FACULTY

Dr. Leonard J. Foster, Director

 

Cell Biology Proteomics

Our group is interested in a multidisciplinary approach to relevant cell biological problems. We develop and apply quantitative proteomic methods to questions involving organelles and how the composition of these compartments change when antagonized.

 

Read more

Dr. Jörg Gsponer

 

Computational Biology of Protein Structure and Interaction

Our group is interested in the mechanism of protein-mediated intracellular signal transduction and how this vital process is affected in neurodegenerative disorders. We develop and apply computational means to determine and analyze (i) the structures of signaling proteins and protein complexes and (ii) the constraints that structural features put on regulation, evolution and interaction of signaling proteins.

 

Read more

Dr. Carl L. Hansen

 

Microsystems Tools in Biology

Our research is focused on the development of new microsystems tools for biology and on the validation of these tools in the context of research questions in basic and applied biomedical research. In particular, we are interested in the themes of single cell analysis, genomics, and diagnostics.

 

Read more

Dr. Martin Hirst

 

Epigenomics

Our lab examines the role of epigenetics in cancer and investigates the therapeutic potential of interventions directed at epigenetic processes. We approach this from an epigenomic perspective by combining innovative molecular biology and computational techniques with genome wide detection platforms.

 

Read more

Dr. Thibault Mayor

 

Ubiquitin Proteomics

Using a combination of cell biology and proteomics, our lab is interested in understanding how the cell recognizes misfolded and aggregating proteins to target them for ubiquitylation and proteolysis.

 

Read more

Dr. Paul Pavlidis

 

Informatics and Neuroscience

Our group is focused on the development of tools and methods for informatics and their application to problems in neuroscience.

 

Read more

Dr. Stephen G. Withers

Chemical Biology: Directed Evolution and Inhibitor Screening

The Withers laboratory brings the tools of organic chemistry, biochemistry and molecular biology to bear on the identification, development and evolution of novel biocatalysts, as well as on the development of potent enzyme inhibitors, both by design and by screening. We have a particular interest in the enzymes involved in the assembly and degradation of glycans, with applications ranging from glycoprotein and glycolipid assembly through development of antivirals to biomass conversion.

 

Read more

CaraHaney

Dr. Cara Haney

Microbial Communities

The Haney lab is interested in the genetic and metabolic factors that regulate assembly of host-associated microbial communities.

 

Read more