabotropic glutamate receptor signaling pathway 0.894534 16053 organic acid biosynthetic process 0.894455 46394 carboxylic acid biosynthetic process 0.894455 80135 regulation of cellular response to stress 0.894443 34235 GPI anchor binding 0.894441 5597 collagen type XVI 0.894394 48041 focal adhesion formation 0.894385 4942 anaphylatoxin receptor activity 0.894351 19318 hexose metabolic process 0.894326 30516 regulation of axon extension 0.894288 31931 TORC1 complex 0.894271 6342 chromatin silencing 0.894224 43491 protein kinase B signaling cascade 0.894197 4137 deoxycytidine kinase activity 0.894152 46058 cAMP metabolic process 0.894098 16165 lipoxygenase activity 0.894078 34446 substrate adhesion-dependent cell spreading 0.894078 65001 specification of axis polarity 0.894056 42605 peptide antigen binding 0.894014 51651 maintenance of location in cell 0.893990 31345 negative regulation of cell projection organization 0.893945 8088 axon cargo transport 0.893943 30272 5-formyltetrahydrofolate cyclo-ligase activity 0.893930 35083 cilium axoneme assembly 0.893911 33273 response to vitamin 0.893890 46416 D-amino acid metabolic process 0.893885 16011 dystroglycan complex 0.893863 50917 sensory perception of umami taste 0.893832 33391 chromatoid body 0.893820 15722 canalicular bile acid transport 0.893814 21937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation 0.893809 5104 fibroblast growth factor receptor binding 0.893763 4103 choline kinase activity 0.893724 1739 sex chromatin 0.893721 43313 regulation of neutrophil degranulation 0.893718 6749 glutathione metabolic process 0.893696 46520 sphingoid biosynthetic process 0.893671 50785 advanced glycation end-product receptor activity 0.893659 32281 alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex 0.893640 47747 cholate-CoA ligase activity 0.893621 52548 regulation of endopeptidase activity 0.893595 5684 U2-type spliceosomal complex 0.893573 2097 tRNA wobble base modification 0.893521 2098 tRNA wobble uridine modification 0.893521 34227 tRNA thio-modification 0.893521 3726 double-stranded RNA adenosine deaminase activity 0.893471 6140 regulation of nucleotide metabolic process 0.893449 15185 L-gamma-aminobutyric acid transmembrane transporter activity 0.893436 32391 photoreceptor connecting cilium 0.893338 32008 positive regulation of TOR signaling pathway 0.893328 16328 lateral plasma membrane 0.893295 21913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification 0.893289 34263 autophagy in response to ER overload 0.893283 33764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.893235 42586 peptide deformylase activity 0.893235 51045 negative regulation of membrane protein ectodomain proteolysis 0.893231 47915 ganglioside galactosyltransferase activity 0.893187 16801 hydrolase activity, acting on ether bonds 0.893183 6095 carbohydrate catabolic process 0.893112 16052 carbohydrate catabolic process 0.893112 6309 DNA fragmentation involved in apoptosis 0.893093 31128 developmental induction 0.893085 45168 cell-cell signaling involved in cell fate specification 0.893085 30100 regulation of endocytosis 0.892997 30155 regulation of cell adhesion 0.892992 6282 regulation of DNA repair 0.892991 51205 protein insertion into membrane 0.892987 5851 eukaryotic translation initiation factor 2B complex 0.892968 8459 chondroitin 6-sulfotransferase activity 0.892964 1401 mitochondrial sorting and assembly machinery complex 0.892897 15914 phospholipid transport 0.892802 10518 positive regulation of phospholipase activity 0.892776 6710 androgen catabolic process 0.892698 4844 uracil DNA N-glycosylase activity 0.892676 30579 ubiquitin-dependent SMAD protein catabolic process 0.892664 43621 protein self-association 0.892641 2790 peptide secretion 0.892594 30072 peptide hormone secretion 0.892594 31293 membrane protein intracellular domain proteolysis 0.892582 45255 proton-transporting ATP synthase complex 0.892571 45259 proton-transporting ATP synthase complex 0.892571 5753 mitochondrial proton-transporting ATP synthase complex 0.892571 34440 lipid oxidation 0.892555 19395 fatty acid oxidation 0.892555 3680 AT DNA binding 0.892529 46164 alcohol catabolic process 0.892488 1945 lymph vessel development 0.892468 6119 oxidative phosphorylation 0.892444 4608 phosphatidylethanolamine N-methyltransferase activity 0.892414 9719 response to endogenous stimulus 0.892402 10587 miRNA catabolic process 0.892387 10586 miRNA metabolic process 0.892387 22411 cellular component disassembly 0.892370 50659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity 0.892366 7006 mitochondrial membrane organization 0.892340 16831 carboxy-lyase activity 0.892330 19046 reactivation of latent virus 0.892317 15359 amino acid transmembrane transporter activity 0.892301 8517 folic acid transporter activity 0.892268 48469 cell maturation 0.892266 33559 unsaturated fatty acid metabolic process 0.892251 31258 lamellipodium membrane 0.892240 31527 filopodium membrane 0.892240 16624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor 0.892221 5717 chromatin 0.892201 19059 initiation of viral infection 0.892182 43450 alkene biosynthetic process 0.892178 19370 leukotriene biosynthetic process 0.892178 70568 guanylyltransferase activity 0.892154 16830 carbon-carbon lyase activity 0.892144 19240 citrulline biosynthetic process 0.892114 70887 cellular response to chemical stimulus 0.892090 16229 steroid dehydrogenase activity 0.892083 52547 regulation of peptidase activity 0.892069 51383 kinetochore organization 0.892048 15939 pantothenate metabolic process 0.892022 10769 regulation of cell morphogenesis involved in differentiation 0.892012 21794 thalamus development 0.891998 21528 commissural neuron differentiation in the spinal cord 0.891979 60122 inner ear receptor stereocilium organization 0.891969 10569 regulation of double-strand break repair via homologous recombination 0.891853 51180 vitamin transport 0.891850 47635 alanine-oxo-acid transaminase activity 0.891805 4021 L-alanine:2-oxoglutarate aminotransferase activity 0.891805 31491 nucleosome binding 0.891792 44454 nuclear chromosome part 0.891786 8441 3'(2'),5'-bisphosphate nucleotidase activity 0.891786 42744 hydrogen peroxide catabolic process 0.891777 4609 phosphatidylserine decarboxylase activity 0.891733 6976 DNA damage response, signal transduction by p53 class mediator 0.891684 6637 acyl-CoA metabolic process 0.891575 34661 ncRNA catabolic process 0.891527 48666 neuron development 0.891520 6582 melanin metabolic process 0.891448 48155 S100 alpha binding 0.891443 8398 sterol 14-demethylase activity 0.891400 4978 adrenocorticotropin receptor activity 0.891352 42800 histone methyltransferase activity (H3-K4 specific) 0.891325 7171 activation of transmembrane receptor protein tyrosine kinase activity 0.891321 6337 nucleosome disassembly 0.891309 32986 protein-DNA complex disassembly 0.891309 17033 DNA topoisomerase I binding 0.891303 4610 phosphoacetylglucosamine mutase activity 0.891255 51349 positive regulation of lyase activity 0.891235 19798 procollagen-proline dioxygenase activity 0.891230 31017 exocrine pancreas development 0.891228 48839 inner ear development 0.891221 44087 regulation of cellular component biogenesis 0.891199 5916 fascia adherens 0.891148 6919 activation of caspase activity 0.891125 8097 5S rRNA binding 0.891110 7309 oocyte axis specification 0.891032 4771 sterol esterase activity 0.890960 30315 T-tubule 0.890953 9798 axis specification 0.890949 45046 protein import into peroxisome membrane 0.890939 33261 regulation of S phase 0.890865 5863 striated muscle thick filament 0.890863 30799 regulation of cyclic nucleotide metabolic process 0.890840 30618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity 0.890780 70267 oncosis 0.890772 15633 zinc transporting ATPase activity 0.890724 21515 cell differentiation in spinal cord 0.890714 4416 hydroxyacylglutathione hydrolase activity 0.890676 31941 filamentous actin 0.890674 1938 positive regulation of endothelial cell proliferation 0.890657 5637 nuclear inner membrane 0.890633 10035 response to inorganic substance 0.890579 60011 Sertoli cell proliferation 0.890552 3831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity 0.890536 50827 toxin receptor binding 0.890531 6929 substrate-bound cell migration 0.890520 48251 elastic fiber assembly 0.890503 7128 meiotic prophase I 0.890481 4067 asparaginase activity 0.890467 4530 deoxyribonuclease I activity 0.890386 5375 copper ion transmembrane transporter activity 0.890384 2318 myeloid progenitor cell differentiation 0.890381 21879 forebrain neuron differentiation 0.890311 42731 PH domain binding 0.890289 4168 dolichol kinase activity 0.890212 8108 UDP-glucose:hexose-1-phosphate uridylyltransferase activity 0.890193 6544 glycine metabolic process 0.890192 1678 cellular glucose homeostasis 0.890094 6082 organic acid metabolic process 0.890078 10810 regulation of cell-substrate adhesion 0.890078 6817 phosphate transport 0.890071 32060 bleb formation 0.890056 35025 positive regulation of Rho protein signal transduction 0.889984 30802 regulation of cyclic nucleotide biosynthetic process 0.889959 30808 regulation of nucleotide biosynthetic process 0.889959 15277 kainate selective glutamate receptor activity 0.889830 4361 glutaryl-CoA dehydrogenase activity 0.889806 6977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 0.889804 71156 regulation of cell cycle arrest 0.889804 71158 positive regulation of cell cycle arrest 0.889804 4489 methylenetetrahydrofolate reductase (NADPH) activity 0.889758 42050 protein amino acid lipidation 0.889740 30545 receptor regulator activity 0.889711 50778 positive regulation of immune response 0.889638 9311 oligosaccharide metabolic process 0.889637 8924 malate dehydrogenase (acceptor) activity 0.889613 1885 endothelial cell development 0.889609 48168 regulation of neuronal synaptic plasticity 0.889563 45217 cell-cell junction maintenance 0.889549 34331 cell junction maintenance 0.889549 47192 1-alkylglycerophosphocholine O-acetyltransferase activity 0.889535 6353 transcription termination 0.889505 154 rRNA modification 0.889498 7091 mitotic metaphase/anaphase transition 0.889458 45665 negative regulation of neuron differentiation 0.889448 43436 oxoacid metabolic process 0.889444 19752 carboxylic acid metabolic process 0.889444 30297 transmembrane receptor protein tyrosine kinase activator activity 0.889416 4947 bradykinin receptor activity 0.889415 6081 cellular aldehyde metabolic process 0.889406 31281 positive regulation of cyclase activity 0.889406 4911 interleukin-2 receptor activity 0.889393 19976 interleukin-2 binding 0.889393 7611 learning or memory 0.889366 45727 positive regulation of translation 0.889362 15833 peptide transport 0.889346 8174 mRNA methyltransferase activity 0.889329 4730 pseudouridylate synthase activity 0.889323 30070 insulin processing 0.889318 18193 peptidyl-amino acid modification 0.889314 51480 cytosolic calcium ion homeostasis 0.889211 43154 negative regulation of caspase activity 0.889196 4907 cytokine receptor activity 0.889180 45948 positive regulation of translational initiation 0.889167 6400 tRNA modification 0.889159 797 condensin core heterodimer 0.889130 19722 calcium-mediated signaling 0.889130 4142 diacylglycerol cholinephosphotransferase activity 0.889104 3860 3-hydroxyisobutyryl-CoA hydrolase activity 0.889082 4516 nicotinate phosphoribosyltransferase activity 0.889077 4024 alcohol dehydrogenase activity, zinc-dependent 0.889066 17031 Rho GTPase binding 0.889036 9636 response to toxin 0.889036 1823 mesonephros development 0.889028 42567 insulin-like growth factor ternary complex 0.888985 42180 cellular ketone metabolic process 0.888974 31099 regeneration 0.888951 43473 pigmentation 0.888949 34976 response to endoplasmic reticulum stress 0.888942 70566 adenylyltransferase activity 0.888892 31396 regulation of protein ubiquitination 0.888880 10669 epithelial structure maintenance 0.888878 30277 maintenance of gastrointestinal epithelium 0.888878 6305 DNA alkylation 0.888878 6306 DNA methylation 0.888878 8607 phosphorylase kinase regulator activity 0.888849 15106 bicarbonate transmembrane transporter activity 0.888846 338 protein deneddylation 0.888841 60041 retina development in camera-type eye 0.888836 48280 vesicle fusion with Golgi apparatus 0.888792 34619 cellular chaperone-mediated protein complex assembly 0.888787 43449 cellular alkene metabolic process 0.888774 4479 methionyl-tRNA formyltransferase activity 0.888744 14701 junctional sarcoplasmic reticulum membrane 0.888694 31667 response to nutrient levels 0.888687 70193 synaptonemal complex organization 0.888655 7130 synaptonemal complex assembly 0.888655 5550 pheromone binding 0.888647 8470 isovaleryl-CoA dehydrogenase activity 0.888599 6883 cellular sodium ion homeostasis 0.888594 70303 negative regulation of stress-activated protein kinase signaling pathway 0.888555 46329 negative regulation of JNK cascade 0.888555 9082 branched chain family amino acid biosynthetic process 0.888545 4084 branched-chain-amino-acid transaminase activity 0.888545 4900 erythropoietin receptor activity 0.888503 70325 lipoprotein receptor binding 0.888446 50771 negative regulation of axonogenesis 0.888437 45518 interleukin-22 receptor binding 0.888406 16405 CoA-ligase activity 0.888367 6335 DNA replication-dependent nucleosome assembly 0.888304 34723 DNA replication-dependent nucleosome organization 0.888304 1555 oocyte growth 0.888261 6688 glycosphingolipid biosynthetic process 0.888261 16198 axon choice point recognition 0.888234 7162 negative regulation of cell adhesion 0.888115 125 PCAF complex 0.888114 10002 cardioblast differentiation 0.888068 38 very-long-chain fatty acid metabolic process 0.888060 48534 hemopoietic or lymphoid organ development 0.888058 9648 photoperiodism 0.888038 1849 complement component C1q binding 0.888025 8449 N-acetylglucosamine-6-sulfatase activity 0.888020 10457 centriole-centriole cohesion 0.887971 8778 acyl-CoA thioesterase activity 0.887932 16292 acyl-CoA thioesterase activity 0.887932 16290 palmitoyl-CoA hydrolase activity 0.887932 42256 mature ribosome assembly 0.887923 70252 actin-mediated cell contraction 0.887885 33275 actin-myosin filament sliding 0.887885 30049 muscle filament sliding 0.887885 10038 response to metal ion 0.887742 8628 induction of apoptosis by hormones 0.887735 35081 induction of programmed cell death by hormones 0.887735 19834 phospholipase A2 inhibitor activity 0.887687 16340 calcium-dependent cell-matrix adhesion 0.887633 6691 leukotriene metabolic process 0.887612 51457 maintenance of protein location in nucleus 0.887601 68 chromosome condensation 0.887600 45121 membrane raft 0.887594 1760 aminocarboxymuconate-semialdehyde decarboxylase activity 0.887585 5913 cell-cell adherens junction 0.887582 578 embryonic axis specification 0.887557 4326 tetrahydrofolylpolyglutamate synthase activity 0.887537 16477 cell migration 0.887522 17015 regulation of transforming growth factor beta receptor signaling pathway 0.887514 8356 asymmetric cell division 0.887489 4448 isocitrate dehydrogenase activity 0.887457 15378 sodium:chloride symporter activity 0.887440 4659 prenyltransferase activity 0.887421 33043 regulation of organelle organization 0.887298 9399 nitrogen fixation 0.887247 32797 SMN complex 0.887242 45762 positive regulation of adenylate cyclase activity 0.887238 5663 DNA replication factor C complex 0.887220 43487 regulation of RNA stability 0.887171 43488 regulation of mRNA stability 0.887171 48738 cardiac muscle tissue development 0.887169 42572 retinol metabolic process 0.887112 8267 poly-glutamine tract binding 0.887102 34587 piRNA metabolic process 0.887074 31344 regulation of cell projection organization 0.887062 50104 L-gulonate 3-dehydrogenase activity 0.887054 8144 drug binding 0.887031 4945 angiotensin type II receptor activity 0.887025 1595 angiotensin receptor activity 0.887025 6636 unsaturated fatty acid biosynthetic process 0.887018 1957 intramembranous ossification 0.886995 21533 cell differentiation in hindbrain 0.886982 17144 drug metabolic process 0.886962 42471 ear morphogenesis 0.886957 16886 ligase activity, forming phosphoric ester bonds 0.886926 7052 mitotic spindle organization 0.886901 5137 interleukin-5 receptor binding 0.886879 70569 uridylyltransferase activity 0.886858 7212 dopamine receptor signaling pathway 0.886845 6824 cobalt ion transport 0.886825 187 activation of MAPK activity 0.886823 15266 protein channel activity 0.886764 50801 ion homeostasis 0.886742 8385 IkappaB kinase complex 0.886672 16287 glycerone-phosphate O-acyltransferase activity 0.886668 31111 negative regulation of microtubule polymerization or depolymerization 0.886661 42354 L-fucose metabolic process 0.886657 16668 oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor 0.886611 16654 oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor 0.886611 16907 G-protein coupled acetylcholine receptor activity 0.886578 4981 muscarinic acetylcholine receptor activity 0.886578 4146 dihydrofolate reductase activity 0.886541 6284 base-excision repair 0.886535 16358 dendrite development 0.886505 8553 hydrogen-exporting ATPase activity, phosphorylative mechanism 0.886482 320 re-entry into mitotic cell cycle 0.886434 15801 aromatic amino acid transport 0.886421 2046 opsin binding 0.886330 33189 response to vitamin A 0.886313 7252 I-kappaB phosphorylation 0.886303 7250 activation of NF-kappaB-inducing kinase activity 0.886281 16548 rRNA modification 0.886259 15026 coreceptor activity 0.886215 43045 DNA methylation during embryonic development 0.886179 16478 negative regulation of translation 0.886153 16312 inositol bisphosphate phosphatase activity 0.886131 272 polysaccharide catabolic process 0.886125 19226 transmission of nerve impulse 0.886076 45321 leukocyte activation 0.886069 30891 VCB complex 0.886010 4494 methylmalonyl-CoA mutase activity 0.885992 55086 nucleobase, nucleoside and nucleotide metabolic process 0.885794 6449 regulation of translational termination 0.885793 48610 reproductive cellular process 0.885786 6455 translational elongation 0.885786 6451 translational readthrough 0.885786 6442 translational elongation 0.885786 1514 selenocysteine incorporation 0.885786 5790 smooth endoplasmic reticulum 0.885739 6349 regulation of gene expression by genetic imprinting 0.885736 71514 genetic imprinting 0.885736 70302 regulation of stress-activated protein kinase signaling pathway 0.885700 30814 regulation of cAMP metabolic process 0.885696 55082 cellular chemical homeostasis 0.885693 42577 lipid phosphatase activity 0.885648 8483 transaminase activity 0.885603 51014 actin filament severing 0.885601 9725 response to hormone stimulus 0.885561 6906 vesicle fusion 0.885545 5720 nuclear heterochromatin 0.885540 46974 histone methyltransferase activity (H3-K9 specific) 0.885503 19047 provirus integration 0.885488 8559 xenobiotic-transporting ATPase activity 0.885482 15239 multidrug transporter activity 0.885482 42910 xenobiotic transporter activity 0.885482 17151 DEAD/H-box RNA helicase binding 0.885479 10860 proteasome regulator activity 0.885465 47395 glycerophosphoinositol glycerophosphodiesterase activity 0.885460 3009 skeletal muscle contraction 0.885440 17148 negative regulation of translation 0.885427 8016 regulation of heart contraction 0.885425 42608 T cell receptor binding 0.885417 33036 macromolecule localization 0.885403 7044 cell-substrate junction assembly 0.885396 31543 peptidyl-proline dioxygenase activity 0.885373 6873 cellular ion homeostasis 0.885364 1775 cell activation 0.885277 34614 cellular response to reactive oxygen species 0.885261 8426 protein kinase C inhibitor activity 0.885238 8366 axon ensheathment 0.885226 7272 ensheathment of neurons 0.885226 137 Golgi cis cisterna 0.885160 31536 positive regulation of exit from mitosis 0.885144 6467 protein thiol-disulfide exchange 0.885135 7204 elevation of cytosolic calcium ion concentration 0.885130 35034 histone acetyltransferase regulator activity 0.885122 45947 negative regulation of translational initiation 0.885073 44093 positive regulation of molecular function 0.885037 7190 activation of adenylate cyclase activity 0.885025 70761 pre-snoRNP complex 0.885022 19209 kinase activator activity 0.885019 4577 N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity 0.884978 30262 apoptotic nuclear changes 0.884973 5592 collagen type XI 0.884972 6763 coenzyme A metabolic process 0.884966 15937 coenzyme A biosynthetic process 0.884966 60216 definitive hemopoiesis 0.884888 4043 L-aminoadipate-semialdehyde dehydrogenase activity 0.884881 6808 regulation of nitrogen utilization 0.884875 43130 ubiquitin binding 0.884800 32182 small conjugating protein binding 0.884800 182 rDNA binding 0.884784 51347 positive regulation of transferase activity 0.884772 19200 carbohydrate kinase activity 0.884750 15139 alpha-ketoglutarate transmembrane transporter activity 0.884736 46513 ceramide biosynthetic process 0.884708 10863 positive regulation of phospholipase C activity 0.884686 7202 activation of phospholipase C activity 0.884686 43855 cyclic nucleotide-gated ion channel activity 0.884685 5221 intracellular cyclic nucleotide activated cation channel activity 0.884685 50901 leukocyte tethering or rolling 0.884646 30225 macrophage differentiation 0.884612 30817 regulation of cAMP biosynthetic process 0.884591 8203 cholesterol metabolic process 0.884557 19221 cytokine-mediated signaling pathway 0.884548 16903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 0.884485 46519 sphingoid metabolic process 0.884476 10970 microtubule-based transport 0.884430 19751 polyol metabolic process 0.884429 31406 carboxylic acid binding 0.884403 43162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 0.884393 90092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 0.884382 51920 peroxiredoxin activity 0.884378 4496 mevalonate kinase activity 0.884302 5343 organic acid:sodium symporter activity 0.884252 30061 mitochondrial crista 0.884248 7320 insemination 0.884226 4808 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity 0.884205 8281 sulfonylurea receptor activity 0.884175 32508 DNA duplex unwinding 0.884164 32392 DNA geometric change 0.884164 45277 respiratory chain complex IV 0.884162 45287 respiratory chain complex IV 0.884162 5751 mitochondrial respiratory chain complex IV 0.884162 47341 fucose-1-phosphate guanylyltransferase activity 0.884157 5154 epidermal growth factor receptor binding 0.884155 6497 protein amino acid lipidation 0.884102 50661 NADP or NADPH binding 0.884088 7193 inhibition of adenylate cyclase activity by G-protein signaling pathway 0.884049 7567 parturition 0.884040 43495 protein anchor 0.884019 4569 glycoprotein endo-alpha-1,2-mannosidase activity 0.883963 14704 intercalated disc 0.883936 42156 