Marta Guarna

Marta GuarnaPosition: Scientific Director, Bee IPM

 

E-mail: marta.guarna[at]outlook.com

 

Biochemist, University of Buenos Aires
PhD, Biology Department, New York University
Postdoctoral Fellow, MSL, University of British Columbia

 

Scientist, Micrologix Biotech
Team Leader, Molecular and Cell Biology, MIGENIX
Director, Biology, Inimex Pharmaceuticals
Sr. Scientist, Aquinox Pharmaceauticals

 

SELECTED PUBLICATIONS and PATENTS

 

  1. Guarna MM, Melathopoulos AP, Huxter E, Iovinella I, Parker R, Stoynov N, Tam A, Moon KM, Chan QWT, Pelosi P, White R, Pernal S F, Foster LJ. “A Search for Protein Biomarkers Links Olfactory Signal Transduction to Social Immunity.” Submitted
  2. Parker R, Guarna MM, Melathopoulos AP, Moon KM, White R, Huxter E, Pernal SF, Foster LJ. “Correlation of proteome-wide changes with social immunity behaviors provides insight into resistance to the parasitic mite, Varroa destructor, in the honey bee (Apis mellifera)”. Genome Biol. 2012; 13(9): R81 PMID 23021491
  3. Ren Q, Wang Q S, Firth A E, Chan M M Y, Gouw J W, Guarna M M, Foster L J, Atkins J F, Jan E. “Alternative reading frame selection mediated by a tRNA-like domain of an internal ribosome entry site.” Proc Natl Acad Sci U S A. 2012;109(11):E630-9. PMID 22247292
  4. Chan MM, Choi SY, Chan QW, Li P, Guarna* MM, Foster* LJ. “Proteome profile and lentiviral transduction of cultured honey bee (Apis mellifera L.) cells”. Insect Mol Biol. 2010 19: 653-658. *Shared corresponding authorship.PMID 20546039
  5. Parker R, Melathopoulos AP, White R, Pernal SF, Guarna MM and Foster LJ “Ecological Adaptation of Diverse Honey Bee (Apis mellifera) Populations.” PLoS One. 2010 5(6):e11096. PMID 20559562
  6. Yu HB, Kielczewska A, Rozek A, Takenaka S, Li Y, Thorson L, Hancock RE, Guarna MM, North JR, Foster LJ, Donini O, Finlay BB. “Sequestosome-1/p62 is the key intracellular target of innate defense regulator peptide”. (2009) J Biol Chem 284:36007-36011. PMID 19850933
  7. Cameron DR, Guarna, MM, and Metlitskaia L. “Compositions and Methods for Treating Hyperproliferative Disease”. (2008) WO 2008/080223, US 2008/0171783.
  8. Scott MG, Dullaghan E, Mookherjee N, Glavas N, Waldbrook M, Thompson A, Wang A, Lee K, Doria S, Hamill P, Yu JJ, Li Y, Donini O, Guarna MM, Finlay B.B, North JR and Hancock RE. “An Anti-infective Peptide that Selectively Modulates the Innate Immune Response”. (2007) Nature Biotechnol 25: 465-472. PMID 17384586
  9. Guarna MM, Coulson R and Rubinchik E. “Anti-inflammatory Activity of Cationic Peptides: Application to the Treatment of Acne Vulgaris”. (2006) FEMS Microbiol Lett 257: 1-6. PMID 16553825
  10. Jervis EJ, Guarna MM, Doheny JG, Haynes CA and Kilburn DG. “Dynamic Localization and Persistent Stimulation of Factor-dependent Cells by a Stem Cell Factor / Cellulose Binding Domain Fusion Protein”. (2005) Biotechnol Bioeng 91: 314-324. PMID 15948140
  11. Boyd V, Guarna MM, Metlitskaia L and Kerry C. “Non-Nucleoside Anti- Hepacivirus Agents”. (2005) US PTO 60/693569.
  12. Metlitskaia L, Cabralda JE, Suleman D, Brinkman JN, Bartfeld D and Guarna MM. “Recombinant Antimicrobial Peptides Efficiently Produced Using Novel Cloning and Purification Processes”. (2004) Biotechnol Appl Biochem 39: 339-345. PMID 15154847
  13. McNicol PJ, Rubinchik E, Cameron D, Pawlak SK. and Guarna MM. “Antimicrobial and Anti-Inflammatory Peptides”. (2003) US 2003/0148945 A1; WO03/018619.
  14. Guarna MM, Chen Y, Cory R, Brinkman J, Cabralda J, Metlitskaia L and Suleman D. “Methods for Producing Modified Anti-infective Peptides”. (2003) US 2003/0219854.