FTO coexpression supplement

Supplement to FTO, obesity and the brain in adolescence.
Melka MG, Gillis J, Bernard M, Abrahamowicz M, Chakravarty MM, Leonard GT, Perron M, Richer L, Veillette S, Banaschewski T, Barker GJ, Büchel C, Conrod P, Flor H, Heinz A, Garavan H, Brühl R, Mann K, Artiges E, Lourdusamy A, Lathrop M, Loth E, Schwartz Y, Frouin V, Rietschel M, Smolka MN, Ströhle A, Gallinat J, Struve M, Lattka E, Waldenberger M, Schumann G, Pavlidis P, Gaudet D, Paus T, Pausova Z pubmed reprint
 

Supplementary Files

Below are further particulars and relevant files for many of the analyses performed.
Supplemental text is available here.

 

List of human experiments
Listed by GSE id, full name, and Gemma ID The subset of experiments meeting criteria for assessment. The Gemma ID in the last column can be used to access the underlying expression data at
 
www.chibi.ubc.ca/Gemma/expressionExperiment/showExpressionExperiment.html?id=###
 
where “###” is the experiment number given, e.g., 1188

 

Unique list of annotations
The subset of the full list of annotations used to characterize expression experiments and meeting criteria for assessment.

 

Human genes
List of human gene symbols meeting criteria for assessment (inclusion in the UCSC “known gene” list and sufficient microarray experiment representation).

 

p-values and descriptors
For enrichment in the coexpression between FTO and BMP4 across the coexpression sets.

 

p-values and descriptors
For enrichment in the absolute value of coexpression between FTO and BMP4 across the coexpression sets.

 

Adipose labelled experiments
“Adipose” experiments contributing to enrichment score in the coexpression between FTO and BMP4 across the coexpression sets. Datatsets are ordered by decreasing contribution.

 

Embryo labelled experiments
“Embryo” experiments contributing to enrichment score in the coexpression between FTO and BMP4 across the coexpression sets. Datatsets are ordered by decreasing contribution.

 

Genes ranked by similarity to FTO-BMP4
All genes ranked by their similarity across experimental profiles to that between FTO and BMP4 (that is, similar to FTO when BMP4 is).

 

Subnetwork interaction data
The interactions within the subnetwork for that subset of genes.