zinc-mediated transcriptional activator activity 0.883915 31497 chromatin assembly 0.883903 6882 cellular zinc ion homeostasis 0.883898 8448 N-acetylglucosamine-6-phosphate deacetylase activity 0.883867 31346 positive regulation of cell projection organization 0.883865 3896 DNA primase activity 0.883814 129 DNA-directed RNA polymerase activity 0.883814 5047 signal recognition particle binding 0.883802 16181 synaptic vesicle transport 0.883797 42592 homeostatic process 0.883785 30705 cytoskeleton-dependent intracellular transport 0.883775 6560 proline metabolic process 0.883737 7497 posterior midgut development 0.883716 275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) 0.883693 51339 regulation of lyase activity 0.883655 7088 regulation of mitosis 0.883646 51783 regulation of nuclear division 0.883646 45898 regulation of RNA polymerase II transcriptional preinitiation complex assembly 0.883645 4565 beta-galactosidase activity 0.883644 31362 anchored to external side of plasma membrane 0.883597 8273 calcium, potassium:sodium antiporter activity 0.883572 1505 regulation of neurotransmitter levels 0.883564 46328 regulation of JNK cascade 0.883554 48213 Golgi vesicle prefusion complex stabilization 0.883432 50962 detection of light stimulus involved in sensory perception 0.883419 50908 detection of light stimulus involved in visual perception 0.883419 6926 virus-infected cell apoptosis 0.883415 43574 peroxisomal transport 0.883394 60009 Sertoli cell development 0.883378 45974 regulation of translation, ncRNA-mediated 0.883371 35278 negative regulation of translation involved in gene silencing by miRNA 0.883371 40033 negative regulation of translation, ncRNA-mediated 0.883371 51128 regulation of cellular component organization 0.883369 43550 regulation of lipid kinase activity 0.883364 7031 peroxisome organization 0.883351 7624 ultradian rhythm 0.883336 9794 regulation of mitotic cell cycle, embryonic 0.883287 48468 cell development 0.883286 8437 thyrotropin-releasing hormone activity 0.883239 18202 peptidyl-histidine modification 0.883233 43027 caspase inhibitor activity 0.883206 2064 epithelial cell development 0.883187 1631 cysteinyl leukotriene receptor activity 0.883143 16423 tRNA (guanine) methyltransferase activity 0.883130 16424 tRNA (guanine) methyltransferase activity 0.883130 4034 aldose 1-epimerase activity 0.883094 33674 positive regulation of kinase activity 0.883046 8453 alanine-glyoxylate transaminase activity 0.883003 34362 low-density lipoprotein particle 0.882956 21527 spinal cord association neuron differentiation 0.882906 4573 mannosyl-oligosaccharide glucosidase activity 0.882901 5827 polar microtubule 0.882895 9948 anterior/posterior axis specification 0.882885 7492 endoderm development 0.882818 31114 regulation of microtubule depolymerization 0.882809 7026 negative regulation of microtubule depolymerization 0.882809 8474 palmitoyl-(protein) hydrolase activity 0.882799 42162 telomeric DNA binding 0.882796 45664 regulation of neuron differentiation 0.882764 16846 carbon-sulfur lyase activity 0.882670 8251 tRNA-specific adenosine deaminase activity 0.882660 15015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification 0.882616 51233 spindle midzone 0.882594 9117 nucleotide metabolic process 0.882587 6753 nucleoside phosphate metabolic process 0.882587 2070 epithelial cell maturation 0.882579 16558 protein import into peroxisome matrix 0.882577 173 inactivation of MAPK activity involved in osmosensory signaling pathway 0.882563 48389 intermediate mesoderm development 0.882515 40009 regulation of growth rate 0.882509 30258 lipid modification 0.882458 30048 actin filament-based movement 0.882448 45930 negative regulation of mitotic cell cycle 0.882434 46899 nucleoside triphosphate adenylate kinase activity 0.882418 45860 positive regulation of protein kinase activity 0.882409 4677 DNA-dependent protein kinase activity 0.882340 31279 regulation of cyclase activity 0.882333 31576 G2/M transition checkpoint 0.882326 15721 bile acid and bile salt transport 0.882317 8176 tRNA (guanine-N7-)-methyltransferase activity 0.882292 35173 histone kinase activity 0.882292 40029 regulation of gene expression, epigenetic 0.882256 47499 calcium-independent phospholipase A2 activity 0.882220 19109 acyl-CoA dehydrogenase activity 0.882202 43405 regulation of MAP kinase activity 0.882194 32507 maintenance of protein location in cell 0.882178 3958 NADPH-hemoprotein reductase activity 0.882177 19862 IgA binding 0.882147 47497 mitochondrion transport along microtubule 0.882125 51654 establishment of mitochondrion localization 0.882125 34643 mitochondrion localization, microtubule-mediated 0.882125 5797 Golgi medial cisterna 0.882123 4870 cysteine-type endopeptidase inhibitor activity 0.882094 5172 vascular endothelial growth factor receptor binding 0.882039 31985 Golgi cisterna 0.882035 21526 medial motor column neuron differentiation 0.882032 8466 glycogenin glucosyltransferase activity 0.882014 30177 positive regulation of Wnt receptor signaling pathway 0.882005 48015 phosphoinositide-mediated signaling 0.881996 31110 regulation of microtubule polymerization or depolymerization 0.881991 4773 steryl-sulfatase activity 0.881984 33765 steroid dehydrogenase activity, acting on the CH-CH group of donors 0.881972 3865 3-oxo-5-alpha-steroid 4-dehydrogenase activity 0.881972 22614 membrane to membrane docking 0.881971 3857 3-hydroxyacyl-CoA dehydrogenase activity 0.881891 65008 regulation of biological quality 0.881857 9991 response to extracellular stimulus 0.881855 9673 low affinity phosphate transmembrane transporter activity 0.881839 55072 iron ion homeostasis 0.881694 48741 skeletal muscle fiber development 0.881690 33165 interphotoreceptor matrix 0.881646 5892 nicotinic acetylcholine-gated receptor-channel complex 0.881570 790 nuclear chromatin 0.881553 16519 gastric inhibitory peptide receptor activity 0.881501 1510 RNA methylation 0.881478 4832 valine-tRNA ligase activity 0.881471 6438 valyl-tRNA aminoacylation 0.881471 6003 fructose 2,6-bisphosphate metabolic process 0.881459 3873 6-phosphofructo-2-kinase activity 0.881459 7096 regulation of exit from mitosis 0.881430 9987 cellular process 0.881423 10033 response to organic substance 0.881407 45666 positive regulation of neuron differentiation 0.881406 50576 3-keto sterol reductase activity 0.881404 8151 cellular process 0.881396 50875 cellular process 0.881396 45110 intermediate filament bundle assembly 0.881375 6488 dolichol-linked oligosaccharide biosynthetic process 0.881350 30323 respiratory tube development 0.881254 120 RNA polymerase I transcription factor complex 0.881254 8609 alkylglycerone-phosphate synthase activity 0.881211 42771 DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis 0.881200 15129 lactate transmembrane transporter activity 0.881181 48870 cell motility 0.881166 6921 cell structure disassembly during apoptosis 0.881147 42059 negative regulation of epidermal growth factor receptor signaling pathway 0.881121 16769 transferase activity, transferring nitrogenous groups 0.881120 16670 oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor 0.881110 46365 monosaccharide catabolic process 0.881055 3854 3-beta-hydroxy-delta5-steroid dehydrogenase activity 0.881053 4520 endodeoxyribonuclease activity 0.881048 19153 protein-disulfide reductase (glutathione) activity 0.881018 3846 2-acylglycerol O-acyltransferase activity 0.881013 4750 ribulose-phosphate 3-epimerase activity 0.880970 1729 ceramide kinase activity 0.880964 10843 promoter binding 0.880954 6726 eye pigment biosynthetic process 0.880952 42441 eye pigment metabolic process 0.880952 43244 regulation of protein complex disassembly 0.880951 8665 2'-phosphotransferase activity 0.880940 45793 positive regulation of cell size 0.880928 1567 cholesterol 25-hydroxylase activity 0.880921 19695 choline metabolic process 0.880891 8747 N-acetylneuraminate lyase activity 0.880873 124 SAGA complex 0.880845 17071 intracellular cyclic nucleotide activated cation channel complex 0.880797 42803 protein homodimerization activity 0.880740 70306 lens fiber cell differentiation 0.880728 45569 TRAIL binding 0.880674 30195 negative regulation of blood coagulation 0.880673 19826 oxygen sensor activity 0.880626 16723 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor 0.880602 16331 morphogenesis of embryonic epithelium 0.880569 30670 phagocytic vesicle membrane 0.880563 16936 galactoside binding 0.880535 4109 coproporphyrinogen oxidase activity 0.880529 30199 collagen fibril organization 0.880524 8200 ion channel inhibitor activity 0.880512 16248 channel inhibitor activity 0.880512 33233 regulation of protein sumoylation 0.880506 33235 positive regulation of protein sumoylation 0.880506 3917 DNA topoisomerase type I activity 0.880494 8147 structural constituent of bone 0.880481 46934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity 0.880473 45761 regulation of adenylate cyclase activity 0.880460 22415 viral reproductive process 0.880458 16050 vesicle organization 0.880451 17160 Ral GTPase binding 0.880443 4936 alpha-adrenergic receptor activity 0.880402 18184 protein amino acid polyamination 0.880390 60537 muscle tissue development 0.880366 43085 positive regulation of catalytic activity 0.880363 21702 cerebellar Purkinje cell differentiation 0.880353 51721 protein phosphatase 2A binding 0.880320 4560 alpha-L-fucosidase activity 0.880312 15928 fucosidase activity 0.880312 17080 sodium channel regulator activity 0.880297 6658 phosphatidylserine metabolic process 0.880289 4920 interleukin-10 receptor activity 0.880288 19969 interleukin-10 binding 0.880288 30948 negative regulation of vascular endothelial growth factor receptor signaling pathway 0.880215 31274 positive regulation of pseudopodium assembly 0.880168 31272 regulation of pseudopodium assembly 0.880168 46933 hydrogen ion transporting ATP synthase activity, rotational mechanism 0.880142 70552 BRISC complex 0.880107 4817 cysteine-tRNA ligase activity 0.880095 45899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly 0.880095 6423 cysteinyl-tRNA aminoacylation 0.880095 4111 creatine kinase activity 0.880083 31129 inductive cell-cell signaling 0.880052 6268 DNA unwinding during replication 0.879997 70567 cytidylyltransferase activity 0.879983 1758 retinal dehydrogenase activity 0.879960 8444 CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity 0.879956 18105 peptidyl-serine phosphorylation 0.879935 50700 CARD domain binding 0.879935 16125 sterol metabolic process 0.879934 10851 cyclase regulator activity 0.879921 30249 guanylate cyclase regulator activity 0.879921 34330 cell junction organization 0.879915 47290 (alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity 0.879907 44212 DNA regulatory region binding 0.879893 2009 morphogenesis of an epithelium 0.879890 42062 long-term strengthening of neuromuscular junction 0.879877 146 microfilament motor activity 0.879855 55080 cation homeostasis 0.879841 5590 collagen type VII 0.879714 186 activation of MAPKK activity 0.879656 5246 calcium channel regulator activity 0.879642 7188 G-protein signaling, coupled to cAMP nucleotide second messenger 0.879557 5055 laminin receptor activity 0.879521 51494 negative regulation of cytoskeleton organization 0.879397 8630 DNA damage response, signal transduction resulting in induction of apoptosis 0.879383 3 reproduction 0.879357 7200 activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger 0.879355 4591 oxoglutarate dehydrogenase (succinyl-transferring) activity 0.879332 32486 Rap protein signal transduction 0.879328 16615 malate dehydrogenase activity 0.879257 43414 macromolecule methylation 0.879220 7207 activation of phospholipase C activity by muscarinic acetylcholine receptor signaling pathway 0.879220 55074 calcium ion homeostasis 0.879199 46649 lymphocyte activation 0.879184 6027 glycosaminoglycan catabolic process 0.879172 8228 opsonization 0.879089 50819 negative regulation of coagulation 0.879085 70735 protein-glycine ligase activity 0.879043 18094 protein polyglycylation 0.879043 4551 nucleotide diphosphatase activity 0.879039 4376 glycolipid mannosyltransferase activity 0.879038 46486 glycerolipid metabolic process 0.879010 4567 beta-mannosidase activity 0.878990 6476 protein amino acid deacetylation 0.878973 8493 tetracycline transporter activity 0.878920 42895 antibiotic transporter activity 0.878920 42166 acetylcholine binding 0.878893 6686 sphingomyelin biosynthetic process 0.878882 17022 myosin binding 0.878808 90066 regulation of anatomical structure size 0.878805 6546 glycine catabolic process 0.878803 31432 titin binding 0.878741 42805 actinin binding 0.878719 1931 uropod 0.878707 16939 kinesin II complex 0.878700 6941 striated muscle contraction 0.878674 4988 mu-opioid receptor activity 0.878652 1570 vasculogenesis 0.878627 4825 methionine-tRNA ligase activity 0.878610 6431 methionyl-tRNA aminoacylation 0.878610 16263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity 0.878604 8419 RNA lariat debranching enzyme activity 0.878555 45333 cellular respiration 0.878526 16745 transferase activity, transferring aldehyde or ketonic groups 0.878501 16744 transferase activity, transferring aldehyde or ketonic groups 0.878501 35110 leg morphogenesis 0.878459 8900 hydrogen:potassium-exchanging ATPase activity 0.878431 42074 cell migration involved in gastrulation 0.878393 6007 glucose catabolic process 0.878390 21615 glossopharyngeal nerve morphogenesis 0.878334 30353 fibroblast growth factor receptor antagonist activity 0.878333 1521 fibroblast growth factor receptor binding 0.878333 5152 interleukin-1 receptor antagonist activity 0.878333 5162 fibroblast growth factor receptor binding 0.878333 45335 phagocytic vesicle 0.878332 6990 positive regulation of gene-specific transcription involved in unfolded protein response 0.878217 8327 methyl-CpG binding 0.878187 6661 phosphatidylinositol biosynthetic process 0.878164 32116 cohesin loading complex 0.878163 7631 feeding behavior 0.878094 30285 integral to synaptic vesicle membrane 0.878093 55065 metal ion homeostasis 0.878063 4016 adenylate cyclase activity 0.878056 8537 proteasome activator complex 0.878044 45309 protein phosphorylated amino acid binding 0.877961 43596 nuclear replication fork 0.877927 16525 negative regulation of angiogenesis 0.877890 4631 phosphomevalonate kinase activity 0.877879 4572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity 0.877873 19320 hexose catabolic process 0.877811 10975 regulation of neuron projection development 0.877802 9101 glycoprotein biosynthetic process 0.877776 491 small nucleolar ribonucleoprotein complex assembly 0.877755 492 box C/D snoRNP assembly 0.877755 19215 intermediate filament binding 0.877723 5513 detection of calcium ion 0.877719 60113 inner ear receptor cell differentiation 0.877717 16620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 0.877684 33814 propanoyl-CoA C-acyltransferase activity 0.877638 9416 response to light stimulus 0.877631 6695 cholesterol biosynthetic process 0.877550 50508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity 0.877417 3839 gamma-glutamylcyclotransferase activity 0.877396 42641 actomyosin 0.877394 7340 acrosome reaction 0.877348 9893 positive regulation of metabolic process 0.877329 31167 rRNA methylation 0.877282 46961 proton-transporting ATPase activity, rotational mechanism 0.877279 6672 ceramide metabolic process 0.877262 4022 alcohol dehydrogenase (NAD) activity 0.877236 4064 arylesterase activity 0.877222 6874 cellular calcium ion homeostasis 0.877198 1741 XY body 0.877175 5157 macrophage colony stimulating factor receptor binding 0.877173 8511 sodium:potassium:chloride symporter activity 0.877149 4830 tryptophan-tRNA ligase activity 0.877125 6436 tryptophanyl-tRNA aminoacylation 0.877125 254 C-4 methylsterol oxidase activity 0.877107 15238 drug transporter activity 0.877091 30003 cellular cation homeostasis 0.877086 43303 mast cell degranulation 0.877079 10212 response to ionizing radiation 0.877072 16860 intramolecular oxidoreductase activity 0.876997 30073 insulin secretion 0.876966 7040 lysosome organization 0.876958 9405 pathogenesis 0.876954 9409 response to cold 0.876929 1650 fibrillar center 0.876913 1940 male pronucleus 0.876902 4621 glycosylphosphatidylinositol phospholipase D activity 0.876865 32989 cellular component morphogenesis 0.876843 17049 GTP-Rho binding 0.876832 70063 RNA polymerase binding 0.876821 9165 nucleotide biosynthetic process 0.876819 7530 sex determination 0.876776 15711 organic anion transport 0.876769 4509 steroid 21-monooxygenase activity 0.876769 16403 dimethylargininase activity 0.876763 16176 superoxide-generating NADPH oxidase activator activity 0.876763 30677 ribonuclease P complex 0.876747 30681 multimeric ribonuclease P complex 0.876747 5655 nucleolar ribonuclease P complex 0.876747 10043 response to zinc ion 0.876658 16686 peroxidase activity 0.876624 16685 peroxidase activity 0.876624 16687 peroxidase activity 0.876624 8249 signal sequence binding 0.876550 4822 isoleucine-tRNA ligase activity 0.876545 6428 isoleucyl-tRNA aminoacylation 0.876545 55066 di-, tri-valent inorganic cation homeostasis 0.876537 16849 phosphorus-oxygen lyase activity 0.876494 7423 sensory organ development 0.876470 50821 protein stabilization 0.876384 10466 negative regulation of peptidase activity 0.876368 8079 translation termination factor activity 0.876336 3747 translation release factor activity 0.876336 42493 response to drug 0.876333 16453 C-acetyltransferase activity 0.876328 16833 oxo-acid-lyase activity 0.876184 70403 NAD binding 0.876098 51288 NAD or NADH binding 0.876098 32793 positive regulation of CREB transcription factor activity 0.876093 18209 peptidyl-serine modification 0.876081 6302 double-strand break repair 0.876022 10385 double-stranded methylated DNA binding 0.875948 4813 alanine-tRNA ligase activity 0.875920 6419 alanyl-tRNA aminoacylation 0.875920 42438 melanin biosynthetic process 0.875912 46923 ER retention sequence binding 0.875869 6013 mannose metabolic process 0.875862 45765 regulation of angiogenesis 0.875828 30515 snoRNA binding 0.875773 1848 complement binding 0.875761 17047 adrenocorticotropin-releasing hormone binding 0.875755 4475 mannose-1-phosphate guanylyltransferase activity 0.875700 8905 mannose-phosphate guanylyltransferase activity 0.875700 48706 embryonic skeletal system development 0.875695 4823 leucine-tRNA ligase activity 0.875676 4821 histidine-tRNA ligase activity 0.875676 6429 leucyl-tRNA aminoacylation 0.875676 6427 histidyl-tRNA aminoacylation 0.875676 793 condensed chromosome 0.875674 34593 phosphatidylinositol bisphosphate phosphatase activity 0.875658 34101 erythrocyte homeostasis 0.875634 4306 ethanolamine-phosphate cytidylyltransferase activity 0.875610 9187 cyclic nucleotide metabolic process 0.875538 8969 phosphohistidine phosphatase activity 0.875531 45296 cadherin binding 0.875526 5942 phosphoinositide 3-kinase complex 0.875507 50906 detection of stimulus involved in sensory perception 0.875496 50750 low-density lipoprotein receptor binding 0.875492 6659 phosphatidylserine biosynthetic process 0.875483 4144 diacylglycerol O-acyltransferase activity 0.875471 16219 GDP-dissociation stimulator activity 0.875465 51174 regulation of phosphorus metabolic process 0.875458 19220 regulation of phosphate metabolic process 0.875458 4105 choline-phosphate cytidylyltransferase activity 0.875435 225 N-acetylglucosaminylphosphatidylinositol deacetylase activity 0.875416 19933 cAMP-mediated signaling 0.875353 7064 mitotic sister chromatid cohesion 0.875338 6517 protein deglycosylation 0.875314 33897 ribonuclease T2 activity 0.875272 8374 O-acyltransferase activity 0.875271 45216 cell-cell junction organization 0.875263 51260 protein homooligomerization 0.875244 43843 ADP-specific glucokinase activity 0.875223 8589 regulation of smoothened signaling pathway 0.875193 43009 chordate embryonic development 0.875153 7009 plasma membrane organization 0.875140 9795 embryonic development 0.875112 9792 embryonic development ending in birth or egg hatching 0.875112 19213 deacetylase activity 0.875110 15085 calcium ion transmembrane transporter activity 0.875047 55102 lipase inhibitor activity 0.875021 5534 galactose binding 0.875012 43242 negative regulation of protein complex disassembly 0.874909 43034 costamere 0.874903 43666 regulation of phosphoprotein phosphatase activity 0.874891 34451 centriolar satellite 0.874828 51117 ATPase binding 0.874827 1944 vasculature development 0.874799 5332 gamma-aminobutyric acid:sodium symporter activity 0.874795 1829 trophectodermal cell differentiation 0.874783 149 SNARE binding 0.874781 8193 tRNA guanylyltransferase activity 0.874759 6171 cAMP biosynthetic process 0.874755 30676 Rac guanyl-nucleotide exchange factor activity 0.874716 6875 cellular metal ion homeostasis 0.874713 30482 actin filament bundle 0.874678 1725 stress fiber 0.874678 32432 actin filament bundle 0.874678 141 actin filament bundle 0.874678 9060 aerobic respiration 0.874671 42325 regulation of phosphorylation 0.874623 6415 translational termination 0.874616 6625 protein targeting to peroxisome 0.874609 31325 positive regulation of cellular metabolic process 0.874565 1701 in utero embryonic development 0.874515 47933 glucose-1,6-bisphosphate synthase activity 0.874499 5353 fructose transmembrane transporter activity 0.874493 15320 phosphate carrier activity 0.874402 45817 positive regulation of transcription from RNA polymerase II promoter, global 0.874390 30097 hemopoiesis 0.874345 10647 positive regulation of cell communication 0.874328 70050 neuron homeostasis 0.874326 31462 Cul2-RING ubiquitin ligase complex 0.874306 22603 regulation of anatomical structure morphogenesis 0.874298 33108 mitochondrial respiratory chain complex assembly 0.874295 6072 glycerol-3-phosphate metabolic process 0.874292 47710 bis(5'-adenosyl)-triphosphatase activity 0.874258 45185 maintenance of protein location 0.874173 30546 receptor activator activity 0.874160 16504 peptidase activator activity 0.874148 5046 KDEL sequence binding 0.874131 19905 syntaxin binding 0.874095 48244 phytanoyl-CoA dioxygenase activity 0.874064 8118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity 0.873968 46982 protein heterodimerization activity 0.873956 30005 cellular di-, tri-valent inorganic cation homeostasis 0.873922 1665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity 0.873920 32787 monocarboxylic acid metabolic process 0.873859 46489 phosphoinositide biosynthetic process 0.873831 48488 synaptic vesicle endocytosis 0.873809 19136 deoxynucleoside kinase activity 0.873805 4887 thyroid hormone receptor activity 0.873793 70096 mitochondrial outer membrane translocase complex assembly 0.873744 18277 protein amino acid deamination 0.873678 35148 tube lumen formation 0.873585 6703 estrogen biosynthetic process 0.873575 30497 fatty acid elongation 0.873533 30834 regulation of actin filament depolymerization 0.873439 6561 proline biosynthetic process 0.873438 9000 selenocysteine lyase activity 0.873437 70382 exocytic vesicle 0.873424 30148 sphingolipid biosynthetic process 0.873365 4525 ribonuclease III activity 0.873344 210 NAD+ diphosphatase activity 0.873340 5547 phosphatidylinositol-3,4,5-trisphosphate binding 0.873324 42752 regulation of circadian rhythm 0.873313 16082 synaptic vesicle priming 0.873292 8048 calcium sensitive guanylate cyclase activator activity 0.873287 6029 proteoglycan metabolic process 0.873236 6163 purine nucleotide metabolic process 0.873208 90079 translation regulator activity, nucleic acid binding 0.873203 48487 beta-tubulin binding 0.873163 7616 long-term memory 0.873151 4587 ornithine-oxo-acid transaminase activity 0.873147 33270 paranode region of axon 0.873050 47238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity 0.873008 15296 anion:cation symporter activity 0.872990 3001 generation of a signal involved in cell-cell signaling 0.872966 31513 nonmotile primary cilium 0.872966 4537 caspase-activated deoxyribonuclease activity 0.872948 10859 calcium-dependent cysteine-type endopeptidase inhibitor activity 0.872906 4668 protein-arginine deiminase activity 0.872881 18101 peptidyl-citrulline biosynthetic process from peptidyl-arginine 0.872881 9925 basal plasma membrane 0.872868 6308 DNA catabolic process 0.872867 4948 calcitonin receptor activity 0.872845 30520 estrogen receptor signaling pathway 0.872813 506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex 0.872748 42770 DNA damage response, signal transduction 0.872731 32297 negative regulation of DNA replication initiation 0.872703 76 DNA replication checkpoint 0.872703 15695 organic cation transport 0.872654 17168 5-oxoprolinase (ATP-hydrolyzing) activity 0.872616 4954 prostanoid receptor activity 0.872604 4953 icosanoid receptor activity 0.872604 32268 regulation of cellular protein metabolic process 0.872564 3943 N-acetylgalactosamine-4-sulfatase activity 0.872561 8368 Gram-negative bacterial binding 0.872539 15079 potassium ion transmembrane transporter activity 0.872507 4882 androgen receptor activity 0.872441 9975 cyclase activity 0.872434 30984 kininogen binding 0.872423 30020 extracellular matrix structural constituent conferring tensile strength 0.872416 7093 mitotic cell cycle checkpoint 0.872406 16796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 0.872366 1833 inner cell mass cell proliferation 0.872335 6096 glycolysis 0.872324 44092 negative regulation of molecular function 0.872202 8431 vitamin E binding 0.872175 30864 cortical actin cytoskeleton 0.872148 1716 L-amino-acid oxidase activity 0.872133 4839 ubiquitin activating enzyme activity 0.872127 19829 cation-transporting ATPase activity 0.872104 4506 squalene monooxygenase activity 0.872085 44452 nucleolar part 0.872067 9628 response to abiotic stimulus 0.871991 31280 negative regulation of cyclase activity 0.871922 7194 negative regulation of adenylate cyclase activity 0.871922 51350 negative regulation of lyase activity 0.871922 8104 protein localization 0.871912 15250 water channel activity 0.871899 16480 negative regulation of transcription from RNA polymerase III promoter 0.871843 31206 translocon complex 0.871831 71256 translocon complex 0.871831 5784 Sec61 translocon complex 0.871831 16422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity 0.871813 5098 Ran GTPase activator activity 0.871795 6513 protein monoubiquitination 0.871788 6951 response to heat 0.871785 34605 cellular response to heat 0.871785 15370 solute:sodium symporter activity 0.871702 7025 protein folding 0.871660 7024 protein folding 0.871660 7022 protein folding 0.871660 6269 DNA replication, synthesis of RNA primer 0.871631 15174 basic amino acid transmembrane transporter activity 0.871627 15355 secondary active monocarboxylate transmembrane transporter activity 0.871616 43297 apical junction assembly 0.871547 44264 cellular polysaccharide metabolic process 0.871536 8635 activation of caspase activity by cytochrome c 0.871502 4815 aspartate-tRNA ligase activity 0.871414 6422 aspartyl-tRNA aminoacylation 0.871414 45210 FasL biosynthetic process 0.871409 8171 O-methyltransferase activity 0.871367 33209 tumor necrosis factor-mediated signaling pathway 0.871343 17169 CDP-alcohol phosphatidyltransferase activity 0.871335 14706 striated muscle tissue development 0.871316 8903 hydroxypyruvate isomerase activity 0.871215 3013 circulatory system process 0.871185 32288 myelin assembly 0.871167 4561 alpha-N-acetylglucosaminidase activity 0.871119 1568 blood vessel development 0.871082 48518 positive regulation of biological process 0.871060 43119 positive regulation of biological process 0.871060 8035 high-density lipoprotein binding 0.871039 6506 GPI anchor biosynthetic process 0.871014 46472 GPI anchor metabolic process 0.871014 1784 phosphotyrosine binding 0.870988 30863 cortical cytoskeleton 0.870947 15464 acetylcholine receptor activity 0.870924 9314 response to radiation 0.870914 18242 protein amino acid O-linked glycosylation via serine 0.870913 18243 protein amino acid O-linked glycosylation via threonine 0.870913 7041 lysosomal transport 0.870865 1838 embryonic epithelial tube formation 0.870854 6418 tRNA aminoacylation for protein translation 0.870809 43038 amino acid activation 0.870809 43039 tRNA aminoacylation 0.870809 8633 activation of pro-apoptotic gene products 0.870794 4132 dCMP deaminase activity 0.870781 35004 phosphoinositide 3-kinase activity 0.870773 33178 proton-transporting two-sector ATPase complex, catalytic domain 0.870745 46527 glucosyltransferase activity 0.870736 8456 alpha-N-acetylgalactosaminidase activity 0.870733 7603 phototransduction, visible light 0.870719 43533 inositol 1,3,4,5 tetrakisphosphate binding 0.870704 31369 translation initiation factor binding 0.870683 8213 protein amino acid alkylation 0.870669 6479 protein amino acid methylation 0.870669 6505 GPI anchor metabolic process 0.870661 10604 positive regulation of macromolecule metabolic process 0.870657 50839 cell adhesion molecule binding 0.870651 18106 peptidyl-histidine phosphorylation 0.870650 42157 lipoprotein metabolic process 0.870617 9312 oligosaccharide biosynthetic process 0.870609 31674 I band 0.870496 4809 tRNA (guanine-N2-)-methyltransferase activity 0.870485 19958 C-X-C chemokine binding 0.870447 51259 protein oligomerization 0.870421 16709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen 0.870405 16486 peptide hormone processing 0.870391 10494 stress granule 0.870350 43461 proton-transporting ATP synthase complex assembly 0.870350 7098 centrosome cycle 0.870340 1732 formation of translation initiation complex 0.870298 51493 regulation of cytoskeleton organization 0.870257 4476 mannose-6-phosphate isomerase activity 0.870243 6608 snRNP protein import into nucleus 0.870195 6997 nucleus organization 0.870085 31647 regulation of protein stability 0.870063 47874 dolichyldiphosphatase activity 0.870056 7584 response to nutrient 0.870048 31403 lithium ion binding 0.870012 30203 glycosaminoglycan metabolic process 0.870002 43209 myelin sheath 0.869993 32066 nucleolus to nucleoplasm transport 0.869912 9967 positive regulation of signal transduction 0.869907 5231 excitatory extracellular ligand-gated ion channel activity 0.869758 16614 oxidoreductase activity, acting on CH-OH group of donors 0.869742 43981 histone H4-K5 acetylation 0.869735 43983 histone H4-K12 acetylation 0.869735 43982 histone H4-K8 acetylation 0.869735 43984 histone H4-K16 acetylation 0.869735 7039 vacuolar protein catabolic process 0.869718 3988 acetyl-CoA C-acyltransferase activity 0.869712 33871 [heparan sulfate]-glucosamine 3-sulfotransferase 2 activity 0.869670 45446 endothelial cell differentiation 0.869632 15368 calcium:cation antiporter activity 0.869623 16656 monodehydroascorbate reductase (NADH) activity 0.869622 30665 clathrin coated vesicle membrane 0.869577 30662 coated vesicle membrane 0.869577 31053 primary microRNA processing 0.869548 15976 carbon utilization 0.869477 1759 induction of an organ 0.869469 6022 aminoglycan metabolic process 0.869454 51231 spindle elongation 0.869398 22 mitotic spindle elongation 0.869398 51642 centrosome localization 0.869332 70279 vitamin B6 binding 0.869270 30170 pyridoxal phosphate binding 0.869270 31365 N-terminal protein amino acid modification 0.869240 5623 cell 0.869217 84 S phase of mitotic cell cycle 0.869193 51320 S phase 0.869193 8379 thioredoxin peroxidase activity 0.869191 1632 leukotriene B4 receptor activity 0.869133 9121 ribonucleotide metabolic process 0.869130 9259 ribonucleotide metabolic process 0.869130 45745 positive regulation of G-protein coupled receptor protein signaling pathway 0.869126 32020 ISG15-protein conjugation 0.869120 18065 protein-cofactor linkage 0.868998 45098 type III intermediate filament 0.868964 731 DNA synthesis during DNA repair 0.868949 3976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity 0.868940 35005 phosphatidylinositol-4-phosphate 3-kinase activity 0.868917 42826 histone deacetylase binding 0.868853 1649 osteoblast differentiation 0.868835 31672 A band 0.868830 15294 solute:cation symporter activity 0.868830 4782 sulfinoalanine decarboxylase activity 0.868801 31211 palmitoyltransferase complex 0.868795 4758 serine C-palmitoyltransferase activity 0.868795 16454 C-palmitoyltransferase activity 0.868795 17059 serine C-palmitoyltransferase complex 0.868795 6307 DNA dealkylation 0.868788 8475 procollagen-lysine 5-dioxygenase activity 0.868772 5583 fibrillar collagen 0.868755 47184 1-acylglycerophosphocholine O-acyltransferase activity 0.868710 48736 appendage development 0.868698 60173 limb development 0.868698 42296 ISG15 ligase activity 0.868698 7566 embryo implantation 0.868674 30729 acetoacetate-CoA ligase activity 0.868656 8535 respiratory chain complex IV assembly 0.868642 51592 response to calcium ion 0.868627 3985 acetyl-CoA C-acetyltransferase activity 0.868627 33 alpha-1,3-mannosyltransferase activity 0.868595 290 deadenylation-dependent decapping of nuclear-transcribed mRNA 0.868560 45814 negative regulation of gene expression, epigenetic 0.868543 16209 antioxidant activity 0.868468 16126 sterol biosynthetic process 0.868415 4462 lactoylglutathione lyase activity 0.868415 50873 brown fat cell differentiation 0.868371 4343 glucosamine 6-phosphate N-acetyltransferase activity 0.868318 31231 intrinsic to peroxisomal membrane 0.868240 5779 integral to peroxisomal membrane 0.868240 9100 glycoprotein metabolic process 0.868198 5498 sterol binding 0.868186 15491 cation:cation antiporter activity 0.868103 50907 detection of chemical stimulus involved in sensory perception 0.868086 6979 response to oxidative stress 0.868068 50220 prostaglandin-E synthase activity 0.868064 32580 Golgi cisterna membrane 0.868047 4118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity 0.867980 7168 receptor guanylyl cyclase signaling pathway 0.867948 4408 holocytochrome-c synthase activity 0.867932 6516 glycoprotein catabolic process 0.867906 224 peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity 0.867884 1843 neural tube closure 0.867798 60606 tube closure 0.867798 15980 energy derivation by oxidation of organic compounds 0.867794 33120 positive regulation of RNA splicing 0.867787 3830 beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity 0.867739 50770 regulation of axonogenesis 0.867689 8538 proteasome activator activity 0.867683 31907 microbody lumen 0.867666 5782 peroxisomal matrix 0.867666 6998 nuclear envelope organization 0.867661 30479 actin cortical patch 0.867642 5593 FACIT collagen 0.867634 8111 alpha-methylacyl-CoA racemase activity 0.867594 48489 synaptic vesicle transport 0.867539 4047 aminomethyltransferase activity 0.867505 34220 ion transmembrane transport 0.867478 6694 steroid biosynthetic process 0.867439 43021 ribonucleoprotein binding 0.867364 50262 ribosylnicotinamide kinase activity 0.867346 50998 nitric-oxide synthase binding 0.867217 16616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.867213 4705 JUN kinase activity 0.867179 70579 methylcytosine dioxygenase activity 0.867159 30850 prostate gland development 0.867155 5502 11-cis retinal binding 0.867153 45022 early endosome to late endosome transport 0.867081 16812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 0.867038 51348 negative regulation of transferase activity 0.867025 9581 detection of external stimulus 0.866990 45730 respiratory burst 0.866979 5976 polysaccharide metabolic process 0.866934 1881 receptor recycling 0.866918 50690 regulation of defense response to virus by virus 0.866909 32981 mitochondrial respiratory chain complex I assembly 0.866893 10257 NADH dehydrogenase complex assembly 0.866893 49 tRNA binding 0.866890 31544 peptidyl-proline 3-dioxygenase activity 0.866889 19797 procollagen-proline 3-dioxygenase activity 0.866889 5183 gonadotropin hormone-releasing hormone activity 0.866869 35250 UDP-galactosyltransferase activity 0.866860 33170 protein-DNA loading ATPase activity 0.866844 3689 DNA clamp loader activity 0.866844 15932 nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity 0.866789 42246 tissue regeneration 0.866779 7443 Malpighian tubule morphogenesis 0.866725 32355 response to estradiol stimulus 0.866695 8629 induction of apoptosis by intracellular signals 0.866686 33179 proton-transporting V-type ATPase, V0 domain 0.866652 114 regulation of transcription involved in G1 phase of mitotic cell cycle 0.866628 31532 actin cytoskeleton reorganization 0.866596 725 recombinational repair 0.866593 724 double-strand break repair via homologous recombination 0.866593 35107 appendage morphogenesis 0.866538 35108 limb morphogenesis 0.866538 9386 translational attenuation 0.866483 42113 B cell activation 0.866373 15929 hexosaminidase activity 0.866356 30157 pancreatic juice secretion 0.866341 19932 second-messenger-mediated signaling 0.866303 42132 fructose 1,6-bisphosphate 1-phosphatase activity 0.866284 19911 structural constituent of myelin sheath 0.866174 4862 cAMP-dependent protein kinase inhibitor activity 0.866100 6684 sphingomyelin metabolic process 0.866094 16469 proton-transporting two-sector ATPase complex 0.866034 30151 molybdenum ion binding 0.866024 2003 angiotensin maturation 0.866018 16408 C-acyltransferase activity 0.865992 4303 estradiol 17-beta-dehydrogenase activity 0.865884 8266 poly(U) RNA binding 0.865858 33867 Fas-activated serine/threonine kinase activity 0.865855 1778 plasma membrane repair 0.865842 8210 estrogen metabolic process 0.865830 4738 pyruvate dehydrogenase activity 0.865778 4739 pyruvate dehydrogenase (acetyl-transferring) activity 0.865778 1609 adenosine receptor activity, G-protein coupled 0.865772 33293 monocarboxylic acid binding 0.865689 8892 guanine deaminase activity 0.865662 42221 response to chemical stimulus 0.865651 16569 covalent chromatin modification 0.865629 4360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity 0.865607 32970 regulation of actin filament-based process 0.865603 8286 insulin receptor signaling pathway 0.865594 71310 cellular response to organic substance 0.865585 4383 guanylate cyclase activity 0.865563 6879 cellular iron ion homeostasis 0.865505 30101 natural killer cell activation 0.865393 6164 purine nucleotide biosynthetic process 0.865382 42355 L-fucose catabolic process 0.865358 19317 fucose catabolic process 0.865358 43028 caspase regulator activity 0.865358 48522 positive regulation of cellular process 0.865346 51242 positive regulation of cellular process 0.865346 35055 regulation of nuclear mRNA splicing, via spliceosome 0.865345 4967 glucagon receptor activity 0.865342 7076 mitotic chromosome condensation 0.865297 4811 tRNA isopentenyltransferase activity 0.865276 8656 caspase activator activity 0.865219 4889 nicotinic acetylcholine-activated cation-selective channel activity 0.865202 47196 long-chain-alcohol O-fatty-acyltransferase activity 0.865149 7528 neuromuscular junction development 0.865134 7405 neuroblast proliferation 0.865130 8653 lipopolysaccharide metabolic process 0.865092 16638 oxidoreductase activity, acting on the CH-NH2 group of donors 0.865058 50913 sensory perception of bitter taste 0.865054 7215 glutamate signaling pathway 0.865032 242 pericentriolar material 0.864993 31032 actomyosin structure organization 0.864968 2252 immune effector process 0.864919 45444 fat cell differentiation 0.864898 4037 allantoicase activity 0.864890 8393 fatty acid (omega-1)-hydroxylase activity 0.864883 7141 male meiosis I 0.864747 150 recombinase activity 0.864745 16811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 0.864706 32399 HECT domain binding 0.864648 1673 male germ cell nucleus 0.864636 5315 inorganic phosphate transmembrane transporter activity 0.864635 43506 regulation of JUN kinase activity 0.864522 40007 growth 0.864517 48598 embryonic morphogenesis 0.864496 6026 aminoglycan catabolic process 0.864490 4955 prostaglandin receptor activity 0.864408 30512 negative regulation of transforming growth factor beta receptor signaling pathway 0.864402 30835 negative regulation of actin filament depolymerization 0.864389 19203 carbohydrate phosphatase activity 0.864338 51338 regulation of transferase activity 0.864260 6474 N-terminal protein amino acid acetylation 0.864243 1888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity 0.864231 5582 collagen type XV 0.864165 48137 spermatocyte division 0.864117 16657 oxidoreductase activity, acting on NADH or NADPH, nitrogenous group as acceptor 0.864110 3920 GMP reductase activity 0.864110 30282 bone mineralization 0.864106 1702 gastrulation with mouth forming second 0.864104 9304 tRNA transcription 0.864098 9190 cyclic nucleotide biosynthetic process 0.864071 51606 detection of stimulus 0.864044 30174 regulation of DNA replication initiation 0.864016 30099 myeloid cell differentiation 0.863983 46581 intercellular canaliculus 0.863975 1816 cytokine production 0.863943 16303 1-phosphatidylinositol-3-kinase activity 0.863928 293 ferric-chelate reductase activity 0.863862 9260 ribonucleotide biosynthetic process 0.863858 46467 membrane lipid biosynthetic process 0.863831 45815 positive regulation of gene expression, epigenetic 0.863829 8333 endosome to lysosome transport 0.863815 16603 glutaminyl-peptide cyclotransferase activity 0.863731 9150 purine ribonucleotide metabolic process 0.863712 44262 cellular carbohydrate metabolic process 0.863627 5903 brush border 0.863611 4423 iduronate-2-sulfatase activity 0.863586 31069 hair follicle morphogenesis 0.863537 19239 deaminase activity 0.863517 16570 histone modification 0.863493 4536 deoxyribonuclease activity 0.863435 7519 skeletal muscle tissue development 0.863371 45161 neuronal ion channel clustering 0.863368 4909 interleukin-1, Type I, activating receptor activity 0.863362 34329 cell junction assembly 0.863358 48040 UDP-glucuronate decarboxylase activity 0.863296 940 outer kinetochore of condensed chromosome 0.863268 1537 N-acetylgalactosamine 4-O-sulfotransferase activity 0.863260 7175 negative regulation of epidermal growth factor receptor activity 0.863252 46849 bone remodeling 0.863241 6092 cellular carbohydrate metabolic process 0.863142 42175 nuclear envelope-endoplasmic reticulum network 0.863121 30675 Rac GTPase activator activity 0.863111 16578 histone deubiquitination 0.863109 8907 integrase activity 0.863055 32777 Piccolo NuA4 histone acetyltransferase complex 0.862993 10181 FMN binding 0.862946 43235 receptor complex 0.862914 19807 aspartoacylase activity 0.862879 6004 fucose metabolic process 0.862770 48828 embryonic morphogenesis 0.862759 48029 monosaccharide binding 0.862731 9247 glycolipid biosynthetic process 0.862700 32542 sulfiredoxin activity 0.862668 3708 retinoic acid receptor activity 0.862652 7346 regulation of mitotic cell cycle 0.862641 1939 female pronucleus 0.862576 5432 calcium:sodium antiporter activity 0.862576 21516 dorsal spinal cord development 0.862574 33919 glucan 1,3-alpha-glucosidase activity 0.862524 16080 synaptic vesicle targeting 0.862493 46539 histamine N-methyltransferase activity 0.862475 30 mannosyltransferase activity 0.862460 32956 regulation of actin cytoskeleton organization 0.862356 15019 heparan-alpha-glucosaminide N-acetyltransferase activity 0.862330 5275 amine transmembrane transporter activity 0.862319 421 autophagic vacuole membrane 0.862262 9790 embryonic development 0.862217 45859 regulation of protein kinase activity 0.862152 8467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity 0.862140 1604 urotensin II receptor activity 0.862137 43254 regulation of protein complex assembly 0.862107 7161 calcium-independent cell-matrix adhesion 0.862089 5010 insulin-like growth factor receptor activity 0.862060 48646 anatomical structure formation involved in morphogenesis 0.861938 3875 ADP-ribosylarginine hydrolase activity 0.861889 51725 protein amino acid de-ADP-ribosylation 0.861889 4478 methionine adenosyltransferase activity 0.861817 3883 CTP synthase activity 0.861817 815 ESCRT III complex 0.861793 16780 phosphotransferase activity, for other substituted phosphate groups 0.861790 9891 positive regulation of biosynthetic process 0.861749 17090 meprin A complex 0.861703 43681 protein targeting to mitochondrion 0.861660 31570 DNA integrity checkpoint 0.861631 7007 inner mitochondrial membrane organization 0.861617 170 sphingosine hydroxylase activity 0.861606 5688 U6 snRNP 0.861558 30165 PDZ domain binding 0.861547 16574 histone ubiquitination 0.861535 46320 regulation of fatty acid oxidation 0.861525 10853 cyclase activator activity 0.861492 30250 guanylate cyclase activator activity 0.861492 32990 cell part morphogenesis 0.861492 31428 box C/D snoRNP complex 0.861429 16075 rRNA catabolic process 0.861367 4454 ketohexokinase activity 0.861365 6514 protein deubiquitination 0.861364 7499 ectoderm and mesoderm interaction 0.861316 8523 sodium-dependent multivitamin transmembrane transporter activity 0.861285 16409 palmitoyltransferase activity 0.861271 8897 holo-[acyl-carrier-protein] synthase activity 0.861268 5146 leukemia inhibitory factor receptor binding 0.861237 77 DNA damage checkpoint 0.861223 4944 C5a anaphylatoxin receptor activity 0.861213 16591 DNA-directed RNA polymerase II, holoenzyme 0.861212 2021 response to dietary excess 0.861193 5798 Golgi-associated vesicle 0.861187 5519 cytoskeletal regulatory protein binding 0.861123 42633 hair cycle 0.861027 50772 positive regulation of axonogenesis 0.861023 8625 induction of apoptosis via death domain receptors 0.860998 4523 ribonuclease H activity 0.860961 7507 heart development 0.860936 45162 clustering of voltage-gated sodium channels 0.860933 8812 choline dehydrogenase activity 0.860930 6469 negative regulation of protein kinase activity 0.860903 6290 pyrimidine dimer repair 0.860886 42589 zymogen granule membrane 0.860884 16909 SAP kinase activity 0.860864 8460 dTDP-glucose 4,6-dehydratase activity 0.860833 35282 segmentation 0.860822 51300 spindle pole body organization 0.860813 43457 regulation of cellular respiration 0.860788 6650 glycerophospholipid metabolic process 0.860764 15055 secretin receptor activity 0.860737 45786 negative regulation of cell cycle 0.860700 48037 cofactor binding 0.860654 30372 high molecular weight B cell growth factor receptor binding 0.860640 43549 regulation of kinase activity 0.860612 8321 Ral guanyl-nucleotide exchange factor activity 0.860592 47749 cholestanetriol 26-monooxygenase activity 0.860585 5279 amine transmembrane transporter activity 0.860533 30317 sperm motility 0.860510 4359 glutaminase activity 0.860440 6112 energy reserve metabolic process 0.860426 30014 CCR4-NOT complex 0.860399 43507 positive regulation of JUN kinase activity 0.860383 32924 activin receptor signaling pathway 0.860379 48024 regulation of nuclear mRNA splicing, via spliceosome 0.860367 10390 histone monoubiquitination 0.860345 4875 complement receptor activity 0.860305 47134 protein-disulfide reductase activity 0.860199 31328 positive regulation of cellular biosynthetic process 0.860184 42101 T cell receptor complex 0.860184 16876 ligase activity, forming aminoacyl-tRNA and related compounds 0.860179 16875 ligase activity, forming carbon-oxygen bonds 0.860179 4812 aminoacyl-tRNA ligase activity 0.860179 5956 protein kinase CK2 complex 0.859964 8967 phosphoglycolate phosphatase activity 0.859937 8670 2,4-dienoyl-CoA reductase (NADPH) activity 0.859933 5898 interleukin-13 receptor complex 0.859916 5873 plus-end kinesin complex 0.859837 51216 cartilage development 0.859836 45322 unmethylated CpG binding 0.859819 55069 zinc ion homeostasis 0.859812 5144 interleukin-13 receptor binding 0.859723 31624 ubiquitin conjugating enzyme binding 0.859675 9152 purine ribonucleotide biosynthetic process 0.859654 354 cis assembly of pre-catalytic spliceosome 0.859644 43086 negative regulation of catalytic activity 0.859638 19725 cellular homeostasis 0.859561 5000 vasopressin receptor activity 0.859512 33673 negative regulation of kinase activity 0.859485 47800 cysteamine dioxygenase activity 0.859457 3834 beta-carotene 15,15'-monooxygenase activity 0.859457 8112 nicotinamide N-methyltransferase activity 0.859385 31593 polyubiquitin binding 0.859331 30672 synaptic vesicle membrane 0.859314 3002 regionalization 0.859262 30044 negative regulation of actin filament depolymerization 0.859255 51693 actin filament capping 0.859255 8518 reduced folate carrier activity 0.859111 30362 protein phosphatase type 4 regulator activity 0.858854 31333 negative regulation of protein complex assembly 0.858817 30071 regulation of mitotic metaphase/anaphase transition 0.858746 8013 beta-catenin binding 0.858693 7257 activation of JUN kinase activity 0.858645 19900 kinase binding 0.858607 7179 transforming growth factor beta receptor signaling pathway 0.858509 4802 transketolase activity 0.858454 30215 semaphorin receptor binding 0.858436 43073 germ cell nucleus 0.858409 9141 nucleoside triphosphate metabolic process 0.858372 6685 sphingomyelin catabolic process 0.858314 34088 maintenance of mitotic sister chromatid cohesion 0.858293 34086 maintenance of sister chromatid cohesion 0.858293 4594 pantothenate kinase activity 0.858278 6477 protein amino acid sulfation 0.858256 51923 sulfation 0.858256 43025 cell soma 0.858192 33523 histone H2B ubiquitination 0.858190 8413 8-oxo-7,8-dihydroguanine triphosphatase activity 0.858129 16922 ligand-dependent nuclear receptor binding 0.858073 33269 internode region of axon 0.858050 1892 embryonic placenta development 0.858036 4300 enoyl-CoA hydratase activity 0.858023 48268 clathrin coat assembly 0.857947 45445 myoblast differentiation 0.857903 8494 translation activator activity 0.857854 4032 aldehyde reductase activity 0.857759 60590 ATPase regulator activity 0.857731 1517 N-acetylglucosamine 6-O-sulfotransferase activity 0.857725 30424 axon 0.857723 1948 glycoprotein binding 0.857708 30934 anchoring collagen 0.857693 5402 cation:sugar symporter activity 0.857659 5351 sugar:hydrogen symporter activity 0.857659 32579 apical lamina of hyaline layer 0.857646 16681 oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor 0.857571 16679 oxidoreductase activity, acting on diphenols and related substances as donors 0.857571 8121 ubiquinol-cytochrome-c reductase activity 0.857571 5588 collagen type V 0.857552 5854 nascent polypeptide-associated complex 0.857550 9103 lipopolysaccharide biosynthetic process 0.857509 33119 negative regulation of RNA splicing 0.857469 1736 establishment of planar polarity 0.857469 42384 cilium assembly 0.857289 4634 phosphopyruvate hydratase activity 0.857246 15 phosphopyruvate hydratase complex 0.857246 4011 DNA-dependent ATPase activity 0.857167 4970 ionotropic glutamate receptor activity 0.857127 43020 NADPH oxidase complex 0.857114 80 G1 phase of mitotic cell cycle 0.857087 32147 activation of protein kinase activity 0.857041 8199 ferric iron binding 0.857037 42393 histone binding 0.856975 6458 'de novo' protein folding 0.856967 30168 platelet activation 0.856965 30380 interleukin-17E receptor binding 0.856922 32045 guanyl-nucleotide exchange factor complex 0.856908 70053 thrombospondin receptor activity 0.856877 47045 testosterone 17-beta-dehydrogenase (NADP+) activity 0.856876 30305 heparanase activity 0.856874 33925 mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity 0.856826 6338 chromatin remodeling 0.856810 7015 actin filament organization 0.856777 3994 aconitate hydratase activity 0.856770 16847 1-aminocyclopropane-1-carboxylate synthase activity 0.856759 70773 protein N-terminal glutamine amidohydrolase activity 0.856729 18685 alkane 1-monooxygenase activity 0.856698 1594 trace-amine receptor activity 0.856681 50613 delta14-sterol reductase activity 0.856625 51325 interphase 0.856625 18738 S-formylglutathione hydrolase activity 0.856584 30748 amine N-methyltransferase activity 0.856488 16505 apoptotic protease activator activity 0.856468 47522 15-oxoprostaglandin 13-oxidase activity 0.856456 48011 nerve growth factor receptor signaling pathway 0.856411 4602 glutathione peroxidase activity 0.856411 50662 coenzyme binding 0.856391 45944 positive regulation of transcription from RNA polymerase II promoter 0.856384 1757 somite specification 0.856346 3837 beta-ureidopropionase activity 0.856343 32133 chromosome passenger complex 0.856216 34045 pre-autophagosomal structure membrane 0.856200 48096 chromatin-mediated maintenance of transcription 0.856189 4845 uracil phosphoribosyltransferase activity 0.856150 4692 cGMP-dependent protein kinase activity 0.856143 19987 negative regulation of anti-apoptosis 0.856120 30326 embryonic limb morphogenesis 0.856098 35113 embryonic appendage morphogenesis 0.856098 318 protein-methionine-R-oxide reductase activity 0.856055 30218 erythrocyte differentiation 0.856033 16524 latrotoxin receptor activity 0.856005 18212 peptidyl-tyrosine modification 0.855932 47560 3-dehydrosphinganine reductase activity 0.855908 10861 thyroid hormone receptor activator activity 0.855903 30375 thyroid hormone receptor coactivator activity 0.855903 45576 mast cell activation 0.855841 65009 regulation of molecular function 0.855822 31123 RNA 3'-end processing 0.855722 8610 lipid biosynthetic process 0.855702 16605 PML body 0.855696 6384 transcription initiation from RNA polymerase III promoter 0.855685 6122 mitochondrial electron transport, ubiquinol to cytochrome c 0.855571 48645 organ formation 0.855492 8887 glycerate kinase activity 0.855473 3980 UDP-glucose:glycoprotein glucosyltransferase activity 0.855466 34199 activation of protein kinase A activity 0.855447 51865 protein autoubiquitination 0.855447 15103 inorganic anion transmembrane transporter activity 0.855363 45668 negative regulation of osteoblast differentiation 0.855250 16458 gene silencing 0.855166 5232 serotonin-activated cation-selective channel activity 0.855128 176 nuclear exosome (RNase complex) 0.855089 50571 1,5-anhydro-D-fructose reductase activity 0.854991 30201 heparan sulfate proteoglycan metabolic process 0.854961 4449 isocitrate dehydrogenase (NAD+) activity 0.854928 48858 cell projection morphogenesis 0.854888 31983 vesicle lumen 0.854867 60205 cytoplasmic membrane-bounded vesicle lumen 0.854867 15631 tubulin binding 0.854837 16494 C-X-C chemokine receptor activity 0.854790 9144 purine nucleoside triphosphate metabolic process 0.854665 42791 5S class rRNA transcription 0.854634 42797 tRNA transcription from RNA polymerase III promoter 0.854634 127 transcription factor TFIIIC complex 0.854634 19400 alditol metabolic process 0.854616 10557 positive regulation of macromolecule biosynthetic process 0.854602 1672 regulation of chromatin assembly or disassembly 0.854535 16538 cyclin-dependent protein kinase regulator activity 0.854522 33884 phosphoethanolamine/phosphocholine phosphatase activity 0.854508 10369 chromocenter 0.854489 33038 bitter taste receptor activity 0.854478 6073 cellular glucan metabolic process 0.854477 44042 glucan metabolic process 0.854477 19935 cyclic-nucleotide-mediated signaling 0.854467 8339 MP kinase activity 0.854445 50201 fucokinase activity 0.854411 19840 isoprenoid binding 0.854398 5501 retinoid binding 0.854398 71103 DNA conformation change 0.854365 5675 holo TFIIH complex 0.854358 32870 cellular response to hormone stimulus 0.854354 71495 cellular response to endogenous stimulus 0.854354 31088 platelet dense granule membrane 0.854220 35258 steroid hormone receptor binding 0.854193 42599 lamellar body 0.854187 51864 histone demethylase activity (H3-K36 specific) 0.854172 4466 long-chain-acyl-CoA dehydrogenase activity 0.854163 16999 antibiotic metabolic process 0.854140 17000 antibiotic biosynthetic process 0.854140 6930 substrate-bound cell migration, cell extension 0.854132 4535 poly(A)-specific ribonuclease activity 0.854090 42979 ornithine decarboxylase regulator activity 0.854022 31430 M band 0.853976 50277 sedoheptulokinase activity 0.853928 16411 acylglycerol O-acyltransferase activity 0.853884 4366 glycerol-3-phosphate O-acyltransferase activity 0.853883 4997 thyrotropin-releasing hormone receptor activity 0.853880 31047 gene silencing by RNA 0.853853 60056 mammary gland involution 0.853850 9199 ribonucleoside triphosphate metabolic process 0.853833 55038 recycling endosome membrane 0.853794 1764 neuron migration 0.853790 5955 calcineurin complex 0.853678 8284 positive regulation of cell proliferation 0.853582 16926 protein desumoylation 0.853559 4632 phosphopantothenate--cysteine ligase activity 0.853542 8768 UDP-sugar diphosphatase activity 0.853445 5388 calcium-transporting ATPase activity 0.853432 9584 detection of visible light 0.853400 43954 cellular component maintenance 0.853345 7029 endoplasmic reticulum organization 0.853323 9205 purine ribonucleoside triphosphate metabolic process 0.853302 8034 lipoprotein binding 0.853289 19901 protein kinase binding 0.853226 70695 FHF complex 0.853156 381 regulation of alternative nuclear mRNA splicing, via spliceosome 0.853141 60548 negative regulation of cell death 0.853139 43069 negative regulation of programmed cell death 0.853139 8190 eukaryotic initiation factor 4E binding 0.853098 47750 cholestenol delta-isomerase activity 0.852907 922 spindle pole 0.852822 3945 N-acetyllactosamine synthase activity 0.852808 46922 peptide-O-fucosyltransferase activity 0.852762 3997 acyl-CoA oxidase activity 0.852676 18108 peptidyl-tyrosine phosphorylation 0.852647 42272 nuclear RNA export factor complex 0.852578 45926 negative regulation of growth 0.852572 30384 phosphoinositide metabolic process 0.852561 6518 peptide metabolic process 0.852529 50912 detection of chemical stimulus involved in sensory perception of taste 0.852506 5641 nuclear envelope lumen 0.852499 51246 regulation of protein metabolic process 0.852495 43072 negative regulation of programmed cell death 0.852480 6515 misfolded or incompletely synthesized protein catabolic process 0.852480 4421 hydroxymethylglutaryl-CoA synthase activity 0.852472 43967 histone H4 acetylation 0.852313 15849 organic acid transport 0.852272 30091 protein repair 0.852229 44460 flagellum part 0.852152 44442 microtubule-based flagellum part 0.852152 31235 intrinsic to internal side of plasma membrane 0.852143 7187 G-protein signaling, coupled to cyclic nucleotide second messenger 0.852121 43066 negative regulation of apoptosis 0.852105 8173 RNA methyltransferase activity 0.852095 3679 DNA helicase activity 0.852073 6818 hydrogen transport 0.851972 31301 integral to organelle membrane 0.851962 30331 estrogen receptor binding 0.851894 7389 pattern specification process 0.851833 19842 vitamin binding 0.851723 32535 regulation of cellular component size 0.851638 51299 centrosome separation 0.851589 15917 aminophospholipid transport 0.851564 15114 phosphate transmembrane transporter activity 0.851550 8017 microtubule binding 0.851503 30176 integral to endoplasmic reticulum membrane 0.851460 3868 4-hydroxyphenylpyruvate dioxygenase activity 0.851458 2253 activation of immune response 0.851422 801 central element 0.851371 46942 carboxylic acid transport 0.851349 16684 oxidoreductase activity, acting on peroxide as acceptor 0.851317 4601 peroxidase activity 0.851317 6750 glutathione biosynthetic process 0.851184 42375 quinone cofactor metabolic process 0.851008 4718 Janus kinase activity 0.850997 90 mitotic anaphase 0.850995 51322 anaphase 0.850995 5977 glycogen metabolic process 0.850984 6884 cell volume homeostasis 0.850950 16888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 0.850908 15144 carbohydrate transmembrane transporter activity 0.850833 33176 proton-transporting V-type ATPase complex 0.850689 16471 vacuolar proton-transporting V-type ATPase complex 0.850689 18125 peptidyl-cysteine methylation 0.850686 48705 skeletal system morphogenesis 0.850666 1727 lipid kinase activity 0.850655 16829 lyase activity 0.850614 5672 transcription factor TFIIA complex 0.850575 51173 positive regulation of nitrogen compound metabolic process 0.850558 4791 thioredoxin-disulfide reductase activity 0.850538 6360 transcription from RNA polymerase I promoter 0.850501 33180 proton-transporting V-type ATPase, V1 domain 0.850496 6398 histone mRNA 3'-end processing 0.850444 4596 peptide alpha-N-acetyltransferase activity 0.850373 34212 peptide N-acetyltransferase activity 0.850373 32271 regulation of protein polymerization 0.850351 8091 spectrin 0.850335 70 mitotic sister chromatid segregation 0.850230 15082 di-, tri-valent inorganic cation transmembrane transporter activity 0.850183 43508 negative regulation of JUN kinase activity 0.850179 9913 epidermal cell differentiation 0.850178 7220 Notch receptor processing 0.850158 15837 amine transport 0.850111 32272 negative regulation of protein polymerization 0.850018 9880 embryonic pattern specification 0.849946 32422 purine-rich negative regulatory element binding 0.849913 7259 JAK-STAT cascade 0.849900 7216 metabotropic glutamate receptor signaling pathway 0.849863 8054 cyclin catabolic process 0.849826 15992 proton transport 0.849765 46915 transition metal ion transmembrane transporter activity 0.849748 4740 pyruvate dehydrogenase (acetyl-transferring) kinase activity 0.849561 300 peripheral to membrane of membrane fraction 0.849552 33017 sarcoplasmic reticulum membrane 0.849447 4716 receptor signaling protein tyrosine kinase activity 0.849200 5542 folic acid binding 0.849168 50872 white fat cell differentiation 0.849111 8634 negative regulation of survival gene product expression 0.849063 4331 fructose-2,6-bisphosphate 2-phosphatase activity 0.849028 43022 ribosome binding 0.848949 31300 intrinsic to organelle membrane 0.848927 15858 nucleoside transport 0.848862 3727 single-stranded RNA binding 0.848737 15272 ATP-activated inward rectifier potassium channel activity 0.848727 4003 ATP-dependent DNA helicase activity 0.848640 43010 camera-type eye development 0.848584 42460 eye development 0.848584 5372 water transporter activity 0.848508 9266 response to temperature stimulus 0.848467 6071 glycerol metabolic process 0.848397 8417 fucosyltransferase activity 0.848394 19754 one-carbon metabolic process 0.848249 19753 one-carbon metabolic process 0.848249 43186 P granule 0.848226 31229 intrinsic to nuclear inner membrane 0.848211 44453 nuclear membrane part 0.848211 5639 integral to nuclear inner membrane 0.848211 17112 Rab guanyl-nucleotide exchange factor activity 0.848183 5796 Golgi lumen 0.848150 44464 cell part 0.848148 4991 parathyroid hormone receptor activity 0.848126 22604 regulation of cell morphogenesis 0.848082 8290 F-actin capping protein complex 0.848069 4614 phosphoglucomutase activity 0.847910 9142 nucleoside triphosphate biosynthetic process 0.847796 9201 ribonucleoside triphosphate biosynthetic process 0.847796 51119 sugar transmembrane transporter activity 0.847781 30259 lipid glycosylation 0.847747 5861 troponin complex 0.847654 6665 sphingolipid metabolic process 0.847642 6758 ATP biosynthetic process 0.847624 15986 ATP synthesis coupled proton transport 0.847624 15985 energy coupled proton transport, down electrochemical gradient 0.847624 5975 carbohydrate metabolic process 0.847541 4605 phosphatidate cytidylyltransferase activity 0.847450 819 sister chromatid segregation 0.847448 4658 propionyl-CoA carboxylase activity 0.847378 5234 extracellular-glutamate-gated ion channel activity 0.847299 5881 cytoplasmic microtubule 0.847295 5062 hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity 0.847284 16566 specific transcriptional repressor activity 0.847263 910 cytokinesis 0.847233 8757 S-adenosylmethionine-dependent methyltransferase activity 0.847232 45935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 0.847230 48608 reproductive structure development 0.847200 6621 protein retention in ER lumen 0.847195 16884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor 0.847159 9145 purine nucleoside triphosphate biosynthetic process 0.847137 9206 purine ribonucleoside triphosphate biosynthetic process 0.847137 33130 acetylcholine receptor binding 0.847088 164 protein phosphatase type 1 complex 0.847008 43124 negative regulation of I-kappaB kinase/NF-kappaB cascade 0.846995 74 regulation of cell cycle 0.846989 6182 cGMP biosynthetic process 0.846964 6261 DNA-dependent DNA replication 0.846881 8187 poly-pyrimidine tract binding 0.846865 17025 TATA-binding protein binding 0.846704 48812 neuron projection morphogenesis 0.846681 16891 endoribonuclease activity, producing 5'-phosphomonoesters 0.846595 30169 low-density lipoprotein binding 0.846581 5342 organic acid transmembrane transporter activity 0.846545 347 THO complex 0.846520 445 THO complex part of transcription export complex 0.846520 30837 negative regulation of actin filament polymerization 0.846505 50790 regulation of catalytic activity 0.846459 30031 cell projection assembly 0.846394 3785 actin monomer binding 0.846361 30510 regulation of BMP signaling pathway 0.846323 50840 extracellular matrix binding 0.846299 5123 death receptor binding 0.846255 12506 vesicle membrane 0.846237 46068 cGMP metabolic process 0.846155 8384 IkappaB kinase activity 0.846123 50681 androgen receptor binding 0.846115 30666 endocytic vesicle membrane 0.846091 4618 phosphoglycerate kinase activity 0.846074 4046 aminoacylase activity 0.846028 6633 fatty acid biosynthetic process 0.845963 45494 photoreceptor cell maintenance 0.845962 15057 thrombin receptor activity 0.845931 15171 amino acid transmembrane transporter activity 0.845856 30182 neuron differentiation 0.845769 8094 DNA-dependent ATPase activity 0.845749 31093 platelet alpha granule lumen 0.845727 16291 acyl-CoA thioesterase activity 0.845702 44255 cellular lipid metabolic process 0.845650 7051 spindle organization 0.845615 16671 oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor 0.845606 48511 rhythmic process 0.845600 42581 specific granule 0.845599 33872 [heparan sulfate]-glucosamine 3-sulfotransferase 3 activity 0.845519 46834 lipid phosphorylation 0.845456 9408 response to heat 0.845451 51539 4 iron, 4 sulfur cluster binding 0.845415 12 single strand break repair 0.845405 44086 vacuole organization 0.845355 43355 epidermal cell differentiation 0.845337 75 cell cycle checkpoint 0.845302 7034 vacuolar transport 0.845260 46943 carboxylic acid transmembrane transporter activity 0.845180 22406 membrane docking 0.845163 8272 sulfate transport 0.845154 32947 protein complex scaffold 0.845091 90101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 0.845086 35092 sperm chromatin condensation 0.845060 4974 leukotriene receptor activity 0.845033 16576 histone dephosphorylation 0.845012 48038 quinone binding 0.844998 6857 oligopeptide transport 0.844975 16705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 0.844950 4457 lactate dehydrogenase activity 0.844877 5092 GDP-dissociation inhibitor activity 0.844829 5791 rough endoplasmic reticulum 0.844716 10627 regulation of protein kinase cascade 0.844711 16255 attachment of GPI anchor to protein 0.844550 19789 SUMO ligase activity 0.844545 51254 positive regulation of RNA metabolic process 0.844530 16893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 0.844497 6822 anion transport 0.844473 48519 negative regulation of biological process 0.844467 43118 negative regulation of biological process 0.844467 239 pachytene 0.844456 6631 fatty acid metabolic process 0.844347 4706 JUN kinase kinase kinase activity 0.844336 5042 netrin receptor activity 0.844336 46784 intronless viral mRNA export from host nucleus 0.844333 19478 D-amino acid catabolic process 0.844311 16572 histone phosphorylation 0.844256 8037 cell recognition 0.844240 16997 alpha-sialidase activity 0.844224 4308 exo-alpha-sialidase activity 0.844224 17162 aryl hydrocarbon receptor binding 0.844207 5048 signal sequence binding 0.844194 30496 midbody 0.844076 8227 G-protein coupled amine receptor activity 0.844067 5876 spindle microtubule 0.844017 10941 regulation of cell death 0.843949 4828 serine-tRNA ligase activity 0.843922 6434 seryl-tRNA aminoacylation 0.843922 5849 mRNA cleavage factor complex 0.843901 46034 ATP metabolic process 0.843831 70265 necrotic cell death 0.843828 3913 DNA photolyase activity 0.843708 16896 exoribonuclease activity, producing 5'-phosphomonoesters 0.843667 4532 exoribonuclease activity 0.843667 3981 glucuronosyltransferase activity 0.843663 45893 positive regulation of transcription, DNA-dependent 0.843663 43070 regulation of programmed cell death 0.843621 43067 regulation of programmed cell death 0.843621 16706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors 0.843530 8525 phosphatidylcholine transmembrane transporter activity 0.843515 7140 male meiosis 0.843372 8505 monocarboxylic acid transmembrane transporter activity 0.843280 42625 ATPase activity, coupled to transmembrane movement of ions 0.843260 45177 apical part of cell 0.843255 31023 microtubule organizing center organization 0.843239 30866 cortical actin cytoskeleton organization 0.843218 6643 membrane lipid metabolic process 0.843208 4712 protein serine/threonine/tyrosine kinase activity 0.843207 16810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 0.843183 51059 NF-kappaB binding 0.843171 5080 protein kinase C binding 0.843161 8113 peptide-methionine-(S)-S-oxide reductase activity 0.843137 31625 ubiquitin protein ligase binding 0.843081 30371 translation repressor activity 0.843039 16800 hydrolase activity, hydrolyzing O-glycosyl compounds 0.843034 5658 alpha DNA polymerase:primase complex 0.843034 4803 transposase activity 0.843000 51019 mitogen-activated protein kinase binding 0.843000 153 cytoplasmic ubiquitin ligase complex 0.842968 8654 phospholipid biosynthetic process 0.842959 44438 microbody part 0.842899 44439 peroxisomal part 0.842899 794 condensed nuclear chromosome 0.842883 7173 epidermal growth factor receptor signaling pathway 0.842883 51726 regulation of cell cycle 0.842875 30030 cell projection organization 0.842761 16324 apical plasma membrane 0.842728 1602 pancreatic polypeptide receptor activity 0.842726 15884 folic acid transport 0.842666 42153 RPTP-like protein binding 0.842645 43407 negative regulation of MAP kinase activity 0.842636 16627 oxidoreductase activity, acting on the CH-CH group of donors 0.842628 43015 gamma-tubulin binding 0.842618 30659 cytoplasmic vesicle membrane 0.842580 9451 RNA modification 0.842538 22626 cytosolic ribosome 0.842356 45120 pronucleus 0.842310 42981 regulation of apoptosis 0.842298 15145 monosaccharide transmembrane transporter activity 0.842242 15149 hexose transmembrane transporter activity 0.842242 43543 protein amino acid acylation 0.842178 4767 sphingomyelin phosphodiesterase activity 0.842114 10942 positive regulation of cell death 0.842038 16547 RNA modification 0.841981 16556 mRNA modification 0.841873 4859 phospholipase inhibitor activity 0.841854 30228 lipoprotein receptor activity 0.841847 226 microtubule cytoskeleton organization 0.841791 8023 transcription elongation factor complex 0.841768 1654 eye development 0.841622 8202 steroid metabolic process 0.841616 42624 ATPase activity, uncoupled 0.841607 7618 mating 0.841607 15385 sodium:hydrogen antiporter activity 0.841564 5451 monovalent cation:hydrogen antiporter activity 0.841564 4996 thyroid-stimulating hormone receptor activity 0.841535 9799 determination of symmetry 0.841387 9855 determination of bilateral symmetry 0.841387 7368 determination of left/right symmetry 0.841387 8298 intracellular mRNA localization 0.841374 6403 RNA localization 0.841374 31929 TOR signaling pathway 0.841358 4127 cytidylate kinase activity 0.841342 6904 vesicle docking during exocytosis 0.841270 9582 detection of abiotic stimulus 0.841269 3012 muscle system process 0.841230 30041 actin filament polymerization 0.841146 9952 anterior/posterior pattern formation 0.841139 7178 transmembrane receptor protein serine/threonine kinase signaling pathway 0.841137 6491 N-glycan processing 0.841119 10648 negative regulation of cell communication 0.840978 30276 clathrin binding 0.840957 43068 positive regulation of programmed cell death 0.840949 4165 dodecenoyl-CoA delta-isomerase activity 0.840746 2226 innate immune response 0.840706 43071 positive regulation of programmed cell death 0.840654 3906 DNA-(apurinic or apyrimidinic site) lyase activity 0.840625 346 transcription export complex 0.840521 6898 receptor-mediated endocytosis 0.840487 5149 interleukin-1 receptor binding 0.840486 7033 vacuole organization 0.840472 30433 ER-associated protein catabolic process 0.840464 46854 phosphoinositide phosphorylation 0.840425 19966 interleukin-1 binding 0.840411 8089 anterograde axon cargo transport 0.840386 5035 death receptor activity 0.840382 30346 protein phosphatase 2B binding 0.840376 19903 protein phosphatase binding 0.840326 4886 retinoid-X receptor activity 0.840314 43065 positive regulation of apoptosis 0.840232 30032 lamellipodium assembly 0.840121 16247 channel regulator activity 0.840086 35086 flagellar axoneme 0.840038 15670 carbon dioxide transport 0.839986 4797 thymidine kinase activity 0.839845 16667 oxidoreductase activity, acting on sulfur group of donors 0.839835 7369 gastrulation 0.839813 7163 establishment or maintenance of cell polarity 0.839651 17166 vinculin binding 0.839547 51297 centrosome organization 0.839402 35098 ESC/E(Z) complex 0.839337 31124 mRNA 3'-end processing 0.839258 7610 behavior 0.839204 31573 intra-S DNA damage checkpoint 0.839189 4480 methyltransferase activity 0.839183 31201 SNARE complex 0.839123 22890 inorganic cation transmembrane transporter activity 0.839064 8568 microtubule-severing ATPase activity 0.839044 3827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity 0.838891 6754 ATP biosynthetic process 0.838881 10628 positive regulation of gene expression 0.838847 8223 flagellum 0.838847 9434 microtubule-based flagellum 0.838847 32259 methylation 0.838828 4531 deoxyribonuclease II activity 0.838806 6928 cellular component movement 0.838771 1675 acrosome assembly 0.838766 48531 beta-1,3-galactosyltransferase activity 0.838762 8064 regulation of actin polymerization or depolymerization 0.838706 47485 protein N-terminus binding 0.838598 6878 cellular copper ion homeostasis 0.838591 5173 stem cell factor receptor binding 0.838541 42127 regulation of cell proliferation 0.838361 16584 nucleosome positioning 0.838332 279 M phase 0.838310 31227 intrinsic to endoplasmic reticulum membrane 0.838296 6820 anion transport 0.838280 16461 unconventional myosin complex 0.838167 9249 protein lipoylation 0.837972 6390 transcription from mitochondrial promoter 0.837943 5736 DNA-directed RNA polymerase I complex 0.837929 19894 kinesin binding 0.837920 6623 protein targeting to vacuole 0.837908 55037 recycling endosome 0.837877 5759 mitochondrial matrix 0.837825 4029 aldehyde dehydrogenase (NAD) activity 0.837806 30900 forebrain development 0.837744 17159 pantetheine hydrolase activity 0.837688 48704 embryonic skeletal system morphogenesis 0.837669 48278 vesicle docking 0.837627 51781 positive regulation of cell division 0.837607 17040 ceramidase activity 0.837588 43043 peptide biosynthetic process 0.837586 16573 histone acetylation 0.837557 30159 receptor signaling complex scaffold activity 0.837535 30111 regulation of Wnt receptor signaling pathway 0.837449 8406 gonad development 0.837382 43966 histone H3 acetylation 0.837339 17091 AU-rich element binding 0.837318 6975 DNA damage induced protein phosphorylation 0.837309 32403 protein complex binding 0.837084 30522 intracellular receptor-mediated signaling pathway 0.837070 6298 mismatch repair 0.837053 5546 phosphatidylinositol-4,5-bisphosphate binding 0.837018 40011 locomotion 0.836937 8332 low voltage-gated calcium channel activity 0.836915 87 M phase of mitotic cell cycle 0.836899 44455 mitochondrial membrane part 0.836878 1756 somitogenesis 0.836842 7585 respiratory gaseous exchange 0.836799 4568 chitinase activity 0.836773 6030 chitin metabolic process 0.836773 6032 chitin catabolic process 0.836773 45039 protein import into mitochondrial inner membrane 0.836763 42719 mitochondrial intermembrane space protein transporter complex 0.836763 6358 regulation of transcription from RNA polymerase II promoter, global 0.836581 4814 arginine-tRNA ligase activity 0.836569 6420 arginyl-tRNA aminoacylation 0.836569 50897 cobalt ion binding 0.836369 4829 threonine-tRNA ligase activity 0.836344 6435 threonyl-tRNA aminoacylation 0.836344 51302 regulation of cell division 0.836283 5548 phospholipid transporter activity 0.836280 7172 signal complex assembly 0.836242 43088 regulation of Cdc42 GTPase activity 0.836224 4938 alpha2-adrenergic receptor activity 0.836223 48523 negative regulation of cellular process 0.836217 51243 negative regulation of cellular process 0.836217 45941 positive regulation of transcription 0.836041 4690 cyclic nucleotide-dependent protein kinase activity 0.835875 44433 cytoplasmic vesicle part 0.835769 15298 solute:cation antiporter activity 0.835746 19637 organophosphate metabolic process 0.835732 42472 inner ear morphogenesis 0.835678 16641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 0.835669 51427 hormone receptor binding 0.835658 16593 Cdc73/Paf1 complex 0.835615 9395 phospholipid catabolic process 0.835592 6323 DNA packaging 0.835586 15889 cobalamin transport 0.835495 5594 collagen type IX 0.835337 18345 protein palmitoylation 0.835334 6473 protein amino acid acetylation 0.835227 30261 chromosome condensation 0.835221 1674 female germ cell nucleus 0.835209 17077 oxidative phosphorylation uncoupler activity 0.835209 31970 organelle envelope lumen 0.835139 16601 Rac protein signal transduction 0.835103 3953 NAD+ nucleosidase activity 0.834943 15301 anion:anion antiporter activity 0.834940 6825 copper ion transport 0.834849 8020 G-protein coupled photoreceptor activity 0.834765 7023 post-chaperonin tubulin folding pathway 0.834726 48513 organ development 0.834711 4033 aldo-keto reductase activity 0.834652 30865 cortical cytoskeleton organization 0.834614 5328 neurotransmitter:sodium symporter activity 0.834612 4910 interleukin-1, Type II, blocking receptor activity 0.834605 30345 structural constituent of tooth enamel 0.834509 30021 extracellular matrix structural constituent conferring compression resistance 0.834509 15300 solute:solute antiporter activity 0.834489 4549 tRNA-specific ribonuclease activity 0.834449 4708 MAP kinase kinase activity 0.834436 3690 double-stranded DNA binding 0.834436 8240 tripeptidyl-peptidase activity 0.834436 8038 neuron recognition 0.834388 43120 tumor necrosis factor binding 0.834243 6091 generation of precursor metabolites and energy 0.834230 6445 regulation of translation 0.834196 5504 fatty acid binding 0.834189 5436 sodium:phosphate symporter activity 0.834159 30308 negative regulation of cell growth 0.834117 5640 nuclear outer membrane 0.834105 19206 nucleoside kinase activity 0.834071 50660 FAD binding 0.834062 9988 cell-cell recognition 0.834039 22904 respiratory electron transport chain 0.834036 3705 RNA polymerase II transcription factor activity, enhancer binding 0.833986 130 transcription factor activity 0.833986 5859 muscle myosin complex 0.833908 9605 response to external stimulus 0.833877 9968 negative regulation of signal transduction 0.833794 51017 actin filament bundle formation 0.833770 8499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity 0.833748 30833 regulation of actin filament polymerization 0.833745 7623 circadian rhythm 0.833740 4439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 0.833683 34595 phosphoinositide 5-phosphatase activity 0.833683 9306 protein secretion 0.833643 51087 chaperone binding 0.833618 19899 enzyme binding 0.833560 30832 regulation of actin filament length 0.833548 5802 trans-Golgi network 0.833490 16520 growth hormone-releasing hormone receptor activity 0.833333 8428 ribonuclease inhibitor activity 0.833108 4702 receptor signaling protein serine/threonine kinase activity 0.833075 51604 protein maturation 0.833074 4735 pyrroline-5-carboxylate reductase activity 0.833007 8066 glutamate receptor activity 0.832995 70717 poly-purine tract binding 0.832993 34483 heparan sulfate sulfotransferase activity 0.832956 1906 cell killing 0.832913 48013 ephrin receptor signaling pathway 0.832891 16775 phosphotransferase activity, nitrogenous group as acceptor 0.832879 5078 MAP-kinase scaffold activity 0.832842 43005 neuron projection 0.832836 45426 quinone cofactor biosynthetic process 0.832762 6744 ubiquinone biosynthetic process 0.832762 6743 ubiquinone metabolic process 0.832762 4428 inositol or phosphatidylinositol kinase activity 0.832735 6612 protein targeting to membrane 0.832713 15698 inorganic anion transport 0.832686 31013 troponin I binding 0.832610 9887 organ morphogenesis 0.832581 3696 satellite DNA binding 0.832536 175 3'-5'-exoribonuclease activity 0.832473 16778 diphosphotransferase activity 0.832472 42169 SH2 domain binding 0.832423 6644 phospholipid metabolic process 0.832369 16717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 0.832295 30275 LRR domain binding 0.832214 8154 actin polymerization or depolymerization 0.832152 18196 peptidyl-asparagine modification 0.832097 18279 protein amino acid N-linked glycosylation via asparagine 0.832097 50682 AF-2 domain binding 0.832046 45026 plasma membrane fusion 0.831959 42056 chemoattractant activity 0.831908 4576 oligosaccharyl transferase activity 0.831797 288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 0.831563 1580 detection of chemical stimulus involved in sensory perception of bitter taste 0.831442 30216 keratinocyte differentiation 0.831373 5758 mitochondrial intermembrane space 0.831357 31903 microbody membrane 0.831281 5778 peroxisomal membrane 0.831281 5049 nuclear export signal receptor activity 0.831184 15081 sodium ion transmembrane transporter activity 0.831181 30056 hemidesmosome 0.831136 8139 nuclear localization sequence binding 0.831053 10811 positive regulation of cell-substrate adhesion 0.830984 16972 thiol oxidase activity 0.830814 5770 late endosome 0.830785 30173 integral to Golgi membrane 0.830739 51716 cellular response to stimulus 0.830710 17034 Rap guanyl-nucleotide exchange factor activity 0.830645 16651 oxidoreductase activity, acting on NADH or NADPH 0.830479 51540 metal cluster binding 0.830403 51536 iron-sulfur cluster binding 0.830403 6379 mRNA cleavage 0.830339 44450 microtubule organizing center part 0.830307 4559 alpha-mannosidase activity 0.830290 4437 inositol or phosphatidylinositol phosphatase activity 0.830286 43566 structure-specific DNA binding 0.830263 3963 RNA-3'-phosphate cyclase activity 0.830259 7020 microtubule nucleation 0.830245 6730 one-carbon metabolic process 0.830201 17154 semaphorin receptor activity 0.830162 4704 NF-kappaB-inducing kinase activity 0.830118 5904 plasma membrane 0.830111 42383 sarcolemma 0.830111 4691 cAMP-dependent protein kinase activity 0.830018 4977 melanocortin receptor activity 0.829983 9892 negative regulation of metabolic process 0.829982 5326 neurotransmitter transporter activity 0.829977 7635 chemosensory behavior 0.829976 31228 intrinsic to Golgi membrane 0.829841 51537 2 iron, 2 sulfur cluster binding 0.829815 50733 RS domain binding 0.829800 7409 axonogenesis 0.829790 15077 monovalent inorganic cation transmembrane transporter activity 0.829758 15078 hydrogen ion transmembrane transporter activity 0.829750 32813 tumor necrosis factor receptor superfamily binding 0.829740 51015 actin filament binding 0.829678 3960 NADPH:quinone reductase activity 0.829607 30427 site of polarized growth 0.829584 30426 growth cone 0.829584 30483 site of polarized growth 0.829584 134 site of polarized growth 0.829584 32525 somite rostral/caudal axis specification 0.829583 1750 photoreceptor outer segment 0.829493 19907 cyclin-dependent protein kinase activating kinase holoenzyme complex 0.829437 7043 cell-cell junction assembly 0.829341 7131 reciprocal meiotic recombination 0.829334 3701 RNA polymerase I transcription factor activity 0.829253 17056 structural constituent of nuclear pore 0.829220 3706 ligand-regulated transcription factor activity 0.829203 16802 trialkylsulfonium hydrolase activity 0.829043 4013 adenosylhomocysteinase activity 0.829043 7422 peripheral nervous system development 0.829038 30509 BMP signaling pathway 0.828968 17060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity 0.828947 8285 negative regulation of cell proliferation 0.828922 46488 phosphatidylinositol metabolic process 0.828857 30198 extracellular matrix organization 0.828805 160 two-component signal transduction system (phosphorelay) 0.828784 7217 tachykinin receptor signaling pathway 0.828730 8046 axon guidance receptor activity 0.828729 8334 histone mRNA metabolic process 0.828705 35257 nuclear hormone receptor binding 0.828643 718 nucleotide-excision repair, DNA damage removal 0.828370 46777 protein amino acid autophosphorylation 0.828353 19838 growth factor binding 0.828269 10646 regulation of cell communication 0.828201 5775 vacuolar lumen 0.828173 5518 collagen binding 0.828135 50051 leukotriene-B4 20-monooxygenase activity 0.828013 30553 cGMP binding 0.827931 19002 GMP binding 0.827931 46983 protein dimerization activity 0.827864 15662 ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism 0.827774 7598 blood coagulation, extrinsic pathway 0.827752 9653 anatomical structure morphogenesis 0.827750 48002 antigen processing and presentation of peptide antigen 0.827746 83 regulation of transcription involved in G1/S-phase of mitotic cell cycle 0.827731 15271 outward rectifier potassium channel activity 0.827695 16986 transcription initiation factor activity 0.827676 4908 interleukin-1 receptor activity 0.827658 5319 lipid transporter activity 0.827613 7127 meiosis I 0.827603 50847 progesterone receptor signaling pathway 0.827574 6936 muscle contraction 0.827544 4647 phosphoserine phosphatase activity 0.827482 7379 segment specification 0.827401 30667 secretory granule membrane 0.827350 5522 profilin binding 0.827259 795 synaptonemal complex 0.827231 8159 positive transcription elongation factor activity 0.827183 46903 secretion 0.826957 44237 cellular metabolic process 0.826910 2020 protease binding 0.826812 33177 proton-transporting two-sector ATPase complex, proton-transporting domain 0.826761 4459 L-lactate dehydrogenase activity 0.826699 19642 anaerobic glycolysis 0.826699 30914 STAGA complex 0.826562 3684 damaged DNA binding 0.826559 35272 exocrine system development 0.826492 42277 peptide binding 0.826452 19955 cytokine binding 0.826340 42730 fibrinolysis 0.826315 152 nuclear ubiquitin ligase complex 0.826294 19788 NEDD8 ligase activity 0.826246 46027 phospholipid:diacylglycerol acyltransferase activity 0.826245 8585 female gonad development 0.826168 30132 clathrin coat of coated pit 0.826168 8142 oxysterol binding 0.826130 16776 phosphotransferase activity, phosphate group as acceptor 0.826111 17121 phospholipid scrambling 0.826065 17128 phospholipid scramblase activity 0.826065 50684 regulation of mRNA processing 0.826049 15380 anion exchanger activity 0.825988 51318 G1 phase 0.825929 209 protein polyubiquitination 0.825891 30139 endocytic vesicle 0.825770 31324 negative regulation of cellular metabolic process 0.825584 19207 kinase regulator activity 0.825580 70461 SAGA-type complex 0.825519 3923 GPI-anchor transamidase activity 0.825501 42765 GPI-anchor transamidase complex 0.825501 46030 inositol trisphosphate phosphatase activity 0.825464 4445 inositol-polyphosphate 5-phosphatase activity 0.825464 51336 regulation of hydrolase activity 0.825452 5094 Rho GDP-dissociation inhibitor activity 0.825389 16460 myosin II complex 0.825327 5337 nucleoside transmembrane transporter activity 0.825289 6297 nucleotide-excision repair, DNA gap filling 0.825209 3841 1-acylglycerol-3-phosphate O-acyltransferase activity 0.825178 5496 steroid binding 0.825142 4030 aldehyde dehydrogenase [NAD(P)+] activity 0.825074 16866 intramolecular transferase activity 0.825054 5355 glucose transmembrane transporter activity 0.824967 19965 cytokine binding 0.824854 8022 protein C-terminus binding 0.824792 3006 reproductive developmental process 0.824736 16322 neuron remodeling 0.824640 42809 vitamin D receptor binding 0.824597 299 integral to membrane of membrane fraction 0.824568 16918 retinal binding 0.824536 1652 granular component 0.824407 31902 late endosome membrane 0.824335 278 mitotic cell cycle 0.824236 10740 positive regulation of protein kinase cascade 0.824188 30976 thiamin pyrophosphate binding 0.824178 9058 biosynthetic process 0.824095 16485 protein processing 0.824039 4579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity 0.824018 43492 ATPase activity, coupled to movement of substances 0.823893 3828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity 0.823831 50265 RNA uridylyltransferase activity 0.823618 123 histone acetyltransferase complex 0.823570 30017 sarcomere 0.823510 6911 phagocytosis, engulfment 0.823411 16585 chromatin remodeling complex 0.823284 35267 NuA4 histone acetyltransferase complex 0.823247 6865 amino acid transport 0.823240 9301 snRNA transcription 0.823184 5057 receptor signaling protein activity 0.823134 30518 steroid hormone receptor signaling pathway 0.823107 30514 negative regulation of BMP signaling pathway 0.823107 42626 ATPase activity, coupled to transmembrane movement of substances 0.823047 9295 nucleoid 0.823041 42645 mitochondrial nucleoid 0.823041 33276 transcription factor TFTC complex 0.822913 6947 plasma membrane fusion 0.822859 7342 fusion of sperm to egg plasma membrane 0.822859 30197 extracellular matrix constituent, lubricant activity 0.822830 8152 metabolic process 0.822718 19800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan 0.822572 30130 clathrin coat of trans-Golgi network vesicle 0.822493 4468 lysine N-acetyltransferase activity 0.822415 4402 histone acetyltransferase activity 0.822415 2526 acute inflammatory response 0.822408 5746 mitochondrial respiratory chain 0.822374 35253 ciliary rootlet 0.822275 43623 cellular protein complex assembly 0.822242 6405 RNA export from nucleus 0.822123 30137 COPI-coated vesicle 0.822105 389 nuclear mRNA 3'-splice site recognition 0.822033 16820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 0.821942 7588 excretion 0.821844 7525 somatic muscle development 0.821832 44463 cell projection part 0.821742 4966 galanin receptor activity 0.821735 55070 copper ion homeostasis 0.821691 44249 cellular biosynthetic process 0.821612 4012 phospholipid-translocating ATPase activity 0.821558 15247 aminophospholipid transporter activity 0.821558 44437 vacuolar part 0.821554 4630 phospholipase D activity 0.821503 6450 regulation of translational fidelity 0.821494 16580 Sin3 complex 0.821491 70822 Sin3-type complex 0.821491 8497 phospholipid transporter activity 0.821382 16973 poly(A)+ mRNA export from nucleus 0.821376 8330 protein tyrosine/threonine phosphatase activity 0.821308 71212 subsynaptic reticulum 0.821233 4028 3-chloroallyl aldehyde dehydrogenase activity 0.821199 6289 nucleotide-excision repair 0.821167 5674 transcription factor TFIIF complex 0.821132 16049 cell growth 0.821128 12502 induction of programmed cell death 0.821083 12503 induction of programmed cell death 0.821083 3728 single-stranded RNA binding 0.821050 10605 negative regulation of macromolecule metabolic process 0.821045 30160 GKAP/Homer scaffold activity 0.821035 4419 hydroxymethylglutaryl-CoA lyase activity 0.820987 15116 sulfate transmembrane transporter activity 0.820961 5679 chromatin remodeling complex 0.820956 8590 regulation of Wnt receptor signaling pathway 0.820943 4556 alpha-amylase activity 0.820930 16160 amylase activity 0.820930 5527 macrolide binding 0.820869 5528 FK506 binding 0.820869 45104 intermediate filament cytoskeleton organization 0.820840 8624 induction of apoptosis by extracellular signals 0.820836 42382 paraspeckles 0.820818 51605 protein maturation by peptide bond cleavage 0.820786 4745 retinol dehydrogenase activity 0.820754 4860 protein kinase inhibitor activity 0.820607 1601 peptide YY receptor activity 0.820526 51861 glycolipid binding 0.820516 8389 coumarin 7-hydroxylase activity 0.820456 6917 induction of apoptosis 0.820450 19841 retinol binding 0.820444 4566 beta-glucuronidase activity 0.820351 5884 actin filament 0.820229 7626 locomotory behavior 0.820228 16782 transferase activity, transferring sulfur-containing groups 0.820216 50510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity 0.820209 51168 nuclear export 0.820179 19887 protein kinase regulator activity 0.819999 6916 anti-apoptosis 0.819983 16492 neurotensin receptor activity, G-protein coupled 0.819973 3678 DNA helicase activity 0.819825 8353 RNA polymerase II carboxy-terminal domain kinase activity 0.819793 19205 nucleobase, nucleoside, nucleotide kinase activity 0.819752 51084 'de novo' posttranslational protein folding 0.819684 43968 histone H2A acetylation 0.819673 16307 phosphatidylinositol phosphate kinase activity 0.819640 19210 kinase inhibitor activity 0.819626 30316 osteoclast differentiation 0.819569 16323 basolateral plasma membrane 0.819554 9055 electron carrier activity 0.819552 16208 AMP binding 0.819533 46582 Rap GTPase activator activity 0.819530 16032 viral reproduction 0.819528 4467 long-chain-fatty-acid-CoA ligase activity 0.819420 15399 primary active transmembrane transporter activity 0.819413 15405 P-P-bond-hydrolysis-driven transmembrane transporter activity 0.819413 7164 establishment of tissue polarity 0.819398 5488 binding 0.819398 6461 protein complex assembly 0.819335 10173 voltage-gated calcium channel activity 0.819319 46920 alpha(1,3)-fucosyltransferase activity 0.819246 7099 centriole replication 0.819029 8093 cytoskeletal adaptor activity 0.819015 22804 active transmembrane transporter activity 0.818997 43062 extracellular structure organization 0.818893 30274 LIM domain binding 0.818884 45263 proton-transporting ATP synthase complex, coupling factor F(o) 0.818795 1671 ATPase activator activity 0.818749 8131 amine oxidase activity 0.818672 15299 solute:hydrogen antiporter activity 0.818565 31143 pseudopodium 0.818522 5041 low-density lipoprotein receptor activity 0.818498 8584 male gonad development 0.818406 19902 phosphatase binding 0.818247 4673 protein histidine kinase activity 0.818220 8896 protein histidine kinase activity 0.818220 155 two-component sensor activity 0.818220 4957 prostaglandin E receptor activity 0.818218 30492 hemoglobin binding 0.818145 188 inactivation of MAPK activity 0.818142 44448 cell cortex part 0.818071 5164 tumor necrosis factor receptor binding 0.818062 16196 endocytosis 0.817776 16193 endocytosis 0.817776 8519 ammonium transmembrane transporter activity 0.817725 5579 membrane attack complex 0.817632 5230 extracellular ligand-gated ion channel activity 0.817555 31419 cobalamin binding 0.817427 31252 cell leading edge 0.817377 5602 complement component C1 complex 0.817245 50878 regulation of body fluid levels 0.817216 3987 acetate-CoA ligase activity 0.817179 1726 ruffle 0.817148 796 condensin complex 0.817146 42802 identical protein binding 0.817122 16309 1-phosphatidylinositol-5-phosphate 4-kinase activity 0.817115 51378 serotonin binding 0.817059 4396 hexokinase activity 0.817001 4526 ribonuclease P activity 0.816966 16043 cellular component organization 0.816897 15027 coreceptor, soluble ligand activity 0.816786 6901 vesicle coating 0.816764 3986 acetyl-CoA hydrolase activity 0.816713 7016 cytoskeletal anchoring at plasma membrane 0.816589 4806 triglyceride lipase activity 0.816586 5521 lamin binding 0.816576 5589 collagen type VI 0.816520 8109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity 0.816407 30971 receptor tyrosine kinase binding 0.816315 6465 signal peptide processing 0.816300 16862 intramolecular oxidoreductase activity, interconverting keto- and enol-groups 0.816251 70646 protein modification by small protein removal 0.816221 5093 Rab GDP-dissociation inhibitor activity 0.816110 5031 tumor necrosis factor receptor activity 0.816014 7420 brain development 0.815930 4743 pyruvate kinase activity 0.815772 8143 poly(A) RNA binding 0.815761 32940 secretion by cell 0.815674 43202 lysosomal lumen 0.815571 4995 tachykinin receptor activity 0.815570 5954 calcium- and calmodulin-dependent protein kinase complex 0.815524 8375 acetylglucosaminyltransferase activity 0.815388 16944 RNA polymerase II transcription elongation factor activity 0.815348 5112 Notch binding 0.815237 40008 regulation of growth 0.815237 9897 external side of plasma membrane 0.815184 15056 corticotrophin-releasing factor receptor activity 0.815120 7167 enzyme linked receptor protein signaling pathway 0.815116 5774 vacuolar membrane 0.814996 9966 regulation of signal transduction 0.814895 45179 apical cortex 0.814781 6629 lipid metabolic process 0.814700 8140 cAMP response element binding protein binding 0.814555 44449 contractile fiber part 0.814529 22839 ion gated channel activity 0.814463 4896 cytokine receptor activity 0.814391 6839 mitochondrial transport 0.814331 6821 chloride transport 0.814185 8028 monocarboxylic acid transmembrane transporter activity 0.814075 42043 neurexin binding 0.813852 4157 dihydropyrimidinase activity 0.813822 4873 asialoglycoprotein receptor activity 0.813815 16653 oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor 0.813798 7266 Rho protein signal transduction 0.813694 17134 fibroblast growth factor binding 0.813688 3682 chromatin binding 0.813569 19003 GDP binding 0.813560 3835 beta-galactoside alpha-2,6-sialyltransferase activity 0.813526 16835 carbon-oxygen lyase activity 0.813502 5066 transmembrane receptor protein tyrosine kinase signaling protein activity 0.813493 22607 cellular component assembly 0.813443 15377 cation:chloride symporter activity 0.813400 51403 stress-activated MAPK cascade 0.813285 30374 ligand-dependent nuclear receptor transcription coactivator activity 0.813135 6432 phenylalanyl-tRNA aminoacylation 0.813134 6836 neurotransmitter transport 0.813117 15384 anion exchanger activity 0.813057 5452 inorganic anion exchanger activity 0.813057 4497 monooxygenase activity 0.813055 16289 CoA hydrolase activity 0.812920 339 RNA cap binding 0.812856 4998 transferrin receptor activity 0.812850 8157 protein phosphatase 1 binding 0.812849 3709 RNA polymerase III transcription factor activity 0.812778 6855 multidrug transport 0.812778 43204 perikaryon 0.812771 6406 mRNA export from nucleus 0.812767 15645 fatty-acid ligase activity 0.812727 1502 cartilage condensation 0.812593 8429 phosphatidylethanolamine binding 0.812575 8408 3'-5' exonuclease activity 0.812533 3697 single-stranded DNA binding 0.812527 15276 ligand-gated ion channel activity 0.812518 22834 ligand-gated channel activity 0.812518 30425 dendrite 0.812460 4430 1-phosphatidylinositol 4-kinase activity 0.812361 15293 symporter activity 0.812272 30521 androgen receptor signaling pathway 0.812204 31418 L-ascorbic acid binding 0.812203 10608 posttranscriptional regulation of gene expression 0.812143 15101 organic cation transmembrane transporter activity 0.812141 15290 secondary active transmembrane transporter activity 0.812070 4307 ethanolaminephosphotransferase activity 0.812060 8503 benzodiazepine receptor activity 0.811928 16853 isomerase activity 0.811912 15291 secondary active transmembrane transporter activity 0.811905 15297 antiporter activity 0.811873 31849 olfactory receptor binding 0.811803 15270 dihydropyridine-sensitive calcium channel activity 0.811684 51869 response to stimulus 0.811648 43631 RNA polyadenylation 0.811526 5883 neurofilament 0.811526 9620 response to fungus 0.811519 276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) 0.811494 43197 dendritic spine 0.811366 6613 cotranslational protein targeting to membrane 0.811344 30901 midbrain development 0.811199 2474 antigen processing and presentation of peptide antigen via MHC class I 0.811147 44236 multicellular organismal metabolic process 0.811119 31163 metallo-sulfur cluster assembly 0.811082 16226 iron-sulfur cluster assembly 0.811082 79 regulation of cyclin-dependent protein kinase activity 0.811057 16499 orexin receptor activity 0.810870 6310 DNA recombination 0.810645 5792 microsome 0.810588 30118 clathrin coat 0.810586 16579 protein deubiquitination 0.810455 44238 primary metabolic process 0.810376 33842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity 0.810267 9611 response to wounding 0.810261 6378 mRNA polyadenylation 0.810261 51131 chaperone-mediated protein complex assembly 0.810207 43292 contractile fiber 0.810206 7506 gonadal mesoderm development 0.810064 16190 clathrin coat 0.810061 30306 ADP-ribosylation factor binding 0.809977 5100 Rho GTPase activator activity 0.809965 55114 oxidation reduction 0.809948 4060 arylamine N-acetyltransferase activity 0.809887 30551 cyclic nucleotide binding 0.809784 6399 tRNA metabolic process 0.809760 42598 vesicular fraction 0.809694 3688 DNA replication origin binding 0.809481 4370 glycerol kinase activity 0.809469 15125 bile acid transmembrane transporter activity 0.809459 33554 cellular response to stress 0.809411 8526 phosphatidylinositol transporter activity 0.809292 15018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity 0.809243 5545 phosphatidylinositol binding 0.809008 16798 hydrolase activity, acting on glycosyl bonds 0.808958 5902 microvillus 0.808739 16514 SWI/SNF complex 0.808550 70603 SWI/SNF-type complex 0.808550 5581 collagen 0.808515 43933 macromolecular complex subunit organization 0.808439 34600 macromolecular complex subunit organization 0.808439 5126 cytokine receptor binding 0.808394 46906 tetrapyrrole binding 0.808373 6807 nitrogen compound metabolic process 0.808336 70775 H3 histone acetyltransferase complex 0.808282 70776 MOZ/MORF histone acetyltransferase complex 0.808282 5850 eukaryotic translation initiation factor 2 complex 0.808261 50780 dopamine receptor binding 0.808229 30333 antigen processing and presentation 0.808220 43189 H4/H2A histone acetyltransferase complex 0.808186 9890 negative regulation of biosynthetic process 0.808116 7222 Wnt receptor signaling pathway 0.807895 16559 peroxisome fission 0.807833 16814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 0.807827 70688 MLL5-L complex 0.807802 31386 protein tag 0.807755 5952 cAMP-dependent protein kinase complex 0.807705 62 acyl-CoA binding 0.807694 5385 zinc ion transmembrane transporter activity 0.807672 48515 spermatid differentiation 0.807659 4649 poly(ADP-ribose) glycohydrolase activity 0.807611 1525 angiogenesis 0.807548 6368 RNA elongation from RNA polymerase II promoter 0.807527 5497 androgen binding 0.807507 20037 heme binding 0.807495 63 nucleocytoplasmic transport 0.807324 15463 protein transporter activity 0.807315 6401 RNA catabolic process 0.807261 70925 organelle assembly 0.807259 1890 placenta development 0.807252 30983 mismatched DNA binding 0.807251 5178 integrin binding 0.807191 44440 endosomal part 0.806910 16491 oxidoreductase activity 0.806874 5087 Ran guanyl-nucleotide exchange factor activity 0.806858 30855 epithelial cell differentiation 0.806761 2245 response to wounding 0.806672 32794 GTPase activating protein binding 0.806621 31327 negative regulation of cellular biosynthetic process 0.806615 16755 transferase activity, transferring amino-acyl groups 0.806585 6903 vesicle targeting 0.806482 42579 microbody 0.806171 46836 glycolipid transport 0.806132 51085 chaperone mediated protein folding requiring cofactor 0.806100 45109 intermediate filament organization 0.805968 118 histone deacetylase complex 0.805917 3829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity 0.805895 48027 mRNA 5'-UTR binding 0.805890 3951 NAD+ kinase activity 0.805800 16763 transferase activity, transferring pentosyl groups 0.805706 5777 peroxisome 0.805624 30125 clathrin vesicle coat 0.805609 6471 protein amino acid ADP-ribosylation 0.805494 5537 mannose binding 0.805460 5740 mitochondrial envelope 0.805351 45116 protein neddylation 0.805259 17070 U6 snRNA binding 0.805213 8073 ornithine decarboxylase inhibitor activity 0.805201 6611 protein export from nucleus 0.805086 5662 DNA replication factor A complex 0.805054 19005 SCF ubiquitin ligase complex 0.805044 30688 preribosome, small subunit precursor 0.804979 30935 sheet-forming collagen 0.804901 3810 protein-glutamine gamma-glutamyltransferase activity 0.804846 30029 actin filament-based process 0.804746 4000 adenosine deaminase activity 0.804735 31519 PcG protein complex 0.804475 5391 sodium:potassium-exchanging ATPase activity 0.804459 5765 lysosomal membrane 0.804446 6605 protein targeting 0.804431 3858 3-hydroxybutyrate dehydrogenase activity 0.804110 19166 trans-2-enoyl-CoA reductase (NADPH) activity 0.804085 15036 disulfide oxidoreductase activity 0.804057 7411 axon guidance 0.804042 4128 cytochrome-b5 reductase activity 0.803997 35036 sperm-egg recognition 0.803992 7339 binding of sperm to zona pellucida 0.803992 5614 interstitial matrix 0.803980 8528 peptide receptor activity, G-protein coupled 0.803775 1653 peptide receptor activity 0.803775 4415 hyalurononglucosaminidase activity 0.803750 35145 exon-exon junction complex 0.803706 8301 DNA bending activity 0.803671 30178 negative regulation of Wnt receptor signaling pathway 0.803614 7205 activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway 0.803576 30742 GTP-dependent protein binding 0.803370 46658 anchored to plasma membrane 0.803222 5682 U5 snRNP 0.803221 228 nuclear chromosome 0.803156 7281 germ cell development 0.803110 8643 carbohydrate transport 0.803110 6953 acute-phase response 0.803107 48154 S100 beta binding 0.803101 1965 G-protein alpha-subunit binding 0.802806 6610 ribosomal protein import into nucleus 0.802659 4749 ribose phosphate diphosphokinase activity 0.802656 9583 detection of light stimulus 0.802548 6493 protein amino acid O-linked glycosylation 0.802534 5506 iron ion binding 0.802516 6913 nucleocytoplasmic transport 0.802486 7032 endosome organization 0.802431 6487 protein amino acid N-linked glycosylation 0.802402 4521 endoribonuclease activity 0.802334 70838 divalent metal ion transport 0.802239 51169 nuclear transport 0.802164 18149 peptide cross-linking 0.802150 8170 N-methyltransferase activity 0.802061 8486 diphosphoinositol-polyphosphate diphosphatase activity 0.802038 16864 intramolecular oxidoreductase activity, transposing S-S bonds 0.801963 3756 protein disulfide isomerase activity 0.801963 4090 carbonyl reductase (NADPH) activity 0.801917 4169 dolichyl-phosphate-mannose-protein mannosyltransferase activity 0.801736 51649 establishment of localization in cell 0.801533 5011 macrophage colony stimulating factor receptor activity 0.801526 8015 blood circulation 0.801501 31974 membrane-enclosed lumen 0.801478 5811 lipid particle 0.801447 15035 protein disulfide oxidoreductase activity 0.801443 43394 proteoglycan binding 0.801411 31092 platelet alpha granule membrane 0.801280 10558 negative regulation of macromolecule biosynthetic process 0.801272 16308 1-phosphatidylinositol-4-phosphate 5-kinase activity 0.801237 51766 inositol trisphosphate kinase activity 0.801209 8146 sulfotransferase activity 0.801081 34704 calcium channel complex 0.801043 7169 transmembrane receptor protein tyrosine kinase signaling pathway 0.800833 44441 cilium part 0.800790 31262 Ndc80 complex 0.800686 8360 regulation of cell shape 0.800645 10008 endosome membrane 0.800645 42551 neuron maturation 0.800520 70085 glycosylation 0.800469 43413 macromolecule glycosylation 0.800469 6486 protein amino acid glycosylation 0.800469 16701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 0.800435 6944 membrane fusion 0.800268 7286 spermatid development 0.800171 6869 lipid transport 0.800147 18206 peptidyl-methionine modification 0.800142 9755 hormone-mediated signaling pathway 0.800079 15379 potassium:chloride symporter activity 0.800046 4434 inositol or phosphatidylinositol phosphodiesterase activity 0.799981 4435 phosphoinositide phospholipase C activity 0.799981 42298 phospholipase C activity 0.799981 16836 hydro-lyase activity 0.799966 8250 oligosaccharyltransferase complex 0.799937 16766 transferase activity, transferring alkyl or aryl (other than methyl) groups 0.799709 30036 actin cytoskeleton organization 0.799707 6120 mitochondrial electron transport, NADH to ubiquinone 0.799574 16286 small conductance calcium-activated potassium channel activity 0.799488 65003 macromolecular complex assembly 0.799376 45308 protein binding 0.799319 17038 protein import 0.799252 9888 tissue development 0.799187 7010 cytoskeleton organization 0.799185 6816 calcium ion transport 0.798988 45103 intermediate filament-based process 0.798985 9986 cell surface 0.798904 6354 RNA elongation 0.798626 16655 oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor 0.798589 16878 acid-thiol ligase activity 0.798366 12511 monolayer-surrounded lipid storage body 0.798340 9303 rRNA transcription 0.798284 42273 ribosomal large subunit biogenesis 0.798244 47498 calcium-dependent phospholipase A2 activity 0.798235 4540 ribonuclease activity 0.798216 16702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 0.798150 51213 dioxygenase activity 0.798150 48869 cellular developmental process 0.798007 7269 neurotransmitter secretion 0.797863 35097 histone methyltransferase complex 0.797794 34708 methyltransferase complex 0.797794 30552 cAMP binding 0.797718 4879 ligand-dependent nuclear receptor activity 0.797670 15349 thyroid hormone transmembrane transporter activity 0.797663 31675 NADH dehydrogenase complex 0.797624 31678 NADH dehydrogenase complex 0.797624 31677 NADH dehydrogenase complex 0.797624 45271 respiratory chain complex I 0.797624 45279 respiratory chain complex I 0.797624 45280 NADH dehydrogenase complex 0.797624 30025 NADH dehydrogenase complex 0.797624 5747 mitochondrial respiratory chain complex I 0.797624 30964 NADH dehydrogenase complex 0.797624 30966 NADH dehydrogenase complex 0.797624 30684 preribosome 0.797580 1867 complement activation, lectin pathway 0.797559 70469 respiratory chain 0.797529 4741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity 0.797470 30175 filopodium 0.797436 51225 spindle assembly 0.797333 4768 stearoyl-CoA 9-desaturase activity 0.797315 5744 mitochondrial inner membrane presequence translocase complex 0.797311 33116 ER-Golgi intermediate compartment membrane 0.797252 19825 oxygen binding 0.797241 3912 DNA nucleotidylexotransferase activity 0.797204 42769 DNA damage response, detection of DNA damage 0.797131 16877 ligase activity, forming carbon-sulfur bonds 0.797092 5673 transcription factor TFIIE complex 0.797083 86 G2/M transition of mitotic cell cycle 0.797000 5005 transmembrane-ephrin receptor activity 0.796986 51018 protein kinase A binding 0.796932 8641 small protein activating enzyme activity 0.796848 82 G1/S transition of mitotic cell cycle 0.796639 17110 nucleoside-diphosphatase activity 0.796440 15459 potassium channel regulator activity 0.796423 5801 cis-Golgi network 0.796422 42995 cell projection 0.796395 5021 vascular endothelial growth factor receptor activity 0.796179 30396 extrinsic to membrane 0.796090 1503 ossification 0.796077 30141 secretory granule 0.796072 48200 Golgi transport vesicle coating 0.796014 48205 COPI coating of Golgi vesicle 0.796014 17069 snRNA binding 0.795942 51172 negative regulation of nitrogen compound metabolic process 0.795805 4720 protein-lysine 6-oxidase activity 0.795592 8271 secondary active sulfate transmembrane transporter activity 0.795570 1786 phosphatidylserine binding 0.795378 6957 complement activation, alternative pathway 0.795352 16197 endosome transport 0.795230 3729 mRNA binding 0.795048 5890 sodium:potassium-exchanging ATPase complex 0.795032 6805 xenobiotic metabolic process 0.795026 51253 negative regulation of RNA metabolic process 0.795015 4553 hydrolase activity, hydrolyzing O-glycosyl compounds 0.794997 15269 calcium-activated potassium channel activity 0.794960 4949 cannabinoid receptor activity 0.794958 5844 polysome 0.794927 43484 regulation of RNA splicing 0.794897 7602 phototransduction 0.794869 15016 [heparan sulfate]-glucosamine N-sulfotransferase activity 0.794854 19079 viral genome replication 0.794723 5787 signal peptidase complex 0.794707 3995 acyl-CoA dehydrogenase activity 0.794520 4597 peptide-aspartate beta-dioxygenase activity 0.794432 4017 adenylate kinase activity 0.794380 4687 myosin light chain kinase activity 0.794305 5669 transcription factor TFIID complex 0.794233 16600 flotillin complex 0.794154 10576 metalloenzyme regulator activity 0.794130 48551 metalloenzyme inhibitor activity 0.794130 8191 metalloendopeptidase inhibitor activity 0.794130 6996 organelle organization 0.794073 16407 acetyltransferase activity 0.793955 178 exosome (RNase complex) 0.793945 45934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 0.793871 50808 synapse organization 0.793829 42165 neurotransmitter binding 0.793817 43233 organelle lumen 0.793811 16792 phosphoric diester hydrolase activity 0.793808 8081 phosphoric diester hydrolase activity 0.793808 785 chromatin 0.793759 8307 structural constituent of muscle 0.793456 45892 negative regulation of transcription, DNA-dependent 0.793399 7185 transmembrane receptor protein tyrosine phosphatase signaling pathway 0.793244 16493 C-C chemokine receptor activity 0.793180 19957 C-C chemokine binding 0.793180 5626 insoluble fraction 0.793135 4968 gonadotropin-releasing hormone receptor activity 0.793027 6890 retrograde vesicle-mediated transport, Golgi to ER 0.792984 1501 skeletal system development 0.792957 4652 polynucleotide adenylyltransferase activity 0.792949 4700 protein serine/threonine kinase activity 0.792906 6950 response to stress 0.792789 48306 calcium-dependent protein binding 0.792783 5227 calcium activated cation channel activity 0.792459 3824 catalytic activity 0.792425 5624 membrane fraction 0.792398 15674 di-, tri-valent inorganic cation transport 0.792301 267 cell fraction 0.792293 22900 electron transport chain 0.792234 6958 complement activation, classical pathway 0.792199 8508 bile acid:sodium symporter activity 0.792018 6376 mRNA splice site selection 0.791906 48770 pigment granule 0.791878 42470 melanosome 0.791878 5549 odorant binding 0.791826 30594 neurotransmitter receptor activity 0.791736 6954 inflammatory response 0.791728 5664 nuclear origin of replication recognition complex 0.791691 30144 alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase activity 0.791687 15931 nucleobase, nucleoside, nucleotide and nucleic acid transport 0.791676 5789 endoplasmic reticulum membrane 0.791649 16789 carboxylesterase activity 0.791603 4759 carboxylesterase activity 0.791603 4302 carboxylesterase activity 0.791603 46966 thyroid hormone receptor binding 0.791519 4719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity 0.791343 3730 mRNA 3'-UTR binding 0.791300 8373 sialyltransferase activity 0.791232 45125 bioactive lipid receptor activity 0.791132 1619 lysosphingolipid and lysophosphatidic acid receptor activity 0.791132 16167 glial cell line-derived neurotrophic factor receptor activity 0.790975 8137 NADH dehydrogenase (ubiquinone) activity 0.790803 50136 NADH dehydrogenase (quinone) activity 0.790803 3954 NADH dehydrogenase activity 0.790803 19835 cytolysis 0.790609 44431 Golgi apparatus part 0.790406 8320 protein transmembrane transporter activity 0.790350 6383 transcription from RNA polymerase III promoter 0.790310 7181 transforming growth factor beta receptor complex assembly 0.790264 15923 mannosidase activity 0.790207 4826 phenylalanine-tRNA ligase activity 0.790157 19897 extrinsic to plasma membrane 0.790003 42989 sequestering of actin monomers 0.789713 6626 protein targeting to mitochondrion 0.789619 42274 ribosomal small subunit biogenesis 0.789618 48856 anatomical structure development 0.789465 22892 substrate-specific transporter activity 0.789273 16894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 0.789076 9621 response to fungus 0.789063 8509 anion transmembrane transporter activity 0.788918 46907 intracellular transport 0.788800 7059 chromosome segregation 0.788691 22829 wide pore channel activity 0.788553 4727 prenylated protein tyrosine phosphatase activity 0.788536 4620 phospholipase activity 0.788517 44432 endoplasmic reticulum part 0.788482 5680 anaphase-promoting complex 0.788023 6606 protein import into nucleus 0.787904 4994 somatostatin receptor activity 0.787877 7021 tubulin complex assembly 0.787850 5638 lamin filament 0.787769 15074 DNA integration 0.787654 4707 MAP kinase activity 0.787602 22891 substrate-specific transmembrane transporter activity 0.787591 19956 chemokine binding 0.787528 7599 hemostasis 0.787517 30156 benzodiazepine receptor binding 0.787449 8324 cation transmembrane transporter activity 0.787387 6935 chemotaxis 0.787366 42330 taxis 0.787366 15831 protein transport 0.787358 6417 regulation of translation 0.787137 157 extrinsic to plasma membrane 0.787080 42788 polysomal ribosome 0.787054 4703 G-protein coupled receptor kinase activity 0.786891 44424 intracellular part 0.786848 6895 Golgi to endosome transport 0.786615 4950 chemokine receptor activity 0.786557 1637 G-protein chemoattractant receptor activity 0.786557 31640 killing of cells of another organism 0.786553 30134 ER to Golgi transport vesicle 0.786530 3707 steroid hormone receptor activity 0.786494 7268 synaptic transmission 0.786455 2541 activation of plasma proteins involved in acute inflammatory response 0.786382 6402 mRNA catabolic process 0.786165 45087 innate immune response 0.785988 6359 regulation of transcription from RNA polymerase III promoter 0.785856 16529 sarcoplasmic reticulum 0.785575 16363 nuclear matrix 0.785473 122 negative regulation of transcription from RNA polymerase II promoter 0.785457 31901 early endosome membrane 0.785292 4946 bombesin receptor activity 0.785274 4709 MAP kinase kinase kinase activity 0.785226 1664 G-protein-coupled receptor binding 0.785187 16765 transferase activity, transferring alkyl or aryl (other than methyl) groups 0.785073 30880 RNA polymerase complex 0.785009 5478 transporter activity 0.784936 5158 insulin receptor binding 0.784925 50954 sensory perception of mechanical stimulus 0.784902 18298 protein-chromophore linkage 0.784882 50817 coagulation 0.784881 7596 blood coagulation 0.784881 15450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity 0.784850 22884 macromolecule transmembrane transporter activity 0.784850 6446 regulation of translational initiation 0.784848 16042 lipid catabolic process 0.784829 16044 membrane organization 0.784764 1539 ciliary or flagellar motility 0.784685 19882 antigen processing and presentation 0.784603 34984 cellular response to DNA damage stimulus 0.784521 42255 ribosome assembly 0.784477 50291 sphingosine N-acyltransferase activity 0.784361 5487 nucleocytoplasmic transporter activity 0.784345 34621 cellular macromolecular complex subunit organization 0.784340 50957 equilibrioception 0.784245 48496 maintenance of organ identity 0.784241 8378 galactosyltransferase activity 0.784162 4865 protein serine/threonine phosphatase inhibitor activity 0.784110 16581 NuRD complex 0.784108 30035 microspike assembly 0.784071 31090 organelle membrane 0.783757 30897 HOPS complex 0.783711 956 nuclear-transcribed mRNA catabolic process 0.783658 51170 nuclear import 0.783567 6974 response to DNA damage stimulus 0.783413 44419 interspecies interaction between organisms 0.783328 10629 negative regulation of gene expression 0.783297 70742 C2H2 zinc finger domain binding 0.783069 4145 diamine N-acetyltransferase activity 0.783031 16298 lipase activity 0.783003 16410 N-acyltransferase activity 0.782999 1558 regulation of cell growth 0.782990 16779 nucleotidyltransferase activity 0.782982 7398 ectoderm development 0.782975 19904 protein domain specific binding 0.782837 15646 transmembrane transporter activity 0.782805 5386 transmembrane transporter activity 0.782805 22857 transmembrane transporter activity 0.782805 17147 Wnt-protein binding 0.782747 7157 heterophilic cell adhesion 0.782570 30354 melanin-concentrating hormone activity 0.782379 8599 protein phosphatase type 1 regulator activity 0.782360 159 protein phosphatase type 2A complex 0.782260 42054 histone methyltransferase activity 0.782222 5776 autophagic vacuole 0.782190 44420 extracellular matrix part 0.782097 31214 biomineral formation 0.781883 5507 copper ion binding 0.781861 43234 protein complex 0.781816 6956 complement activation 0.781571 5625 soluble fraction 0.781570 5862 muscle thin filament tropomyosin 0.781513 7265 Ras protein signal transduction 0.781381 8308 voltage-gated anion channel activity 0.781358 17048 Rho GTPase binding 0.781329 9881 photoreceptor activity 0.781228 16932 transferase activity, transferring glycosyl groups 0.781210 5829 cytosol 0.781082 6259 DNA metabolic process 0.780991 44259 multicellular organismal macromolecule metabolic process 0.780921 44444 cytoplasmic part 0.780792 7214 gamma-aminobutyric acid signaling pathway 0.780776 19199 transmembrane receptor protein kinase activity 0.780761 19865 immunoglobulin binding 0.780713 31080 Nup107-160 complex 0.780599 808 origin recognition complex 0.780509 30018 Z disc 0.780507 32982 myosin filament 0.780423 5577 fibrinogen complex 0.780384 185 activation of MAPKKK activity 0.780382 7605 sensory perception of sound 0.780326 16568 chromatin modification 0.780306 5587 collagen type IV 0.780292 55085 transmembrane transport 0.780214 17089 glycolipid transporter activity 0.780198 5667 transcription factor complex 0.780073 15075 ion transmembrane transporter activity 0.780036 5665 DNA-directed RNA polymerase II, core complex 0.779516 4629 phospholipase C activity 0.779435 4112 cyclic-nucleotide phosphodiesterase activity 0.779400 19201 nucleotide kinase activity 0.779330 8276 protein methyltransferase activity 0.779149 6886 intracellular protein transport 0.779129 15280 amiloride-sensitive sodium channel activity 0.779067 5499 vitamin D binding 0.779025 4002 ATPase activity 0.778893 42623 ATPase activity, coupled 0.778873 5814 centriole 0.778802 14069 postsynaptic density 0.778763 7500 mesodermal cell fate determination 0.778675 16481 negative regulation of transcription 0.778464 5262 calcium channel activity 0.778425 16013 syntrophin complex 0.778419 55029 nuclear DNA-directed RNA polymerase complex 0.778361 428 DNA-directed RNA polymerase complex 0.778361 8201 heparin binding 0.778345 19717 synaptosome 0.778316 4683 calmodulin-dependent protein kinase activity 0.777963 8934 inositol-1(or 4)-monophosphatase activity 0.777933 3796 lysozyme activity 0.777894 19867 outer membrane 0.777810 7050 cell cycle arrest 0.777772 8440 inositol trisphosphate 3-kinase activity 0.777748 16500 protein-hormone receptor activity 0.777708 6959 humoral immune response 0.777436 42808 neuronal Cdc2-like kinase binding 0.777370 70876 SOSS complex 0.776985 2504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 0.776847 22844 voltage-gated anion channel activity 0.776708 5247 voltage-gated chloride channel activity 0.776708 6357 regulation of transcription from RNA polymerase II promoter 0.776704 30121 AP-1 adaptor complex 0.776682 34660 ncRNA metabolic process 0.776646 42801 polo kinase kinase activity 0.776565 22402 cell cycle process 0.776181 5871 kinesin complex 0.776022 22618 ribonucleoprotein complex assembly 0.776004 44243 multicellular organismal catabolic process 0.775932 8188 neuropeptide receptor activity 0.775819 6352 transcription initiation 0.775750 51340 regulation of ligase activity 0.775681 9649 entrainment of circadian clock 0.775600 777 condensed chromosome kinetochore 0.775520 5699 kinetochore 0.775520 776 kinetochore 0.775435 51706 multi-organism process 0.775410 51704 multi-organism process 0.775410 4623 phospholipase A2 activity 0.775001 5245 voltage-gated calcium channel activity 0.774969 70290 NAPE-specific phospholipase D activity 0.774934 7001 chromosome organization 0.774828 51277 chromosome organization 0.774828 15924 mannosyl-oligosaccharide mannosidase activity 0.774681 5938 cell cortex 0.774486 16758 transferase activity, transferring hexosyl groups 0.774304 42923 neuropeptide binding 0.774127 44429 mitochondrial part 0.774077 50657 nucleic acid transport 0.774072 50658 RNA transport 0.774072 51236 establishment of RNA localization 0.774072 47372 acylglycerol lipase activity 0.773910 31648 protein destabilization 0.773893 30135 coated vesicle 0.773771 4114 3',5'-cyclic-nucleotide phosphodiesterase activity 0.773532 6139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 0.773427 51276 chromosome organization 0.773393 4985 opioid receptor activity 0.773228 31968 organelle outer membrane 0.773190 6260 DNA replication 0.773145 33883 pyridoxal phosphatase activity 0.773131 5654 nucleoplasm 0.773125 30120 vesicle coat 0.773095 3836 beta-galactoside alpha-2,3-sialyltransferase activity 0.772959 31402 sodium ion binding 0.772862 6367 transcription initiation from RNA polymerase II promoter 0.772691 4117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity 0.772508 16503 pheromone receptor activity 0.772433 19236 response to pheromone 0.772433 51351 positive regulation of ligase activity 0.772422 184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 0.772397 2376 immune system process 0.772386 8033 tRNA processing 0.772262 3840 gamma-glutamyltransferase activity 0.772241 34622 cellular macromolecular complex assembly 0.772199 8514 organic anion transmembrane transporter activity 0.772123 8080 N-acetyltransferase activity 0.772057 8283 cell proliferation 0.771958 15460 transport 0.771892 1871 pattern binding 0.771840 30247 polysaccharide binding 0.771840 70206 protein trimerization 0.771786 32549 ribonucleoside binding 0.771768 15457 transport 0.771754 30016 myofibril 0.771744 8194 UDP-glycosyltransferase activity 0.771719 10498 proteasomal protein catabolic process 0.771710 43161 proteasomal ubiquitin-dependent protein catabolic process 0.771710 32991 macromolecular complex 0.771687 5102 receptor binding 0.771660 44422 organelle part 0.771596 44456 synapse part 0.771547 1824 blastocyst development 0.771507 6814 sodium ion transport 0.771497 9617 response to bacterium 0.771172 17053 transcriptional repressor complex 0.771168 45211 postsynaptic membrane 0.771074 34061 DNA polymerase activity 0.770950 5539 glycosaminoglycan binding 0.770911 16887 ATPase activity 0.770898 31965 nuclear membrane 0.770864 4519 endonuclease activity 0.770838 5891 voltage-gated calcium channel complex 0.770818 51444 negative regulation of ubiquitin-protein ligase activity 0.770776 51352 negative regulation of ligase activity 0.770776 32502 developmental process 0.770755 5909 coated vesicle 0.770708 45182 translation regulator activity 0.770639 44446 intracellular organelle part 0.770587 6891 intra-Golgi vesicle-mediated transport 0.770461 7229 integrin-mediated signaling pathway 0.770445 4993 serotonin receptor activity 0.770402 5184 neuropeptide hormone activity 0.770319 42787 protein ubiquitination during ubiquitin-dependent protein catabolic process 0.770183 51438 regulation of ubiquitin-protein ligase activity 0.770096 7126 meiosis 0.769751 33018 sarcoplasmic reticulum lumen 0.769631 16022 endoplasmic reticulum lumen 0.769631 30154 cell differentiation 0.769505 6819 cation transport 0.769349 3998 acylphosphatase activity 0.769316 7089 traversing start control point of mitotic cell cycle 0.769263 5251 delayed rectifier potassium channel activity 0.769092 7243 protein kinase cascade 0.769038 16563 transcription activator activity 0.768820 5905 coated pit 0.768790 6281 DNA repair 0.768719 44427 chromosomal part 0.768706 60040 retinal bipolar neuron differentiation 0.768694 15467 G-protein activated inward rectifier potassium channel activity 0.768654 8454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity 0.768500 6812 cation transport 0.768477 2217 defense response 0.768462 42829 defense response 0.768462 8502 melatonin receptor activity 0.768412 165 MAPKKK cascade 0.768338 1515 opioid peptide activity 0.768259 5769 early endosome 0.768178 43168 anion binding 0.768008 70013 intracellular organelle lumen 0.767974 32190 acrosin binding 0.767966 6811 ion transport 0.767908 46847 filopodium assembly 0.767896 16746 transferase activity, transferring acyl groups 0.767750 70647 protein modification by small protein conjugation or removal 0.767652 30136 clathrin-coated vesicle 0.767573 32420 stereocilium 0.767502 15669 gas transport 0.767465 8277 regulation of G-protein coupled receptor protein signaling pathway 0.767428 139 Golgi membrane 0.767386 30117 membrane coat 0.767325 5838 proteasome regulatory particle 0.766786 30126 COPI vesicle coat 0.766743 43412 macromolecule modification 0.766661 7292 female gamete generation 0.766657 4965 GABA-B receptor activity 0.766058 51443 positive regulation of ubiquitin-protein ligase activity 0.766037 70008 serine-type exopeptidase activity 0.765979 4185 serine-type carboxypeptidase activity 0.765979 51028 mRNA transport 0.765769 43205 fibril 0.765741 1520 outer dense fiber 0.765554 287 magnesium ion binding 0.765446 30027 lamellipodium 0.765348 44451 nucleoplasm part 0.765174 6356 regulation of transcription from RNA polymerase I promoter 0.765062 4010 RNA-dependent ATPase activity 0.764978 4004 ATP-dependent RNA helicase activity 0.764978 32963 collagen metabolic process 0.764761 8415 acyltransferase activity 0.764333 31145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process 0.764318 16747 transferase activity, transferring acyl groups other than amino-acyl groups 0.764260 34706 sodium channel complex 0.764210 8134 transcription factor binding 0.763905 16010 dystrophin-associated glycoprotein complex 0.763743 4143 diacylglycerol kinase activity 0.763659 5272 sodium channel activity 0.763642 16740 transferase activity 0.763580 8484 sulfuric ester hydrolase activity 0.763572 5686 U2 snRNP 0.763478 70652 HAUS complex 0.763465 51436 negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle 0.763394 6887 exocytosis 0.763389 9680 response to bacterium 0.763389 9618 response to bacterium 0.763389 31988 membrane-bounded vesicle 0.763050 16502 nucleotide receptor activity 0.762959 1614 purinergic nucleotide receptor activity 0.762959 5742 mitochondrial outer membrane translocase complex 0.762926 7017 microtubule-based process 0.762866 5215 transporter activity 0.762845 8218 bioluminescence 0.762705 43122 regulation of I-kappaB kinase/NF-kappaB cascade 0.762642 4849 uridine kinase activity 0.762508 31975 envelope 0.762491 31967 organelle envelope 0.762491 5741 mitochondrial outer membrane 0.762394 16023 cytoplasmic membrane-bounded vesicle 0.762360 33150 cytoskeletal calyx 0.762270 43248 proteasome assembly 0.762190 15347 sodium-independent organic anion transmembrane transporter activity 0.761917 45 autophagic vacuole formation 0.761750 50832 defense response to fungus 0.761623 51707 response to other organism 0.761411 42828 response to other organism 0.761410 9613 response to other organism 0.761410 51301 cell division 0.761295 9607 response to biotic stimulus 0.761274 31267 small GTPase binding 0.761217 7267 cell-cell signaling 0.761176 51439 regulation of ubiquitin-protein ligase activity during mitotic cell cycle 0.761077 15630 microtubule cytoskeleton 0.760906 51437 positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle 0.760825 8252 nucleotidase activity 0.760792 15279 store-operated calcium channel activity 0.760763 6892 post-Golgi vesicle-mediated transport 0.760687 7498 mesoderm development 0.760684 5515 protein binding 0.760595 5243 gap junction channel activity 0.760532 19861 flagellum 0.760347 7254 JNK cascade 0.760116 16757 transferase activity, transferring glycosyl groups 0.760099 42813 Wnt receptor activity 0.759872 33829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity 0.759727 50896 response to stimulus 0.759712 3710 transcription activator activity 0.759488 3713 transcription coactivator activity 0.759488 6464 protein modification process 0.759483 16676 oxidoreductase activity, acting on heme group of donors, oxygen as acceptor 0.759475 16675 oxidoreductase activity, acting on heme group of donors 0.759475 4129 cytochrome-c oxidase activity 0.759475 15002 heme-copper terminal oxidase activity 0.759475 2088 lens development in camera-type eye 0.759469 44260 cellular macromolecule metabolic process 0.759054 34960 cellular macromolecule metabolic process 0.759054 16712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 0.759052 44447 axoneme part 0.758876 44248 cellular catabolic process 0.758594 8430 selenium binding 0.758501 8186 RNA-dependent ATPase activity 0.758296 43283 macromolecule metabolic process 0.758253 43170 macromolecule metabolic process 0.758253 8603 cAMP-dependent protein kinase regulator activity 0.757747 10324 membrane invagination 0.757683 5248 voltage-gated sodium channel activity 0.757484 43123 positive regulation of I-kappaB kinase/NF-kappaB cascade 0.757117 7416 synapse assembly 0.756924 6899 vesicle-mediated transport 0.756605 6826 iron ion transport 0.756603 32446 protein modification by small protein conjugation 0.756585 51234 establishment of localization 0.756547 46930 pore complex 0.756544 22836 gated channel activity 0.756472 31098 stress-activated protein kinase signaling pathway 0.756218 15672 monovalent inorganic cation transport 0.756183 4518 nuclease activity 0.756037 42742 defense response to bacterium 0.756032 34470 ncRNA processing 0.755734 1518 voltage-gated sodium channel complex 0.755733 46873 metal ion transmembrane transporter activity 0.755705 9615 response to virus 0.755679 8376 acetylgalactosaminyltransferase activity 0.755301 50811 GABA receptor binding 0.755211 51789 response to protein stimulus 0.755202 65007 biological regulation 0.754952 4697 protein kinase C activity 0.754698 6810 transport 0.754631 5819 spindle 0.754619 6270 DNA replication initiation 0.754588 5516 calmodulin binding 0.754336 6897 endocytosis 0.754328 22414 reproductive process 0.754206 31982 vesicle 0.754115 30001 metal ion transport 0.754108 22403 cell cycle phase 0.753724 17016 Ras GTPase binding 0.753071 6952 defense response 0.752970 31420 alkali metal ion binding 0.752682 70330 aromatase activity 0.752675 50381 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 0.752675 8402 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 0.752675 16567 protein ubiquitination 0.752650 1522 pseudouridine synthesis 0.752461 47555 3',5'-cyclic-GMP phosphodiesterase activity 0.752369 31410 cytoplasmic vesicle 0.752292 4999 vasoactive intestinal polypeptide receptor activity 0.752282 16917 GABA receptor activity 0.752256 43395 heparan sulfate proteoglycan binding 0.752106 9566 fertilization 0.752041 31461 cullin-RING ubiquitin ligase complex 0.751905 6909 phagocytosis 0.751848 16892 endoribonuclease activity, producing 3'-phosphomonoesters 0.751812 5095 GTPase inhibitor activity 0.751324 3725 double-stranded RNA binding 0.751179 4926 non-G-protein coupled 7TM receptor activity 0.751147 3711 transcription elongation regulator activity 0.750917 30145 manganese ion binding 0.750846 8083 growth factor activity 0.750829 4527 exonuclease activity 0.750645 5635 nuclear envelope 0.750594 30023 extracellular matrix constituent conferring elasticity 0.750551 6333 chromatin assembly or disassembly 0.750396 59 protein import into nucleus, docking 0.750365 444 MIS12/MIND type complex 0.750350 8601 protein phosphatase type 2A regulator activity 0.750279 6325 chromatin organization 0.750189 46875 ephrin receptor binding 0.750071 5833 hemoglobin complex 0.750036 31589 cell-substrate adhesion 0.750021 5666 DNA-directed RNA polymerase III complex 0.749898 6607 NLS-bearing substrate import into nucleus 0.749875 3823 antigen binding 0.749814 5678 chromatin assembly complex 0.749783 7242 intracellular signaling cascade 0.749550 15281 cation channel activity 0.749488 15338 cation channel activity 0.749488 5200 structural constituent of cytoskeleton 0.749269 4890 GABA-A receptor activity 0.749250 3956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity 0.749201 3887 DNA-directed DNA polymerase activity 0.748991 44459 plasma membrane part 0.748972 4571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity 0.748823 7158 neuron adhesion 0.748622 4091 carboxylesterase activity 0.748615 4622 lysophospholipase activity 0.748547 5261 cation channel activity 0.748495 4045 aminoacyl-tRNA hydrolase activity 0.748443 17119 Golgi transport complex 0.748300 43687 post-translational protein modification 0.748083 30131 clathrin adaptor complex 0.747771 18024 histone-lysine N-methyltransferase activity 0.747627 16278 lysine N-methyltransferase activity 0.747627 16279 protein-lysine N-methyltransferase activity 0.747627 5615 extracellular space 0.747573 8543 fibroblast growth factor receptor signaling pathway 0.747564 45454 cell redox homeostasis 0.747410 3704 specific RNA polymerase II transcription factor activity 0.747207 5253 anion channel activity 0.746602 30119 AP-type membrane coat adaptor complex 0.746221 15267 channel activity 0.746203 22803 passive transmembrane transporter activity 0.746203 15268 channel activity 0.746115 15249 channel activity 0.746115 4983 neuropeptide Y receptor activity 0.745995 8536 Ran GTPase binding 0.745603 32395 MHC class II receptor activity 0.745600 15671 oxygen transport 0.745597 5344 oxygen transporter activity 0.745597 30904 retromer complex 0.745464 4982 N-formyl peptide receptor activity 0.745444 33549 MAP kinase phosphatase activity 0.745407 17017 MAP kinase tyrosine/serine/threonine phosphatase activity 0.745407 22838 substrate-specific channel activity 0.745277 50501 hyaluronan synthase activity 0.745271 42613 MHC class II protein complex 0.745102 8287 protein serine/threonine phosphatase complex 0.744900 3993 acid phosphatase activity 0.744805 7219 Notch signaling pathway 0.744792 34702 ion channel complex 0.744133 7417 central nervous system development 0.743989 9982 pseudouridine synthase activity 0.743852 5858 axonemal dynein complex 0.743755 16564 transcription repressor activity 0.743750 51020 GTPase binding 0.743727 48477 oogenesis 0.743566 151 ubiquitin ligase complex 0.743543 35085 cilium axoneme 0.743437 31966 mitochondrial membrane 0.743229 8565 protein transporter activity 0.743201 5007 fibroblast growth factor receptor activity 0.743028 5254 chloride channel activity 0.743007 42147 retrograde transport, endosome to Golgi 0.742990 1882 nucleoside binding 0.742519 7030 Golgi organization 0.742439 32040 small-subunit processome 0.742127 16254 preassembly of GPI anchor in ER membrane 0.741957 387 spliceosomal snRNP assembly 0.741810 19783 small conjugating protein-specific protease activity 0.741746 16772 transferase activity, transferring phosphorus-containing groups 0.741620 5216 ion channel activity 0.741571 47961 glycine N-acyltransferase activity 0.741521 5885 Arp2/3 protein complex 0.741487 4714 transmembrane receptor protein tyrosine kinase activity 0.741377 5795 Golgi stack 0.741305 3712 transcription cofactor activity 0.741243 17176 phosphatidylinositol N-acetylglucosaminyltransferase activity 0.741222 1883 purine nucleoside binding 0.741192 44085 cellular component biogenesis 0.741065 5643 nuclear pore 0.741061 8092 cytoskeletal protein binding 0.740977 8544 epidermis development 0.740928 7586 digestion 0.740873 5242 inward rectifier potassium channel activity 0.740853 19888 protein phosphatase regulator activity 0.740785 30055 cell-substrate junction 0.740681 31404 chloride ion binding 0.740603 44445 cytosolic part 0.740563 4176 ATP-dependent peptidase activity 0.740454 3724 RNA helicase activity 0.740359 30127 COPII vesicle coat 0.740273 4062 aryl sulfotransferase activity 0.740246 45202 synapse 0.740200 5912 adherens junction 0.740195 30554 adenyl nucleotide binding 0.739937 5929 cilium 0.739563 16527 brain-specific angiogenesis inhibitor activity 0.739428 5788 endoplasmic reticulum lumen 0.739288 5773 vacuole 0.739079 2102 podosome 0.738856 16251 general RNA polymerase II transcription factor activity 0.738667 48193 Golgi vesicle transport 0.738414 5930 axoneme 0.738322 50789 regulation of biological process 0.738302 50791 regulation of biological process 0.738302 5924 cell-substrate adherens junction 0.737772 34062 RNA polymerase activity 0.737677 3899 DNA-directed RNA polymerase activity 0.737677 5921 gap junction 0.737506 5839 proteasome core complex 0.737088 19208 phosphatase regulator activity 0.736977 41 transition metal ion transport 0.736934 30955 potassium ion binding 0.736294 60090 molecular adaptor activity 0.736244 19866 organelle inner membrane 0.735695 8889 glycerophosphodiester phosphodiesterase activity 0.735611 5764 lysosome 0.735491 323 lytic vacuole 0.735491 22613 ribonucleoprotein complex biogenesis 0.734726 5694 chromosome 0.734546 8253 5'-nucleotidase activity 0.734386 9059 macromolecule biosynthetic process 0.734169 4843 ubiquitin-specific protease activity 0.734061 16073 snRNA metabolic process 0.733839 16180 snRNA processing 0.733839 7548 sex differentiation 0.733807 31226 intrinsic to plasma membrane 0.733674 8021 synaptic vesicle 0.733637 43284 macromolecule biosynthetic process 0.733569 5201 extracellular matrix structural constituent 0.733407 6986 response to unfolded protein 0.733236 34703 cation channel complex 0.733081 5125 cytokine activity 0.733075 5925 focal adhesion 0.732725 42578 phosphoric ester hydrolase activity 0.732615 16879 ligase activity, forming carbon-nitrogen bonds 0.732483 43226 organelle 0.732356 1527 microfibril 0.732355 32559 adenyl ribonucleotide binding 0.732244 43229 intracellular organelle 0.732097 15030 Cajal body 0.732026 16192 vesicle-mediated transport 0.731815 44428 nuclear part 0.731640 12505 endomembrane system 0.731026 5887 integral to plasma membrane 0.730932 32039 integrator complex 0.730646 5524 ATP binding 0.730617 5743 mitochondrial inner membrane 0.730549 16301 kinase activity 0.730403 43190 ATP-binding cassette (ABC) transporter complex 0.730308 5868 cytoplasmic dynein complex 0.730213 16925 protein sumoylation 0.730175 51258 protein polymerization 0.730066 16602 CCAAT-binding factor complex 0.730006 7249 I-kappaB kinase/NF-kappaB cascade 0.729914 9056 catabolic process 0.729441 16072 rRNA metabolic process 0.729383 42611 MHC protein complex 0.729317 70161 anchoring junction 0.729137 16788 hydrolase activity, acting on ester bonds 0.729032 50794 regulation of cellular process 0.728671 51244 regulation of cellular process 0.728671 30532 small nuclear ribonucleoprotein complex 0.728538 1608 nucleotide receptor activity, G-protein coupled 0.728481 16018 cyclosporin A binding 0.728402 30674 protein binding, bridging 0.728044 16310 phosphorylation 0.727947 44421 extracellular region part 0.727865 4722 protein serine/threonine phosphatase activity 0.727547 5739 mitochondrion 0.727332 48471 perinuclear region of cytoplasm 0.726887 19198 transmembrane receptor protein phosphatase activity 0.726886 5001 transmembrane receptor protein tyrosine phosphatase activity 0.726886 16265 death 0.726803 48731 system development 0.726615 44267 cellular protein metabolic process 0.726215 5875 microtubule associated complex 0.726177 5768 endosome 0.726081 34707 chloride channel complex 0.726020 48285 organelle fission 0.725823 5932 microtubule basal body 0.725561 6796 phosphate metabolic process 0.725491 6793 phosphorus metabolic process 0.725491 16874 ligase activity 0.725399 6364 rRNA processing 0.725355 6955 immune response 0.725261 5484 SNAP receptor activity 0.725249 5834 heterotrimeric G-protein complex 0.724975 34961 cellular macromolecule biosynthetic process 0.724907 34645 cellular macromolecule biosynthetic process 0.724907 8219 cell death 0.724813 70003 threonine-type peptidase activity 0.724232 4298 threonine-type endopeptidase activity 0.724232 5604 basement membrane 0.723756 50953 sensory perception of light stimulus 0.723637 7601 visual perception 0.723637 16773 phosphotransferase activity, alcohol group as acceptor 0.723359 4499 flavin-containing monooxygenase activity 0.723161 16592 mediator complex 0.722965 48609 reproductive process in a multicellular organism 0.722890 3714 transcription corepressor activity 0.722756 17076 purine nucleotide binding 0.722661 30574 collagen catabolic process 0.722634 30008 TRAPP complex 0.722508 16459 myosin complex 0.722469 17150 tRNA dihydrouridine synthase activity 0.722448 4864 phosphoprotein phosphatase inhibitor activity 0.722199 22843 voltage-gated cation channel activity 0.721746 17137 Rab GTPase binding 0.721699 7160 cell-matrix adhesion 0.721664 3702 RNA polymerase II transcription factor activity 0.721312 19538 protein metabolic process 0.721077 19212 phosphatase inhibitor activity 0.721058 45028 purinergic nucleotide receptor activity, G-protein coupled 0.720929 6411 protein metabolic process 0.720917 4522 pancreatic ribonuclease activity 0.720860 8289 lipid binding 0.720792 16741 transferase activity, transferring one-carbon groups 0.720612 16070 RNA metabolic process 0.720610 3847 1-alkyl-2-acetylglycerophosphocholine esterase activity 0.720589 42612 MHC class I protein complex 0.720473 15629 actin cytoskeleton 0.720138 7067 mitosis 0.719896 280 nuclear division 0.719896 43227 membrane-bounded organelle 0.719324 4385 guanylate kinase activity 0.719130 43231 intracellular membrane-bounded organelle 0.719126 6468 protein amino acid phosphorylation 0.719052 7049 cell cycle 0.718869 7223 Wnt receptor signaling pathway, calcium modulating pathway 0.718848 6914 autophagy 0.718839 5543 phospholipid binding 0.718549 166 nucleotide binding 0.717937 4115 3',5'-cyclic-AMP phosphodiesterase activity 0.717908 46578 regulation of Ras protein signal transduction 0.717873 16604 nuclear body 0.717801 44036 cell wall macromolecule metabolic process 0.716775 1669 acrosomal vesicle 0.716676 8168 methyltransferase activity 0.715882 32553 ribonucleotide binding 0.715804 32555 purine ribonucleotide binding 0.715804 16302 phosphatase activity 0.715473 16818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.714907 16462 pyrophosphatase activity 0.714801 16817 hydrolase activity, acting on acid anhydrides 0.714737 8135 translation factor activity, nucleic acid binding 0.714627 145 exocyst 0.714395 16787 hydrolase activity 0.714366 5732 small nucleolar ribonucleoprotein complex 0.714353 7565 female pregnancy 0.714120 8639 small conjugating protein ligase activity 0.714052 8640 small conjugating protein ligase activity 0.714052 5922 connexon complex 0.713200 19787 small conjugating protein ligase activity 0.713044 6813 potassium ion transport 0.712438 22832 voltage-gated channel activity 0.711978 5244 voltage-gated ion channel activity 0.711978 502 proteasome complex 0.711796 30212 hyaluronan metabolic process 0.711546 30133 transport vesicle 0.711060 12501 programmed cell death 0.710542 30054 cell junction 0.710416 4035 alkaline phosphatase activity 0.709992 5737 cytoplasm 0.709836 16281 eukaryotic translation initiation factor 4F complex 0.709429 32393 MHC class I receptor activity 0.709384 17111 nucleoside-triphosphatase activity 0.709265 51082 unfolded protein binding 0.709238 4842 ubiquitin-protein ligase activity 0.709215 50874 multicellular organismal process 0.709067 32501 multicellular organismal process 0.709067 32774 RNA biosynthetic process 0.709043 16791 phosphatase activity 0.708986 16244 programmed cell death 0.708974 4065 arylsulfatase activity 0.708748 7154 cell communication 0.708584 45184 establishment of protein localization 0.708419 4969 histamine receptor activity 0.707818 15031 protein transport 0.707599 8305 integrin complex 0.707406 5520 insulin-like growth factor binding 0.707177 8527 taste receptor activity 0.706808 42379 chemokine receptor binding 0.706777 5853 eukaryotic translation elongation factor 1 complex 0.706622 6915 apoptosis 0.706396 16881 acid-amino acid ligase activity 0.705827 6888 ER to Golgi vesicle-mediated transport 0.705502 6395 RNA splicing 0.705243 19864 IgG binding 0.705150 4835 tubulin-tyrosine ligase activity 0.705105 3743 translation initiation factor activity 0.704788 6351 transcription, DNA-dependent 0.704624 17124 SH3 domain binding 0.704021 5132 interferon-alpha/beta receptor binding 0.703573 16859 cis-trans isomerase activity 0.703491 4713 protein tyrosine kinase activity 0.703343 22627 cytosolic small ribosomal subunit 0.703256 6511 ubiquitin-dependent protein catabolic process 0.702839 47760 butyrate-CoA ligase activity 0.702514 3950 NAD+ ADP-ribosyltransferase activity 0.702492 8195 phosphatidate phosphatase activity 0.702354 5783 endoplasmic reticulum 0.702268 4857 enzyme inhibitor activity 0.701974 5832 chaperonin-containing T-complex 0.701777 3779 actin binding 0.701712 7165 signal transduction 0.701373 377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 0.700550 375 RNA splicing, via transesterification reactions 0.700550 385 RNA splicing, via transesterification reactions 0.700550 398 nuclear mRNA splicing, via spliceosome 0.700550 16998 cell wall macromolecule catabolic process 0.700098 46870 cadmium ion binding 0.699797 3746 translation elongation factor activity 0.699285 16455 RNA polymerase II transcription mediator activity 0.699042 3703 general RNA polymerase II transcription factor activity 0.699042 44265 cellular macromolecule catabolic process 0.698997 43565 sequence-specific DNA binding 0.698743 7517 muscle organ development 0.698734 34962 cellular macromolecule catabolic process 0.698643 3774 motor activity 0.698478 8076 voltage-gated potassium channel complex 0.698343 34705 potassium channel complex 0.698343 30286 dynein complex 0.698259 6394 RNA processing 0.698215 6968 cellular defense response 0.697735 9552 gamete generation 0.697690 32993 protein-DNA complex 0.697662 8009 chemokine activity 0.697290 5911 cell-cell junction 0.697258 34728 nucleosome organization 0.696966 5794 Golgi apparatus 0.696847 5249 voltage-gated potassium channel activity 0.696842 4672 protein kinase activity 0.696788 5267 potassium channel activity 0.696743 4869 cysteine-type endopeptidase inhibitor activity 0.696738 50222 protein kinase activity 0.696429 5852 eukaryotic translation initiation factor 3 complex 0.696366 50699 WW domain binding 0.696284 5070 SH3/SH2 adaptor activity 0.696065 30234 enzyme regulator activity 0.695929 5523 tropomyosin binding 0.694883 31202 RNA splicing, via transesterification reactions 0.694857 43087 regulation of GTPase activity 0.694426 5003 ephrin receptor activity 0.694384 5179 hormone activity 0.694327 5815 microtubule organizing center 0.694035 19843 rRNA binding 0.693440 48232 male gamete generation 0.693292 7283 spermatogenesis 0.693292 6350 transcription 0.693197 19222 regulation of metabolic process 0.692882 6396 RNA processing 0.692692 16272 prefoldin complex 0.692546 4427 inorganic diphosphatase activity 0.691925 5869 dynactin complex 0.691622 7276 gamete generation 0.691359 16805 dipeptidase activity 0.691207 70035 purine NTP-dependent helicase activity 0.691014 8026 ATP-dependent helicase activity 0.691014 6413 translational initiation 0.690059 8238 exopeptidase activity 0.689377 7018 microtubule-based movement 0.689372 3755 peptidyl-prolyl cis-trans isomerase activity 0.689222 6457 protein folding 0.688677 35023 regulation of Rho protein signal transduction 0.688630 15935 small ribosomal subunit 0.688359 15020 glucuronosyltransferase activity 0.688253 932 cytoplasmic mRNA processing body 0.688220 5088 Ras guanyl-nucleotide exchange factor activity 0.687885 7338 single fertilization 0.687482 9057 macromolecule catabolic process 0.687118 43285 macromolecule catabolic process 0.687118 51056 regulation of small GTPase mediated signal transduction 0.686952 6366 transcription from RNA polymerase II promoter 0.686361 8158 hedgehog receptor activity 0.685506 8433 guanyl-nucleotide exchange factor activity 0.685421 19839 guanyl-nucleotide exchange factor activity 0.685421 4180 carboxypeptidase activity 0.684839 31323 regulation of cellular metabolic process 0.684678 4386 helicase activity 0.684607 8047 enzyme activator activity 0.684558 8239 dipeptidyl-peptidase activity 0.684213 4220 cysteine-type peptidase activity 0.684207 42254 ribosome biogenesis 0.684123 775 chromosome, centromeric region 0.684036 31105 septin complex 0.683705 70001 aspartic-type peptidase activity 0.683435 4190 aspartic-type endopeptidase activity 0.683435 8180 signalosome 0.683401 43232 intracellular non-membrane-bounded organelle 0.682976 43228 non-membrane-bounded organelle 0.682976 19898 extrinsic to membrane 0.682868 4674 protein serine/threonine kinase activity 0.682200 32318 regulation of Ras GTPase activity 0.682050 16311 dephosphorylation 0.681994 65004 protein-DNA complex assembly 0.681528 3777 microtubule motor activity 0.681261 7166 cell surface receptor linked signal transduction 0.680273 30530 heterogeneous nuclear ribonucleoprotein complex 0.679761 6470 protein amino acid dephosphorylation 0.679276 4715 non-membrane spanning protein tyrosine kinase activity 0.679081 16071 mRNA metabolic process 0.678355 9898 internal side of plasma membrane 0.677492 5198 structural molecule activity 0.677432 4726 non-membrane spanning protein tyrosine phosphatase activity 0.677238 44430 cytoskeletal part 0.676863 5793 ER-Golgi intermediate compartment 0.676523 3008 system process 0.676047 5813 centrosome 0.675812 16339 calcium-dependent cell-cell adhesion 0.675684 5856 cytoskeleton 0.675517 35091 phosphoinositide binding 0.675478 5874 microtubule 0.675405 32012 regulation of ARF protein signal transduction 0.675359 8235 metalloexopeptidase activity 0.675028 6334 nucleosome assembly 0.674741 7399 nervous system development 0.674443 5083 small GTPase regulator activity 0.673847 4177 aminopeptidase activity 0.673405 19992 diacylglycerol binding 0.673348 5763 mitochondrial small ribosomal subunit 0.673263 314 organellar small ribosomal subunit 0.673263 50909 sensory perception of taste 0.672546 5086 ARF guanyl-nucleotide exchange factor activity 0.671944 16055 Wnt receptor signaling pathway 0.671489 30528 transcription regulator activity 0.671314 5099 Ras GTPase activator activity 0.671049 16012 sarcoglycan complex 0.669854 4653 polypeptide N-acetylgalactosaminyltransferase activity 0.669640 5544 calcium-dependent phospholipid binding 0.669625 80090 regulation of primary metabolic process 0.668762 5089 Rho guanyl-nucleotide exchange factor activity 0.668367 30246 carbohydrate binding 0.668011 5762 mitochondrial large ribosomal subunit 0.667926 315 organellar large ribosomal subunit 0.667926 4197 cysteine-type endopeptidase activity 0.667632 60255 regulation of macromolecule metabolic process 0.667250 4721 phosphoprotein phosphatase activity 0.666640 245 spliceosome assembly 0.666326 6412 translation 0.666202 4725 protein tyrosine phosphatase activity 0.665498 5212 structural constituent of eye lens 0.664899 5886 plasma membrane 0.664063 30529 ribonucleoprotein complex 0.663819 16790 thiolester hydrolase activity 0.663644 6397 mRNA processing 0.662460 16607 nuclear speck 0.662289 5761 mitochondrial ribosome 0.661815 313 organellar ribosome 0.661815 4871 signal transducer activity 0.661711 60089 molecular transducer activity 0.661711 5044 scavenger receptor activity 0.660834 6414 translational elongation 0.660324 4364 glutathione transferase activity 0.659949 8138 protein tyrosine/serine/threonine phosphatase activity 0.659949 4181 metallocarboxypeptidase activity 0.659222 786 nucleosome 0.659127 7275 multicellular organismal development 0.659059 8060 ARF GTPase activator activity 0.658211 5730 nucleolus 0.657463 5085 guanyl-nucleotide exchange factor activity 0.657252 1533 cornified envelope 0.657046 30280 structural constituent of epidermis 0.656667 3924 GTPase activity 0.656599 32312 regulation of ARF GTPase activity 0.656451 30057 desmosome 0.654335 6829 zinc ion transport 0.653441 33279 ribosomal subunit 0.653319 5540 hyaluronic acid binding 0.652704 7264 small GTPase mediated signal transduction 0.651531 3723 RNA binding 0.650735 8380 RNA splicing 0.650699 9889 regulation of biosynthetic process 0.650586 31326 regulation of cellular biosynthetic process 0.649277 5689 U12-type spliceosomal complex 0.649231 31012 extracellular matrix 0.648689 5681 spliceosomal complex 0.647906 4089 carbonate dehydratase activity 0.645395 4866 endopeptidase inhibitor activity 0.644829 5509 calcium ion binding 0.644487 4175 endopeptidase activity 0.644017 16020 membrane 0.643457 8233 peptidase activity 0.643429 4693 cyclin-dependent protein kinase activity 0.642766 16337 cell-cell adhesion 0.642302 16809 endopeptidase activity 0.642236 70011 peptidase activity, acting on L-amino acid peptides 0.641555 30163 protein catabolic process 0.641553 7155 cell adhesion 0.640817 22610 biological adhesion 0.640693 60589 nucleoside-triphosphatase regulator activity 0.640436 6508 proteolysis 0.639573 43167 ion binding 0.639550 51171 regulation of nitrogen compound metabolic process 0.639454 44257 cellular protein catabolic process 0.638970 51603 proteolysis involved in cellular protein catabolic process 0.637896 5578 proteinaceous extracellular matrix 0.636870 10468 regulation of gene expression 0.636598 10556 regulation of macromolecule biosynthetic process 0.636510 19219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 0.636254 5634 nucleus 0.636115 3700 transcription factor activity 0.636092 4872 receptor activity 0.635885 43169 cation binding 0.635797 7218 neuropeptide signaling pathway 0.635620 30695 GTPase regulator activity 0.635216 8237 metallopeptidase activity 0.634811 51252 regulation of RNA metabolic process 0.634806 17171 serine hydrolase activity 0.634717 44425 membrane part 0.633725 4888 transmembrane receptor activity 0.633709 46872 metal ion binding 0.633113 32561 guanyl ribonucleotide binding 0.632516 19001 guanyl nucleotide binding 0.632516 8236 serine-type peptidase activity 0.632497 8234 cysteine-type peptidase activity 0.632350 30414 peptidase inhibitor activity 0.631915 6355 regulation of transcription, DNA-dependent 0.630596 31225 anchored to membrane 0.630558 4252 serine-type endopeptidase activity 0.627683 5525 GTP binding 0.627388 43632 modification-dependent macromolecule catabolic process 0.626986 19941 modification-dependent protein catabolic process 0.626986 3735 structural constituent of ribosome 0.625465 5840 ribosome 0.624020 50877 neurological system process 0.623169 70160 occluding junction 0.622765 5923 tight junction 0.622765 15934 large ribosomal subunit 0.620624 4198 calcium-dependent cysteine-type endopeptidase activity 0.620210 4221 ubiquitin thiolesterase activity 0.619352 4222 metalloendopeptidase activity 0.617049 22625 cytosolic large ribosomal subunit 0.616956 5576 extracellular region 0.615931 31072 heat shock protein binding 0.614219 5096 GTPase activator activity 0.613961 45449 regulation of transcription 0.613434 50890 cognition 0.607687 3676 nucleic acid binding 0.606099 7186 G-protein coupled receptor protein signaling pathway 0.606066 4867 serine-type endopeptidase inhibitor activity 0.603143 16338 calcium-independent cell-cell adhesion 0.600641 3677 DNA binding 0.596212 5529 sugar binding 0.592796 31224 intrinsic to membrane 0.589448 16021 integral to membrane 0.584748 46914 transition metal ion binding 0.584109 16526 G-protein coupled receptor activity 0.584057 7600 sensory perception 0.582580 5097 Rab GTPase activator activity 0.582063 32313 regulation of Rab GTPase activity 0.580976 4930 G-protein coupled receptor activity 0.563157 5622 intracellular 0.539063 31424 keratinization 0.535818 8270 zinc ion binding 0.532876 7156 homophilic cell adhesion 0.531866 5882 intermediate filament 0.477931 45095 keratin filament 0.468257 7606 sensory perception of chemical stimulus 0.465666 7608 sensory perception of smell 0.444794 4984 olfactory receptor activity 0.423926